Danio rerio

18 known processes

pgam2

phosphoglycerate mutase 2 (muscle)

(Aliases: zgc:63876,MGC63876,MGC174062)

pgam2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nitrogen compound metabolic process GO:0006807 319 0.310
larval development GO:0002164 2 0.284
regulation of biological quality GO:0065008 263 0.212
actomyosin structure organization GO:0031032 53 0.162
positive regulation of nucleoside metabolic process GO:0045979 1 0.154
actin filament based movement GO:0030048 1 0.132
cellular biosynthetic process GO:0044249 286 0.128
fatty acid beta oxidation GO:0006635 1 0.128
single organism metabolic process GO:0044710 217 0.125
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.124
organelle localization GO:0051640 49 0.123
phosphorus metabolic process GO:0006793 109 0.122
small molecule metabolic process GO:0044281 77 0.115
Mouse
glucose homeostasis GO:0042593 1 0.113
actin filament based process GO:0030029 64 0.113
striated muscle cell differentiation GO:0051146 129 0.112
organic substance catabolic process GO:1901575 28 0.111
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.110
cellular component biogenesis GO:0044085 178 0.104
single organism transport GO:0044765 206 0.102
cellular component morphogenesis GO:0032989 336 0.101
regulation of ion transmembrane transporter activity GO:0032412 2 0.101
nucleobase containing compound metabolic process GO:0006139 274 0.100
locomotion GO:0040011 313 0.099
cellular aromatic compound metabolic process GO:0006725 295 0.098
single organism organelle organization GO:1902589 199 0.093
striated muscle cell development GO:0055002 108 0.093
organic cyclic compound metabolic process GO:1901360 301 0.089
regulation of cellular metabolic process GO:0031323 320 0.088
regulation of nucleoside metabolic process GO:0009118 2 0.087
single organism localization GO:1902578 225 0.083
sensory organ development GO:0007423 393 0.078
organelle organization GO:0006996 227 0.076
establishment of localization GO:0051234 244 0.074
nucleoside biosynthetic process GO:0009163 2 0.073
nucleoside monophosphate catabolic process GO:0009125 4 0.073
regionalization GO:0003002 274 0.072
homeostatic process GO:0042592 142 0.071
muscle cell differentiation GO:0042692 139 0.070
regulation of cell matrix adhesion GO:0001952 1 0.068
cytoskeleton organization GO:0007010 96 0.067
positive regulation of catabolic process GO:0009896 4 0.067
aging GO:0007568 2 0.065
mitochondrion organization GO:0007005 4 0.064
transport GO:0006810 220 0.064
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.063
regulation of metal ion transport GO:0010959 4 0.061
cellular nitrogen compound biosynthetic process GO:0044271 218 0.060
cellular nitrogen compound metabolic process GO:0034641 290 0.060
neuron differentiation GO:0030182 353 0.059
organelle assembly GO:0070925 110 0.059
tube morphogenesis GO:0035239 349 0.058
cell substrate adhesion GO:0031589 4 0.057
cellular component assembly GO:0022607 170 0.055
heart development GO:0007507 313 0.055
establishment of organelle localization GO:0051656 45 0.053
regulation of multicellular organismal process GO:0051239 277 0.053
ubiquitin dependent protein catabolic process GO:0006511 3 0.052
positive regulation of cellular catabolic process GO:0031331 3 0.052
purine ribonucleoside biosynthetic process GO:0046129 2 0.052
adult behavior GO:0030534 2 0.051
regulation of calcium ion transport GO:0051924 2 0.051
regulation of striated muscle contraction GO:0006942 2 0.050
cellular component movement GO:0006928 335 0.050
synaptic growth at neuromuscular junction GO:0051124 2 0.049
nucleobase containing compound biosynthetic process GO:0034654 205 0.048
heterocycle metabolic process GO:0046483 290 0.048
embryonic organ development GO:0048568 381 0.047
cellular respiration GO:0045333 3 0.047
organic acid metabolic process GO:0006082 31 0.047
Mouse
morphogenesis of an epithelium GO:0002009 333 0.046
behavior GO:0007610 74 0.045
regulation of purine nucleotide catabolic process GO:0033121 2 0.045
digestive tract development GO:0048565 265 0.044
establishment of localization in cell GO:0051649 77 0.044
response to stress GO:0006950 263 0.044
organophosphate metabolic process GO:0019637 37 0.043
carbohydrate homeostasis GO:0033500 1 0.043
pyruvate metabolic process GO:0006090 1 0.042
Mouse
cell cell signaling GO:0007267 52 0.041
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.041
ribonucleotide biosynthetic process GO:0009260 20 0.041
organic substance biosynthetic process GO:1901576 289 0.041
peptide transport GO:0015833 1 0.040
organic cyclic compound biosynthetic process GO:1901362 223 0.040
regulation of protein polymerization GO:0032271 2 0.040
neuron development GO:0048666 262 0.040
small molecule catabolic process GO:0044282 3 0.040
response to external stimulus GO:0009605 264 0.039
regulation of transmembrane transporter activity GO:0022898 2 0.039
growth GO:0040007 174 0.038
catabolic process GO:0009056 32 0.038
Mouse
regulation of reproductive process GO:2000241 4 0.038
cell projection organization GO:0030030 284 0.038
adherens junction organization GO:0034332 4 0.038
muscle cell cellular homeostasis GO:0046716 5 0.037
somitogenesis GO:0001756 87 0.037
intestinal absorption GO:0050892 2 0.037
positive regulation of cellular process GO:0048522 201 0.036
regulation of nucleotide catabolic process GO:0030811 2 0.036
p38mapk cascade GO:0038066 1 0.036
organonitrogen compound metabolic process GO:1901564 74 0.036
regulation of cellular biosynthetic process GO:0031326 245 0.035
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.035
segmentation GO:0035282 97 0.035
blood circulation GO:0008015 87 0.034
cellular localization GO:0051641 97 0.034
regulation of metabolic process GO:0019222 359 0.034
microtubule based process GO:0007017 60 0.034
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.033
purine containing compound biosynthetic process GO:0072522 20 0.033
signal transduction GO:0007165 455 0.032
carboxylic acid metabolic process GO:0019752 22 0.032
Mouse
regulation of membrane potential GO:0042391 23 0.031
guanosine containing compound metabolic process GO:1901068 4 0.031
determination of bilateral symmetry GO:0009855 204 0.031
cellular amino acid biosynthetic process GO:0008652 2 0.031
heterocycle biosynthetic process GO:0018130 215 0.030
developmental growth GO:0048589 166 0.030
anterior posterior pattern specification GO:0009952 152 0.029
purine nucleoside monophosphate catabolic process GO:0009128 4 0.029
anatomical structure homeostasis GO:0060249 36 0.029
maintenance of location GO:0051235 4 0.029
notochord development GO:0030903 54 0.029
purine ribonucleotide biosynthetic process GO:0009152 20 0.028
cell morphogenesis GO:0000902 289 0.028
negative regulation of blood circulation GO:1903523 2 0.027
muscle cell development GO:0055001 115 0.027
eye development GO:0001654 277 0.027
regulation of ion transmembrane transport GO:0034765 18 0.027
regulation of cell shape GO:0008360 1 0.027
positive regulation of secretion GO:0051047 1 0.027
purine nucleotide metabolic process GO:0006163 27 0.026
oxoacid metabolic process GO:0043436 31 0.026
Mouse
regulation of behavior GO:0050795 24 0.026
cellular response to chemical stimulus GO:0070887 157 0.026
purine nucleoside biosynthetic process GO:0042451 2 0.026
organonitrogen compound biosynthetic process GO:1901566 47 0.026
nucleobase containing small molecule metabolic process GO:0055086 32 0.026
phosphate containing compound metabolic process GO:0006796 108 0.026
neuromuscular synaptic transmission GO:0007274 2 0.026
organic acid catabolic process GO:0016054 3 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
nucleoside triphosphate biosynthetic process GO:0009142 2 0.025
chordate embryonic development GO:0043009 271 0.025
neuron projection development GO:0031175 180 0.023
taxis GO:0042330 109 0.023
rhombomere 5 development GO:0021571 4 0.023
regulation of localization GO:0032879 104 0.023
cell matrix adhesion GO:0007160 4 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
embryonic organ morphogenesis GO:0048562 274 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.022
regulation of primary metabolic process GO:0080090 311 0.022
regulation of signaling GO:0023051 235 0.022
positive regulation of transport GO:0051050 2 0.022
response to chemical GO:0042221 320 0.022
digestive system development GO:0055123 289 0.022
hormone transport GO:0009914 2 0.022
regulation of cell substrate adhesion GO:0010810 1 0.022
potassium ion transmembrane transport GO:0071805 10 0.022
ribonucleoside biosynthetic process GO:0042455 2 0.021
multi organism reproductive process GO:0044703 36 0.021
axon development GO:0061564 166 0.021
nucleoside phosphate metabolic process GO:0006753 28 0.021
carbohydrate derivative biosynthetic process GO:1901137 43 0.021
somite development GO:0061053 96 0.021
stem cell differentiation GO:0048863 117 0.021
cellular nitrogen compound catabolic process GO:0044270 15 0.021
muscle system process GO:0003012 20 0.021
regulation of muscle contraction GO:0006937 3 0.021
cellular component disassembly GO:0022411 1 0.020
single organism biosynthetic process GO:0044711 71 0.020
circulatory system process GO:0003013 87 0.020
actin cytoskeleton organization GO:0030036 63 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
nucleic acid metabolic process GO:0090304 244 0.020
nucleobase containing compound transport GO:0015931 2 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.020
negative regulation of cellular process GO:0048523 283 0.019
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
regulation of macromolecule biosynthetic process GO:0010556 225 0.019
calcium mediated signaling GO:0019722 2 0.019
transmembrane transport GO:0055085 120 0.019
hormone secretion GO:0046879 2 0.019
regulation of cardiac muscle contraction GO:0055117 2 0.019
axonogenesis GO:0007409 152 0.019
central nervous system development GO:0007417 387 0.019
actin mediated cell contraction GO:0070252 1 0.019
regulation of actin filament based movement GO:1903115 1 0.019
atp catabolic process GO:0006200 4 0.018
nucleobase containing compound catabolic process GO:0034655 15 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
mesoderm development GO:0007498 88 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 9 0.017
apoptotic process GO:0006915 116 0.017
cell part morphogenesis GO:0032990 246 0.017
cellular response to stress GO:0033554 62 0.017
stem cell proliferation GO:0072089 4 0.017
single organism cellular localization GO:1902580 46 0.017
multicellular organismal reproductive process GO:0048609 35 0.017
muscle structure development GO:0061061 196 0.017
ribose phosphate biosynthetic process GO:0046390 20 0.017
positive regulation of biological process GO:0048518 253 0.017
cellular carbohydrate metabolic process GO:0044262 4 0.017
tissue regeneration GO:0042246 74 0.017
regulation of system process GO:0044057 40 0.017
response to abiotic stimulus GO:0009628 122 0.017
heart morphogenesis GO:0003007 156 0.016
regulation of nucleotide biosynthetic process GO:0030808 15 0.016
reproduction GO:0000003 40 0.016
modification dependent macromolecule catabolic process GO:0043632 3 0.016
sensory organ morphogenesis GO:0090596 200 0.015
organic substance transport GO:0071702 58 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
body morphogenesis GO:0010171 16 0.015
muscle tissue development GO:0060537 110 0.015
myeloid cell homeostasis GO:0002262 56 0.015
hematopoietic or lymphoid organ development GO:0048534 191 0.015
endoplasmic reticulum unfolded protein response GO:0030968 2 0.015
action potential GO:0001508 19 0.015
protein localization to nucleus GO:0034504 3 0.015
protein polymerization GO:0051258 4 0.015
rhombomere 6 development GO:0021572 4 0.015
cellular response to unfolded protein GO:0034620 2 0.015
synaptic transmission GO:0007268 35 0.015
positive regulation of nucleotide biosynthetic process GO:0030810 8 0.014
wound healing GO:0042060 90 0.014
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.014
cation homeostasis GO:0055080 33 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
system process GO:0003008 185 0.014
specification of organ axis polarity GO:0010084 2 0.014
camera type eye development GO:0043010 222 0.014
rna metabolic process GO:0016070 219 0.014
hemopoiesis GO:0030097 183 0.014
purine containing compound metabolic process GO:0072521 29 0.014
regulation of phosphorus metabolic process GO:0051174 43 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
regulation of rna metabolic process GO:0051252 224 0.014
synaptic vesicle transport GO:0048489 1 0.014
purine nucleotide biosynthetic process GO:0006164 20 0.014
monovalent inorganic cation transport GO:0015672 42 0.014
neurotransmitter transport GO:0006836 2 0.014
regulation of gtpase activity GO:0043087 2 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
negative regulation of cell death GO:0060548 60 0.013
inorganic cation transmembrane transport GO:0098662 50 0.013
single organism nuclear import GO:1902593 3 0.013
ion homeostasis GO:0050801 41 0.013
multi organism process GO:0051704 134 0.013
sarcomere organization GO:0045214 26 0.013
muscle organ development GO:0007517 101 0.013
lipid digestion GO:0044241 3 0.013
regulation of hormone secretion GO:0046883 2 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
protein import GO:0017038 3 0.013
plasma membrane repair GO:0001778 2 0.013
cellular response to external stimulus GO:0071496 2 0.013
mitotic cell cycle process GO:1903047 48 0.013
striated muscle contraction GO:0006941 12 0.013
regulation of sodium ion transmembrane transport GO:1902305 1 0.013
microtubule cytoskeleton organization GO:0000226 33 0.013
phagocytosis GO:0006909 3 0.013
regulation of cell communication GO:0010646 232 0.012
single organism catabolic process GO:0044712 13 0.012
Mouse
regulation of response to stimulus GO:0048583 269 0.012
rna biosynthetic process GO:0032774 181 0.012
purine ribonucleotide metabolic process GO:0009150 27 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
regulation of sequestering of calcium ion GO:0051282 4 0.012
regulation of blood vessel size GO:0050880 2 0.012
chemical homeostasis GO:0048878 49 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.012
metal ion homeostasis GO:0055065 26 0.012
gene expression GO:0010467 252 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
retina layer formation GO:0010842 24 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
inorganic ion transmembrane transport GO:0098660 57 0.012
cytokinesis GO:0000910 3 0.012
regulation of transporter activity GO:0032409 2 0.012
cell projection morphogenesis GO:0048858 244 0.012
establishment of protein localization to organelle GO:0072594 4 0.012
regulation of multicellular organism growth GO:0040014 4 0.011
vesicle mediated transport GO:0016192 22 0.011
cell migration GO:0016477 237 0.011
regulation of transmembrane transport GO:0034762 18 0.011
cellular protein catabolic process GO:0044257 4 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
regulation of programmed cell death GO:0043067 101 0.011
synaptic vesicle localization GO:0097479 1 0.011
heterocycle catabolic process GO:0046700 15 0.011
head development GO:0060322 303 0.011
nucleoside metabolic process GO:0009116 11 0.011
generation of neurons GO:0048699 385 0.011
mitochondrial transport GO:0006839 2 0.011
regulation of biosynthetic process GO:0009889 250 0.011
regulation of tube size GO:0035150 2 0.011
striated muscle tissue development GO:0014706 110 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
carbohydrate metabolic process GO:0005975 12 0.011
Mouse
biosynthetic process GO:0009058 294 0.011
response to organic substance GO:0010033 153 0.011
carboxylic acid catabolic process GO:0046395 3 0.011
response to endogenous stimulus GO:0009719 83 0.010
multicellular organism reproduction GO:0032504 35 0.010
determination of left right symmetry GO:0007368 179 0.010
cellular amino acid metabolic process GO:0006520 7 0.010
nucleoside monophosphate biosynthetic process GO:0009124 1 0.010
protein import into nucleus GO:0006606 3 0.010
response to unfolded protein GO:0006986 2 0.010
glycosyl compound metabolic process GO:1901657 11 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
spermatid differentiation GO:0048515 2 0.010
fin regeneration GO:0031101 51 0.010
nucleic acid templated transcription GO:0097659 181 0.010
programmed cell death GO:0012501 119 0.010

pgam2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.080
musculoskeletal system disease DOID:17 0 0.080
immune system disease DOID:2914 0 0.026
hematopoietic system disease DOID:74 0 0.022
anemia DOID:2355 0 0.019
distal arthrogryposis DOID:0050646 0 0.012
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012