Danio rerio

0 known processes

tprb

translocated promoter region b (to activated MET oncogene)

(Aliases: si:dkey-97o5.5,wu:fi76g05,tpr)

tprb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tube morphogenesis GO:0035239 349 0.136
digestive tract morphogenesis GO:0048546 231 0.092
digestive tract development GO:0048565 265 0.081
digestive system development GO:0055123 289 0.066
heart morphogenesis GO:0003007 156 0.062
negative regulation of sequestering of calcium ion GO:0051283 4 0.059
epithelial tube morphogenesis GO:0060562 148 0.057
positive regulation of transport GO:0051050 2 0.057
Human
embryonic heart tube morphogenesis GO:0003143 108 0.056
protein targeting to nucleus GO:0044744 3 0.054
Human
regulation of establishment of protein localization GO:0070201 4 0.052
Human
cellular component movement GO:0006928 335 0.052
organelle organization GO:0006996 227 0.052
Human
b cell activation GO:0042113 2 0.050
purine nucleoside monophosphate catabolic process GO:0009128 4 0.049
embryonic heart tube development GO:0035050 133 0.047
regulation of biological quality GO:0065008 263 0.046
female gonad development GO:0008585 4 0.045
hematopoietic or lymphoid organ development GO:0048534 191 0.044
heart development GO:0007507 313 0.041
regulation of multicellular organismal process GO:0051239 277 0.041
single organism nuclear import GO:1902593 3 0.040
Human
embryonic organ morphogenesis GO:0048562 274 0.040
oocyte anterior posterior axis specification GO:0007314 4 0.039
localization of cell GO:0051674 244 0.038
transport GO:0006810 220 0.037
Human
cellular response to external stimulus GO:0071496 2 0.037
rna localization GO:0006403 4 0.037
Human
protein import GO:0017038 3 0.037
Human
response to stress GO:0006950 263 0.037
Human
nuclear import GO:0051170 3 0.037
Human
development of primary female sexual characteristics GO:0046545 4 0.037
regionalization GO:0003002 274 0.036
maternal determination of anterior posterior axis embryo GO:0008358 4 0.035
spermatid differentiation GO:0048515 2 0.034
regulation of protein transport GO:0051223 3 0.034
Human
spermatid development GO:0007286 2 0.034
single organism organelle organization GO:1902589 199 0.034
Human
nucleocytoplasmic transport GO:0006913 4 0.034
Human
determination of bilateral symmetry GO:0009855 204 0.033
specification of symmetry GO:0009799 204 0.033
larval development GO:0002164 2 0.033
Worm
cellular response to starvation GO:0009267 1 0.033
cellular component assembly GO:0022607 170 0.032
Human
immune system development GO:0002520 191 0.031
immune system process GO:0002376 241 0.031
ribonucleoside monophosphate catabolic process GO:0009158 4 0.031
hepaticobiliary system development GO:0061008 98 0.030
atp catabolic process GO:0006200 4 0.030
protein localization to nucleus GO:0034504 3 0.030
Human
regulation of protein import into nucleus GO:0042306 2 0.030
Human
regulation of sequestering of calcium ion GO:0051282 4 0.030
establishment of protein localization to organelle GO:0072594 4 0.030
Human
single organism localization GO:1902578 225 0.029
Human
positive regulation of cellular component biogenesis GO:0044089 3 0.029
Human
cellular component biogenesis GO:0044085 178 0.029
Human
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.029
intracellular mrna localization GO:0008298 1 0.028
female sex differentiation GO:0046660 4 0.028
cell migration GO:0016477 237 0.028
sequestering of calcium ion GO:0051208 3 0.027
single organism metabolic process GO:0044710 217 0.027
Human
response to uv GO:0009411 3 0.027
aging GO:0007568 2 0.026
embryonic organ development GO:0048568 381 0.026
macromolecular complex assembly GO:0065003 35 0.026
Human
cell motility GO:0048870 244 0.026
developmental growth GO:0048589 166 0.026
nucleoside monophosphate catabolic process GO:0009125 4 0.025
cellular response to nutrient levels GO:0031669 2 0.025
liver development GO:0001889 96 0.024
sequestering of metal ion GO:0051238 3 0.024
multicellular organism growth GO:0035264 4 0.024
fertilization GO:0009566 3 0.024
mesenchymal cell differentiation GO:0048762 87 0.024
amine metabolic process GO:0009308 2 0.024
cellular response to extracellular stimulus GO:0031668 2 0.023
negative regulation of epithelial cell proliferation GO:0050680 1 0.023
multicellular organismal reproductive process GO:0048609 35 0.022
determination of left right symmetry GO:0007368 179 0.022
production of molecular mediator of immune response GO:0002440 2 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
meiotic nuclear division GO:0007126 4 0.021
lipid storage GO:0019915 1 0.021
camera type eye development GO:0043010 222 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
regulation of cytoplasmic transport GO:1903649 4 0.020
Human
maintenance of location GO:0051235 4 0.020
regulation of protein complex assembly GO:0043254 3 0.020
Human
stem cell maintenance GO:0019827 4 0.020
determination of heart left right asymmetry GO:0061371 117 0.020
heart looping GO:0001947 94 0.020
somitogenesis GO:0001756 87 0.019
protein import into nucleus GO:0006606 3 0.019
Human
neural crest cell development GO:0014032 62 0.019
dna catabolic process GO:0006308 1 0.019
regulation of meiotic cell cycle GO:0051445 1 0.019
gastrulation GO:0007369 208 0.019
response to nutrient GO:0007584 3 0.019
eye development GO:0001654 277 0.019
anterior posterior pattern specification GO:0009952 152 0.019
photoreceptor cell development GO:0042461 40 0.019
cellular amine metabolic process GO:0044106 2 0.018
stem cell division GO:0017145 1 0.018
cellular ketone metabolic process GO:0042180 11 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
Human
regulation of epithelial cell proliferation GO:0050678 3 0.018
photoreceptor cell differentiation GO:0046530 55 0.018
cellular macromolecule metabolic process GO:0044260 391 0.018
Human
b cell mediated immunity GO:0019724 3 0.017
organic acid metabolic process GO:0006082 31 0.017
single organism cellular localization GO:1902580 46 0.017
Human
regulation of cellular amine metabolic process GO:0033238 0 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
cellular component assembly involved in morphogenesis GO:0010927 107 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
immunoglobulin mediated immune response GO:0016064 3 0.017
signal transduction GO:0007165 455 0.017
Human
regulation of cellular ketone metabolic process GO:0010565 7 0.017
rna polyadenylation GO:0043631 2 0.017
regulation of metal ion transport GO:0010959 4 0.017
regulation of histone methylation GO:0031060 3 0.016
cellular component morphogenesis GO:0032989 336 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
response to glucocorticoid GO:0051384 1 0.016
establishment of localization GO:0051234 244 0.016
Human
aorta development GO:0035904 4 0.016
response to wounding GO:0009611 116 0.016
cytokinesis GO:0000910 3 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
positive regulation of biological process GO:0048518 253 0.016
Human
retina development in camera type eye GO:0060041 146 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
polarized epithelial cell differentiation GO:0030859 4 0.015
neuron differentiation GO:0030182 353 0.015
negative regulation of dna metabolic process GO:0051053 4 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
gland development GO:0048732 143 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
Human
ovulation cycle process GO:0022602 2 0.015
segmentation GO:0035282 97 0.015
regulation of protein targeting GO:1903533 2 0.015
Human
positive regulation of catabolic process GO:0009896 4 0.015
phagocytosis GO:0006909 3 0.015
cellular aromatic compound metabolic process GO:0006725 295 0.015
Human
nucleobase containing compound metabolic process GO:0006139 274 0.015
Human
nitrogen compound metabolic process GO:0006807 319 0.015
Human
vasculature development GO:0001944 278 0.015
tissue remodeling GO:0048771 4 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
establishment of localization in cell GO:0051649 77 0.014
Human
blood vessel morphogenesis GO:0048514 216 0.014
positive regulation of chromatin modification GO:1903310 1 0.014
Human
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
Human
dna biosynthetic process GO:0071897 3 0.014
ribosome assembly GO:0042255 1 0.014
protein modification process GO:0036211 100 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.014
immune response GO:0006955 28 0.014
stem cell proliferation GO:0072089 4 0.014
cell cycle arrest GO:0007050 1 0.014
organelle assembly GO:0070925 110 0.014
Human
somatic cell dna recombination GO:0016444 1 0.014
sensory organ development GO:0007423 393 0.014
lipid metabolic process GO:0006629 52 0.014
regulation of reproductive process GO:2000241 4 0.013
stem cell development GO:0048864 82 0.013
neurotransmitter transport GO:0006836 2 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
Human
multi organism process GO:0051704 134 0.013
blood vessel development GO:0001568 246 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
small molecule metabolic process GO:0044281 77 0.013
sexual reproduction GO:0019953 36 0.013
immunoglobulin production GO:0002377 1 0.013
regulation of protein catabolic process GO:0042176 1 0.013
Human
rrna catabolic process GO:0016075 1 0.013
meiotic cell cycle process GO:1903046 3 0.013
eye photoreceptor cell differentiation GO:0001754 45 0.013
epithelial cell differentiation GO:0030855 116 0.013
regulation of cell shape GO:0008360 1 0.013
regulation of cellular component organization GO:0051128 86 0.013
Human
positive regulation of dna metabolic process GO:0051054 1 0.013
Human
regulation of programmed cell death GO:0043067 101 0.012
regulation of calcium ion transport GO:0051924 2 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
regulation of developmental process GO:0050793 247 0.012
protein complex biogenesis GO:0070271 30 0.012
Human
meiotic chromosome segregation GO:0045132 3 0.012
somatic muscle development GO:0007525 4 0.012
cellular nitrogen compound metabolic process GO:0034641 290 0.012
Human
neural crest cell differentiation GO:0014033 72 0.012
organic cyclic compound biosynthetic process GO:1901362 223 0.012
Human
definitive hemopoiesis GO:0060216 18 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
oxoacid metabolic process GO:0043436 31 0.012
head development GO:0060322 303 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
Human
response to carbohydrate GO:0009743 3 0.011
release of sequestered calcium ion into cytosol GO:0051209 3 0.011
regulation of wound healing GO:0061041 2 0.011
cranial nerve development GO:0021545 42 0.011
mesenchymal cell development GO:0014031 78 0.011
post embryonic organ development GO:0048569 4 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
Human
nuclear transport GO:0051169 4 0.011
Human
calcium ion transport into cytosol GO:0060402 3 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
positive regulation of epithelial cell proliferation GO:0050679 1 0.011
regulation of binding GO:0051098 3 0.011
midbrain development GO:0030901 28 0.011
neuroblast proliferation GO:0007405 2 0.011
signal transduction by p53 class mediator GO:0072331 13 0.011
cellular component disassembly GO:0022411 1 0.011
pole plasm assembly GO:0007315 4 0.011
negative regulation of histone modification GO:0031057 1 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
hemopoiesis GO:0030097 183 0.011
organic cyclic compound metabolic process GO:1901360 301 0.011
Human
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
positive regulation of cell cycle GO:0045787 3 0.011
Human
tissue regeneration GO:0042246 74 0.011
eye photoreceptor cell development GO:0042462 30 0.011
locomotion GO:0040011 313 0.010
Worm
ovulation cycle GO:0042698 2 0.010
skeletal system development GO:0001501 181 0.010
regulation of synapse assembly GO:0051963 3 0.010
regulation of dendrite morphogenesis GO:0048814 3 0.010
cellular hormone metabolic process GO:0034754 19 0.010
positive regulation of chromosome organization GO:2001252 1 0.010
Human
negative regulation of biological process GO:0048519 304 0.010
Human
regulation of synapse organization GO:0050807 3 0.010
cell cycle GO:0007049 93 0.010
Human
nitric oxide metabolic process GO:0046209 2 0.010
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
positive regulation of immune effector process GO:0002699 3 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010

tprb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.078
cancer DOID:162 0 0.033
disease of cellular proliferation DOID:14566 0 0.033
organ system cancer DOID:0050686 0 0.032
nervous system disease DOID:863 0 0.017
cardiovascular system disease DOID:1287 0 0.011
sensory system disease DOID:0050155 0 0.010
disease of metabolism DOID:0014667 0 0.010