Danio rerio

0 known processes

eif2d

eukaryotic translation initiation factor 2D

(Aliases: zgc:63669,lgtn,MGC63669)

eif2d biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule metabolic process GO:0044260 391 0.215
cellular nitrogen compound metabolic process GO:0034641 290 0.215
regulation of gene expression GO:0010468 265 0.162
larval development GO:0002164 2 0.142
regulation of nitrogen compound metabolic process GO:0051171 251 0.127
regulation of metabolic process GO:0019222 359 0.123
cellular biosynthetic process GO:0044249 286 0.122
gene expression GO:0010467 252 0.111
mitotic g2 dna damage checkpoint GO:0007095 3 0.111
positive regulation of biological process GO:0048518 253 0.104
organic substance biosynthetic process GO:1901576 289 0.082
mitotic dna integrity checkpoint GO:0044774 4 0.078
mitotic g2 m transition checkpoint GO:0044818 3 0.075
negative regulation of cellular process GO:0048523 283 0.071
mitotic dna damage checkpoint GO:0044773 4 0.068
nitrogen compound metabolic process GO:0006807 319 0.068
cellular macromolecule biosynthetic process GO:0034645 224 0.067
multicellular organism growth GO:0035264 4 0.067
cellular nitrogen compound biosynthetic process GO:0044271 218 0.064
regulation of rna metabolic process GO:0051252 224 0.062
heterocycle metabolic process GO:0046483 290 0.060
regulation of transcription dna templated GO:0006355 213 0.056
regulation of macromolecule metabolic process GO:0060255 317 0.054
cytokinesis GO:0000910 3 0.053
protein modification by small protein removal GO:0070646 1 0.051
positive regulation of cellular catabolic process GO:0031331 3 0.051
central nervous system development GO:0007417 387 0.051
regulation of macromolecule biosynthetic process GO:0010556 225 0.049
signal transduction GO:0007165 455 0.047
response to chemical GO:0042221 320 0.047
small molecule metabolic process GO:0044281 77 0.045
nucleic acid templated transcription GO:0097659 181 0.043
nucleic acid metabolic process GO:0090304 244 0.042
regulation of cellular biosynthetic process GO:0031326 245 0.041
regulation of cellular metabolic process GO:0031323 320 0.040
biosynthetic process GO:0009058 294 0.040
protein metabolic process GO:0019538 183 0.040
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.039
regulation of multicellular organism growth GO:0040014 4 0.039
stem cell proliferation GO:0072089 4 0.038
production of molecular mediator of immune response GO:0002440 2 0.038
aging GO:0007568 2 0.038
cellular aromatic compound metabolic process GO:0006725 295 0.037
macromolecule biosynthetic process GO:0009059 227 0.037
regulation of primary metabolic process GO:0080090 311 0.037
positive regulation of cellular process GO:0048522 201 0.037
lipid storage GO:0019915 1 0.036
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.033
organic cyclic compound metabolic process GO:1901360 301 0.033
regulation of biological quality GO:0065008 263 0.033
g2 dna damage checkpoint GO:0031572 3 0.033
regulation of protein catabolic process GO:0042176 1 0.031
cellular response to external stimulus GO:0071496 2 0.030
response to nutrient GO:0007584 3 0.030
organonitrogen compound metabolic process GO:1901564 74 0.030
nucleobase containing compound metabolic process GO:0006139 274 0.029
apoptotic process GO:0006915 116 0.029
maintenance of location GO:0051235 4 0.029
response to external stimulus GO:0009605 264 0.028
regulation of production of molecular mediator of immune response GO:0002700 1 0.028
rna localization GO:0006403 4 0.028
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.028
positive regulation of catabolic process GO:0009896 4 0.028
regulation of stem cell proliferation GO:0072091 2 0.028
development of primary female sexual characteristics GO:0046545 4 0.028
negative regulation of biological process GO:0048519 304 0.028
ribonucleoside monophosphate catabolic process GO:0009158 4 0.028
mitochondrion organization GO:0007005 4 0.027
guanosine containing compound catabolic process GO:1901069 2 0.027
regulation of biosynthetic process GO:0009889 250 0.027
translational initiation GO:0006413 3 0.026
negative regulation of protein phosphorylation GO:0001933 4 0.026
autophagy GO:0006914 4 0.026
carboxylic acid metabolic process GO:0019752 22 0.025
response to stress GO:0006950 263 0.025
cellular protein metabolic process GO:0044267 129 0.025
rna processing GO:0006396 25 0.025
organic acid metabolic process GO:0006082 31 0.025
female sex differentiation GO:0046660 4 0.025
gtp catabolic process GO:0006184 2 0.025
viral process GO:0016032 1 0.025
tube morphogenesis GO:0035239 349 0.025
negative regulation of gene expression GO:0010629 65 0.025
regulation of rna biosynthetic process GO:2001141 213 0.024
stem cell division GO:0017145 1 0.024
multi organism process GO:0051704 134 0.024
regulation of multicellular organismal process GO:0051239 277 0.024
regulation of dna templated transcription elongation GO:0032784 3 0.024
positive regulation of cell activation GO:0050867 1 0.024
regulation of nucleotide catabolic process GO:0030811 2 0.024
regulation of protein transport GO:0051223 3 0.024
cellular component disassembly GO:0022411 1 0.023
protein stabilization GO:0050821 2 0.023
single organism biosynthetic process GO:0044711 71 0.023
amine metabolic process GO:0009308 2 0.023
regulation of nucleoside metabolic process GO:0009118 2 0.023
positive regulation of gtp catabolic process GO:0033126 1 0.023
synaptic growth at neuromuscular junction GO:0051124 2 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.022
response to biotic stimulus GO:0009607 97 0.022
morphogenesis of an epithelium GO:0002009 333 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
female gonad development GO:0008585 4 0.021
cellular amine metabolic process GO:0044106 2 0.021
growth GO:0040007 174 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
wnt signaling pathway GO:0016055 80 0.021
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.021
positive regulation of gtpase activity GO:0043547 1 0.021
aromatic compound biosynthetic process GO:0019438 217 0.021
regulation of response to biotic stimulus GO:0002831 2 0.020
rna biosynthetic process GO:0032774 181 0.020
g2 m transition of mitotic cell cycle GO:0000086 4 0.020
positive regulation of stem cell proliferation GO:2000648 1 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
chemosensory behavior GO:0007635 1 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.019
positive regulation of cell adhesion GO:0045785 1 0.019
phagocytosis GO:0006909 3 0.019
atp catabolic process GO:0006200 4 0.019
positive regulation of transport GO:0051050 2 0.019
single organism metabolic process GO:0044710 217 0.019
gtp metabolic process GO:0046039 4 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
regulation of response to stimulus GO:0048583 269 0.018
positive regulation of nucleotide catabolic process GO:0030813 1 0.018
oxoacid metabolic process GO:0043436 31 0.018
system process GO:0003008 185 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
negative regulation of synapse assembly GO:0051964 2 0.018
cellular component biogenesis GO:0044085 178 0.018
developmental growth GO:0048589 166 0.018
purine nucleoside monophosphate catabolic process GO:0009128 4 0.018
dna templated transcription elongation GO:0006354 3 0.018
regulation of developmental process GO:0050793 247 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
cellular protein catabolic process GO:0044257 4 0.018
lateral inhibition GO:0046331 1 0.018
regulation of cell activation GO:0050865 1 0.018
phosphate containing compound metabolic process GO:0006796 108 0.018
regulation of gtpase activity GO:0043087 2 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
cell death GO:0008219 121 0.017
regulation of cell communication GO:0010646 232 0.017
neuroblast proliferation GO:0007405 2 0.017
cell cycle g2 m phase transition GO:0044839 4 0.017
mrna 3 end processing GO:0031124 2 0.017
regulation of mitotic cell cycle phase transition GO:1901990 8 0.017
hepaticobiliary system development GO:0061008 98 0.017
response to other organism GO:0051707 97 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.017
regionalization GO:0003002 274 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
response to uv GO:0009411 3 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
response to bacterium GO:0009617 58 0.017
regulation of binding GO:0051098 3 0.017
regulation of synapse organization GO:0050807 3 0.017
positive regulation of dna metabolic process GO:0051054 1 0.016
negative regulation of defense response GO:0031348 2 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.016
action potential GO:0001508 19 0.016
regulation of synapse assembly GO:0051963 3 0.016
positive regulation of cell cycle GO:0045787 3 0.016
liver development GO:0001889 96 0.016
regulation of dna recombination GO:0000018 2 0.016
rna transport GO:0050658 2 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
negative regulation of dna metabolic process GO:0051053 4 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
immunoglobulin production GO:0002377 1 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
protein localization to plasma membrane GO:0072659 1 0.015
regulation of signaling GO:0023051 235 0.015
immune system process GO:0002376 241 0.015
macromolecule modification GO:0043412 111 0.015
response to drug GO:0042493 3 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
programmed cell death GO:0012501 119 0.015
negative regulation of metabolic process GO:0009892 86 0.015
somitogenesis GO:0001756 87 0.015
regulation of cell cycle phase transition GO:1901987 8 0.015
peptide metabolic process GO:0006518 1 0.015
carbohydrate derivative metabolic process GO:1901135 61 0.015
chromosome organization involved in meiosis GO:0070192 1 0.014
brain development GO:0007420 293 0.014
cellular ketone metabolic process GO:0042180 11 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
positive regulation of notch signaling pathway GO:0045747 3 0.014
cellular response to nutrient levels GO:0031669 2 0.014
meiosis i GO:0007127 1 0.014
protein heterooligomerization GO:0051291 1 0.014
response to ketone GO:1901654 1 0.014
glucose homeostasis GO:0042593 1 0.014
regulation of apoptotic process GO:0042981 98 0.014
mitotic cell cycle checkpoint GO:0007093 5 0.014
death GO:0016265 121 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
cell projection morphogenesis GO:0048858 244 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
protein dephosphorylation GO:0006470 3 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
negative regulation of biosynthetic process GO:0009890 55 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
axonogenesis GO:0007409 152 0.013
nuclear pore organization GO:0006999 2 0.013
chordate embryonic development GO:0043009 271 0.013
adult behavior GO:0030534 2 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
rna metabolic process GO:0016070 219 0.013
regulation of establishment of protein localization GO:0070201 4 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
regulation of mesenchymal cell proliferation GO:0010464 1 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
regulation of cell death GO:0010941 103 0.013
regulation of signal transduction GO:0009966 225 0.013
gastrulation GO:0007369 208 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.013
segmentation GO:0035282 97 0.013
mitotic recombination GO:0006312 2 0.013
iron ion homeostasis GO:0055072 4 0.013
protein modification process GO:0036211 100 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
heterocycle catabolic process GO:0046700 15 0.013
determination of bilateral symmetry GO:0009855 204 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
organelle organization GO:0006996 227 0.013
specification of symmetry GO:0009799 204 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
double strand break repair GO:0006302 3 0.013
positive regulation of metabolic process GO:0009893 108 0.012
cellular component morphogenesis GO:0032989 336 0.012
generation of neurons GO:0048699 385 0.012
mrna export from nucleus GO:0006406 1 0.012
mesenchymal cell proliferation GO:0010463 1 0.012
response to monosaccharide GO:0034284 3 0.012
cell surface receptor signaling pathway GO:0007166 325 0.012
meiotic chromosome segregation GO:0045132 3 0.012
neuronal action potential GO:0019228 18 0.012
nucleobase containing compound transport GO:0015931 2 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
regulation of cytokine production GO:0001817 3 0.012
mrna transport GO:0051028 2 0.012
head development GO:0060322 303 0.012
skeletal muscle organ development GO:0060538 78 0.012
double strand break repair via homologous recombination GO:0000724 1 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
alternative mrna splicing via spliceosome GO:0000380 1 0.012
cell cycle GO:0007049 93 0.012
protein polymerization GO:0051258 4 0.012
regulation of programmed cell death GO:0043067 101 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.012
regulation of dna replication GO:0006275 3 0.012
cell morphogenesis GO:0000902 289 0.011
digestive system development GO:0055123 289 0.011
negative regulation of cell cycle process GO:0010948 9 0.011
cellular response to starvation GO:0009267 1 0.011
secondary metabolic process GO:0019748 3 0.011
interspecies interaction between organisms GO:0044419 4 0.011
response to external biotic stimulus GO:0043207 97 0.011
carbohydrate homeostasis GO:0033500 1 0.011
response to hexose GO:0009746 3 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
somatic cell dna recombination GO:0016444 1 0.011
positive regulation of protein kinase b signaling GO:0051897 1 0.011
positive regulation of leukocyte differentiation GO:1902107 1 0.011
cell projection organization GO:0030030 284 0.011
response to carbohydrate GO:0009743 3 0.011
muscle structure development GO:0061061 196 0.011
positive regulation of secretion GO:0051047 1 0.011
multi organism cellular process GO:0044764 2 0.011
regulation of protein binding GO:0043393 3 0.011
gland development GO:0048732 143 0.011
neurological system process GO:0050877 62 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
response to glucose GO:0009749 3 0.011
nucleobase containing small molecule metabolic process GO:0055086 32 0.011
response to corticosteroid GO:0031960 1 0.011
ameboidal type cell migration GO:0001667 143 0.011
stem cell maintenance GO:0019827 4 0.011
embryonic organ development GO:0048568 381 0.011
cellular response to nutrient GO:0031670 1 0.011
negative regulation of mitotic cell cycle GO:0045930 11 0.011
ovulation cycle GO:0042698 2 0.010
negative regulation of cellular biosynthetic process GO:0031327 55 0.010
nuclear export GO:0051168 1 0.010
cellular amino acid metabolic process GO:0006520 7 0.010
embryonic digestive tract development GO:0048566 4 0.010
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.010
epithelial cell morphogenesis GO:0003382 2 0.010
digestive tract development GO:0048565 265 0.010
embryonic organ morphogenesis GO:0048562 274 0.010

eif2d disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.031
inherited metabolic disorder DOID:655 0 0.031
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
cardiovascular system disease DOID:1287 0 0.013
musculoskeletal system disease DOID:17 0 0.011
sensory system disease DOID:0050155 0 0.011