Danio rerio

35 known processes

fam65b

family with sequence similarity 65, member B

(Aliases: si:dkey-218n20.1)

fam65b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
signal transduction GO:0007165 455 0.100
larval development GO:0002164 2 0.095
cell surface receptor signaling pathway GO:0007166 325 0.060
aging GO:0007568 2 0.057
establishment of localization GO:0051234 244 0.055
cellular macromolecule metabolic process GO:0044260 391 0.054
sensory organ development GO:0007423 393 0.054
multicellular organism growth GO:0035264 4 0.047
cellular component movement GO:0006928 335 0.047
nitrogen compound metabolic process GO:0006807 319 0.047
negative regulation of biological process GO:0048519 304 0.045
generation of neurons GO:0048699 385 0.045
positive regulation of transport GO:0051050 2 0.043
cellular biosynthetic process GO:0044249 286 0.043
regulation of synapse organization GO:0050807 3 0.043
neuron differentiation GO:0030182 353 0.043
embryonic organ development GO:0048568 381 0.041
cell projection organization GO:0030030 284 0.041
synaptic growth at neuromuscular junction GO:0051124 2 0.041
embryonic organ morphogenesis GO:0048562 274 0.040
regulation of metabolic process GO:0019222 359 0.040
regulation of response to stimulus GO:0048583 269 0.040
positive regulation of catabolic process GO:0009896 4 0.039
regulation of primary metabolic process GO:0080090 311 0.038
response to stress GO:0006950 263 0.038
stem cell proliferation GO:0072089 4 0.037
regulation of establishment of protein localization GO:0070201 4 0.036
cell morphogenesis GO:0000902 289 0.036
response to chemical GO:0042221 320 0.036
cellular response to external stimulus GO:0071496 2 0.035
membrane fusion GO:0061025 2 0.035
cell migration GO:0016477 237 0.035
regulation of cytoplasmic transport GO:1903649 4 0.035
biosynthetic process GO:0009058 294 0.035
regulation of synapse assembly GO:0051963 3 0.035
neuron projection development GO:0031175 180 0.034
rna metabolic process GO:0016070 219 0.034
single organism transport GO:0044765 206 0.034
organic substance biosynthetic process GO:1901576 289 0.034
organic cyclic compound biosynthetic process GO:1901362 223 0.034
cellular nitrogen compound metabolic process GO:0034641 290 0.034
regulation of cellular metabolic process GO:0031323 320 0.033
aromatic compound biosynthetic process GO:0019438 217 0.033
regulation of macromolecule biosynthetic process GO:0010556 225 0.033
transport GO:0006810 220 0.033
nucleic acid metabolic process GO:0090304 244 0.033
regulation of multicellular organism growth GO:0040014 4 0.033
eye development GO:0001654 277 0.033
regulation of cellular biosynthetic process GO:0031326 245 0.032
gene expression GO:0010467 252 0.032
regulation of cell communication GO:0010646 232 0.032
cell projection morphogenesis GO:0048858 244 0.032
regulation of protein transport GO:0051223 3 0.031
negative regulation of cellular process GO:0048523 283 0.031
macromolecule biosynthetic process GO:0009059 227 0.031
positive regulation of cell cycle GO:0045787 3 0.031
organelle fusion GO:0048284 3 0.031
maintenance of location GO:0051235 4 0.031
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.031
guanosine containing compound metabolic process GO:1901068 4 0.031
guanosine containing compound catabolic process GO:1901069 2 0.030
chordate embryonic development GO:0043009 271 0.030
morphogenesis of an epithelium GO:0002009 333 0.030
regulation of cytokine production GO:0001817 3 0.030
gtp metabolic process GO:0046039 4 0.030
regulation of biological quality GO:0065008 263 0.030
heterocycle metabolic process GO:0046483 290 0.029
gtp catabolic process GO:0006184 2 0.029
tube morphogenesis GO:0035239 349 0.029
nucleobase containing compound metabolic process GO:0006139 274 0.029
regulation of signal transduction GO:0009966 225 0.029
regulation of signaling GO:0023051 235 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
organic cyclic compound metabolic process GO:1901360 301 0.028
camera type eye development GO:0043010 222 0.028
cellular amine metabolic process GO:0044106 2 0.028
cellular component morphogenesis GO:0032989 336 0.028
amine metabolic process GO:0009308 2 0.028
regulation of rna metabolic process GO:0051252 224 0.028
regulation of nucleoside metabolic process GO:0009118 2 0.027
system process GO:0003008 185 0.027
neuroblast proliferation GO:0007405 2 0.027
cytokinesis GO:0000910 3 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
response to external stimulus GO:0009605 264 0.027
localization of cell GO:0051674 244 0.027
single organism membrane fusion GO:0044801 2 0.026
heterocycle biosynthetic process GO:0018130 215 0.026
sensory organ morphogenesis GO:0090596 200 0.026
regulation of binding GO:0051098 3 0.026
regulation of multicellular organismal process GO:0051239 277 0.026
regulation of nucleocytoplasmic transport GO:0046822 2 0.026
embryo development ending in birth or egg hatching GO:0009792 271 0.026
cellular response to extracellular stimulus GO:0031668 2 0.026
blood vessel development GO:0001568 246 0.026
microtubule based movement GO:0007018 33 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
cellular protein catabolic process GO:0044257 4 0.025
phagocytosis GO:0006909 3 0.025
digestive tract morphogenesis GO:0048546 231 0.025
single organism metabolic process GO:0044710 217 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.025
cellular nitrogen compound biosynthetic process GO:0044271 218 0.025
regulation of synaptic plasticity GO:0048167 1 0.024
single organism localization GO:1902578 225 0.024
digestive system development GO:0055123 289 0.024
locomotion GO:0040011 313 0.024
regionalization GO:0003002 274 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
regulation of purine nucleotide catabolic process GO:0033121 2 0.023
regulation of reproductive process GO:2000241 4 0.023
muscle structure development GO:0061061 196 0.023
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
cellular protein modification process GO:0006464 100 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
stem cell division GO:0017145 1 0.023
regulation of biosynthetic process GO:0009889 250 0.023
response to drug GO:0042493 3 0.023
cell motility GO:0048870 244 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
vasculature development GO:0001944 278 0.022
inner ear development GO:0048839 126 0.022
regulation of protein catabolic process GO:0042176 1 0.022
exocytosis GO:0006887 1 0.022
mitochondrion organization GO:0007005 4 0.022
stem cell maintenance GO:0019827 4 0.022
rna biosynthetic process GO:0032774 181 0.022
neuron development GO:0048666 262 0.022
cellular aromatic compound metabolic process GO:0006725 295 0.022
head development GO:0060322 303 0.022
regulation of nucleic acid templated transcription GO:1903506 213 0.022
response to carbohydrate GO:0009743 3 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
cell part morphogenesis GO:0032990 246 0.021
positive regulation of biological process GO:0048518 253 0.021
amino acid transport GO:0006865 2 0.021
protein import into nucleus GO:0006606 3 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
protein targeting to nucleus GO:0044744 3 0.021
axon development GO:0061564 166 0.021
regulation of developmental process GO:0050793 247 0.021
phototransduction GO:0007602 2 0.021
growth GO:0040007 174 0.021
gastrulation GO:0007369 208 0.021
regulation of intracellular protein transport GO:0033157 3 0.021
somatic muscle development GO:0007525 4 0.021
protein metabolic process GO:0019538 183 0.021
regulation of multicellular organismal development GO:2000026 223 0.020
retina development in camera type eye GO:0060041 146 0.020
cellular component disassembly GO:0022411 1 0.020
protein localization to nucleus GO:0034504 3 0.020
skeletal system development GO:0001501 181 0.020
nuclear transport GO:0051169 4 0.020
developmental growth GO:0048589 166 0.020
cellular ketone metabolic process GO:0042180 11 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
blood vessel morphogenesis GO:0048514 216 0.020
transcription dna templated GO:0006351 181 0.020
digestive tract development GO:0048565 265 0.020
muscle cell differentiation GO:0042692 139 0.020
macromolecule modification GO:0043412 111 0.020
cell substrate adhesion GO:0031589 4 0.020
response to monosaccharide GO:0034284 3 0.020
regulation of sequestering of calcium ion GO:0051282 4 0.020
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
cellular response to starvation GO:0009267 1 0.019
establishment of synaptic vesicle localization GO:0097480 1 0.019
adult behavior GO:0030534 2 0.019
response to hexose GO:0009746 3 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.019
oxoacid metabolic process GO:0043436 31 0.019
cellular response to nutrient levels GO:0031669 2 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
regulation of epithelial cell proliferation GO:0050678 3 0.019
immune system process GO:0002376 241 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
regulation of nucleotide catabolic process GO:0030811 2 0.019
neurotransmitter transport GO:0006836 2 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
positive regulation of secretion by cell GO:1903532 1 0.019
carbohydrate homeostasis GO:0033500 1 0.019
negative regulation of protein kinase activity GO:0006469 4 0.019
single organism nuclear import GO:1902593 3 0.019
meiotic nuclear division GO:0007126 4 0.019
modification dependent protein catabolic process GO:0019941 3 0.019
central nervous system development GO:0007417 387 0.019
response to wounding GO:0009611 116 0.019
establishment of protein localization to organelle GO:0072594 4 0.018
regulation of cell shape GO:0008360 1 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
response to biotic stimulus GO:0009607 97 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
regulation of protein complex assembly GO:0043254 3 0.018
regulation of protein targeting GO:1903533 2 0.018
regulation of gene expression GO:0010468 265 0.018
post embryonic organ development GO:0048569 4 0.018
rna localization GO:0006403 4 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.018
positive regulation of secretion GO:0051047 1 0.018
single organism organelle organization GO:1902589 199 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
wnt signaling pathway GO:0016055 80 0.018
lipid storage GO:0019915 1 0.018
cellular response to radiation GO:0071478 4 0.018
small molecule metabolic process GO:0044281 77 0.018
organic acid metabolic process GO:0006082 31 0.018
phosphorus metabolic process GO:0006793 109 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
regulation of metal ion transport GO:0010959 4 0.018
eye morphogenesis GO:0048592 144 0.018
apoptotic process GO:0006915 116 0.017
tissue remodeling GO:0048771 4 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
dicarboxylic acid transport GO:0006835 1 0.017
cognition GO:0050890 1 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
intracellular signal transduction GO:0035556 85 0.017
nucleobase containing compound biosynthetic process GO:0034654 205 0.017
response to glucose GO:0009749 3 0.017
meiotic cell cycle process GO:1903046 3 0.017
protein import GO:0017038 3 0.017
cortical cytoskeleton organization GO:0030865 1 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
purine nucleoside monophosphate catabolic process GO:0009128 4 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
embryonic skeletal system development GO:0048706 97 0.017
germ line stem cell maintenance GO:0030718 2 0.017
cilium morphogenesis GO:0060271 85 0.017
regulation of circadian rhythm GO:0042752 4 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
ear development GO:0043583 127 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
cilium organization GO:0044782 71 0.016
nucleic acid templated transcription GO:0097659 181 0.016
hemopoiesis GO:0030097 183 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
peptidyl serine modification GO:0018209 2 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
compound eye development GO:0048749 2 0.016
determination of bilateral symmetry GO:0009855 204 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.016
glucose homeostasis GO:0042593 1 0.016
brain development GO:0007420 293 0.016
cellular response to light stimulus GO:0071482 4 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
endosomal transport GO:0016197 2 0.016
regulation of gtpase activity GO:0043087 2 0.016
immune system development GO:0002520 191 0.016
neurotransmitter secretion GO:0007269 2 0.016
neuron neuron synaptic transmission GO:0007270 1 0.015
positive regulation of cellular process GO:0048522 201 0.015
cellular protein metabolic process GO:0044267 129 0.015
homeostatic process GO:0042592 142 0.015
cellular component assembly GO:0022607 170 0.015
regulation of cell substrate adhesion GO:0010810 1 0.015
phototransduction visible light GO:0007603 2 0.015
cortical actin cytoskeleton organization GO:0030866 1 0.015
secondary metabolic process GO:0019748 3 0.015
regulation of localization GO:0032879 104 0.015
determination of left right symmetry GO:0007368 179 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
programmed cell death GO:0012501 119 0.015
neurological system process GO:0050877 62 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
regulation of cell activation GO:0050865 1 0.015
regulation of dendrite development GO:0050773 3 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.015
angiogenesis GO:0001525 158 0.015
nuclear import GO:0051170 3 0.015
response to organic substance GO:0010033 153 0.015
organelle organization GO:0006996 227 0.015
negative regulation of kinase activity GO:0033673 4 0.015
protein dephosphorylation GO:0006470 3 0.015
protein modification process GO:0036211 100 0.015
fat soluble vitamin metabolic process GO:0006775 4 0.015
neuron projection morphogenesis GO:0048812 161 0.015
hormone transport GO:0009914 2 0.015
regulation of protein binding GO:0043393 3 0.015
mechanosensory behavior GO:0007638 2 0.015
regulation of cell differentiation GO:0045595 142 0.014
response to external biotic stimulus GO:0043207 97 0.014
wound healing GO:0042060 90 0.014
peptidyl serine phosphorylation GO:0018105 1 0.014
phosphorylation GO:0016310 69 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
positive regulation of cytokine production GO:0001819 2 0.014
lipid catabolic process GO:0016042 4 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
somite development GO:0061053 96 0.014
protein complex disassembly GO:0043241 1 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
regulation of transcription dna templated GO:0006355 213 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
regulation of programmed cell death GO:0043067 101 0.014
anterior posterior pattern specification GO:0009952 152 0.014
regulation of wound healing GO:0061041 2 0.014
atp catabolic process GO:0006200 4 0.014
golgi vesicle transport GO:0048193 3 0.014
response to alkaloid GO:0043279 2 0.014
macromolecular complex disassembly GO:0032984 1 0.014
organism emergence from protective structure GO:0071684 4 0.014
actin filament based movement GO:0030048 1 0.014
cell death GO:0008219 121 0.014
autophagy GO:0006914 4 0.014
antimicrobial humoral response GO:0019730 2 0.014
embryonic cranial skeleton morphogenesis GO:0048701 90 0.014
synaptic vesicle localization GO:0097479 1 0.013
positive regulation of jak stat cascade GO:0046427 2 0.013
synaptic transmission cholinergic GO:0007271 4 0.013
response to corticosteroid GO:0031960 1 0.013
regulation of jak stat cascade GO:0046425 3 0.013
axonogenesis GO:0007409 152 0.013
cellular component biogenesis GO:0044085 178 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
oocyte anterior posterior axis specification GO:0007314 4 0.013
myeloid cell differentiation GO:0030099 86 0.013
negative regulation of cell communication GO:0010648 96 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
embryonic skeletal system morphogenesis GO:0048704 93 0.013
cartilage development GO:0051216 96 0.013
sequestering of metal ion GO:0051238 3 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
adherens junction organization GO:0034332 4 0.013
alcohol biosynthetic process GO:0046165 2 0.013
interspecies interaction between organisms GO:0044419 4 0.013
lateral line development GO:0048882 66 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
sequestering of calcium ion GO:0051208 3 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
negative regulation of signaling GO:0023057 96 0.013
membrane invagination GO:0010324 1 0.012
protein localization to plasma membrane GO:0072659 1 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
developmental growth involved in morphogenesis GO:0060560 86 0.012
stem cell differentiation GO:0048863 117 0.012
somitogenesis GO:0001756 87 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
skeletal system morphogenesis GO:0048705 102 0.012
synaptic vesicle transport GO:0048489 1 0.012
macroautophagy GO:0016236 1 0.012
response to glucocorticoid GO:0051384 1 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
fertilization GO:0009566 3 0.012
connective tissue development GO:0061448 99 0.012
lateral line system development GO:0048925 76 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
chemosensory behavior GO:0007635 1 0.012
multi organism cellular process GO:0044764 2 0.012
tube closure GO:0060606 1 0.012
cytoplasm organization GO:0007028 4 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
positive regulation of signal transduction GO:0009967 56 0.012
sensory system development GO:0048880 76 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
response to other organism GO:0051707 97 0.012
regulation of exocytosis GO:0017157 1 0.012
cellular amide metabolic process GO:0043603 4 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
startle response GO:0001964 4 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
melanin metabolic process GO:0006582 2 0.012
multi organism process GO:0051704 134 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
regulation of apoptotic process GO:0042981 98 0.011
protein secretion GO:0009306 1 0.011
response to hydrogen peroxide GO:0042542 3 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
lateral inhibition GO:0046331 1 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
pigmentation GO:0043473 85 0.011
negative regulation of signal transduction GO:0009968 94 0.011
response to abiotic stimulus GO:0009628 122 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
tyrosine phosphorylation of stat protein GO:0007260 1 0.011
positive regulation of cell division GO:0051781 2 0.011
positive regulation of epithelial cell proliferation GO:0050679 1 0.011
peptidyl threonine phosphorylation GO:0018107 1 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
phagocytosis engulfment GO:0006911 1 0.011
inner ear morphogenesis GO:0042472 63 0.011
calcium mediated signaling GO:0019722 2 0.011
protein phosphorylation GO:0006468 47 0.011
response to uv GO:0009411 3 0.011
cellular localization GO:0051641 97 0.011
camera type eye morphogenesis GO:0048593 108 0.011
regeneration GO:0031099 91 0.011
response to nutrient GO:0007584 3 0.011
peptide transport GO:0015833 1 0.011
glial cell migration GO:0008347 3 0.011
positive regulation of epithelial cell differentiation GO:0030858 2 0.011
regulation of transporter activity GO:0032409 2 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
pole plasm assembly GO:0007315 4 0.011
regulation of organ growth GO:0046620 3 0.011
negative regulation of multi organism process GO:0043901 3 0.011
cell matrix adhesion GO:0007160 4 0.010
detection of stimulus GO:0051606 29 0.010
intracellular mrna localization GO:0008298 1 0.010
regulation of cell death GO:0010941 103 0.010
g protein coupled receptor signaling pathway GO:0007186 74 0.010
protein polymerization GO:0051258 4 0.010
positive regulation of synapse assembly GO:0051965 1 0.010
cellular pigmentation GO:0033059 30 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.010
heart development GO:0007507 313 0.010
ameboidal type cell migration GO:0001667 143 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
sensory perception of chemical stimulus GO:0007606 3 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
regulation of muscle contraction GO:0006937 3 0.010
b cell activation GO:0042113 2 0.010
inositol lipid mediated signaling GO:0048017 2 0.010
ion transport GO:0006811 114 0.010
gland development GO:0048732 143 0.010
negative regulation of intracellular protein transport GO:0090317 3 0.010
regulation of molecular function GO:0065009 70 0.010
response to bacterium GO:0009617 58 0.010
mesenchyme development GO:0060485 127 0.010

fam65b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.022
disease of metabolism DOID:0014667 0 0.014
immune system disease DOID:2914 0 0.013
sensory system disease DOID:0050155 0 0.013
musculoskeletal system disease DOID:17 0 0.012
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011
retinal disease DOID:5679 0 0.010