Danio rerio

0 known processes

ube2w

ubiquitin-conjugating enzyme E2W (putative)

(Aliases: im:6905459,si:ch211-193n21.4)

ube2w biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.068
maintenance of location GO:0051235 4 0.046
positive regulation of transport GO:0051050 2 0.046
aging GO:0007568 2 0.045
ubiquitin dependent protein catabolic process GO:0006511 3 0.035
Mouse
cellular protein catabolic process GO:0044257 4 0.035
Mouse
protein localization to plasma membrane GO:0072659 1 0.034
modification dependent protein catabolic process GO:0019941 3 0.033
Mouse
multicellular organism growth GO:0035264 4 0.033
establishment of protein localization to organelle GO:0072594 4 0.032
phagocytosis GO:0006909 3 0.032
lipid storage GO:0019915 1 0.032
signal transduction GO:0007165 455 0.031
regulation of protein complex assembly GO:0043254 3 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.030
Mouse
amine metabolic process GO:0009308 2 0.030
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.028
Mouse
autophagy GO:0006914 4 0.028
single organism localization GO:1902578 225 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
response to chemical GO:0042221 320 0.028
Mouse
organelle fusion GO:0048284 3 0.028
protein localization to nucleus GO:0034504 3 0.028
endosomal transport GO:0016197 2 0.027
meiotic nuclear division GO:0007126 4 0.027
golgi vesicle transport GO:0048193 3 0.027
nuclear transport GO:0051169 4 0.027
positive regulation of catabolic process GO:0009896 4 0.027
response to drug GO:0042493 3 0.026
membrane fusion GO:0061025 2 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
cellular amine metabolic process GO:0044106 2 0.026
modification dependent macromolecule catabolic process GO:0043632 3 0.026
Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.025
protein import GO:0017038 3 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
cellular nitrogen compound metabolic process GO:0034641 290 0.025
single organism metabolic process GO:0044710 217 0.025
positive regulation of cell cycle GO:0045787 3 0.024
regulation of protein transport GO:0051223 3 0.024
nitrogen compound metabolic process GO:0006807 319 0.024
rna metabolic process GO:0016070 219 0.024
response to stress GO:0006950 263 0.024
Mouse
single organism membrane fusion GO:0044801 2 0.024
nucleobase containing compound metabolic process GO:0006139 274 0.024
gtp catabolic process GO:0006184 2 0.024
meiotic cell cycle process GO:1903046 3 0.023
regulation of metabolic process GO:0019222 359 0.023
regulation of binding GO:0051098 3 0.023
mitochondrion organization GO:0007005 4 0.023
gene expression GO:0010467 252 0.023
cellular aromatic compound metabolic process GO:0006725 295 0.023
regulation of cytokine production GO:0001817 3 0.022
system process GO:0003008 185 0.022
guanosine containing compound metabolic process GO:1901068 4 0.022
organic cyclic compound metabolic process GO:1901360 301 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
cell surface receptor signaling pathway GO:0007166 325 0.022
proteasomal protein catabolic process GO:0010498 2 0.021
Mouse
gtp metabolic process GO:0046039 4 0.021
single organism nuclear import GO:1902593 3 0.021
cellular component disassembly GO:0022411 1 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
regulation of synaptic plasticity GO:0048167 1 0.021
establishment of localization GO:0051234 244 0.021
response to topologically incorrect protein GO:0035966 2 0.021
Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
rna localization GO:0006403 4 0.021
nucleic acid metabolic process GO:0090304 244 0.021
organic substance biosynthetic process GO:1901576 289 0.021
stem cell maintenance GO:0019827 4 0.021
regulation of protein catabolic process GO:0042176 1 0.021
regulation of intracellular protein transport GO:0033157 3 0.021
cytokinesis GO:0000910 3 0.021
adult behavior GO:0030534 2 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
cellular biosynthetic process GO:0044249 286 0.021
cognition GO:0050890 1 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.020
cellular macromolecule metabolic process GO:0044260 391 0.020
Human Mouse
cellular response to external stimulus GO:0071496 2 0.020
protein metabolic process GO:0019538 183 0.020
Human Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
regulation of cell shape GO:0008360 1 0.020
protein polymerization GO:0051258 4 0.020
organelle organization GO:0006996 227 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
nuclear import GO:0051170 3 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
regulation of biological quality GO:0065008 263 0.020
regulation of circadian rhythm GO:0042752 4 0.020
transcription dna templated GO:0006351 181 0.020
negative regulation of cellular process GO:0048523 283 0.020
single organism transport GO:0044765 206 0.020
regulation of protein targeting GO:1903533 2 0.019
membrane invagination GO:0010324 1 0.019
g1 s transition of mitotic cell cycle GO:0000082 1 0.019
protein targeting to nucleus GO:0044744 3 0.019
stem cell proliferation GO:0072089 4 0.019
embryonic organ development GO:0048568 381 0.019
hemopoiesis GO:0030097 183 0.019
negative regulation of biological process GO:0048519 304 0.019
regulation of signaling GO:0023051 235 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
heterocycle metabolic process GO:0046483 290 0.019
cellular response to biotic stimulus GO:0071216 3 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
single organism organelle organization GO:1902589 199 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
regulation of gene expression GO:0010468 265 0.019
immune system process GO:0002376 241 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
cell migration GO:0016477 237 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
vasculature development GO:0001944 278 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.018
aromatic compound biosynthetic process GO:0019438 217 0.018
regulation of synapse organization GO:0050807 3 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
actin polymerization or depolymerization GO:0008154 2 0.018
regulation of cell activation GO:0050865 1 0.018
regulation of mrna processing GO:0050684 3 0.018
response to external stimulus GO:0009605 264 0.018
heterocycle biosynthetic process GO:0018130 215 0.018
regulation of cell communication GO:0010646 232 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
cellular ketone metabolic process GO:0042180 11 0.018
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
nucleic acid templated transcription GO:0097659 181 0.018
transport GO:0006810 220 0.018
phagocytosis engulfment GO:0006911 1 0.018
establishment of protein localization to plasma membrane GO:0090002 1 0.018
compound eye development GO:0048749 2 0.018
protein complex disassembly GO:0043241 1 0.018
synaptic vesicle localization GO:0097479 1 0.018
cellular component movement GO:0006928 335 0.018
exocytosis GO:0006887 1 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
rna biosynthetic process GO:0032774 181 0.017
chemosensory behavior GO:0007635 1 0.017
synaptic vesicle transport GO:0048489 1 0.017
protein acetylation GO:0006473 2 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
response to uv GO:0009411 3 0.017
regulation of biosynthetic process GO:0009889 250 0.017
oxoacid metabolic process GO:0043436 31 0.017
neuroblast proliferation GO:0007405 2 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
regulation of meiotic cell cycle GO:0051445 1 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
mitotic dna integrity checkpoint GO:0044774 4 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
biosynthetic process GO:0009058 294 0.017
cell cycle g1 s phase transition GO:0044843 1 0.017
central nervous system development GO:0007417 387 0.017
stem cell division GO:0017145 1 0.017
cellular response to nutrient levels GO:0031669 2 0.017
regulation of synapse assembly GO:0051963 3 0.017
cellular macromolecule biosynthetic process GO:0034645 224 0.017
regulation of reproductive process GO:2000241 4 0.017
macromolecular complex disassembly GO:0032984 1 0.017
brain development GO:0007420 293 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
cellular component assembly GO:0022607 170 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
Mouse
spermatid development GO:0007286 2 0.016
small molecule metabolic process GO:0044281 77 0.016
organic acid metabolic process GO:0006082 31 0.016
cellular respiration GO:0045333 3 0.016
protein secretion GO:0009306 1 0.016
locomotion GO:0040011 313 0.016
regulation of cellular metabolic process GO:0031323 320 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.016
protein polyubiquitination GO:0000209 4 0.016
Human
regulation of protein polymerization GO:0032271 2 0.016
establishment of synaptic vesicle localization GO:0097480 1 0.016
positive regulation of secretion GO:0051047 1 0.016
regulation of signal transduction GO:0009966 225 0.016
sensory organ development GO:0007423 393 0.016
actin filament polymerization GO:0030041 2 0.016
protein import into nucleus GO:0006606 3 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
regulation of response to stimulus GO:0048583 269 0.016
cellular carbohydrate metabolic process GO:0044262 4 0.016
cellular component biogenesis GO:0044085 178 0.015
eye development GO:0001654 277 0.015
regulation of primary metabolic process GO:0080090 311 0.015
protein dephosphorylation GO:0006470 3 0.015
peptidyl serine phosphorylation GO:0018105 1 0.015
cellular response to radiation GO:0071478 4 0.015
positive regulation of cell activation GO:0050867 1 0.015
regulation of multicellular organismal process GO:0051239 277 0.015
regulation of cell projection assembly GO:0060491 4 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
single fertilization GO:0007338 3 0.015
cellular component morphogenesis GO:0032989 336 0.015
atp catabolic process GO:0006200 4 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
cellular response to topologically incorrect protein GO:0035967 2 0.015
Mouse
spermatid differentiation GO:0048515 2 0.015
mitotic cell cycle embryonic GO:0045448 2 0.015
blood vessel development GO:0001568 246 0.015
head development GO:0060322 303 0.015
peptide transport GO:0015833 1 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
negative regulation of kinase activity GO:0033673 4 0.015
cell projection organization GO:0030030 284 0.015
alcohol biosynthetic process GO:0046165 2 0.015
immune system development GO:0002520 191 0.015
cellular response to starvation GO:0009267 1 0.015
mitotic g2 dna damage checkpoint GO:0007095 3 0.015
peptidyl serine modification GO:0018209 2 0.015
protein acylation GO:0043543 3 0.014
locomotor rhythm GO:0045475 3 0.014
positive regulation of cytokine production GO:0001819 2 0.014
tissue remodeling GO:0048771 4 0.014
protein stabilization GO:0050821 2 0.014
muscle structure development GO:0061061 196 0.014
cytoskeleton dependent cytokinesis GO:0061640 3 0.014
cell part morphogenesis GO:0032990 246 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
sequestering of metal ion GO:0051238 3 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
localization of cell GO:0051674 244 0.014
homeostatic process GO:0042592 142 0.014
regulation of transcription dna templated GO:0006355 213 0.014
post golgi vesicle mediated transport GO:0006892 1 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
cell motility GO:0048870 244 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
internal protein amino acid acetylation GO:0006475 2 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
mitotic dna damage checkpoint GO:0044773 4 0.014
sequestering of calcium ion GO:0051208 3 0.014
startle response GO:0001964 4 0.014
digestive system development GO:0055123 289 0.014
regulation of rna metabolic process GO:0051252 224 0.014
vacuolar transport GO:0007034 2 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
positive regulation of biological process GO:0048518 253 0.014
regulation of protein binding GO:0043393 3 0.014
digestive tract morphogenesis GO:0048546 231 0.014
secondary metabolic process GO:0019748 3 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
response to alkaloid GO:0043279 2 0.013
centrosome organization GO:0051297 1 0.013
heart development GO:0007507 313 0.013
regulation of metal ion transport GO:0010959 4 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
cellular amide metabolic process GO:0043603 4 0.013
regulation of macromolecule biosynthetic process GO:0010556 225 0.013
fertilization GO:0009566 3 0.013
meiotic chromosome segregation GO:0045132 3 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
neuron differentiation GO:0030182 353 0.013
neurotransmitter transport GO:0006836 2 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
cellular protein metabolic process GO:0044267 129 0.013
Human Mouse
macromolecule modification GO:0043412 111 0.013
Human Mouse
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
negative regulation of protein complex assembly GO:0031333 1 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
regulation of jak stat cascade GO:0046425 3 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
cell morphogenesis GO:0000902 289 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
cell matrix adhesion GO:0007160 4 0.013
leukocyte proliferation GO:0070661 1 0.013
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.013
response to carbohydrate GO:0009743 3 0.013
erk1 and erk2 cascade GO:0070371 4 0.013
germ line stem cell maintenance GO:0030718 2 0.012
cell substrate adhesion GO:0031589 4 0.012
sensory perception of pain GO:0019233 1 0.012
developmental growth GO:0048589 166 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
camera type eye development GO:0043010 222 0.012
tube morphogenesis GO:0035239 349 0.012
regulation of sequestering of calcium ion GO:0051282 4 0.012
primary neural tube formation GO:0014020 1 0.012
neurotransmitter secretion GO:0007269 2 0.012
cellular protein modification process GO:0006464 100 0.012
Human Mouse
cellular localization GO:0051641 97 0.012
response to unfolded protein GO:0006986 2 0.012
cytoplasm organization GO:0007028 4 0.012
regulation of developmental process GO:0050793 247 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
intracellular signal transduction GO:0035556 85 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
response to organic substance GO:0010033 153 0.012
Mouse
organelle assembly GO:0070925 110 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
generation of neurons GO:0048699 385 0.012
positive regulation of cellular process GO:0048522 201 0.012
negative regulation of sequestering of calcium ion GO:0051283 4 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
lateral inhibition GO:0046331 1 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
regulation of inflammatory response GO:0050727 2 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
nucleic acid transport GO:0050657 2 0.012
regulation of gtpase activity GO:0043087 2 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
neurological system process GO:0050877 62 0.012
multi organism process GO:0051704 134 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
gastrulation GO:0007369 208 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
response to external biotic stimulus GO:0043207 97 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
er nucleus signaling pathway GO:0006984 2 0.011
protein homooligomerization GO:0051260 3 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
post embryonic organ development GO:0048569 4 0.011
neuron development GO:0048666 262 0.011
microtubule organizing center organization GO:0031023 1 0.011
negative regulation of cytokine production GO:0001818 1 0.011
response to monosaccharide GO:0034284 3 0.011
regulation of autophagy GO:0010506 3 0.011
negative regulation of catabolic process GO:0009895 3 0.011
digestive tract development GO:0048565 265 0.011
antimicrobial humoral response GO:0019730 2 0.011
mitochondrial transport GO:0006839 2 0.011
protein modification process GO:0036211 100 0.011
Human Mouse
interspecies interaction between organisms GO:0044419 4 0.011
angiogenesis GO:0001525 158 0.011
regulation of protein complex disassembly GO:0043244 1 0.011
catecholamine metabolic process GO:0006584 2 0.011
cell projection morphogenesis GO:0048858 244 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
b cell activation GO:0042113 2 0.011
nucleobase containing compound transport GO:0015931 2 0.011
macroautophagy GO:0016236 1 0.011
regulation of protein localization to plasma membrane GO:1903076 1 0.011
mononuclear cell proliferation GO:0032943 1 0.011
small molecule catabolic process GO:0044282 3 0.011
muscle cell differentiation GO:0042692 139 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
response to hydrogen peroxide GO:0042542 3 0.011
pole plasm assembly GO:0007315 4 0.011
regulation of dna templated transcription elongation GO:0032784 3 0.011
regulation of dendrite development GO:0050773 3 0.011
dna templated transcription elongation GO:0006354 3 0.011
carbohydrate homeostasis GO:0033500 1 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
regulation of organ growth GO:0046620 3 0.011
regulation of transporter activity GO:0032409 2 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
nuclear export GO:0051168 1 0.011
sensory organ morphogenesis GO:0090596 200 0.011
growth GO:0040007 174 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
regulation of localization GO:0032879 104 0.011
blood vessel morphogenesis GO:0048514 216 0.011
cellular response to light stimulus GO:0071482 4 0.011
regulation of blood pressure GO:0008217 1 0.011
cellular response to unfolded protein GO:0034620 2 0.011
phosphorus metabolic process GO:0006793 109 0.011
response to nutrient GO:0007584 3 0.011
somatic muscle development GO:0007525 4 0.011
endoplasmic reticulum unfolded protein response GO:0030968 2 0.011
spindle assembly GO:0051225 2 0.010
lamellipodium assembly GO:0030032 1 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
chordate embryonic development GO:0043009 271 0.010
regulation of stem cell proliferation GO:0072091 2 0.010
regulation of wound healing GO:0061041 2 0.010
negative regulation of protein transport GO:0051224 3 0.010
cortical actin cytoskeleton organization GO:0030866 1 0.010
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
specification of symmetry GO:0009799 204 0.010
sleep GO:0030431 1 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
regulation of exocytosis GO:0017157 1 0.010
cytosolic calcium ion transport GO:0060401 3 0.010
cellular component assembly involved in morphogenesis GO:0010927 107 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.010
ear development GO:0043583 127 0.010
regulation of programmed cell death GO:0043067 101 0.010
cortical cytoskeleton organization GO:0030865 1 0.010
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.010
lymphocyte proliferation GO:0046651 1 0.010
calcium ion transport into cytosol GO:0060402 3 0.010
regionalization GO:0003002 274 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.010
establishment of rna localization GO:0051236 3 0.010
female meiotic division GO:0007143 2 0.010
muscle cell development GO:0055001 115 0.010
positive regulation of protein complex assembly GO:0031334 2 0.010
female gonad development GO:0008585 4 0.010

ube2w disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.027
disease of metabolism DOID:0014667 0 0.014
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
inherited metabolic disorder DOID:655 0 0.012
musculoskeletal system disease DOID:17 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010