Danio rerio

0 known processes

mkrn4

makorin, ring finger protein, 4

(Aliases: wu:fi27c05,fi27c05,si:ch73-237c6.4)

mkrn4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to chemical GO:0042221 320 0.275
response to lipid GO:0033993 60 0.243
response to organic substance GO:0010033 153 0.175
cellular nitrogen compound metabolic process GO:0034641 290 0.174
larval development GO:0002164 2 0.169
signal transduction GO:0007165 455 0.168
regulation of biosynthetic process GO:0009889 250 0.138
positive regulation of cell cycle GO:0045787 3 0.138
regulation of metabolic process GO:0019222 359 0.133
rna metabolic process GO:0016070 219 0.123
regulation of macromolecule metabolic process GO:0060255 317 0.121
heterocycle metabolic process GO:0046483 290 0.120
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.119
organic cyclic compound metabolic process GO:1901360 301 0.118
regulation of multicellular organismal process GO:0051239 277 0.115
cellular response to organic substance GO:0071310 105 0.113
cellular macromolecule biosynthetic process GO:0034645 224 0.111
regulation of primary metabolic process GO:0080090 311 0.105
organic substance biosynthetic process GO:1901576 289 0.105
cellular response to organic cyclic compound GO:0071407 38 0.103
response to vitamin b3 GO:0033552 2 0.103
neuron differentiation GO:0030182 353 0.097
nitrogen compound metabolic process GO:0006807 319 0.088
cellular response to lipid GO:0071396 39 0.084
oocyte maturation GO:0001556 4 0.082
maintenance of location GO:0051235 4 0.082
regulation of cellular metabolic process GO:0031323 320 0.078
stem cell maintenance GO:0019827 4 0.077
cellular biosynthetic process GO:0044249 286 0.077
organic cyclic compound biosynthetic process GO:1901362 223 0.077
regulation of cellular biosynthetic process GO:0031326 245 0.076
rna biosynthetic process GO:0032774 181 0.075
cellular response to chemical stimulus GO:0070887 157 0.074
response to stress GO:0006950 263 0.072
nucleobase containing compound biosynthetic process GO:0034654 205 0.072
biosynthetic process GO:0009058 294 0.069
regulation of nitrogen compound metabolic process GO:0051171 251 0.069
response to hormone GO:0009725 48 0.067
nucleic acid metabolic process GO:0090304 244 0.066
purine nucleoside monophosphate catabolic process GO:0009128 4 0.064
regulation of macromolecule biosynthetic process GO:0010556 225 0.064
neuron development GO:0048666 262 0.063
organonitrogen compound metabolic process GO:1901564 74 0.062
heterocycle biosynthetic process GO:0018130 215 0.061
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.060
regulation of rna biosynthetic process GO:2001141 213 0.060
positive regulation of biological process GO:0048518 253 0.058
transcription dna templated GO:0006351 181 0.058
negative regulation of cytokine production GO:0001818 1 0.054
regulation of biological quality GO:0065008 263 0.053
gene expression GO:0010467 252 0.052
cell morphogenesis GO:0000902 289 0.049
germ line stem cell maintenance GO:0030718 2 0.049
phagocytosis GO:0006909 3 0.049
nucleobase containing compound metabolic process GO:0006139 274 0.047
cellular nitrogen compound biosynthetic process GO:0044271 218 0.047
cellular macromolecule metabolic process GO:0044260 391 0.046
generation of neurons GO:0048699 385 0.046
meiotic cell cycle process GO:1903046 3 0.046
reactive nitrogen species metabolic process GO:2001057 0 0.046
positive regulation of transport GO:0051050 2 0.045
regulation of cell differentiation GO:0045595 142 0.045
positive regulation of catabolic process GO:0009896 4 0.044
single organism metabolic process GO:0044710 217 0.043
morphogenesis of an epithelium GO:0002009 333 0.043
lipid homeostasis GO:0055088 3 0.042
specification of symmetry GO:0009799 204 0.042
lipid storage GO:0019915 1 0.041
response to steroid hormone GO:0048545 35 0.041
regulation of reproductive process GO:2000241 4 0.040
cellular protein catabolic process GO:0044257 4 0.039
regionalization GO:0003002 274 0.039
cellular aromatic compound metabolic process GO:0006725 295 0.038
regulation of nucleic acid templated transcription GO:1903506 213 0.038
response to vitamin GO:0033273 3 0.038
regulation of cytokine production GO:0001817 3 0.038
protein metabolic process GO:0019538 183 0.038
nitric oxide metabolic process GO:0046209 2 0.037
negative regulation of response to stimulus GO:0048585 104 0.036
positive regulation of metabolic process GO:0009893 108 0.036
histone phosphorylation GO:0016572 2 0.035
atp catabolic process GO:0006200 4 0.035
response to endogenous stimulus GO:0009719 83 0.034
positive regulation of cellular catabolic process GO:0031331 3 0.034
microtubule organizing center organization GO:0031023 1 0.034
nucleoside monophosphate catabolic process GO:0009125 4 0.034
regulation of dendrite development GO:0050773 3 0.034
cellular response to stress GO:0033554 62 0.034
positive regulation of cellular process GO:0048522 201 0.034
establishment of endothelial barrier GO:0061028 3 0.034
regulation of synaptic plasticity GO:0048167 1 0.034
determination of left right symmetry GO:0007368 179 0.033
modification dependent macromolecule catabolic process GO:0043632 3 0.032
ribonucleoside monophosphate catabolic process GO:0009158 4 0.032
response to nutrient GO:0007584 3 0.030
regulation of metal ion transport GO:0010959 4 0.030
nucleic acid templated transcription GO:0097659 181 0.030
response to glucocorticoid GO:0051384 1 0.030
negative regulation of multicellular organismal process GO:0051241 69 0.030
regulation of transcription dna templated GO:0006355 213 0.029
regulation of cellular amine metabolic process GO:0033238 0 0.029
female meiotic division GO:0007143 2 0.029
meiotic nuclear division GO:0007126 4 0.029
cell projection morphogenesis GO:0048858 244 0.029
cellular response to biotic stimulus GO:0071216 3 0.029
sensory organ morphogenesis GO:0090596 200 0.029
regulation of protein complex assembly GO:0043254 3 0.029
embryonic organ morphogenesis GO:0048562 274 0.028
alcohol biosynthetic process GO:0046165 2 0.028
regulation of multicellular organismal development GO:2000026 223 0.028
single organism localization GO:1902578 225 0.028
aging GO:0007568 2 0.028
regulation of signaling GO:0023051 235 0.028
cellular response to decreased oxygen levels GO:0036294 1 0.028
heart morphogenesis GO:0003007 156 0.027
tube morphogenesis GO:0035239 349 0.027
heart looping GO:0001947 94 0.027
nitric oxide biosynthetic process GO:0006809 2 0.027
cellular response to extracellular stimulus GO:0031668 2 0.027
neuron projection development GO:0031175 180 0.026
embryonic heart tube morphogenesis GO:0003143 108 0.026
negative regulation of biological process GO:0048519 304 0.026
regulation of molecular function GO:0065009 70 0.026
cellular response to steroid hormone stimulus GO:0071383 31 0.026
fatty acid elongation unsaturated fatty acid GO:0019368 1 0.026
sensory organ development GO:0007423 393 0.026
regulation of gene expression GO:0010468 265 0.025
negative regulation of cellular process GO:0048523 283 0.025
meiosis i GO:0007127 1 0.025
negative regulation of biosynthetic process GO:0009890 55 0.025
cellular response to oxygen levels GO:0071453 1 0.024
rna 3 end processing GO:0031123 2 0.024
cellular lipid catabolic process GO:0044242 3 0.024
oxoacid metabolic process GO:0043436 31 0.024
negative regulation of innate immune response GO:0045824 2 0.024
neuron projection morphogenesis GO:0048812 161 0.024
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.024
determination of bilateral symmetry GO:0009855 204 0.024
cytokinesis GO:0000910 3 0.023
cellular component morphogenesis GO:0032989 336 0.023
organic substance catabolic process GO:1901575 28 0.023
phosphate containing compound metabolic process GO:0006796 108 0.023
positive regulation of cytokine production GO:0001819 2 0.023
regulation of transporter activity GO:0032409 2 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.023
mitochondrion organization GO:0007005 4 0.022
regulation of transmembrane transporter activity GO:0022898 2 0.022
centrosome organization GO:0051297 1 0.022
small molecule metabolic process GO:0044281 77 0.022
regulation of binding GO:0051098 3 0.022
aromatic compound biosynthetic process GO:0019438 217 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.022
mitotic dna integrity checkpoint GO:0044774 4 0.022
macromolecule biosynthetic process GO:0009059 227 0.022
epithelial tube morphogenesis GO:0060562 148 0.022
response to oxygen containing compound GO:1901700 55 0.022
stem cell proliferation GO:0072089 4 0.022
amine metabolic process GO:0009308 2 0.021
cell projection organization GO:0030030 284 0.021
digestive tract morphogenesis GO:0048546 231 0.021
regulation of rna metabolic process GO:0051252 224 0.021
regulation of signal transduction GO:0009966 225 0.021
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.021
transport GO:0006810 220 0.021
regulation of stem cell differentiation GO:2000736 4 0.021
regulation of inflammatory response GO:0050727 2 0.021
g1 s transition of mitotic cell cycle GO:0000082 1 0.021
regulation of nucleoside metabolic process GO:0009118 2 0.021
one carbon compound transport GO:0019755 14 0.021
single fertilization GO:0007338 3 0.021
er nucleus signaling pathway GO:0006984 2 0.020
regulation of sodium ion transport GO:0002028 2 0.020
peptide transport GO:0015833 1 0.020
regulation of cellular protein catabolic process GO:1903362 1 0.020
regulation of programmed cell death GO:0043067 101 0.020
response to carbohydrate GO:0009743 3 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.020
cell fate commitment GO:0045165 99 0.020
heart development GO:0007507 313 0.020
regulation of translational initiation GO:0006446 1 0.020
response to amino acid GO:0043200 2 0.019
endoplasmic reticulum unfolded protein response GO:0030968 2 0.019
muscle structure development GO:0061061 196 0.019
regulation of oocyte development GO:0060281 3 0.019
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.019
intracellular signal transduction GO:0035556 85 0.019
cellular protein modification process GO:0006464 100 0.019
positive regulation of multicellular organismal process GO:0051240 52 0.019
regulation of response to stimulus GO:0048583 269 0.019
negative regulation of rna biosynthetic process GO:1902679 45 0.019
cell cycle g1 s phase transition GO:0044843 1 0.019
digestive system development GO:0055123 289 0.018
cellular ketone metabolic process GO:0042180 11 0.018
reactive oxygen species biosynthetic process GO:1903409 1 0.018
response to hexose GO:0009746 3 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
response to glucose GO:0009749 3 0.018
cellular response to external stimulus GO:0071496 2 0.018
regulation of protein catabolic process GO:0042176 1 0.018
fertilization GO:0009566 3 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
positive regulation of translation GO:0045727 1 0.018
ubiquitin dependent protein catabolic process GO:0006511 3 0.018
hemopoiesis GO:0030097 183 0.017
positive regulation of apoptotic signaling pathway GO:2001235 1 0.017
eye development GO:0001654 277 0.017
multi organism cellular process GO:0044764 2 0.017
gastrulation GO:0007369 208 0.017
cellular response to hypoxia GO:0071456 1 0.017
response to monosaccharide GO:0034284 3 0.017
connective tissue development GO:0061448 99 0.017
death GO:0016265 121 0.017
stem cell differentiation GO:0048863 117 0.017
response to osmotic stress GO:0006970 11 0.017
translational initiation GO:0006413 3 0.017
phosphorus metabolic process GO:0006793 109 0.017
negative regulation of signaling GO:0023057 96 0.017
regulation of cell communication GO:0010646 232 0.016
negative regulation of intracellular transport GO:0032387 3 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
centrosome cycle GO:0007098 1 0.016
regulation of phosphate metabolic process GO:0019220 43 0.016
establishment of localization GO:0051234 244 0.016
cellular component assembly GO:0022607 170 0.016
eye morphogenesis GO:0048592 144 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
chordate embryonic development GO:0043009 271 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
gtp catabolic process GO:0006184 2 0.015
response to topologically incorrect protein GO:0035966 2 0.015
negative regulation of signal transduction GO:0009968 94 0.015
adult behavior GO:0030534 2 0.015
cell part morphogenesis GO:0032990 246 0.015
protein polymerization GO:0051258 4 0.015
regulation of chromosome segregation GO:0051983 1 0.015
multi organism process GO:0051704 134 0.015
anterior posterior pattern specification GO:0009952 152 0.015
negative regulation of cellular biosynthetic process GO:0031327 55 0.015
neuroblast proliferation GO:0007405 2 0.015
digestive tract development GO:0048565 265 0.014
stem cell division GO:0017145 1 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
positive regulation of cellular component biogenesis GO:0044089 3 0.014
protein homooligomerization GO:0051260 3 0.014
negative regulation of type i interferon mediated signaling pathway GO:0060339 1 0.014
cellular protein metabolic process GO:0044267 129 0.014
regulation of blood vessel size GO:0050880 2 0.014
lateral inhibition GO:0046331 1 0.014
negative regulation of response to cytokine stimulus GO:0060761 2 0.014
homeostatic process GO:0042592 142 0.014
cellular response to hormone stimulus GO:0032870 39 0.014
amide transport GO:0042886 12 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
regulation of mrna processing GO:0050684 3 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
positive regulation of cell activation GO:0050867 1 0.013
catechol containing compound metabolic process GO:0009712 2 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
growth GO:0040007 174 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
organic acid metabolic process GO:0006082 31 0.013
regulation of meiotic cell cycle GO:0051445 1 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.013
urea transport GO:0015840 11 0.013
negative regulation of mitosis GO:0045839 3 0.013
cell death GO:0008219 121 0.013
axon development GO:0061564 166 0.013
response to alkaloid GO:0043279 2 0.013
rna polyadenylation GO:0043631 2 0.013
apoptotic process GO:0006915 116 0.013
cellular response to nutrient levels GO:0031669 2 0.013
determination of ventral identity GO:0048264 21 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
phototransduction GO:0007602 2 0.013
negative regulation of metabolic process GO:0009892 86 0.013
monovalent inorganic cation transport GO:0015672 42 0.012
carbohydrate homeostasis GO:0033500 1 0.012
cellular localization GO:0051641 97 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
central nervous system development GO:0007417 387 0.012
vasculature development GO:0001944 278 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
cell motility GO:0048870 244 0.012
stem cell fate commitment GO:0048865 1 0.012
meiotic chromosome segregation GO:0045132 3 0.012
chemosensory behavior GO:0007635 1 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
triglyceride homeostasis GO:0070328 2 0.012
vesicle mediated transport GO:0016192 22 0.012
developmental growth involved in morphogenesis GO:0060560 86 0.012
oxidation reduction process GO:0055114 41 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
protein modification process GO:0036211 100 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
bmp signaling pathway GO:0030509 52 0.012
regulation of multicellular organism growth GO:0040014 4 0.012
cellular amine metabolic process GO:0044106 2 0.012
regulation of circadian rhythm GO:0042752 4 0.012
regulation of phosphorus metabolic process GO:0051174 43 0.012
head development GO:0060322 303 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
regulation of gtpase activity GO:0043087 2 0.012
regulation of developmental process GO:0050793 247 0.012
phosphorylation GO:0016310 69 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
spindle assembly involved in mitosis GO:0090307 1 0.012
negative regulation of defense response GO:0031348 2 0.012
calcium ion import GO:0070509 4 0.012
germ line stem cell division GO:0042078 1 0.012
macromolecule modification GO:0043412 111 0.012
positive regulation of cell division GO:0051781 2 0.011
multicellular organism growth GO:0035264 4 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
cellular component disassembly GO:0022411 1 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
epidermal cell fate specification GO:0009957 4 0.011
nucleotide metabolic process GO:0009117 28 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
cation transport GO:0006812 81 0.011
cellular component biogenesis GO:0044085 178 0.011
regulation of tube size GO:0035150 2 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
mechanosensory behavior GO:0007638 2 0.011
gtp metabolic process GO:0046039 4 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.011
single organism membrane fusion GO:0044801 2 0.011
cellular response to starvation GO:0009267 1 0.011
single organism transport GO:0044765 206 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
chromosome organization involved in meiosis GO:0070192 1 0.011
blood circulation GO:0008015 87 0.011
cellular response to estrogen stimulus GO:0071391 24 0.011
hormone secretion GO:0046879 2 0.011
striated muscle cell development GO:0055002 108 0.011
cellular response to oxygen containing compound GO:1901701 20 0.011
negative regulation of translation GO:0017148 1 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
organelle organization GO:0006996 227 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
killing of cells of other organism GO:0031640 1 0.011
lipid catabolic process GO:0016042 4 0.011
immunoglobulin mediated immune response GO:0016064 3 0.011
axonogenesis GO:0007409 152 0.011
embryonic organ development GO:0048568 381 0.011
modification dependent protein catabolic process GO:0019941 3 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
protein polyubiquitination GO:0000209 4 0.010
positive regulation of multi organism process GO:0043902 3 0.010
glucose homeostasis GO:0042593 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
response to radiation GO:0009314 51 0.010
developmental cell growth GO:0048588 52 0.010
positive regulation of biosynthetic process GO:0009891 68 0.010
regulation of cell death GO:0010941 103 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
regulation of catalytic activity GO:0050790 55 0.010
response to antibiotic GO:0046677 1 0.010
somatic stem cell maintenance GO:0035019 1 0.010
organelle fusion GO:0048284 3 0.010
cellular component movement GO:0006928 335 0.010
viral process GO:0016032 1 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
cellular response to endogenous stimulus GO:0071495 68 0.010

mkrn4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
disease of metabolism DOID:0014667 0 0.021
inherited metabolic disorder DOID:655 0 0.021
lysosomal storage disease DOID:3211 0 0.017
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011