Danio rerio

0 known processes

mchr1b

melanin-concentrating hormone receptor 1b

(Aliases: gpr24b)

mchr1b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cyclic nucleotide metabolic process GO:0030800 7 0.709
regulation of camp metabolic process GO:0030814 9 0.684
g protein coupled receptor signaling pathway GO:0007186 74 0.611
Zebrafish Fly
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.549
organic cyclic compound metabolic process GO:1901360 301 0.443
Zebrafish
organophosphate biosynthetic process GO:0090407 23 0.421
purine ribonucleotide biosynthetic process GO:0009152 20 0.403
heterocycle metabolic process GO:0046483 290 0.392
Zebrafish
negative regulation of cyclase activity GO:0031280 6 0.375
regulation of cellular biosynthetic process GO:0031326 245 0.349
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.343
Zebrafish
regulation of camp biosynthetic process GO:0030817 9 0.322
cellular nitrogen compound metabolic process GO:0034641 290 0.287
Zebrafish
ribonucleotide biosynthetic process GO:0009260 20 0.283
negative regulation of hormone secretion GO:0046888 2 0.278
positive regulation of camp biosynthetic process GO:0030819 2 0.277
nucleobase containing compound metabolic process GO:0006139 274 0.276
Zebrafish
negative regulation of metabolic process GO:0009892 86 0.273
signal transduction GO:0007165 455 0.266
Zebrafish Fly
regulation of macromolecule metabolic process GO:0060255 317 0.218
Zebrafish
response to chemical GO:0042221 320 0.217
regulation of signaling GO:0023051 235 0.216
response to external stimulus GO:0009605 264 0.214
nucleoside phosphate biosynthetic process GO:1901293 21 0.213
carbohydrate derivative biosynthetic process GO:1901137 43 0.199
maintenance of location GO:0051235 4 0.199
cell surface receptor signaling pathway GO:0007166 325 0.196
Zebrafish Fly
ribose phosphate biosynthetic process GO:0046390 20 0.194
cellular aromatic compound metabolic process GO:0006725 295 0.186
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.180
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.172
Zebrafish
sensory organ development GO:0007423 393 0.172
negative regulation of nucleotide biosynthetic process GO:0030809 7 0.164
eye development GO:0001654 277 0.161
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.157
negative regulation of cellular process GO:0048523 283 0.153
cognition GO:0050890 1 0.147
nitric oxide biosynthetic process GO:0006809 2 0.146
regulation of purine nucleotide metabolic process GO:1900542 17 0.145
multicellular organism growth GO:0035264 4 0.144
regulation of cellular metabolic process GO:0031323 320 0.141
Zebrafish
regulation of multicellular organism growth GO:0040014 4 0.140
regulation of cell communication GO:0010646 232 0.138
peptide transport GO:0015833 1 0.137
regulation of primary metabolic process GO:0080090 311 0.136
Zebrafish
single organism transport GO:0044765 206 0.135
phosphate containing compound metabolic process GO:0006796 108 0.134
circadian sleep wake cycle process GO:0022410 2 0.131
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.131
camera type eye development GO:0043010 222 0.129
purine nucleotide biosynthetic process GO:0006164 20 0.128
negative regulation of nucleotide metabolic process GO:0045980 7 0.122
nucleic acid metabolic process GO:0090304 244 0.121
Zebrafish
nucleotide biosynthetic process GO:0009165 21 0.120
regulation of adenylate cyclase activity GO:0045761 6 0.118
purine containing compound biosynthetic process GO:0072522 20 0.117
ion transport GO:0006811 114 0.116
negative regulation of purine nucleotide biosynthetic process GO:1900372 7 0.110
nucleobase containing compound biosynthetic process GO:0034654 205 0.107
Zebrafish
organonitrogen compound biosynthetic process GO:1901566 47 0.103
regulation of ion transmembrane transporter activity GO:0032412 2 0.102
regulation of response to stimulus GO:0048583 269 0.099
tube morphogenesis GO:0035239 349 0.099
locomotion GO:0040011 313 0.096
regulation of hormone secretion GO:0046883 2 0.095
cyclic purine nucleotide metabolic process GO:0052652 18 0.093
regulation of biosynthetic process GO:0009889 250 0.092
Zebrafish
purine ribonucleotide metabolic process GO:0009150 27 0.089
stem cell proliferation GO:0072089 4 0.087
smooth muscle contraction GO:0006939 2 0.084
positive regulation of cell cycle GO:0045787 3 0.080
cyclic nucleotide biosynthetic process GO:0009190 18 0.080
regulation of metabolic process GO:0019222 359 0.080
Zebrafish
hormone transport GO:0009914 2 0.079
regulation of nucleotide biosynthetic process GO:0030808 15 0.077
negative regulation of purine nucleotide metabolic process GO:1900543 7 0.077
camp biosynthetic process GO:0006171 11 0.075
nucleobase containing small molecule metabolic process GO:0055086 32 0.074
cyclic nucleotide metabolic process GO:0009187 18 0.074
small molecule metabolic process GO:0044281 77 0.073
regulation of circadian sleep wake cycle GO:0042749 1 0.073
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 5 0.073
aromatic compound biosynthetic process GO:0019438 217 0.072
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.071
Zebrafish
gabaergic neuron differentiation GO:0097154 2 0.069
cellular component movement GO:0006928 335 0.069
negative regulation of secretion by cell GO:1903531 2 0.068
negative regulation of cellular metabolic process GO:0031324 77 0.068
morphogenesis of an epithelium GO:0002009 333 0.067
hormone secretion GO:0046879 2 0.066
gene expression GO:0010467 252 0.064
Zebrafish
regulation of signal transduction GO:0009966 225 0.063
nitric oxide metabolic process GO:0046209 2 0.062
establishment of localization GO:0051234 244 0.061
circadian sleep wake cycle sleep GO:0050802 1 0.058
muscle structure development GO:0061061 196 0.057
circadian sleep wake cycle GO:0042745 2 0.055
positive regulation of cell communication GO:0010647 56 0.054
transport GO:0006810 220 0.054
camp metabolic process GO:0046058 11 0.054
aging GO:0007568 2 0.054
rna metabolic process GO:0016070 219 0.053
Zebrafish
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 7 0.053
development of primary female sexual characteristics GO:0046545 4 0.052
adrenergic receptor signaling pathway GO:0071875 5 0.051
organonitrogen compound metabolic process GO:1901564 74 0.051
negative regulation of camp biosynthetic process GO:0030818 7 0.051
single organism biosynthetic process GO:0044711 71 0.050
regulation of multicellular organismal process GO:0051239 277 0.049
brain development GO:0007420 293 0.049
cellular nitrogen compound biosynthetic process GO:0044271 218 0.048
Zebrafish
regulation of biological quality GO:0065008 263 0.048
energy reserve metabolic process GO:0006112 2 0.047
regulation of nitrogen compound metabolic process GO:0051171 251 0.047
Zebrafish
embryonic limb morphogenesis GO:0030326 2 0.046
regulation of nucleotide metabolic process GO:0006140 17 0.046
regulation of nucleic acid templated transcription GO:1903506 213 0.045
Zebrafish
lipid storage GO:0019915 1 0.045
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.044
negative regulation of catalytic activity GO:0043086 21 0.043
positive regulation of stem cell proliferation GO:2000648 1 0.043
macromolecule biosynthetic process GO:0009059 227 0.041
Zebrafish
enzyme linked receptor protein signaling pathway GO:0007167 106 0.041
carbohydrate derivative metabolic process GO:1901135 61 0.041
developmental growth GO:0048589 166 0.040
cellular response to radiation GO:0071478 4 0.040
dorsal ventral pattern formation GO:0009953 125 0.040
negative regulation of biological process GO:0048519 304 0.039
female sex differentiation GO:0046660 4 0.039
programmed cell death GO:0012501 119 0.039
biosynthetic process GO:0009058 294 0.038
Zebrafish
regulation of cytokine production GO:0001817 3 0.038
reactive oxygen species biosynthetic process GO:1903409 1 0.037
regulation of lyase activity GO:0051339 12 0.037
single organism organelle organization GO:1902589 199 0.037
transcription from rna polymerase ii promoter GO:0006366 80 0.036
regulation of gene expression GO:0010468 265 0.036
Zebrafish
regulation of molecular function GO:0065009 70 0.035
cell migration GO:0016477 237 0.035
positive regulation of cellular component biogenesis GO:0044089 3 0.035
release of sequestered calcium ion into cytosol GO:0051209 3 0.034
embryonic organ development GO:0048568 381 0.034
negative regulation of response to stimulus GO:0048585 104 0.034
regulation of catalytic activity GO:0050790 55 0.034
positive regulation of cellular catabolic process GO:0031331 3 0.034
sleep GO:0030431 1 0.034
localization of cell GO:0051674 244 0.033
regulation of circadian rhythm GO:0042752 4 0.033
female gonad development GO:0008585 4 0.032
neural tube patterning GO:0021532 33 0.032
organic acid metabolic process GO:0006082 31 0.032
divalent inorganic cation homeostasis GO:0072507 22 0.032
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.032
regulation of transcription dna templated GO:0006355 213 0.031
Zebrafish
regulation of stem cell proliferation GO:0072091 2 0.031
single organism metabolic process GO:0044710 217 0.031
negative regulation of lyase activity GO:0051350 6 0.031
cell part morphogenesis GO:0032990 246 0.030
sensory perception of pain GO:0019233 1 0.030
positive regulation of catabolic process GO:0009896 4 0.030
positive regulation of map kinase activity GO:0043406 3 0.030
negative regulation of cellular biosynthetic process GO:0031327 55 0.030
opioid receptor signaling pathway GO:0038003 3 0.029
Zebrafish
circulatory system process GO:0003013 87 0.029
system process GO:0003008 185 0.028
regulation of cell death GO:0010941 103 0.028
organophosphate metabolic process GO:0019637 37 0.028
regulation of cyclase activity GO:0031279 12 0.028
wound healing GO:0042060 90 0.027
embryonic organ morphogenesis GO:0048562 274 0.027
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.026
Zebrafish
blood circulation GO:0008015 87 0.026
cartilage development GO:0051216 96 0.026
negative regulation of adenylate cyclase activity GO:0007194 6 0.026
multicellular organismal homeostasis GO:0048871 29 0.025
reactive nitrogen species metabolic process GO:2001057 0 0.025
homeostatic process GO:0042592 142 0.025
negative regulation of molecular function GO:0044092 23 0.025
neuron projection development GO:0031175 180 0.025
cellular amide metabolic process GO:0043603 4 0.025
regulation of phosphate metabolic process GO:0019220 43 0.024
regulation of programmed cell death GO:0043067 101 0.024
cell motility GO:0048870 244 0.024
regulation of fatty acid beta oxidation GO:0031998 1 0.024
phosphorus metabolic process GO:0006793 109 0.024
regulation of phosphorus metabolic process GO:0051174 43 0.024
regulation of reactive oxygen species metabolic process GO:2000377 2 0.024
negative regulation of camp metabolic process GO:0030815 7 0.023
erk1 and erk2 cascade GO:0070371 4 0.023
neuron differentiation GO:0030182 353 0.023
response to topologically incorrect protein GO:0035966 2 0.023
intracellular signal transduction GO:0035556 85 0.023
positive regulation of biological process GO:0048518 253 0.023
Zebrafish
negative regulation of oocyte development GO:0060283 2 0.023
regulation of nucleotide catabolic process GO:0030811 2 0.022
organelle organization GO:0006996 227 0.022
regulation of dendrite development GO:0050773 3 0.022
positive regulation of cellular process GO:0048522 201 0.022
Zebrafish
glial cell migration GO:0008347 3 0.022
regulation of transporter activity GO:0032409 2 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.022
regulation of response to oxidative stress GO:1902882 2 0.022
positive regulation of camp metabolic process GO:0030816 2 0.022
negative regulation of biosynthetic process GO:0009890 55 0.022
generation of neurons GO:0048699 385 0.022
carbohydrate biosynthetic process GO:0016051 1 0.022
ribonucleotide metabolic process GO:0009259 27 0.021
chemotaxis GO:0006935 104 0.021
cellular biosynthetic process GO:0044249 286 0.021
Zebrafish
multicellular organismal response to stress GO:0033555 2 0.021
head development GO:0060322 303 0.021
metal ion transport GO:0030001 58 0.021
regulation of blood circulation GO:1903522 32 0.021
fatty acid transport GO:0015908 1 0.021
long chain fatty acid transport GO:0015909 1 0.021
regulation of transmembrane transporter activity GO:0022898 2 0.020
cellular macromolecule metabolic process GO:0044260 391 0.020
Zebrafish
spinal cord development GO:0021510 46 0.020
nucleoside phosphate metabolic process GO:0006753 28 0.020
axon guidance GO:0007411 86 0.020
purine containing compound metabolic process GO:0072521 29 0.020
cation transport GO:0006812 81 0.020
small gtpase mediated signal transduction GO:0007264 8 0.020
glucose homeostasis GO:0042593 1 0.020
regulation of cellular component organization GO:0051128 86 0.020
regulation of fatty acid metabolic process GO:0019217 1 0.020
transmembrane transport GO:0055085 120 0.019
regulation of tube size GO:0035150 2 0.019
regulation of protein complex assembly GO:0043254 3 0.019
positive regulation of signaling GO:0023056 56 0.019
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 8 0.019
cell projection organization GO:0030030 284 0.019
regulation of hydrolase activity GO:0051336 28 0.019
heart contraction GO:0060047 71 0.018
protein complex assembly GO:0006461 30 0.018
wnt signaling pathway GO:0016055 80 0.018
regulation of system process GO:0044057 40 0.018
mechanosensory behavior GO:0007638 2 0.018
nuclear transport GO:0051169 4 0.018
oxoacid metabolic process GO:0043436 31 0.017
negative regulation of feeding behavior GO:2000252 2 0.017
positive regulation of catalytic activity GO:0043085 25 0.017
gtp catabolic process GO:0006184 2 0.017
sensory perception of chemical stimulus GO:0007606 3 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.017
neuromuscular synaptic transmission GO:0007274 2 0.017
regulation of intracellular signal transduction GO:1902531 57 0.017
negative regulation of signaling GO:0023057 96 0.017
meiotic nuclear division GO:0007126 4 0.017
axon development GO:0061564 166 0.017
negative regulation of secretion GO:0051048 2 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
regulation of protein metabolic process GO:0051246 56 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
metal ion homeostasis GO:0055065 26 0.016
striated muscle cell differentiation GO:0051146 129 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
regulation of blood vessel size GO:0050880 2 0.016
regulation of reproductive process GO:2000241 4 0.016
response to radiation GO:0009314 51 0.016
amide transport GO:0042886 12 0.016
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.016
carbohydrate homeostasis GO:0033500 1 0.016
positive regulation of gtp catabolic process GO:0033126 1 0.016
mapk cascade GO:0000165 18 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
connective tissue development GO:0061448 99 0.015
positive regulation of bmp signaling pathway GO:0030513 10 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.015
negative regulation of catabolic process GO:0009895 3 0.015
neuron development GO:0048666 262 0.015
fourth ventricle development GO:0021592 8 0.015
oocyte maturation GO:0001556 4 0.015
macromolecular complex subunit organization GO:0043933 74 0.014
cellular ketone metabolic process GO:0042180 11 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
cellular response to endogenous stimulus GO:0071495 68 0.014
inner ear development GO:0048839 126 0.014
hemopoiesis GO:0030097 183 0.014
urogenital system development GO:0001655 97 0.014
skeletal system development GO:0001501 181 0.014
diencephalon development GO:0021536 58 0.014
transcription dna templated GO:0006351 181 0.014
Zebrafish
renal system development GO:0072001 94 0.014
tissue remodeling GO:0048771 4 0.014
negative regulation of phosphate metabolic process GO:0045936 13 0.014
cellular response to hormone stimulus GO:0032870 39 0.013
organic substance biosynthetic process GO:1901576 289 0.013
Zebrafish
regulation of neurological system process GO:0031644 2 0.013
larval development GO:0002164 2 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
response to wounding GO:0009611 116 0.013
cell morphogenesis GO:0000902 289 0.013
spemann organizer formation at the embryonic shield GO:0060063 2 0.013
protein metabolic process GO:0019538 183 0.013
neurological system process GO:0050877 62 0.013
regulation of behavior GO:0050795 24 0.013
regulation of hormone levels GO:0010817 21 0.013
regulation of blood pressure GO:0008217 1 0.013
divalent inorganic cation transport GO:0072511 21 0.013
regulation of heart contraction GO:0008016 32 0.013
ion transmembrane transport GO:0034220 91 0.013
single organism behavior GO:0044708 24 0.013
ovulation cycle process GO:0022602 2 0.013
macromolecule modification GO:0043412 111 0.013
regulation of dna replication GO:0006275 3 0.012
protein targeting to nucleus GO:0044744 3 0.012
protein modification process GO:0036211 100 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
Zebrafish
endoplasmic reticulum unfolded protein response GO:0030968 2 0.012
positive regulation of phosphorus metabolic process GO:0010562 21 0.012
single organism localization GO:1902578 225 0.012
regulation of protein depolymerization GO:1901879 1 0.012
cellular response to nutrient levels GO:0031669 2 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
chondroitin sulfate metabolic process GO:0030204 2 0.012
cell proliferation GO:0008283 80 0.012
nucleotide metabolic process GO:0009117 28 0.012
positive regulation of transport GO:0051050 2 0.012
regulation of ion transmembrane transport GO:0034765 18 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
Zebrafish
fatty acid catabolic process GO:0009062 1 0.012
positive regulation of cell division GO:0051781 2 0.012
regulation of localization GO:0032879 104 0.012
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.012
response to glucocorticoid GO:0051384 1 0.012
striated muscle cell development GO:0055002 108 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
bone remodeling GO:0046849 2 0.012
phosphorylation GO:0016310 69 0.012
specification of symmetry GO:0009799 204 0.012
regulation of metal ion transport GO:0010959 4 0.011
skeletal system morphogenesis GO:0048705 102 0.011
negative regulation of behavior GO:0048521 6 0.011
optomotor response GO:0071632 1 0.011
regulation of locomotion GO:0040012 55 0.011
cell migration involved in gastrulation GO:0042074 79 0.011
adult behavior GO:0030534 2 0.011
response to metal ion GO:0010038 34 0.011
cellular component assembly GO:0022607 170 0.011
type b pancreatic cell development GO:0003323 4 0.011
heart development GO:0007507 313 0.011
digestive tract development GO:0048565 265 0.011
optic placode formation involved in camera type eye formation GO:0046619 3 0.011
taxis GO:0042330 109 0.011
regulation of endopeptidase activity GO:0052548 23 0.011
cellular localization GO:0051641 97 0.011
cellular amine metabolic process GO:0044106 2 0.011
cellular response to unfolded protein GO:0034620 2 0.011
nucleic acid templated transcription GO:0097659 181 0.011
Zebrafish
cell proliferation involved in heart morphogenesis GO:0061323 2 0.011
response to uv GO:0009411 3 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
growth GO:0040007 174 0.011
regulation of gtpase activity GO:0043087 2 0.011
gland development GO:0048732 143 0.011
response to abiotic stimulus GO:0009628 122 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
monoamine transport GO:0015844 1 0.011
cellular response to toxic substance GO:0097237 1 0.010
neuroblast proliferation GO:0007405 2 0.010
synaptic transmission GO:0007268 35 0.010
Zebrafish
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.010
regulation of synapse organization GO:0050807 3 0.010
gtp metabolic process GO:0046039 4 0.010
neuron apoptotic process GO:0051402 20 0.010
positive regulation of myeloid cell differentiation GO:0045639 2 0.010
establishment of localization in cell GO:0051649 77 0.010
regionalization GO:0003002 274 0.010
negative regulation of nuclear division GO:0051784 3 0.010
determination of dorsal ventral asymmetry GO:0048262 34 0.010
organic substance transport GO:0071702 58 0.010
negative regulation of phosphorus metabolic process GO:0010563 13 0.010

mchr1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.074
acquired metabolic disease DOID:0060158 0 0.020
bone development disease DOID:0080006 0 0.016
bone disease DOID:0080001 0 0.016
disease of anatomical entity DOID:7 0 0.016
dysostosis DOID:1934 0 0.016
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016
synostosis DOID:11971 0 0.016
reproductive system disease DOID:15 0 0.012