Danio rerio

112 known processes

map2k4a

mitogen-activated protein kinase kinase 4a

(Aliases: MGC136500,MKK4A-l,zgc:136500,MKK4,map2k4)

map2k4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
convergent extension involved in gastrulation GO:0060027 71 0.875
convergent extension GO:0060026 118 0.819
determination of dorsal ventral asymmetry GO:0048262 34 0.632
thrombocyte differentiation GO:0002574 4 0.525
hindbrain development GO:0030902 91 0.523
cell migration involved in gastrulation GO:0042074 79 0.499
nitrogen compound metabolic process GO:0006807 319 0.454
Rat
determination of dorsal identity GO:0048263 13 0.451
morphogenesis of an epithelium GO:0002009 333 0.442
negative regulation of cell cycle GO:0045786 14 0.434
cellular component movement GO:0006928 335 0.433
specification of symmetry GO:0009799 204 0.431
larval development GO:0002164 2 0.430
dorsal convergence GO:0060030 14 0.429
determination of bilateral symmetry GO:0009855 204 0.422
anterior head development GO:0097065 2 0.413
heterocycle metabolic process GO:0046483 290 0.398
Rat
establishment of spindle orientation GO:0051294 10 0.376
anterior posterior pattern specification GO:0009952 152 0.376
Zebrafish
negative regulation of cell cycle process GO:0010948 9 0.371
spindle localization GO:0051653 12 0.367
nucleic acid metabolic process GO:0090304 244 0.349
Rat
blood vessel morphogenesis GO:0048514 216 0.346
cellular macromolecule metabolic process GO:0044260 391 0.339
ectodermal placode morphogenesis GO:0071697 32 0.338
cell cycle GO:0007049 93 0.323
digestive system development GO:0055123 289 0.319
determination of left right symmetry GO:0007368 179 0.314
spinal cord development GO:0021510 46 0.312
embryonic camera type eye development GO:0031076 29 0.311
cellular nitrogen compound metabolic process GO:0034641 290 0.310
Rat
tube morphogenesis GO:0035239 349 0.293
microtubule based process GO:0007017 60 0.289
nucleobase containing compound metabolic process GO:0006139 274 0.284
Rat
brain development GO:0007420 293 0.278
organic cyclic compound metabolic process GO:1901360 301 0.273
Rat
dorsal ventral pattern formation GO:0009953 125 0.272
aging GO:0007568 2 0.271
mitotic cell cycle process GO:1903047 48 0.268
macromolecule biosynthetic process GO:0009059 227 0.268
Rat
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.266
cell surface receptor signaling pathway GO:0007166 325 0.264
determination of heart left right asymmetry GO:0061371 117 0.262
hepaticobiliary system development GO:0061008 98 0.256
cellular aromatic compound metabolic process GO:0006725 295 0.246
Rat
mitotic cell cycle GO:0000278 64 0.246
establishment of cell polarity GO:0030010 18 0.242
cell morphogenesis GO:0000902 289 0.235
Fly
central nervous system neuron differentiation GO:0021953 74 0.233
optic placode formation involved in camera type eye formation GO:0046619 3 0.229
skeletal system development GO:0001501 181 0.228
regulation of primary metabolic process GO:0080090 311 0.227
chordate embryonic development GO:0043009 271 0.227
Zebrafish
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.227
organic cyclic compound biosynthetic process GO:1901362 223 0.224
sensory organ morphogenesis GO:0090596 200 0.223
generation of neurons GO:0048699 385 0.222
Fly
gastrulation GO:0007369 208 0.222
otic vesicle formation GO:0030916 27 0.219
protein metabolic process GO:0019538 183 0.219
ear morphogenesis GO:0042471 64 0.215
response to stress GO:0006950 263 0.215
organelle organization GO:0006996 227 0.214
positive regulation of striated muscle tissue development GO:0045844 1 0.214
cell projection morphogenesis GO:0048858 244 0.214
Fly
cartilage development GO:0051216 96 0.213
hematopoietic or lymphoid organ development GO:0048534 191 0.212
ameboidal type cell migration GO:0001667 143 0.208
central nervous system development GO:0007417 387 0.208
mesodermal cell migration GO:0008078 12 0.208
pancreas development GO:0031016 84 0.208
pectoral fin development GO:0033339 50 0.206
sensory organ development GO:0007423 393 0.205
optic placode formation GO:0001743 4 0.205
gene expression GO:0010467 252 0.204
Worm
camera type eye development GO:0043010 222 0.202
meiotic nuclear division GO:0007126 4 0.201
spinal cord anterior posterior patterning GO:0021512 1 0.199
macromolecule modification GO:0043412 111 0.198
otic vesicle morphogenesis GO:0071600 34 0.198
positive regulation of cellular biosynthetic process GO:0031328 68 0.197
Rat
nucleic acid templated transcription GO:0097659 181 0.194
aromatic compound biosynthetic process GO:0019438 217 0.191
stem cell differentiation GO:0048863 117 0.190
organic substance biosynthetic process GO:1901576 289 0.190
Rat
regulation of signal transduction GO:0009966 225 0.189
negative regulation of sequestering of calcium ion GO:0051283 4 0.189
mitotic nuclear division GO:0007067 18 0.178
embryonic heart tube development GO:0035050 133 0.177
wnt signaling pathway GO:0016055 80 0.174
single organism organelle organization GO:1902589 199 0.174
regulation of transcription dna templated GO:0006355 213 0.174
hepatocyte proliferation GO:0072574 2 0.173
regulation of cell cycle GO:0051726 52 0.170
regulation of developmental process GO:0050793 247 0.170
Fly
immune system development GO:0002520 191 0.170
ventricular system development GO:0021591 12 0.170
rna metabolic process GO:0016070 219 0.169
embryo development ending in birth or egg hatching GO:0009792 271 0.168
Zebrafish
transcription dna templated GO:0006351 181 0.166
cell projection organization GO:0030030 284 0.166
Fly
gastrulation with mouth forming second GO:0001702 44 0.165
mediolateral intercalation GO:0060031 3 0.165
regulation of nitrogen compound metabolic process GO:0051171 251 0.165
Rat
segmentation GO:0035282 97 0.164
Zebrafish
growth GO:0040007 174 0.163
Rat
establishment or maintenance of cell polarity GO:0007163 29 0.160
otic vesicle development GO:0071599 42 0.158
forebrain generation of neurons GO:0021872 14 0.157
camera type eye morphogenesis GO:0048593 108 0.157
modification dependent protein catabolic process GO:0019941 3 0.155
ectodermal placode development GO:0071696 37 0.155
dorsal ventral axis specification GO:0009950 14 0.154
establishment of mitotic spindle orientation GO:0000132 10 0.153
blood vessel development GO:0001568 246 0.151
somitogenesis GO:0001756 87 0.150
Zebrafish
regionalization GO:0003002 274 0.150
regulation of cell growth GO:0001558 29 0.149
single organism metabolic process GO:0044710 217 0.149
forebrain development GO:0030900 96 0.146
regulation of multicellular organism growth GO:0040014 4 0.145
ubiquitin dependent protein catabolic process GO:0006511 3 0.145
regulation of macromolecule biosynthetic process GO:0010556 225 0.145
Rat
neuron projection morphogenesis GO:0048812 161 0.143
Fly
embryonic eye morphogenesis GO:0048048 30 0.141
ear development GO:0043583 127 0.141
negative regulation of cellular process GO:0048523 283 0.140
metencephalon development GO:0022037 27 0.140
ectodermal placode formation GO:0060788 26 0.139
positive regulation of catabolic process GO:0009896 4 0.139
regulation of protein import into nucleus GO:0042306 2 0.138
eye morphogenesis GO:0048592 144 0.138
epithalamus development GO:0021538 10 0.138
regulation of gene expression GO:0010468 265 0.137
Worm
heterocycle biosynthetic process GO:0018130 215 0.137
digestive tract development GO:0048565 265 0.136
vasculature development GO:0001944 278 0.134
cell migration GO:0016477 237 0.133
striated muscle tissue development GO:0014706 110 0.131
Rat
hemopoiesis GO:0030097 183 0.131
negative regulation of wnt signaling pathway GO:0030178 30 0.130
heart development GO:0007507 313 0.130
Rat
response to external stimulus GO:0009605 264 0.128
Human
cellular biosynthetic process GO:0044249 286 0.127
Rat
axonogenesis GO:0007409 152 0.127
establishment of spindle localization GO:0051293 12 0.127
hypothalamus development GO:0021854 14 0.124
adherens junction organization GO:0034332 4 0.124
negative regulation of biological process GO:0048519 304 0.122
Worm
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.122
stem cell proliferation GO:0072089 4 0.122
programmed cell death GO:0012501 119 0.121
Rat
cytoskeleton organization GO:0007010 96 0.120
homeostatic process GO:0042592 142 0.120
cellular protein metabolic process GO:0044267 129 0.120
regulation of cellular biosynthetic process GO:0031326 245 0.120
Rat
diencephalon development GO:0021536 58 0.120
regulation of multicellular organismal development GO:2000026 223 0.118
Fly
organelle localization GO:0051640 49 0.117
positive regulation of cellular process GO:0048522 201 0.117
cell motility GO:0048870 244 0.116
locomotion GO:0040011 313 0.116
regulation of multicellular organismal process GO:0051239 277 0.116
Fly
hepatic duct development GO:0061011 2 0.114
positive regulation of macromolecule metabolic process GO:0010604 93 0.114
regulation of canonical wnt signaling pathway GO:0060828 34 0.114
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.114
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.112
post anal tail morphogenesis GO:0036342 19 0.111
localization of cell GO:0051674 244 0.111
regulation of biological quality GO:0065008 263 0.111
Worm
gall bladder development GO:0061010 1 0.111
regulation of rna biosynthetic process GO:2001141 213 0.110
developmental growth involved in morphogenesis GO:0060560 86 0.110
negative regulation of nuclear division GO:0051784 3 0.109
regulation of proteolysis GO:0030162 24 0.109
regulation of embryonic development GO:0045995 47 0.109
fin regeneration GO:0031101 51 0.108
regulation of metabolic process GO:0019222 359 0.108
maintenance of location GO:0051235 4 0.108
nuclear transport GO:0051169 4 0.108
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.107
axon guidance GO:0007411 86 0.107
neuron differentiation GO:0030182 353 0.107
Fly
endoderm development GO:0007492 49 0.106
cellular nitrogen compound biosynthetic process GO:0044271 218 0.106
cellular macromolecule biosynthetic process GO:0034645 224 0.106
Rat
regulation of axon extension GO:0030516 24 0.105
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.104
ectoderm development GO:0007398 9 0.103
regulation of cellular metabolic process GO:0031323 320 0.103
cell part morphogenesis GO:0032990 246 0.103
Fly
angiogenesis GO:0001525 158 0.102
regulation of rna metabolic process GO:0051252 224 0.101
cellular response to chemical stimulus GO:0070887 157 0.101
Rat
liver development GO:0001889 96 0.101
liver morphogenesis GO:0072576 8 0.101
negative regulation of signal transduction GO:0009968 94 0.101
neuron projection extension GO:1990138 45 0.100
taxis GO:0042330 109 0.100
developmental growth GO:0048589 166 0.099
Rat
limbic system development GO:0021761 16 0.098
spemann organizer formation GO:0060061 10 0.097
embryonic camera type eye formation GO:0060900 10 0.097
negative regulation of cell communication GO:0010648 96 0.097
notochord development GO:0030903 54 0.096
regulation of cysteine type endopeptidase activity GO:2000116 21 0.095
heart looping GO:0001947 94 0.092
positive regulation of cell communication GO:0010647 56 0.091
positive regulation of cellular catabolic process GO:0031331 3 0.091
single organism localization GO:1902578 225 0.090
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.089
swim bladder development GO:0048794 19 0.089
muscle tissue development GO:0060537 110 0.088
Rat
tissue regeneration GO:0042246 74 0.088
inner ear development GO:0048839 126 0.088
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.088
embryonic organ morphogenesis GO:0048562 274 0.088
organelle fission GO:0048285 23 0.087
nuclear division GO:0000280 23 0.086
multicellular organism growth GO:0035264 4 0.086
microtubule cytoskeleton organization GO:0000226 33 0.086
negative regulation of response to stimulus GO:0048585 104 0.086
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.085
retina development in camera type eye GO:0060041 146 0.085
regulation of synapse organization GO:0050807 3 0.085
Worm
extrinsic apoptotic signaling pathway GO:0097191 3 0.085
pronuclear migration GO:0035046 1 0.085
regulation of anterior head development GO:2000742 2 0.084
cell death GO:0008219 121 0.083
Rat
embryonic pattern specification GO:0009880 44 0.083
negative regulation of signaling GO:0023057 96 0.083
immune system process GO:0002376 241 0.083
connective tissue development GO:0061448 99 0.083
nucleocytoplasmic transport GO:0006913 4 0.082
cell fate commitment GO:0045165 99 0.081
establishment of localization GO:0051234 244 0.081
rna biosynthetic process GO:0032774 181 0.081
regulation of signaling GO:0023051 235 0.080
locus ceruleus development GO:0021703 3 0.080
regulation of cellular response to growth factor stimulus GO:0090287 35 0.079
regulation of bmp signaling pathway GO:0030510 39 0.079
protein complex subunit organization GO:0071822 46 0.078
cell growth GO:0016049 57 0.078
Rat
regulation of protein catabolic process GO:0042176 1 0.077
protein import GO:0017038 3 0.077
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.077
Rat
microtubule organizing center organization GO:0031023 1 0.076
negative regulation of mitotic cell cycle GO:0045930 11 0.076
stem cell development GO:0048864 82 0.076
cellular response to nutrient levels GO:0031669 2 0.075
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.075
regulation of intracellular protein transport GO:0033157 3 0.074
negative regulation of mitosis GO:0045839 3 0.074
regulation of organ growth GO:0046620 3 0.073
odontogenesis of dentin containing tooth GO:0042475 1 0.073
negative regulation of catabolic process GO:0009895 3 0.072
protein targeting to nucleus GO:0044744 3 0.072
regeneration GO:0031099 91 0.071
embryonic organ development GO:0048568 381 0.071
cellular response to external stimulus GO:0071496 2 0.071
Human
fourth ventricle development GO:0021592 8 0.071
developmental induction GO:0031128 10 0.070
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.070
regulation of cytokine production GO:0001817 3 0.069
regulation of cell cycle process GO:0010564 20 0.068
otic placode formation GO:0043049 23 0.068
establishment of mitotic spindle localization GO:0040001 12 0.068
nuclear import GO:0051170 3 0.068
embryonic cranial skeleton morphogenesis GO:0048701 90 0.067
wound healing GO:0042060 90 0.067
regulation of protein transport GO:0051223 3 0.067
pharyngeal system development GO:0060037 18 0.067
thalamus development GO:0021794 6 0.066
regulation of oocyte development GO:0060281 3 0.066
phosphorylation GO:0016310 69 0.065
cellular protein catabolic process GO:0044257 4 0.065
cellular component biogenesis GO:0044085 178 0.064
striated muscle cell differentiation GO:0051146 129 0.064
Rat
divalent inorganic cation homeostasis GO:0072507 22 0.064
kupffer s vesicle development GO:0070121 50 0.064
eye development GO:0001654 277 0.064
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.063
positive regulation of map kinase activity GO:0043406 3 0.063
regulation of cell development GO:0060284 100 0.063
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.063
biosynthetic process GO:0009058 294 0.062
Rat
regulation of anatomical structure morphogenesis GO:0022603 130 0.062
cellular protein modification process GO:0006464 100 0.062
positive regulation of oocyte development GO:0060282 1 0.061
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.061
interaction with host GO:0051701 4 0.061
protein localization to nucleus GO:0034504 3 0.060
regulation of biosynthetic process GO:0009889 250 0.060
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.060
regulation of carbohydrate metabolic process GO:0006109 4 0.060
epithelial tube morphogenesis GO:0060562 148 0.060
meiotic cell cycle process GO:1903046 3 0.059
negative regulation of developmental process GO:0051093 65 0.059
enzyme linked receptor protein signaling pathway GO:0007167 106 0.059
maintenance of cell polarity GO:0030011 5 0.059
guanosine containing compound metabolic process GO:1901068 4 0.059
signal transduction GO:0007165 455 0.059
modification dependent macromolecule catabolic process GO:0043632 3 0.058
canonical wnt signaling pathway GO:0060070 48 0.058
cellular component morphogenesis GO:0032989 336 0.058
Fly
inner ear morphogenesis GO:0042472 63 0.057
cell differentiation in spinal cord GO:0021515 40 0.056
specification of organ identity GO:0010092 2 0.056
centrosome organization GO:0051297 1 0.056
positive regulation of cell cycle GO:0045787 3 0.056
axon development GO:0061564 166 0.056
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.056
Rat
cell morphogenesis involved in differentiation GO:0000904 195 0.055
regulation of anatomical structure size GO:0090066 33 0.055
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.055
establishment of organelle localization GO:0051656 45 0.055
single organism nuclear import GO:1902593 3 0.055
neural plate pattern specification GO:0060896 12 0.055
endocrine pancreas development GO:0031018 27 0.055
response to lipid GO:0033993 60 0.054
mesenchymal cell development GO:0014031 78 0.054
muscle structure development GO:0061061 196 0.054
Rat
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.054
negative regulation of peptidase activity GO:0010466 10 0.054
cellular response to extracellular stimulus GO:0031668 2 0.053
nephron morphogenesis GO:0072028 2 0.053
negative regulation of protein phosphorylation GO:0001933 4 0.053
energy reserve metabolic process GO:0006112 2 0.052
regulation of protein targeting GO:1903533 2 0.052
positive regulation of notch signaling pathway GO:0045747 3 0.052
negative regulation of cytoplasmic transport GO:1903650 2 0.051
stem cell division GO:0017145 1 0.050
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.050
muscle cell differentiation GO:0042692 139 0.050
Rat
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.049
regulation of peptidase activity GO:0052547 23 0.049
protein import into nucleus GO:0006606 3 0.049
axis elongation GO:0003401 31 0.049
peptidyl serine phosphorylation GO:0018105 1 0.049
regulation of skeletal muscle tissue development GO:0048641 4 0.048
regulation of reproductive process GO:2000241 4 0.048
pectoral fin morphogenesis GO:0035138 29 0.048
regulation of nucleic acid templated transcription GO:1903506 213 0.048
positive regulation of muscle tissue development GO:1901863 1 0.047
regulation of apoptotic process GO:0042981 98 0.047
Rat
regulation of wnt signaling pathway GO:0030111 53 0.046
regulation of mitotic cell cycle GO:0007346 25 0.046
embryonic limb morphogenesis GO:0030326 2 0.046
appendage development GO:0048736 80 0.046
regulation of endopeptidase activity GO:0052548 23 0.046
cerebellum development GO:0021549 17 0.046
regulation of axonogenesis GO:0050770 32 0.046
stem cell maintenance GO:0019827 4 0.046
development of primary female sexual characteristics GO:0046545 4 0.046
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.046
neuron projection development GO:0031175 180 0.045
Fly
regulation of nuclear division GO:0051783 9 0.045
neural tube development GO:0021915 62 0.045
regulation of organ morphogenesis GO:2000027 35 0.045
cellular carbohydrate metabolic process GO:0044262 4 0.045
heart morphogenesis GO:0003007 156 0.044
embryonic heart tube morphogenesis GO:0003143 108 0.044
cardiac atrium morphogenesis GO:0003209 2 0.044
oocyte differentiation GO:0009994 14 0.044
axon extension GO:0048675 45 0.043
vasculogenesis GO:0001570 41 0.043
rostrocaudal neural tube patterning GO:0021903 29 0.043
regulation of cell size GO:0008361 29 0.043
regulation of cell maturation GO:1903429 1 0.043
regulation of macromolecule metabolic process GO:0060255 317 0.043
digestive tract morphogenesis GO:0048546 231 0.042
positive regulation of signaling GO:0023056 56 0.042
positive regulation of biological process GO:0048518 253 0.042
head development GO:0060322 303 0.042
convergent extension involved in organogenesis GO:0060029 10 0.042
positive regulation of nucleic acid templated transcription GO:1903508 57 0.042
positive regulation of response to stimulus GO:0048584 80 0.041
embryonic neurocranium morphogenesis GO:0048702 15 0.041
cardiac muscle tissue development GO:0048738 48 0.041
Rat
single organism cell adhesion GO:0098602 29 0.041
unidimensional cell growth GO:0009826 5 0.041
multi organism process GO:0051704 134 0.041
response to chemical GO:0042221 320 0.041
Rat
positive regulation of signal transduction GO:0009967 56 0.041
gland development GO:0048732 143 0.041
neuromast development GO:0048884 46 0.040
convergent extension involved in axis elongation GO:0060028 26 0.040
proteolysis GO:0006508 38 0.040
regulation of meiotic cell cycle GO:0051445 1 0.039
intracellular transport GO:0046907 32 0.039
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.039
positive regulation of cellular metabolic process GO:0031325 94 0.039
regulation of mrna processing GO:0050684 3 0.039
autophagy GO:0006914 4 0.039
ventral spinal cord development GO:0021517 35 0.038
positive regulation of muscle organ development GO:0048636 1 0.038
positive regulation of rna biosynthetic process GO:1902680 57 0.038
regulation of cell matrix adhesion GO:0001952 1 0.038
retina morphogenesis in camera type eye GO:0060042 79 0.038
regulation of programmed cell death GO:0043067 101 0.038
Rat
regulation of reactive oxygen species metabolic process GO:2000377 2 0.038
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.038
Rat
protein modification process GO:0036211 100 0.038
cell cycle process GO:0022402 53 0.038
proteasomal protein catabolic process GO:0010498 2 0.037
cellular localization GO:0051641 97 0.037
negative regulation of cellular catabolic process GO:0031330 3 0.037
release of sequestered calcium ion into cytosol GO:0051209 3 0.037
centrosome cycle GO:0007098 1 0.037
response to nutrient levels GO:0031667 10 0.036
somite development GO:0061053 96 0.036
Zebrafish
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.036
Rat
single organism cellular localization GO:1902580 46 0.036
embryonic pectoral fin morphogenesis GO:0035118 24 0.036
response to wounding GO:0009611 116 0.036
positive regulation of cellular component biogenesis GO:0044089 3 0.036
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.036
cellular component assembly GO:0022607 170 0.035
protein stabilization GO:0050821 2 0.035
regulation of neuron differentiation GO:0045664 56 0.035
regulation of cell death GO:0010941 103 0.035
Rat
death GO:0016265 121 0.035
Rat
cellular response to endogenous stimulus GO:0071495 68 0.035
smad protein complex assembly GO:0007183 1 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.035
Rat
endocrine system development GO:0035270 65 0.035
bmp signaling pathway GO:0030509 52 0.035
sensory epithelium regeneration GO:0070654 14 0.035
regulation of cellular component organization GO:0051128 86 0.035
Worm
neuron projection guidance GO:0097485 86 0.035
common bile duct development GO:0061009 13 0.035
post embryonic organ development GO:0048569 4 0.035
system process GO:0003008 185 0.035
Rat
regulation of mitosis GO:0007088 9 0.035
regulation of response to stimulus GO:0048583 269 0.034
establishment of localization in cell GO:0051649 77 0.034
oocyte maturation GO:0001556 4 0.034
morphogenesis of embryonic epithelium GO:0016331 30 0.034
regulation of stem cell differentiation GO:2000736 4 0.034
gtp metabolic process GO:0046039 4 0.034
developmental process involved in reproduction GO:0003006 27 0.034
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.034
embryonic camera type eye morphogenesis GO:0048596 19 0.034
cellular response to organic substance GO:0071310 105 0.034
Rat
regulation of cell differentiation GO:0045595 142 0.034
myotube differentiation GO:0014902 45 0.034
response to organic substance GO:0010033 153 0.034
Rat
regulation of cell fate commitment GO:0010453 22 0.033
synaptic growth at neuromuscular junction GO:0051124 2 0.033
response to uv GO:0009411 3 0.033
meiotic chromosome segregation GO:0045132 3 0.033
regulation of molecular function GO:0065009 70 0.032
muscle organ development GO:0007517 101 0.032
brain segmentation GO:0035284 6 0.032
catabolic process GO:0009056 32 0.032
positive regulation of gene expression GO:0010628 71 0.032
mesenchymal cell differentiation GO:0048762 87 0.032
positive regulation of metabolic process GO:0009893 108 0.032
apoptotic process GO:0006915 116 0.032
Rat
phosphorus metabolic process GO:0006793 109 0.031
regulation of nucleocytoplasmic transport GO:0046822 2 0.031
peptidyl serine modification GO:0018209 2 0.031
neural plate regionalization GO:0060897 10 0.031
regulation of growth GO:0040008 42 0.031
organelle assembly GO:0070925 110 0.031
female gamete generation GO:0007292 14 0.031
mesenchyme development GO:0060485 127 0.031
mesoderm development GO:0007498 88 0.031
regulation of cell communication GO:0010646 232 0.031
positive regulation of transcription dna templated GO:0045893 57 0.030
fin development GO:0033333 77 0.030
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.030
lateral line system development GO:0048925 76 0.030
forebrain neuron differentiation GO:0021879 14 0.030
otolith development GO:0048840 32 0.030
positive regulation of transport GO:0051050 2 0.030
myeloid cell differentiation GO:0030099 86 0.030
regulation of circadian sleep wake cycle GO:0042749 1 0.030
cell adhesion GO:0007155 40 0.030
heart formation GO:0060914 13 0.030
somatic muscle development GO:0007525 4 0.029
single organism transport GO:0044765 206 0.029
glucose import GO:0046323 2 0.029
negative regulation of cellular component organization GO:0051129 16 0.029
regulation of cellular protein catabolic process GO:1903362 1 0.029
epithelium regeneration GO:1990399 14 0.029
mesenchymal cell proliferation GO:0010463 1 0.029
multi organism reproductive process GO:0044703 36 0.029
positive regulation of epithelial cell differentiation GO:0030858 2 0.029
neural plate anterior posterior regionalization GO:0021999 8 0.028
positive regulation of multicellular organismal process GO:0051240 52 0.028
erythrocyte maturation GO:0043249 8 0.028
mesoderm formation GO:0001707 43 0.028
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.028
negative regulation of apoptotic process GO:0043066 55 0.028

map2k4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.071