Danio rerio

33 known processes

sfxn4

sideroflexin 4

(Aliases: zgc:153199,MGC153199,im:7151335,si:ch211-117n7.3)

sfxn4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.080
aging GO:0007568 2 0.048
positive regulation of transport GO:0051050 2 0.044
meiotic nuclear division GO:0007126 4 0.043
maintenance of location GO:0051235 4 0.042
nuclear transport GO:0051169 4 0.041
establishment of protein localization to organelle GO:0072594 4 0.040
nucleocytoplasmic transport GO:0006913 4 0.037
nitrogen compound metabolic process GO:0006807 319 0.037
phagocytosis GO:0006909 3 0.035
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.035
multicellular organism growth GO:0035264 4 0.035
cellular macromolecule metabolic process GO:0044260 391 0.034
amine metabolic process GO:0009308 2 0.034
proteasomal protein catabolic process GO:0010498 2 0.034
cellular nitrogen compound metabolic process GO:0034641 290 0.034
mitochondrion organization GO:0007005 4 0.033
regulation of establishment of protein localization GO:0070201 4 0.033
signal transduction GO:0007165 455 0.033
response to drug GO:0042493 3 0.033
cellular protein catabolic process GO:0044257 4 0.032
regulation of cytokine production GO:0001817 3 0.032
cellular amine metabolic process GO:0044106 2 0.031
regulation of multicellular organism growth GO:0040014 4 0.031
positive regulation of catabolic process GO:0009896 4 0.030
regulation of protein transport GO:0051223 3 0.030
protein import GO:0017038 3 0.030
regulation of mrna processing GO:0050684 3 0.029
ubiquitin dependent protein catabolic process GO:0006511 3 0.029
heterocycle metabolic process GO:0046483 290 0.029
biosynthetic process GO:0009058 294 0.028
lipid storage GO:0019915 1 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
modification dependent macromolecule catabolic process GO:0043632 3 0.028
nucleoside monophosphate catabolic process GO:0009125 4 0.027
single organism metabolic process GO:0044710 217 0.027
single organism nuclear import GO:1902593 3 0.027
modification dependent protein catabolic process GO:0019941 3 0.027
cell surface receptor signaling pathway GO:0007166 325 0.027
protein localization to nucleus GO:0034504 3 0.026
guanosine containing compound catabolic process GO:1901069 2 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
organonitrogen compound metabolic process GO:1901564 74 0.025
regulation of binding GO:0051098 3 0.025
nucleobase containing compound metabolic process GO:0006139 274 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
gtp metabolic process GO:0046039 4 0.025
regulation of nucleocytoplasmic transport GO:0046822 2 0.025
negative regulation of biological process GO:0048519 304 0.024
regulation of cell activation GO:0050865 1 0.024
regulation of cytoplasmic transport GO:1903649 4 0.024
establishment of localization GO:0051234 244 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
central nervous system development GO:0007417 387 0.024
meiotic cell cycle process GO:1903046 3 0.023
organic cyclic compound metabolic process GO:1901360 301 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.023
regulation of metabolic process GO:0019222 359 0.023
organelle organization GO:0006996 227 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
cellular biosynthetic process GO:0044249 286 0.023
regulation of cell shape GO:0008360 1 0.023
positive regulation of cell cycle GO:0045787 3 0.023
regulation of protein localization to nucleus GO:1900180 2 0.023
positive regulation of cellular component biogenesis GO:0044089 3 0.023
gtp catabolic process GO:0006184 2 0.023
regulation of protein catabolic process GO:0042176 1 0.022
cellular macromolecule biosynthetic process GO:0034645 224 0.022
regulation of response to stimulus GO:0048583 269 0.022
cellular component morphogenesis GO:0032989 336 0.022
transcription dna templated GO:0006351 181 0.022
regulation of biosynthetic process GO:0009889 250 0.022
immune system process GO:0002376 241 0.022
cellular component disassembly GO:0022411 1 0.022
nuclear import GO:0051170 3 0.022
regulation of multicellular organismal process GO:0051239 277 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
regulation of primary metabolic process GO:0080090 311 0.022
regulation of meiotic cell cycle GO:0051445 1 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
organic cyclic compound biosynthetic process GO:1901362 223 0.021
gene expression GO:0010467 252 0.021
regulation of protein complex assembly GO:0043254 3 0.021
regulation of protein import into nucleus GO:0042306 2 0.021
protein targeting to nucleus GO:0044744 3 0.021
internal protein amino acid acetylation GO:0006475 2 0.021
regulation of mrna splicing via spliceosome GO:0048024 3 0.021
cellular response to external stimulus GO:0071496 2 0.021
protein secretion GO:0009306 1 0.021
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
atp catabolic process GO:0006200 4 0.021
negative regulation of cellular process GO:0048523 283 0.021
ribonucleoside monophosphate catabolic process GO:0009158 4 0.021
regulation of cellular metabolic process GO:0031323 320 0.021
protein import into nucleus GO:0006606 3 0.021
cytokinesis GO:0000910 3 0.020
regulation of gene expression GO:0010468 265 0.020
response to stress GO:0006950 263 0.020
organic substance biosynthetic process GO:1901576 289 0.020
rna localization GO:0006403 4 0.020
purine nucleoside monophosphate catabolic process GO:0009128 4 0.020
regulation of developmental process GO:0050793 247 0.020
cellular ketone metabolic process GO:0042180 11 0.020
nucleic acid metabolic process GO:0090304 244 0.020
leukocyte proliferation GO:0070661 1 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
cellular component movement GO:0006928 335 0.020
single organism organelle organization GO:1902589 199 0.020
response to uv GO:0009411 3 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.020
multi organism cellular process GO:0044764 2 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
regulation of protein targeting GO:1903533 2 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
small molecule metabolic process GO:0044281 77 0.019
oxoacid metabolic process GO:0043436 31 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
peptidyl lysine acetylation GO:0018394 2 0.019
regulation of biological quality GO:0065008 263 0.019
positive regulation of biological process GO:0048518 253 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
organic acid metabolic process GO:0006082 31 0.019
response to external stimulus GO:0009605 264 0.019
positive regulation of translation GO:0045727 1 0.019
protein metabolic process GO:0019538 183 0.019
response to chemical GO:0042221 320 0.019
nuclear export GO:0051168 1 0.019
cognition GO:0050890 1 0.019
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.019
protein acylation GO:0043543 3 0.019
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
meiotic chromosome segregation GO:0045132 3 0.018
membrane fusion GO:0061025 2 0.018
stem cell maintenance GO:0019827 4 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
rna metabolic process GO:0016070 219 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
locomotion GO:0040011 313 0.018
alternative mrna splicing via spliceosome GO:0000380 1 0.018
regulation of inflammatory response GO:0050727 2 0.018
cell morphogenesis GO:0000902 289 0.018
positive regulation of cytokine production GO:0001819 2 0.018
i kappab kinase nf kappab signaling GO:0007249 4 0.018
single organism membrane fusion GO:0044801 2 0.018
rna biosynthetic process GO:0032774 181 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.018
cellular response to nutrient levels GO:0031669 2 0.018
single organism localization GO:1902578 225 0.018
cell projection organization GO:0030030 284 0.018
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
protein localization to plasma membrane GO:0072659 1 0.018
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
transport GO:0006810 220 0.017
autophagy GO:0006914 4 0.017
cell cycle g1 s phase transition GO:0044843 1 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
negative regulation of catabolic process GO:0009895 3 0.017
cellular response to starvation GO:0009267 1 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
embryo development ending in birth or egg hatching GO:0009792 271 0.017
protein polyubiquitination GO:0000209 4 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
cellular component assembly GO:0022607 170 0.017
aromatic compound biosynthetic process GO:0019438 217 0.017
response to nutrient GO:0007584 3 0.017
positive regulation of cell adhesion GO:0045785 1 0.017
regulation of cell communication GO:0010646 232 0.017
protein acetylation GO:0006473 2 0.017
morphogenesis of an epithelium GO:0002009 333 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
mononuclear cell proliferation GO:0032943 1 0.017
internal peptidyl lysine acetylation GO:0018393 2 0.017
regulation of signaling GO:0023051 235 0.016
generation of neurons GO:0048699 385 0.016
response to topologically incorrect protein GO:0035966 2 0.016
nucleic acid templated transcription GO:0097659 181 0.016
tissue remodeling GO:0048771 4 0.016
sensory organ development GO:0007423 393 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
regulation of protein ubiquitination GO:0031396 3 0.016
negative regulation of cytokine production GO:0001818 1 0.016
regulation of nucleic acid templated transcription GO:1903506 213 0.016
stem cell proliferation GO:0072089 4 0.016
nucleic acid transport GO:0050657 2 0.016
cell motility GO:0048870 244 0.016
regulation of rna metabolic process GO:0051252 224 0.016
cell part morphogenesis GO:0032990 246 0.016
localization of cell GO:0051674 244 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.016
female sex differentiation GO:0046660 4 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
positive regulation of cell activation GO:0050867 1 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
microtubule organizing center organization GO:0031023 1 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
regulation of signal transduction GO:0009966 225 0.015
cellular component biogenesis GO:0044085 178 0.015
negative regulation of kinase activity GO:0033673 4 0.015
organelle fusion GO:0048284 3 0.015
peptidyl serine modification GO:0018209 2 0.015
embryonic organ development GO:0048568 381 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
neuron differentiation GO:0030182 353 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
tube morphogenesis GO:0035239 349 0.015
regulation of reactive oxygen species metabolic process GO:2000377 2 0.015
secondary metabolic process GO:0019748 3 0.015
protein stabilization GO:0050821 2 0.015
positive regulation of map kinase activity GO:0043406 3 0.015
dna templated transcription elongation GO:0006354 3 0.015
death GO:0016265 121 0.015
cellular response to radiation GO:0071478 4 0.015
protein polymerization GO:0051258 4 0.015
carbohydrate homeostasis GO:0033500 1 0.015
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
cell migration GO:0016477 237 0.015
interspecies interaction between organisms GO:0044419 4 0.015
regulation of gtpase activity GO:0043087 2 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
growth GO:0040007 174 0.014
phagocytosis engulfment GO:0006911 1 0.014
female gonad development GO:0008585 4 0.014
positive regulation of gtp catabolic process GO:0033126 1 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
negative regulation of defense response GO:0031348 2 0.014
endosomal transport GO:0016197 2 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
head development GO:0060322 303 0.014
mitochondrial transport GO:0006839 2 0.014
lymphocyte proliferation GO:0046651 1 0.014
eye development GO:0001654 277 0.014
rna transport GO:0050658 2 0.014
double strand break repair GO:0006302 3 0.014
protein complex disassembly GO:0043241 1 0.014
apoptotic process involved in development GO:1902742 2 0.014
negative regulation of cellular catabolic process GO:0031330 3 0.014
positive regulation of secretion GO:0051047 1 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
brain development GO:0007420 293 0.014
system process GO:0003008 185 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
cell projection morphogenesis GO:0048858 244 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
regulation of reproductive process GO:2000241 4 0.014
centrosome organization GO:0051297 1 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
positive regulation of cellular process GO:0048522 201 0.014
regulation of dna templated transcription elongation GO:0032784 3 0.014
cytoskeleton dependent cytokinesis GO:0061640 3 0.013
programmed cell death GO:0012501 119 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
developmental programmed cell death GO:0010623 4 0.013
rna export from nucleus GO:0006405 1 0.013
b cell activation GO:0042113 2 0.013
cell matrix adhesion GO:0007160 4 0.013
regulation of production of molecular mediator of immune response GO:0002700 1 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
regionalization GO:0003002 274 0.013
regulation of autophagy GO:0010506 3 0.013
heart development GO:0007507 313 0.013
regulation of rho protein signal transduction GO:0035023 2 0.013
regulation of transcription dna templated GO:0006355 213 0.013
nucleobase containing compound transport GO:0015931 2 0.013
viral process GO:0016032 1 0.013
macromolecular complex disassembly GO:0032984 1 0.013
response to hexose GO:0009746 3 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
digestive system development GO:0055123 289 0.013
adult behavior GO:0030534 2 0.013
cell death GO:0008219 121 0.013
negative regulation of secretion GO:0051048 2 0.013
regulation of protein polymerization GO:0032271 2 0.013
spermatid development GO:0007286 2 0.013
regulation of synapse organization GO:0050807 3 0.013
peptide transport GO:0015833 1 0.013
meiosis i GO:0007127 1 0.013
stem cell division GO:0017145 1 0.013
positive regulation of immune effector process GO:0002699 3 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
lamellipodium organization GO:0097581 1 0.013
single organism transport GO:0044765 206 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
exocytosis GO:0006887 1 0.012
membrane invagination GO:0010324 1 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
hemopoiesis GO:0030097 183 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
response to organic substance GO:0010033 153 0.012
cellular protein metabolic process GO:0044267 129 0.012
locomotor rhythm GO:0045475 3 0.012
regulation of jun kinase activity GO:0043506 3 0.012
telomere maintenance GO:0000723 1 0.012
cellular response to light stimulus GO:0071482 4 0.012
vasculature development GO:0001944 278 0.012
mrna transport GO:0051028 2 0.012
regulation of cellular component organization GO:0051128 86 0.012
sequestering of metal ion GO:0051238 3 0.012
protein modification process GO:0036211 100 0.012
protein dephosphorylation GO:0006470 3 0.012
macroautophagy GO:0016236 1 0.012
establishment of rna localization GO:0051236 3 0.012
regulation of blood pressure GO:0008217 1 0.012
blood vessel development GO:0001568 246 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
regulation of metal ion transport GO:0010959 4 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
adherens junction organization GO:0034332 4 0.012
macromolecule modification GO:0043412 111 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
intracellular signal transduction GO:0035556 85 0.012
spermatid differentiation GO:0048515 2 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
negative regulation of nuclear division GO:0051784 3 0.012
cellular amide metabolic process GO:0043603 4 0.012
actin filament polymerization GO:0030041 2 0.012
apoptotic process GO:0006915 116 0.012
positive regulation of jnk cascade GO:0046330 3 0.012
ameboidal type cell migration GO:0001667 143 0.012
regulation of organelle assembly GO:1902115 4 0.012
mitotic cytokinesis GO:0000281 3 0.012
translational initiation GO:0006413 3 0.012
developmental growth GO:0048589 166 0.012
mitotic dna integrity checkpoint GO:0044774 4 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.012
rna 3 end processing GO:0031123 2 0.012
cellular localization GO:0051641 97 0.011
g2 dna damage checkpoint GO:0031572 3 0.011
cellular protein modification process GO:0006464 100 0.011
immune system development GO:0002520 191 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
response to monosaccharide GO:0034284 3 0.011
regulation of synapse assembly GO:0051963 3 0.011
activation of mapk activity GO:0000187 3 0.011
negative regulation of metabolic process GO:0009892 86 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
regulation of circadian rhythm GO:0042752 4 0.011
lamellipodium assembly GO:0030032 1 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.011
multi organism process GO:0051704 134 0.011
response to carbohydrate GO:0009743 3 0.011
lipid homeostasis GO:0055088 3 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
compound eye development GO:0048749 2 0.011
glucose homeostasis GO:0042593 1 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
mrna export from nucleus GO:0006406 1 0.011
response to external biotic stimulus GO:0043207 97 0.011
chemosensory behavior GO:0007635 1 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
angiogenesis GO:0001525 158 0.011
regulation of jak stat cascade GO:0046425 3 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
cell substrate adhesion GO:0031589 4 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
regulation of chromosome segregation GO:0051983 1 0.011
digestive tract morphogenesis GO:0048546 231 0.011
calcium ion transport into cytosol GO:0060402 3 0.011
blood vessel morphogenesis GO:0048514 216 0.011
regulation of organ growth GO:0046620 3 0.011
regulation of programmed cell death GO:0043067 101 0.011
negative regulation of map kinase activity GO:0043407 2 0.011
positive regulation of dna templated transcription elongation GO:0032786 1 0.011
regulation of cell death GO:0010941 103 0.011
cellular response to organic substance GO:0071310 105 0.011
golgi vesicle transport GO:0048193 3 0.011
phosphorus metabolic process GO:0006793 109 0.011
somatic stem cell maintenance GO:0035019 1 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.010
negative regulation of response to stimulus GO:0048585 104 0.010
intracellular mrna localization GO:0008298 1 0.010
regulation of apoptotic process GO:0042981 98 0.010
odontogenesis of dentin containing tooth GO:0042475 1 0.010
response to glucose GO:0009749 3 0.010
regulation of muscle contraction GO:0006937 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
circulatory system process GO:0003013 87 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.010
centrosome cycle GO:0007098 1 0.010
sequestering of calcium ion GO:0051208 3 0.010
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.010
single fertilization GO:0007338 3 0.010
protein heterooligomerization GO:0051291 1 0.010
regulation of stem cell proliferation GO:0072091 2 0.010
signal transduction in absence of ligand GO:0038034 1 0.010
response to biotic stimulus GO:0009607 97 0.010

sfxn4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.017
musculoskeletal system disease DOID:17 0 0.015
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.013
disease of metabolism DOID:0014667 0 0.012
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011