Danio rerio

0 known processes

wdfy2

WD repeat and FYVE domain containing 2

(Aliases: zgc:109708,MGC109708,im:7144335)

wdfy2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.119
aging GO:0007568 2 0.059
cellular biosynthetic process GO:0044249 286 0.042
maintenance of location GO:0051235 4 0.040
establishment of protein localization to organelle GO:0072594 4 0.035
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.032
positive regulation of transport GO:0051050 2 0.031
regulation of protein catabolic process GO:0042176 1 0.031
cellular macromolecule metabolic process GO:0044260 391 0.030
negative regulation of protein phosphorylation GO:0001933 4 0.030
single organism metabolic process GO:0044710 217 0.030
positive regulation of catabolic process GO:0009896 4 0.029
eye development GO:0001654 277 0.028
meiotic nuclear division GO:0007126 4 0.027
regulation of protein ubiquitination GO:0031396 3 0.027
nitrogen compound metabolic process GO:0006807 319 0.026
amine metabolic process GO:0009308 2 0.026
regulation of macromolecule metabolic process GO:0060255 317 0.026
lipid storage GO:0019915 1 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.025
cellular response to external stimulus GO:0071496 2 0.025
cell surface receptor signaling pathway GO:0007166 325 0.024
cellular amine metabolic process GO:0044106 2 0.024
protein metabolic process GO:0019538 183 0.024
regulation of developmental process GO:0050793 247 0.024
protein acetylation GO:0006473 2 0.023
regulation of protein transport GO:0051223 3 0.023
leukocyte proliferation GO:0070661 1 0.023
macroautophagy GO:0016236 1 0.023
regulation of protein complex assembly GO:0043254 3 0.023
multicellular organism growth GO:0035264 4 0.023
regulation of multicellular organism growth GO:0040014 4 0.022
cellular ketone metabolic process GO:0042180 11 0.022
response to stress GO:0006950 263 0.022
protein import GO:0017038 3 0.022
regulation of cell activation GO:0050865 1 0.022
peptidyl lysine acetylation GO:0018394 2 0.021
regulation of reproductive process GO:2000241 4 0.021
development of primary female sexual characteristics GO:0046545 4 0.021
positive regulation of cellular component biogenesis GO:0044089 3 0.021
signal transduction GO:0007165 455 0.021
neuron differentiation GO:0030182 353 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.020
cellular response to starvation GO:0009267 1 0.020
b cell activation GO:0042113 2 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
rna localization GO:0006403 4 0.020
cell morphogenesis GO:0000902 289 0.020
cytoskeleton dependent cytokinesis GO:0061640 3 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
mononuclear cell proliferation GO:0032943 1 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
membrane fusion GO:0061025 2 0.019
autophagy GO:0006914 4 0.019
g1 s transition of mitotic cell cycle GO:0000082 1 0.019
negative regulation of biological process GO:0048519 304 0.019
inositol lipid mediated signaling GO:0048017 2 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
regulation of response to stimulus GO:0048583 269 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
regulation of cytokine production GO:0001817 3 0.019
mitochondrion organization GO:0007005 4 0.019
central nervous system development GO:0007417 387 0.019
regulation of circadian rhythm GO:0042752 4 0.018
protein dephosphorylation GO:0006470 3 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
nuclear transport GO:0051169 4 0.018
regulation of tube size GO:0035150 2 0.018
organic substance biosynthetic process GO:1901576 289 0.018
transcription dna templated GO:0006351 181 0.018
rna metabolic process GO:0016070 219 0.018
ubiquitin dependent protein catabolic process GO:0006511 3 0.018
positive regulation of protein complex assembly GO:0031334 2 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
stem cell maintenance GO:0019827 4 0.017
protein acylation GO:0043543 3 0.017
cellular protein catabolic process GO:0044257 4 0.017
cellular response to nutrient levels GO:0031669 2 0.017
negative regulation of cellular process GO:0048523 283 0.017
generation of neurons GO:0048699 385 0.017
meiotic cell cycle process GO:1903046 3 0.017
nuclear import GO:0051170 3 0.017
cell cycle g1 s phase transition GO:0044843 1 0.017
meiotic chromosome segregation GO:0045132 3 0.017
single organism nuclear import GO:1902593 3 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
endocrine process GO:0050886 2 0.017
death GO:0016265 121 0.017
internal protein amino acid acetylation GO:0006475 2 0.017
system process GO:0003008 185 0.016
lymphocyte proliferation GO:0046651 1 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
single organism organelle organization GO:1902589 199 0.016
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.016
modification dependent protein catabolic process GO:0019941 3 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
positive regulation of map kinase activity GO:0043406 3 0.016
negative regulation of kinase activity GO:0033673 4 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
regulation of biological quality GO:0065008 263 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
head development GO:0060322 303 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
neuron development GO:0048666 262 0.016
brain development GO:0007420 293 0.016
stem cell proliferation GO:0072089 4 0.016
organic cyclic compound metabolic process GO:1901360 301 0.015
regulation of cellular component organization GO:0051128 86 0.015
cellular response to radiation GO:0071478 4 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
nuclear export GO:0051168 1 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
negative regulation of defense response GO:0031348 2 0.015
gtp catabolic process GO:0006184 2 0.015
regulation of gene expression GO:0010468 265 0.015
response to uv GO:0009411 3 0.015
protein secretion GO:0009306 1 0.015
negative regulation of signal transduction GO:0009968 94 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
positive regulation of cell cycle GO:0045787 3 0.015
regulation of synapse organization GO:0050807 3 0.015
organelle organization GO:0006996 227 0.015
single organism membrane fusion GO:0044801 2 0.015
protein modification process GO:0036211 100 0.015
hormone biosynthetic process GO:0042446 3 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
regulation of blood vessel size GO:0050880 2 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.015
entrainment of circadian clock GO:0009649 2 0.015
golgi vesicle transport GO:0048193 3 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
negative regulation of catabolic process GO:0009895 3 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
locomotor rhythm GO:0045475 3 0.014
cellular response to organic substance GO:0071310 105 0.014
protein targeting to nucleus GO:0044744 3 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
g2 dna damage checkpoint GO:0031572 3 0.014
response to external stimulus GO:0009605 264 0.014
cell aging GO:0007569 2 0.014
negative regulation of cellular catabolic process GO:0031330 3 0.014
rna transport GO:0050658 2 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
germ line stem cell maintenance GO:0030718 2 0.014
regulation of cell communication GO:0010646 232 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
cellular protein modification process GO:0006464 100 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
nucleic acid templated transcription GO:0097659 181 0.014
release of sequestered calcium ion into cytosol GO:0051209 3 0.014
adult behavior GO:0030534 2 0.014
secondary metabolic process GO:0019748 3 0.014
regulation of metabolic process GO:0019222 359 0.014
regulation of protein targeting GO:1903533 2 0.014
regulation of primary metabolic process GO:0080090 311 0.014
oxoacid metabolic process GO:0043436 31 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
spermatid differentiation GO:0048515 2 0.013
spindle assembly involved in mitosis GO:0090307 1 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
regulation of blood pressure GO:0008217 1 0.013
rna modification GO:0009451 2 0.013
negative regulation of secretion by cell GO:1903531 2 0.013
positive regulation of striated muscle tissue development GO:0045844 1 0.013
regulation of cell shape GO:0008360 1 0.013
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.013
protein localization to plasma membrane GO:0072659 1 0.013
regulation of gtpase activity GO:0043087 2 0.013
positive regulation of cell activation GO:0050867 1 0.013
meiosis i GO:0007127 1 0.013
regulation of cell differentiation GO:0045595 142 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
heart development GO:0007507 313 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
compound eye development GO:0048749 2 0.013
regulation of intracellular ph GO:0051453 1 0.013
stem cell division GO:0017145 1 0.013
cell death GO:0008219 121 0.013
response to drug GO:0042493 3 0.013
phagocytosis GO:0006909 3 0.013
small molecule metabolic process GO:0044281 77 0.013
regulation of chromosome segregation GO:0051983 1 0.013
interspecies interaction between organisms GO:0044419 4 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
retina morphogenesis in camera type eye GO:0060042 79 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.012
regulation of rna metabolic process GO:0051252 224 0.012
protein import into nucleus GO:0006606 3 0.012
lipid homeostasis GO:0055088 3 0.012
organelle fusion GO:0048284 3 0.012
regulation of jun kinase activity GO:0043506 3 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
septum transversum development GO:0003343 4 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
cellular component biogenesis GO:0044085 178 0.012
regulation of response to cytokine stimulus GO:0060759 3 0.012
regulation of hormone secretion GO:0046883 2 0.012
actin filament polymerization GO:0030041 2 0.012
nucleic acid transport GO:0050657 2 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
positive regulation of cytokine production GO:0001819 2 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
signal transduction in absence of ligand GO:0038034 1 0.012
developmental growth GO:0048589 166 0.012
cellular response to light stimulus GO:0071482 4 0.012
response to topologically incorrect protein GO:0035966 2 0.012
single organism transport GO:0044765 206 0.012
camera type eye development GO:0043010 222 0.012
regulation of biosynthetic process GO:0009889 250 0.012
positive regulation of stem cell proliferation GO:2000648 1 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
mitotic cytokinesis GO:0000281 3 0.012
regulation of endocrine process GO:0044060 2 0.012
macromolecule modification GO:0043412 111 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
lipid catabolic process GO:0016042 4 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
cell projection organization GO:0030030 284 0.012
regulation of signaling GO:0023051 235 0.012
cell substrate adhesion GO:0031589 4 0.012
positive regulation of myeloid cell differentiation GO:0045639 2 0.012
establishment of rna localization GO:0051236 3 0.012
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
b cell differentiation GO:0030183 1 0.011
homeostatic process GO:0042592 142 0.011
protein localization to nucleus GO:0034504 3 0.011
positive regulation of immune effector process GO:0002699 3 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
regulation of jak stat cascade GO:0046425 3 0.011
nucleic acid metabolic process GO:0090304 244 0.011
response to organic substance GO:0010033 153 0.011
immune system process GO:0002376 241 0.011
hormone transport GO:0009914 2 0.011
regulation of inflammatory response GO:0050727 2 0.011
positive regulation of cellular process GO:0048522 201 0.011
negative regulation of response to cytokine stimulus GO:0060761 2 0.011
negative regulation of signaling GO:0023057 96 0.011
cellular component morphogenesis GO:0032989 336 0.011
regulation of binding GO:0051098 3 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
female sex differentiation GO:0046660 4 0.011
endocrine hormone secretion GO:0060986 2 0.011
sensory organ development GO:0007423 393 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
immunoglobulin mediated immune response GO:0016064 3 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
regulation of synapse assembly GO:0051963 3 0.011
response to hydrogen peroxide GO:0042542 3 0.011
eye morphogenesis GO:0048592 144 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
protein polymerization GO:0051258 4 0.011
digestive system development GO:0055123 289 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
tissue remodeling GO:0048771 4 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
single organism localization GO:1902578 225 0.011
heterocycle metabolic process GO:0046483 290 0.011
digestive tract development GO:0048565 265 0.011
endosomal transport GO:0016197 2 0.011
negative regulation of protein complex assembly GO:0031333 1 0.011
histone h3 k4 methylation GO:0051568 2 0.010
positive regulation of cell division GO:0051781 2 0.010
organic acid metabolic process GO:0006082 31 0.010
negative regulation of cytokine production GO:0001818 1 0.010
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.010
regulation of mitochondrion organization GO:0010821 1 0.010
nucleobase containing compound metabolic process GO:0006139 274 0.010
hormone secretion GO:0046879 2 0.010
positive regulation of biological process GO:0048518 253 0.010
positive regulation of blood circulation GO:1903524 2 0.010
morphogenesis of an epithelium GO:0002009 333 0.010
microtubule organizing center organization GO:0031023 1 0.010
double strand break repair GO:0006302 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
cell projection morphogenesis GO:0048858 244 0.010
primary neural tube formation GO:0014020 1 0.010
membrane lipid biosynthetic process GO:0046467 2 0.010
cell part morphogenesis GO:0032990 246 0.010
positive regulation of translation GO:0045727 1 0.010
atp catabolic process GO:0006200 4 0.010
heterocycle biosynthetic process GO:0018130 215 0.010
cellular transition metal ion homeostasis GO:0046916 3 0.010
spermatid development GO:0007286 2 0.010
b cell mediated immunity GO:0019724 3 0.010

wdfy2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
organ system cancer DOID:0050686 0 0.017
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
disease of metabolism DOID:0014667 0 0.016
nervous system disease DOID:863 0 0.016