Danio rerio

0 known processes

nsfb

N-ethylmaleimide-sensitive factor b

nsfb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.108
Worm
single organism localization GO:1902578 225 0.091
Worm Fly
aging GO:0007568 2 0.085
lipid storage GO:0019915 1 0.075
sensory organ development GO:0007423 393 0.073
Zebrafish
single organism transport GO:0044765 206 0.070
Worm Fly
anion transport GO:0006820 38 0.068
ion transport GO:0006811 114 0.063
maintenance of location GO:0051235 4 0.060
neuron neuron synaptic transmission GO:0007270 1 0.060
response to chemical GO:0042221 320 0.059
transmembrane transport GO:0055085 120 0.058
establishment of localization GO:0051234 244 0.057
Worm Fly
regulation of circadian rhythm GO:0042752 4 0.057
phagocytosis GO:0006909 3 0.052
Fly
g protein coupled receptor signaling pathway GO:0007186 74 0.051
endosomal transport GO:0016197 2 0.047
regulation of biological quality GO:0065008 263 0.046
Zebrafish Fly
cellular carbohydrate metabolic process GO:0044262 4 0.046
head development GO:0060322 303 0.043
Zebrafish
startle response GO:0001964 4 0.041
embryonic organ development GO:0048568 381 0.040
multicellular organism growth GO:0035264 4 0.039
transport GO:0006810 220 0.038
Worm Fly
positive regulation of transport GO:0051050 2 0.038
Fly
cellular response to lipopolysaccharide GO:0071222 3 0.037
signal transduction GO:0007165 455 0.037
inorganic anion transport GO:0015698 25 0.037
regulation of synaptic plasticity GO:0048167 1 0.035
Fly
ion transmembrane transport GO:0034220 91 0.035
central nervous system development GO:0007417 387 0.034
Zebrafish
eye development GO:0001654 277 0.034
Zebrafish
stem cell proliferation GO:0072089 4 0.034
nitrogen compound metabolic process GO:0006807 319 0.034
Fly
organelle fusion GO:0048284 3 0.034
Fly
amino acid transport GO:0006865 2 0.033
brain development GO:0007420 293 0.033
Zebrafish
regulation of cytokine production GO:0001817 3 0.032
camera type eye development GO:0043010 222 0.031
locomotion GO:0040011 313 0.031
inorganic cation transmembrane transport GO:0098662 50 0.030
cellular response to external stimulus GO:0071496 2 0.030
single organism membrane fusion GO:0044801 2 0.030
Fly
cell surface receptor signaling pathway GO:0007166 325 0.030
inorganic ion transmembrane transport GO:0098660 57 0.030
negative regulation of biological process GO:0048519 304 0.029
organic anion transport GO:0015711 15 0.029
cellular respiration GO:0045333 3 0.029
response to external stimulus GO:0009605 264 0.029
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.029
Fly
morphogenesis of an epithelium GO:0002009 333 0.029
Fly
cellular response to molecule of bacterial origin GO:0071219 3 0.029
regulation of synapse assembly GO:0051963 3 0.028
Fly
autophagy GO:0006914 4 0.028
positive regulation of cytokine production GO:0001819 2 0.028
response to carbohydrate GO:0009743 3 0.028
system process GO:0003008 185 0.028
Zebrafish
dicarboxylic acid transport GO:0006835 1 0.028
regulation of metal ion transport GO:0010959 4 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
response to drug GO:0042493 3 0.027
synaptic vesicle localization GO:0097479 1 0.026
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.026
Fly
positive regulation of catabolic process GO:0009896 4 0.026
regulation of gene expression GO:0010468 265 0.026
cellular response to biotic stimulus GO:0071216 3 0.025
membrane fusion GO:0061025 2 0.025
Fly
monovalent inorganic cation transport GO:0015672 42 0.025
water transport GO:0006833 15 0.025
lipid catabolic process GO:0016042 4 0.024
positive regulation of secretion by cell GO:1903532 1 0.024
immune system development GO:0002520 191 0.024
stem cell division GO:0017145 1 0.024
actin filament based movement GO:0030048 1 0.024
response to stress GO:0006950 263 0.024
small molecule catabolic process GO:0044282 3 0.024
cellular response to extracellular stimulus GO:0031668 2 0.024
cilium morphogenesis GO:0060271 85 0.023
nucleoside monophosphate catabolic process GO:0009125 4 0.023
Fly
regulation of stem cell proliferation GO:0072091 2 0.023
synaptic vesicle transport GO:0048489 1 0.023
Fly
sensory perception of chemical stimulus GO:0007606 3 0.023
carbon dioxide transport GO:0015670 3 0.023
embryonic organ morphogenesis GO:0048562 274 0.023
regulation of muscle contraction GO:0006937 3 0.023
regulation of synapse organization GO:0050807 3 0.022
Fly
neurological system process GO:0050877 62 0.022
Zebrafish
cell migration GO:0016477 237 0.022
positive regulation of secretion GO:0051047 1 0.022
blood vessel development GO:0001568 246 0.022
response to salt stress GO:0009651 10 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
adult behavior GO:0030534 2 0.022
muscle cell development GO:0055001 115 0.021
Worm
chemosensory behavior GO:0007635 1 0.021
cellular macromolecule metabolic process GO:0044260 391 0.021
cellular response to topologically incorrect protein GO:0035967 2 0.021
heart development GO:0007507 313 0.021
regulation of blood pressure GO:0008217 1 0.021
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.021
cation transmembrane transport GO:0098655 65 0.021
regulation of response to stimulus GO:0048583 269 0.021
cellular response to starvation GO:0009267 1 0.021
carbohydrate homeostasis GO:0033500 1 0.021
regulation of epithelial cell proliferation GO:0050678 3 0.021
sodium ion transmembrane transport GO:0035725 21 0.021
response to monosaccharide GO:0034284 3 0.021
phagocytosis engulfment GO:0006911 1 0.021
positive regulation of myeloid cell differentiation GO:0045639 2 0.020
organic acid metabolic process GO:0006082 31 0.020
hematopoietic or lymphoid organ development GO:0048534 191 0.020
response to alkaloid GO:0043279 2 0.020
response to organic substance GO:0010033 153 0.020
cellular response to nutrient levels GO:0031669 2 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
Fly
neuroblast proliferation GO:0007405 2 0.020
cation transport GO:0006812 81 0.020
glucose homeostasis GO:0042593 1 0.020
one carbon compound transport GO:0019755 14 0.020
neurotransmitter secretion GO:0007269 2 0.020
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
transmission of nerve impulse GO:0019226 19 0.020
Zebrafish
gene expression GO:0010467 252 0.019
hormone transport GO:0009914 2 0.019
modification dependent protein catabolic process GO:0019941 3 0.019
mitochondrion organization GO:0007005 4 0.019
cellular biosynthetic process GO:0044249 286 0.019
cell motility GO:0048870 244 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
gtp catabolic process GO:0006184 2 0.019
cognition GO:0050890 1 0.019
organic cyclic compound metabolic process GO:1901360 301 0.019
Fly
homeostatic process GO:0042592 142 0.019
ribonucleoside monophosphate catabolic process GO:0009158 4 0.019
Fly
proteasomal protein catabolic process GO:0010498 2 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.019
Fly
regulation of tube size GO:0035150 2 0.019
spermatid development GO:0007286 2 0.019
stem cell maintenance GO:0019827 4 0.019
regulation of blood vessel size GO:0050880 2 0.019
regulation of protein complex assembly GO:0043254 3 0.019
neurotransmitter transport GO:0006836 2 0.019
Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.019
response to hexose GO:0009746 3 0.019
regulation of signaling GO:0023051 235 0.019
Fly
gas transport GO:0015669 3 0.019
alcohol biosynthetic process GO:0046165 2 0.018
response to abiotic stimulus GO:0009628 122 0.018
angiogenesis GO:0001525 158 0.018
cellular component disassembly GO:0022411 1 0.018
Fly
positive regulation of stem cell proliferation GO:2000648 1 0.018
response to glucose GO:0009749 3 0.018
mechanosensory behavior GO:0007638 2 0.018
regulation of carbohydrate metabolic process GO:0006109 4 0.018
cell part morphogenesis GO:0032990 246 0.018
Zebrafish
gtp metabolic process GO:0046039 4 0.018
organic substance biosynthetic process GO:1901576 289 0.018
response to topologically incorrect protein GO:0035966 2 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.018
regulation of transmembrane transporter activity GO:0022898 2 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
chordate embryonic development GO:0043009 271 0.017
cytokinesis GO:0000910 3 0.017
regulation of dendrite development GO:0050773 3 0.017
establishment of synaptic vesicle localization GO:0097480 1 0.017
Fly
fertilization GO:0009566 3 0.017
heart morphogenesis GO:0003007 156 0.017
cellular response to oxygen levels GO:0071453 1 0.017
regulation of autophagy GO:0010506 3 0.017
fat soluble vitamin metabolic process GO:0006775 4 0.017
regulation of metabolic process GO:0019222 359 0.017
growth GO:0040007 174 0.017
Fly
regulation of cellular biosynthetic process GO:0031326 245 0.017
somatic muscle development GO:0007525 4 0.016
hormone secretion GO:0046879 2 0.016
digestive tract morphogenesis GO:0048546 231 0.016
atp catabolic process GO:0006200 4 0.016
Fly
negative regulation of catabolic process GO:0009895 3 0.016
neuron differentiation GO:0030182 353 0.016
Zebrafish
entrainment of circadian clock GO:0009649 2 0.016
negative regulation of cellular process GO:0048523 283 0.016
nuclear transport GO:0051169 4 0.016
vasculature development GO:0001944 278 0.016
membrane invagination GO:0010324 1 0.016
regulation of ion transmembrane transporter activity GO:0032412 2 0.016
internal peptidyl lysine acetylation GO:0018393 2 0.016
rna localization GO:0006403 4 0.016
regulation of reactive oxygen species metabolic process GO:2000377 2 0.016
internal protein amino acid acetylation GO:0006475 2 0.016
macroautophagy GO:0016236 1 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.015
Fly
protein acylation GO:0043543 3 0.015
cellular ketone metabolic process GO:0042180 11 0.015
single organism metabolic process GO:0044710 217 0.015
Fly
pigment granule localization GO:0051875 25 0.015
Zebrafish
protein acetylation GO:0006473 2 0.015
biosynthetic process GO:0009058 294 0.015
actin mediated cell contraction GO:0070252 1 0.015
blood vessel morphogenesis GO:0048514 216 0.015
endocrine process GO:0050886 2 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
tube morphogenesis GO:0035239 349 0.015
Fly
spermatid differentiation GO:0048515 2 0.015
regulation of neurological system process GO:0031644 2 0.015
protein secretion GO:0009306 1 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
response to hydrogen peroxide GO:0042542 3 0.015
cellular amine metabolic process GO:0044106 2 0.015
neuromuscular process controlling balance GO:0050885 3 0.015
endoplasmic reticulum unfolded protein response GO:0030968 2 0.015
sleep GO:0030431 1 0.015
regulation of glucose transport GO:0010827 1 0.015
energy reserve metabolic process GO:0006112 2 0.015
chloride transmembrane transport GO:1902476 4 0.015
negative regulation of synapse assembly GO:0051964 2 0.015
oxidation reduction process GO:0055114 41 0.015
regulation of endocrine process GO:0044060 2 0.015
organic substance transport GO:0071702 58 0.015
centrosome organization GO:0051297 1 0.015
regulation of inflammatory response GO:0050727 2 0.015
anion transmembrane transport GO:0098656 12 0.015
regulation of neuronal synaptic plasticity GO:0048168 1 0.014
Fly
cellular component movement GO:0006928 335 0.014
regulation of cell activation GO:0050865 1 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
oxoacid metabolic process GO:0043436 31 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
response to uv GO:0009411 3 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
rna metabolic process GO:0016070 219 0.014
carbohydrate biosynthetic process GO:0016051 1 0.014
multicellular organismal metabolic process GO:0044236 2 0.014
positive regulation of map kinase activity GO:0043406 3 0.014
acylglycerol homeostasis GO:0055090 2 0.014
regulation of primary metabolic process GO:0080090 311 0.014
camera type eye morphogenesis GO:0048593 108 0.014
cellular localization GO:0051641 97 0.014
Zebrafish Worm Fly
regulation of transporter activity GO:0032409 2 0.014
hemopoiesis GO:0030097 183 0.014
glial cell migration GO:0008347 3 0.014
regulation of mrna processing GO:0050684 3 0.014
regulation of protein transport GO:0051223 3 0.014
response to oxygen containing compound GO:1901700 55 0.014
response to biotic stimulus GO:0009607 97 0.014
protein complex disassembly GO:0043241 1 0.014
Fly
macromolecular complex disassembly GO:0032984 1 0.014
Fly
regulation of establishment of protein localization GO:0070201 4 0.014
myeloid cell differentiation GO:0030099 86 0.014
single organism biosynthetic process GO:0044711 71 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
smooth muscle contraction GO:0006939 2 0.013
triglyceride homeostasis GO:0070328 2 0.013
developmental growth GO:0048589 166 0.013
Fly
protein stabilization GO:0050821 2 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
regulation of ph GO:0006885 3 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
regulation of myotube differentiation GO:0010830 2 0.013
regulation of binding GO:0051098 3 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
positive regulation of cell cycle GO:0045787 3 0.013
small molecule metabolic process GO:0044281 77 0.013
Fly
golgi vesicle transport GO:0048193 3 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
regulation of sodium ion transport GO:0002028 2 0.013
regulation of cell communication GO:0010646 232 0.013
Fly
carboxylic acid catabolic process GO:0046395 3 0.013
regulation of hormone secretion GO:0046883 2 0.013
cell matrix adhesion GO:0007160 4 0.013
negative regulation of secretion GO:0051048 2 0.013
meiotic cell cycle process GO:1903046 3 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
female gonad development GO:0008585 4 0.013
response to amphetamine GO:0001975 1 0.013
reactive oxygen species biosynthetic process GO:1903409 1 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
regulation of reproductive process GO:2000241 4 0.013
circadian sleep wake cycle sleep GO:0050802 1 0.013
cellular protein catabolic process GO:0044257 4 0.013
forebrain development GO:0030900 96 0.013
Zebrafish
intracellular mrna localization GO:0008298 1 0.012
actin filament polymerization GO:0030041 2 0.012
vesicle localization GO:0051648 27 0.012
Zebrafish Fly
urea transport GO:0015840 11 0.012
muscle fiber development GO:0048747 52 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
regulation of biosynthetic process GO:0009889 250 0.012
cellular aromatic compound metabolic process GO:0006725 295 0.012
Fly
regulation of glucose import GO:0046324 1 0.012
sensory organ morphogenesis GO:0090596 200 0.012
Zebrafish
protein homooligomerization GO:0051260 3 0.012
Fly
cellular pigmentation GO:0033059 30 0.012
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.012
Fly
positive regulation of epithelial cell proliferation GO:0050679 1 0.012
digestive tract development GO:0048565 265 0.012
regulation of neurotransmitter secretion GO:0046928 1 0.012
hydrogen peroxide metabolic process GO:0042743 2 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
negative regulation of metabolic process GO:0009892 86 0.012
response to unfolded protein GO:0006986 2 0.012
regulation of calcium ion transport GO:0051924 2 0.012
toxin transport GO:1901998 2 0.012
digestive system development GO:0055123 289 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
rna 3 end processing GO:0031123 2 0.012
generation of neurons GO:0048699 385 0.012
Zebrafish
protein import into nucleus GO:0006606 3 0.012
sodium ion transport GO:0006814 24 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
organelle localization GO:0051640 49 0.012
Zebrafish Fly
establishment of localization in cell GO:0051649 77 0.012
Worm Fly
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
Worm
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
exocytosis GO:0006887 1 0.012
Fly
cellular response to reactive oxygen species GO:0034614 2 0.012
cellular transition metal ion homeostasis GO:0046916 3 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
vacuolar transport GO:0007034 2 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
Worm
amine metabolic process GO:0009308 2 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
secondary metabolic process GO:0019748 3 0.012
positive regulation of notch signaling pathway GO:0045747 3 0.012
cell cell signaling GO:0007267 52 0.012
Fly
localization of cell GO:0051674 244 0.012
neuron development GO:0048666 262 0.012
Zebrafish
development of primary female sexual characteristics GO:0046545 4 0.012
homeostasis of number of cells within a tissue GO:0048873 4 0.012
toll like receptor signaling pathway GO:0002224 4 0.012
cellular response to unfolded protein GO:0034620 2 0.012
retina development in camera type eye GO:0060041 146 0.012
immune system process GO:0002376 241 0.012
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.012
endocrine hormone secretion GO:0060986 2 0.012
regulation of response to nutrient levels GO:0032107 1 0.012
response to vitamin GO:0033273 3 0.011
synaptic transmission GO:0007268 35 0.011
Fly
lateral line system development GO:0048925 76 0.011
Zebrafish
response to xenobiotic stimulus GO:0009410 45 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
embryonic limb morphogenesis GO:0030326 2 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
stem cell fate commitment GO:0048865 1 0.011
cellular response to organic substance GO:0071310 105 0.011
fatty acid transport GO:0015908 1 0.011
regulation of endothelial cell proliferation GO:0001936 1 0.011
regulation of postsynaptic membrane potential GO:0060078 1 0.011
positive regulation of carbohydrate metabolic process GO:0045913 1 0.011
wound healing GO:0042060 90 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
organic acid catabolic process GO:0016054 3 0.011
striated muscle cell differentiation GO:0051146 129 0.011
Worm
guanosine containing compound catabolic process GO:1901069 2 0.011
protein localization to plasma membrane GO:0072659 1 0.011
lateral line development GO:0048882 66 0.011
regulation of signal transduction GO:0009966 225 0.011
locomotor rhythm GO:0045475 3 0.011
inorganic anion transmembrane transport GO:0098661 10 0.011
protein import GO:0017038 3 0.011
purine ribonucleoside biosynthetic process GO:0046129 2 0.011
determination of left right symmetry GO:0007368 179 0.011
multicellular organismal macromolecule metabolic process GO:0044259 2 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
metal ion transport GO:0030001 58 0.011
detection of chemical stimulus GO:0009593 4 0.011
positive regulation of endothelial cell proliferation GO:0001938 1 0.011
response to amino acid GO:0043200 2 0.011
ear development GO:0043583 127 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
protein targeting to membrane GO:0006612 1 0.011
nucleic acid metabolic process GO:0090304 244 0.011
regulation of sodium ion transmembrane transport GO:1902305 1 0.011
somatic stem cell maintenance GO:0035019 1 0.011
cell morphogenesis GO:0000902 289 0.011
Zebrafish
multicellular organismal signaling GO:0035637 22 0.011
Zebrafish
meiotic nuclear division GO:0007126 4 0.011
negative regulation of protein transport GO:0051224 3 0.011
protein localization to nucleus GO:0034504 3 0.011
glucose import GO:0046323 2 0.011
axonogenesis GO:0007409 152 0.011
Zebrafish
nucleic acid transport GO:0050657 2 0.011
single fertilization GO:0007338 3 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
erythrocyte differentiation GO:0030218 54 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
peptidyl serine modification GO:0018209 2 0.011
regulation of multicellular organismal metabolic process GO:0044246 2 0.011
organonitrogen compound metabolic process GO:1901564 74 0.011
Fly
cell aging GO:0007569 2 0.010
multicellular organismal response to stress GO:0033555 2 0.010
regulation of carbohydrate biosynthetic process GO:0043255 1 0.010
central nervous system myelination GO:0022010 2 0.010
regulation of gtpase activity GO:0043087 2 0.010
embryonic skeletal system development GO:0048706 97 0.010
leukocyte proliferation GO:0070661 1 0.010
compound eye development GO:0048749 2 0.010
gland development GO:0048732 143 0.010
negative regulation of protein complex assembly GO:0031333 1 0.010
alpha amino acid metabolic process GO:1901605 3 0.010
central nervous system neuron differentiation GO:0021953 74 0.010
Zebrafish
sensory perception of pain GO:0019233 1 0.010
gastrulation GO:0007369 208 0.010
regulation of cell shape GO:0008360 1 0.010
organic acid transport GO:0015849 9 0.010
heterocycle metabolic process GO:0046483 290 0.010
Fly
cell projection organization GO:0030030 284 0.010
Zebrafish
somatic cell dna recombination GO:0016444 1 0.010
regulation of protein catabolic process GO:0042176 1 0.010
interspecies interaction between organisms GO:0044419 4 0.010
protein dephosphorylation GO:0006470 3 0.010
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.010

nsfb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.020
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.018
disease of cellular proliferation DOID:14566 0 0.011