Danio rerio

0 known processes

pgls

6-phosphogluconolactonase

(Aliases: wu:fb11g07,zgc:100853)

pgls biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic cyclic compound metabolic process GO:1901360 301 0.053
regulation of cellular metabolic process GO:0031323 320 0.045
positive regulation of cellular catabolic process GO:0031331 3 0.044
positive regulation of transport GO:0051050 2 0.044
regulation of metabolic process GO:0019222 359 0.043
mitochondrion organization GO:0007005 4 0.043
heterocycle metabolic process GO:0046483 290 0.041
regulation of reactive oxygen species metabolic process GO:2000377 2 0.040
nitrogen compound metabolic process GO:0006807 319 0.040
cellular biosynthetic process GO:0044249 286 0.039
organic cyclic compound biosynthetic process GO:1901362 223 0.037
heterocycle biosynthetic process GO:0018130 215 0.037
regulation of establishment of protein localization GO:0070201 4 0.037
macromolecule biosynthetic process GO:0009059 227 0.037
aging GO:0007568 2 0.036
larval development GO:0002164 2 0.035
response to drug GO:0042493 3 0.035
cellular response to external stimulus GO:0071496 2 0.035
positive regulation of cell cycle GO:0045787 3 0.034
positive regulation of catabolic process GO:0009896 4 0.034
response to stress GO:0006950 263 0.032
regulation of nitrogen compound metabolic process GO:0051171 251 0.032
organic substance biosynthetic process GO:1901576 289 0.032
rna metabolic process GO:0016070 219 0.031
regulation of transcription dna templated GO:0006355 213 0.030
gtp metabolic process GO:0046039 4 0.030
lipid storage GO:0019915 1 0.030
cellular nitrogen compound biosynthetic process GO:0044271 218 0.030
tube morphogenesis GO:0035239 349 0.029
response to external stimulus GO:0009605 264 0.029
nuclear transport GO:0051169 4 0.028
cellular macromolecule biosynthetic process GO:0034645 224 0.028
transcription dna templated GO:0006351 181 0.028
nucleobase containing compound biosynthetic process GO:0034654 205 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.027
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.026
cellular response to extracellular stimulus GO:0031668 2 0.026
cellular aromatic compound metabolic process GO:0006725 295 0.026
response to chemical GO:0042221 320 0.026
small molecule metabolic process GO:0044281 77 0.025
protein targeting to nucleus GO:0044744 3 0.025
digestive tract development GO:0048565 265 0.025
embryonic organ development GO:0048568 381 0.025
cellular macromolecule metabolic process GO:0044260 391 0.024
regulation of protein targeting GO:1903533 2 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
cellular amine metabolic process GO:0044106 2 0.024
negative regulation of kinase activity GO:0033673 4 0.024
regulation of primary metabolic process GO:0080090 311 0.024
nucleic acid metabolic process GO:0090304 244 0.024
establishment of protein localization to organelle GO:0072594 4 0.023
positive regulation of biological process GO:0048518 253 0.023
negative regulation of protein kinase activity GO:0006469 4 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.023
rna biosynthetic process GO:0032774 181 0.023
hormone secretion GO:0046879 2 0.023
response to topologically incorrect protein GO:0035966 2 0.023
maintenance of location GO:0051235 4 0.023
transmembrane transport GO:0055085 120 0.023
signal transduction GO:0007165 455 0.023
regulation of protein complex assembly GO:0043254 3 0.022
morphogenesis of an epithelium GO:0002009 333 0.022
regulation of signal transduction GO:0009966 225 0.022
cellular response to starvation GO:0009267 1 0.022
regulation of rna biosynthetic process GO:2001141 213 0.022
single organism metabolic process GO:0044710 217 0.022
positive regulation of nucleoside metabolic process GO:0045979 1 0.022
gene expression GO:0010467 252 0.022
nucleic acid templated transcription GO:0097659 181 0.022
protein localization to nucleus GO:0034504 3 0.022
biosynthetic process GO:0009058 294 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
single organism nuclear import GO:1902593 3 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
protein import GO:0017038 3 0.021
regulation of multicellular organism growth GO:0040014 4 0.021
regulation of protein transport GO:0051223 3 0.021
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
regulation of intracellular protein transport GO:0033157 3 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.021
gtp catabolic process GO:0006184 2 0.020
amine metabolic process GO:0009308 2 0.020
adult behavior GO:0030534 2 0.020
cellular response to nutrient levels GO:0031669 2 0.020
peptide transport GO:0015833 1 0.020
meiotic nuclear division GO:0007126 4 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
regulation of biosynthetic process GO:0009889 250 0.020
aromatic compound biosynthetic process GO:0019438 217 0.020
regulation of protein import into nucleus GO:0042306 2 0.020
cellular component assembly GO:0022607 170 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.020
regulation of binding GO:0051098 3 0.020
multicellular organism growth GO:0035264 4 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.019
regulation of biological quality GO:0065008 263 0.019
regulation of rna metabolic process GO:0051252 224 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.019
cellular ketone metabolic process GO:0042180 11 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
regionalization GO:0003002 274 0.019
single organism localization GO:1902578 225 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
muscle structure development GO:0061061 196 0.019
single organism transport GO:0044765 206 0.019
proteasomal protein catabolic process GO:0010498 2 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
anterior posterior pattern specification GO:0009952 152 0.019
cellular nitrogen compound metabolic process GO:0034641 290 0.019
modification dependent protein catabolic process GO:0019941 3 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.019
transport GO:0006810 220 0.018
regulation of response to extracellular stimulus GO:0032104 1 0.018
regulation of hormone secretion GO:0046883 2 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
regulation of protein catabolic process GO:0042176 1 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
organic acid metabolic process GO:0006082 31 0.018
nucleoside monophosphate catabolic process GO:0009125 4 0.018
cellular protein catabolic process GO:0044257 4 0.018
regulation of circadian rhythm GO:0042752 4 0.018
membrane fusion GO:0061025 2 0.018
single organism membrane fusion GO:0044801 2 0.018
phosphorus metabolic process GO:0006793 109 0.018
regulation of gene expression GO:0010468 265 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
stem cell maintenance GO:0019827 4 0.018
cell cycle g1 s phase transition GO:0044843 1 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.017
rna localization GO:0006403 4 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
cellular component morphogenesis GO:0032989 336 0.017
regulation of response to stimulus GO:0048583 269 0.017
positive regulation of secretion GO:0051047 1 0.017
hormone transport GO:0009914 2 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
ion transport GO:0006811 114 0.017
regulation of cell communication GO:0010646 232 0.017
negative regulation of cellular process GO:0048523 283 0.017
positive regulation of nucleotide catabolic process GO:0030813 1 0.017
central nervous system development GO:0007417 387 0.017
positive regulation of apoptotic signaling pathway GO:2001235 1 0.016
negative regulation of biological process GO:0048519 304 0.016
negative regulation of protein transport GO:0051224 3 0.016
cellular component biogenesis GO:0044085 178 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
autophagy GO:0006914 4 0.016
regulation of signaling GO:0023051 235 0.016
regulation of programmed cell death GO:0043067 101 0.016
cellular component disassembly GO:0022411 1 0.016
meiotic cell cycle process GO:1903046 3 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
regulation of cell activation GO:0050865 1 0.016
muscle cell differentiation GO:0042692 139 0.016
chordate embryonic development GO:0043009 271 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
response to nutrient GO:0007584 3 0.016
phagocytosis GO:0006909 3 0.016
regulation of cytokine production GO:0001817 3 0.016
positive regulation of cellular process GO:0048522 201 0.016
establishment of localization GO:0051234 244 0.016
nuclear import GO:0051170 3 0.016
heart development GO:0007507 313 0.016
immune system process GO:0002376 241 0.015
regulation of protein binding GO:0043393 3 0.015
protein import into nucleus GO:0006606 3 0.015
negative regulation of catabolic process GO:0009895 3 0.015
regulation of developmental process GO:0050793 247 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
localization of cell GO:0051674 244 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
regulation of reproductive process GO:2000241 4 0.015
endoplasmic reticulum unfolded protein response GO:0030968 2 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
atp catabolic process GO:0006200 4 0.015
oxoacid metabolic process GO:0043436 31 0.015
digestive system development GO:0055123 289 0.015
ameboidal type cell migration GO:0001667 143 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
carbohydrate homeostasis GO:0033500 1 0.015
response to carbohydrate GO:0009743 3 0.015
protein stabilization GO:0050821 2 0.015
regulation of gtpase activity GO:0043087 2 0.015
negative regulation of protein complex assembly GO:0031333 1 0.015
regulation of blood pressure GO:0008217 1 0.015
protein localization to plasma membrane GO:0072659 1 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
muscle cell development GO:0055001 115 0.014
nucleobase containing compound transport GO:0015931 2 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
response to organic substance GO:0010033 153 0.014
determination of bilateral symmetry GO:0009855 204 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
cellular component movement GO:0006928 335 0.014
reactive oxygen species metabolic process GO:0072593 6 0.014
cell morphogenesis GO:0000902 289 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.014
gland development GO:0048732 143 0.014
locomotion GO:0040011 313 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
cytokinesis GO:0000910 3 0.014
striated muscle cell differentiation GO:0051146 129 0.014
response to monosaccharide GO:0034284 3 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
cell migration GO:0016477 237 0.014
regulation of transmembrane transporter activity GO:0022898 2 0.014
negative regulation of map kinase activity GO:0043407 2 0.014
positive regulation of cellular component biogenesis GO:0044089 3 0.013
cell death GO:0008219 121 0.013
cellular response to radiation GO:0071478 4 0.013
response to uv GO:0009411 3 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
organelle organization GO:0006996 227 0.013
rna transport GO:0050658 2 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
regulation of metal ion transport GO:0010959 4 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
tissue remodeling GO:0048771 4 0.013
single organism biosynthetic process GO:0044711 71 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
negative regulation of protein localization to nucleus GO:1900181 2 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
positive regulation of cell adhesion GO:0045785 1 0.013
intracellular signal transduction GO:0035556 85 0.013
spermatid differentiation GO:0048515 2 0.013
developmental programmed cell death GO:0010623 4 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
organelle fusion GO:0048284 3 0.013
phagocytosis engulfment GO:0006911 1 0.012
regulation of cell differentiation GO:0045595 142 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
apoptotic process GO:0006915 116 0.012
regulation of transporter activity GO:0032409 2 0.012
apoptotic process involved in development GO:1902742 2 0.012
regulation of dendrite development GO:0050773 3 0.012
blood circulation GO:0008015 87 0.012
cellular response to stress GO:0033554 62 0.012
response to hexose GO:0009746 3 0.012
negative regulation of metabolic process GO:0009892 86 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
system process GO:0003008 185 0.012
negative regulation of protein import into nucleus GO:0042308 2 0.012
er nucleus signaling pathway GO:0006984 2 0.012
meiosis i GO:0007127 1 0.012
regulation of sodium ion transport GO:0002028 2 0.012
neuron differentiation GO:0030182 353 0.012
sensory organ development GO:0007423 393 0.012
establishment of rna localization GO:0051236 3 0.012
cell motility GO:0048870 244 0.012
organelle assembly GO:0070925 110 0.012
cell surface receptor signaling pathway GO:0007166 325 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
small molecule catabolic process GO:0044282 3 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
regulation of multicellular organismal process GO:0051239 277 0.012
nucleic acid transport GO:0050657 2 0.012
positive regulation of cytokine production GO:0001819 2 0.012
neurotransmitter transport GO:0006836 2 0.012
determination of left right symmetry GO:0007368 179 0.011
homeostatic process GO:0042592 142 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
cell cycle arrest GO:0007050 1 0.011
regulation of synapse organization GO:0050807 3 0.011
fatty acid biosynthetic process GO:0006633 4 0.011
spindle assembly GO:0051225 2 0.011
microtubule organizing center organization GO:0031023 1 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
macromolecular complex disassembly GO:0032984 1 0.011
inner ear development GO:0048839 126 0.011
hemopoiesis GO:0030097 183 0.011
vasculature development GO:0001944 278 0.011
protein secretion GO:0009306 1 0.011
nitric oxide metabolic process GO:0046209 2 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
muscle tissue development GO:0060537 110 0.011
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
cellular response to organic substance GO:0071310 105 0.011
somitogenesis GO:0001756 87 0.011
regulation of autophagy GO:0010506 3 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
immune system development GO:0002520 191 0.011
protein complex disassembly GO:0043241 1 0.011
peptidyl serine modification GO:0018209 2 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
striated muscle cell development GO:0055002 108 0.011
regulation of tube size GO:0035150 2 0.011
blood vessel development GO:0001568 246 0.011
death GO:0016265 121 0.011
regulation of inflammatory response GO:0050727 2 0.011
specification of symmetry GO:0009799 204 0.011
viral process GO:0016032 1 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
positive regulation of cell activation GO:0050867 1 0.011
liver development GO:0001889 96 0.011
interspecies interaction between organisms GO:0044419 4 0.011
regulation of apoptotic process GO:0042981 98 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
regulation of lipid transport GO:0032368 4 0.011
reactive oxygen species biosynthetic process GO:1903409 1 0.010
epithelial cell differentiation GO:0030855 116 0.010
macroautophagy GO:0016236 1 0.010
compound eye development GO:0048749 2 0.010
macromolecule modification GO:0043412 111 0.010
multi organism cellular process GO:0044764 2 0.010
membrane invagination GO:0010324 1 0.010
response to corticosteroid GO:0031960 1 0.010
circulatory system process GO:0003013 87 0.010
cellular component assembly involved in morphogenesis GO:0010927 107 0.010
cytoskeleton dependent cytokinesis GO:0061640 3 0.010
glucose homeostasis GO:0042593 1 0.010
germ line stem cell maintenance GO:0030718 2 0.010
protein metabolic process GO:0019538 183 0.010
mitochondrial transport GO:0006839 2 0.010
centrosome organization GO:0051297 1 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
regulation of multicellular organismal development GO:2000026 223 0.010
organic acid catabolic process GO:0016054 3 0.010
blood vessel morphogenesis GO:0048514 216 0.010
endosomal transport GO:0016197 2 0.010
negative regulation of signal transduction GO:0009968 94 0.010
programmed cell death GO:0012501 119 0.010
positive regulation of stress activated mapk cascade GO:0032874 3 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010

pgls disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.021
disease of metabolism DOID:0014667 0 0.019
inherited metabolic disorder DOID:655 0 0.019
disease of cellular proliferation DOID:14566 0 0.016
cancer DOID:162 0 0.015
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
musculoskeletal system disease DOID:17 0 0.012