Danio rerio

0 known processes

depdc1a

DEP domain containing 1a

(Aliases: MGC55374,cb41,FLJ20354,depdc1,wu:fc05g03,zgc:55374,sb:cb41)

depdc1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spindle assembly involved in mitosis GO:0090307 1 0.495
positive regulation of cell cycle GO:0045787 3 0.344
regulation of nitrogen compound metabolic process GO:0051171 251 0.313
Human
oocyte maturation GO:0001556 4 0.305
microtubule organizing center organization GO:0031023 1 0.226
regulation of purine nucleotide catabolic process GO:0033121 2 0.226
cellular macromolecule metabolic process GO:0044260 391 0.223
Human
cytokinesis GO:0000910 3 0.216
negative regulation of biological process GO:0048519 304 0.214
Human
positive regulation of catabolic process GO:0009896 4 0.206
cytoskeleton dependent cytokinesis GO:0061640 3 0.203
regulation of metabolic process GO:0019222 359 0.200
Human
meiotic cell cycle process GO:1903046 3 0.181
gene expression GO:0010467 252 0.180
Human
regulation of cellular metabolic process GO:0031323 320 0.153
Human
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.152
Human
positive regulation of cellular catabolic process GO:0031331 3 0.147
centrosome organization GO:0051297 1 0.143
regulation of primary metabolic process GO:0080090 311 0.127
Human
centrosome cycle GO:0007098 1 0.126
regulation of microtubule cytoskeleton organization GO:0070507 3 0.113
mitotic cell cycle GO:0000278 64 0.111
negative regulation of cellular process GO:0048523 283 0.110
Human
heterocycle metabolic process GO:0046483 290 0.108
Human
neuron development GO:0048666 262 0.105
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.104
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.103
regulation of protein complex assembly GO:0043254 3 0.100
regulation of nucleoside metabolic process GO:0009118 2 0.099
phagocytosis GO:0006909 3 0.099
meiotic nuclear division GO:0007126 4 0.096
positive regulation of nucleoside metabolic process GO:0045979 1 0.095
stem cell proliferation GO:0072089 4 0.094
negative regulation of protein complex assembly GO:0031333 1 0.088
maintenance of location GO:0051235 4 0.085
guanosine containing compound metabolic process GO:1901068 4 0.085
modification dependent protein catabolic process GO:0019941 3 0.084
modification dependent macromolecule catabolic process GO:0043632 3 0.082
stem cell maintenance GO:0019827 4 0.082
cell cycle GO:0007049 93 0.081
neuroblast proliferation GO:0007405 2 0.080
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.079
regulation of gtp catabolic process GO:0033124 2 0.077
spindle assembly GO:0051225 2 0.076
cell fate commitment GO:0045165 99 0.075
somatic muscle development GO:0007525 4 0.074
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.074
positive regulation of gtp catabolic process GO:0033126 1 0.072
sensory organ morphogenesis GO:0090596 200 0.071
regulation of gene expression GO:0010468 265 0.070
Human
aromatic compound biosynthetic process GO:0019438 217 0.068
Human
nucleobase containing compound biosynthetic process GO:0034654 205 0.066
Human
organic cyclic compound metabolic process GO:1901360 301 0.066
Human
nucleic acid metabolic process GO:0090304 244 0.064
Human
cell cycle g2 m phase transition GO:0044839 4 0.062
regulation of macromolecule metabolic process GO:0060255 317 0.061
Human
regulation of cell cycle GO:0051726 52 0.060
immune system process GO:0002376 241 0.059
regulation of biosynthetic process GO:0009889 250 0.058
Human
larval development GO:0002164 2 0.058
locomotion GO:0040011 313 0.058
multicellular organism growth GO:0035264 4 0.057
nucleobase containing compound metabolic process GO:0006139 274 0.057
Human
nitrogen compound metabolic process GO:0006807 319 0.055
Human
single organism organelle organization GO:1902589 199 0.055
organic substance biosynthetic process GO:1901576 289 0.054
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.054
Human
g2 m transition of mitotic cell cycle GO:0000086 4 0.053
g2 dna damage checkpoint GO:0031572 3 0.053
generation of neurons GO:0048699 385 0.053
organelle organization GO:0006996 227 0.053
cell motility GO:0048870 244 0.053
cell cycle process GO:0022402 53 0.052
negative regulation of cell cycle process GO:0010948 9 0.052
cytoskeleton organization GO:0007010 96 0.052
gtp catabolic process GO:0006184 2 0.051
regulation of gtpase activity GO:0043087 2 0.051
digestive tract development GO:0048565 265 0.051
cellular component movement GO:0006928 335 0.049
protein metabolic process GO:0019538 183 0.048
regulation of cell development GO:0060284 100 0.048
death GO:0016265 121 0.048
gtp metabolic process GO:0046039 4 0.048
signal transduction GO:0007165 455 0.047
positive regulation of nucleotide catabolic process GO:0030813 1 0.046
mitotic dna integrity checkpoint GO:0044774 4 0.046
regulation of protein catabolic process GO:0042176 1 0.045
eye development GO:0001654 277 0.045
regulation of cell communication GO:0010646 232 0.044
biosynthetic process GO:0009058 294 0.044
Human
regulation of nucleic acid templated transcription GO:1903506 213 0.044
Human
regulation of macromolecule biosynthetic process GO:0010556 225 0.044
Human
cytokinetic process GO:0032506 2 0.044
regulation of dendrite development GO:0050773 3 0.043
mitotic cell cycle process GO:1903047 48 0.043
macromolecule modification GO:0043412 111 0.043
sulfur compound transport GO:0072348 3 0.042
retinal rod cell development GO:0046548 4 0.041
guanosine containing compound catabolic process GO:1901069 2 0.040
mitotic cytokinesis GO:0000281 3 0.040
centrosome duplication GO:0051298 1 0.040
cellular protein metabolic process GO:0044267 129 0.040
phosphorus metabolic process GO:0006793 109 0.040
regulation of binding GO:0051098 3 0.040
mitotic g2 m transition checkpoint GO:0044818 3 0.039
regulation of nucleotide catabolic process GO:0030811 2 0.039
cellular biosynthetic process GO:0044249 286 0.039
Human
regulation of cell differentiation GO:0045595 142 0.039
regulation of chromosome segregation GO:0051983 1 0.038
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.038
photoreceptor cell development GO:0042461 40 0.038
cellular component biogenesis GO:0044085 178 0.038
microtubule based process GO:0007017 60 0.038
positive regulation of biological process GO:0048518 253 0.037
multi organism process GO:0051704 134 0.037
regulation of multicellular organism growth GO:0040014 4 0.037
regulation of neurogenesis GO:0050767 87 0.037
negative regulation of catabolic process GO:0009895 3 0.037
cell migration GO:0016477 237 0.036
heterocycle biosynthetic process GO:0018130 215 0.036
Human
neuron differentiation GO:0030182 353 0.036
ubiquitin dependent protein catabolic process GO:0006511 3 0.036
protein import into nucleus GO:0006606 3 0.036
primary neural tube formation GO:0014020 1 0.035
cell death GO:0008219 121 0.035
regulation of protein ubiquitination GO:0031396 3 0.035
regulation of rna metabolic process GO:0051252 224 0.035
Human
regulation of multicellular organismal development GO:2000026 223 0.035
chromosome segregation GO:0007059 12 0.034
nucleic acid templated transcription GO:0097659 181 0.034
Human
regulation of transcription dna templated GO:0006355 213 0.033
Human
protein complex subunit organization GO:0071822 46 0.033
positive regulation of cell division GO:0051781 2 0.033
positive regulation of transport GO:0051050 2 0.033
organic cyclic compound biosynthetic process GO:1901362 223 0.032
Human
stem cell division GO:0017145 1 0.032
macromolecular complex disassembly GO:0032984 1 0.032
regulation of multicellular organismal process GO:0051239 277 0.032
protein complex disassembly GO:0043241 1 0.032
regulation of cell cycle process GO:0010564 20 0.032
microtubule cytoskeleton organization GO:0000226 33 0.032
negative regulation of mitosis GO:0045839 3 0.031
regulation of signaling GO:0023051 235 0.031
homeostatic process GO:0042592 142 0.031
mitotic cell cycle embryonic GO:0045448 2 0.031
regulation of meiotic cell cycle GO:0051445 1 0.031
nuclear division GO:0000280 23 0.031
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.031
Human
regulation of reproductive process GO:2000241 4 0.031
macromolecule biosynthetic process GO:0009059 227 0.031
Human
single organism localization GO:1902578 225 0.030
organelle localization GO:0051640 49 0.030
rna metabolic process GO:0016070 219 0.030
Human
establishment of protein localization to organelle GO:0072594 4 0.030
organelle fission GO:0048285 23 0.030
cell surface receptor signaling pathway GO:0007166 325 0.029
cellular response to chemical stimulus GO:0070887 157 0.029
male meiosis GO:0007140 2 0.029
production of molecular mediator of immune response GO:0002440 2 0.029
transcription dna templated GO:0006351 181 0.029
Human
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.029
digestive system development GO:0055123 289 0.028
intracellular signal transduction GO:0035556 85 0.027
single organism metabolic process GO:0044710 217 0.027
meiosis i GO:0007127 1 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.027
cellular aromatic compound metabolic process GO:0006725 295 0.027
Human
positive regulation of gtpase activity GO:0043547 1 0.026
regulation of protein complex disassembly GO:0043244 1 0.026
developmental growth GO:0048589 166 0.026
regulation of cell shape GO:0008360 1 0.026
meiosis ii GO:0007135 1 0.026
positive regulation of cellular process GO:0048522 201 0.026
regulation of biological quality GO:0065008 263 0.026
phosphorylation GO:0016310 69 0.026
regulation of intracellular protein transport GO:0033157 3 0.025
negative regulation of signal transduction GO:0009968 94 0.025
cellular component morphogenesis GO:0032989 336 0.025
regulation of neural precursor cell proliferation GO:2000177 3 0.025
regulation of cellular biosynthetic process GO:0031326 245 0.025
Human
mitotic metaphase plate congression GO:0007080 1 0.025
growth GO:0040007 174 0.025
female meiotic division GO:0007143 2 0.024
sister chromatid segregation GO:0000819 6 0.024
macromolecular complex assembly GO:0065003 35 0.024
ameboidal type cell migration GO:0001667 143 0.024
protein modification process GO:0036211 100 0.023
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
Human
regulation of neuron differentiation GO:0045664 56 0.023
hematopoietic or lymphoid organ development GO:0048534 191 0.023
mitotic g2 dna damage checkpoint GO:0007095 3 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.023
Human
sulfate transport GO:0008272 2 0.023
regulation of cytoplasmic transport GO:1903649 4 0.023
regulation of localization GO:0032879 104 0.022
neural precursor cell proliferation GO:0061351 20 0.022
negative regulation of nuclear division GO:0051784 3 0.022
cell projection organization GO:0030030 284 0.022
regulation of developmental process GO:0050793 247 0.022
digestive tract morphogenesis GO:0048546 231 0.022
regulation of protein transport GO:0051223 3 0.022
aging GO:0007568 2 0.022
cellular component assembly GO:0022607 170 0.022
regulation of organelle organization GO:0033043 29 0.021
establishment of localization GO:0051234 244 0.021
convergent extension GO:0060026 118 0.021
negative regulation of rna metabolic process GO:0051253 48 0.021
Human
cellular protein catabolic process GO:0044257 4 0.021
cellular protein modification process GO:0006464 100 0.021
cellular component disassembly GO:0022411 1 0.021
macromolecular complex subunit organization GO:0043933 74 0.021
stem cell differentiation GO:0048863 117 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
response to stress GO:0006950 263 0.021
protein polyubiquitination GO:0000209 4 0.020
apoptotic process GO:0006915 116 0.020
regulation of synapse organization GO:0050807 3 0.020
regulation of protein targeting GO:1903533 2 0.020
regulation of signal transduction GO:0009966 225 0.020
chromosome localization GO:0050000 2 0.020
positive regulation of nervous system development GO:0051962 25 0.020
regulation of mitotic cell cycle GO:0007346 25 0.020
regulation of rho protein signal transduction GO:0035023 2 0.020
regulation of cellular component organization GO:0051128 86 0.020
myeloid cell development GO:0061515 32 0.020
nuclear migration GO:0007097 3 0.019
single organism biosynthetic process GO:0044711 71 0.019
regulation of cytoskeleton organization GO:0051493 11 0.019
positive regulation of striated muscle tissue development GO:0045844 1 0.019
regulation of rna biosynthetic process GO:2001141 213 0.019
Human
negative regulation of cell cycle GO:0045786 14 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.018
positive regulation of metabolic process GO:0009893 108 0.018
cell morphogenesis GO:0000902 289 0.018
regulation of oocyte development GO:0060281 3 0.018
eye morphogenesis GO:0048592 144 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
meiotic chromosome segregation GO:0045132 3 0.018
regulation of protein localization to nucleus GO:1900180 2 0.018
cell part morphogenesis GO:0032990 246 0.018
proteasomal protein catabolic process GO:0010498 2 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
protein complex assembly GO:0006461 30 0.017
phosphate containing compound metabolic process GO:0006796 108 0.017
small gtpase mediated signal transduction GO:0007264 8 0.017
negative regulation of cell communication GO:0010648 96 0.017
negative regulation of response to stimulus GO:0048585 104 0.017
protein phosphorylation GO:0006468 47 0.017
immune system development GO:0002520 191 0.017
regulation of molecular function GO:0065009 70 0.017
organelle assembly GO:0070925 110 0.017
ras protein signal transduction GO:0007265 7 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
cell proliferation GO:0008283 80 0.017
cellular amine metabolic process GO:0044106 2 0.017
single organism transport GO:0044765 206 0.017
transport GO:0006810 220 0.016
sexual reproduction GO:0019953 36 0.016
organelle fusion GO:0048284 3 0.016
microtubule depolymerization GO:0007019 1 0.016
germ line stem cell maintenance GO:0030718 2 0.016
neural crest cell development GO:0014032 62 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
small molecule metabolic process GO:0044281 77 0.016
negative regulation of cellular metabolic process GO:0031324 77 0.016
Human
regulation of intracellular signal transduction GO:1902531 57 0.016
protein polymerization GO:0051258 4 0.016
wnt signaling pathway GO:0016055 80 0.016
regulation of cellular protein metabolic process GO:0032268 52 0.016
regulation of nervous system development GO:0051960 90 0.016
cellular protein complex disassembly GO:0043624 1 0.016
muscle structure development GO:0061061 196 0.015
single organism nuclear import GO:1902593 3 0.015
negative regulation of gene expression GO:0010629 65 0.015
Human
regulation of response to stimulus GO:0048583 269 0.015
gland development GO:0048732 143 0.015
amine metabolic process GO:0009308 2 0.015
maternal determination of anterior posterior axis embryo GO:0008358 4 0.015
positive regulation of chromosome organization GO:2001252 1 0.015
membrane invagination GO:0010324 1 0.015
dna metabolic process GO:0006259 27 0.015
photoreceptor cell differentiation GO:0046530 55 0.015
tube morphogenesis GO:0035239 349 0.015
response to wounding GO:0009611 116 0.015
negative regulation of protein transport GO:0051224 3 0.015
positive regulation of ras gtpase activity GO:0032320 1 0.015
stem cell fate commitment GO:0048865 1 0.014
establishment of endothelial barrier GO:0061028 3 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
single fertilization GO:0007338 3 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
meiotic spindle organization GO:0000212 1 0.014
liver development GO:0001889 96 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
positive regulation of chromosome segregation GO:0051984 1 0.014
sensory organ development GO:0007423 393 0.014
cellular response to hypoxia GO:0071456 1 0.014
nuclear import GO:0051170 3 0.014
protein stabilization GO:0050821 2 0.014
regulation of wnt signaling pathway GO:0030111 53 0.013
cell division GO:0051301 20 0.013
gastrulation GO:0007369 208 0.013
cell projection morphogenesis GO:0048858 244 0.013
vasculature development GO:0001944 278 0.013
negative regulation of chromosome organization GO:2001251 1 0.013
cellular catabolic process GO:0044248 27 0.013
regulation of catalytic activity GO:0050790 55 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
regeneration GO:0031099 91 0.013
establishment of organelle localization GO:0051656 45 0.013
protein depolymerization GO:0051261 1 0.013
oocyte anterior posterior axis specification GO:0007314 4 0.013
translational initiation GO:0006413 3 0.013
negative regulation of metabolic process GO:0009892 86 0.013
Human
regulation of cellular protein catabolic process GO:1903362 1 0.012
catabolic process GO:0009056 32 0.012
regulation of cell activation GO:0050865 1 0.012
proepicardium development GO:0003342 4 0.012
regulation of transcription involved in cell fate commitment GO:0060850 1 0.012
positive regulation of muscle organ development GO:0048636 1 0.012
localization of cell GO:0051674 244 0.012
regulation of programmed cell death GO:0043067 101 0.012
double strand break repair GO:0006302 3 0.012
blood vessel development GO:0001568 246 0.012
retina morphogenesis in camera type eye GO:0060042 79 0.012
cellular response to decreased oxygen levels GO:0036294 1 0.012
microtubule polymerization or depolymerization GO:0031109 3 0.012
cellular response to oxygen levels GO:0071453 1 0.012
positive regulation of translation GO:0045727 1 0.011
positive regulation of immune effector process GO:0002699 3 0.011
neuronal stem cell maintenance GO:0097150 2 0.011
mitochondrion organization GO:0007005 4 0.011
rna 3 end processing GO:0031123 2 0.011
cell substrate adhesion GO:0031589 4 0.011
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
Human
mesenchyme development GO:0060485 127 0.011
head development GO:0060322 303 0.011
programmed cell death GO:0012501 119 0.011
macromolecule catabolic process GO:0009057 15 0.011
organic substance catabolic process GO:1901575 28 0.011
neuroblast fate commitment GO:0014017 1 0.011
reciprocal meiotic recombination GO:0007131 1 0.011
response to uv GO:0009411 3 0.011
actin cytoskeleton organization GO:0030036 63 0.011
regulation of mrna processing GO:0050684 3 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
neuroblast fate determination GO:0007400 1 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
septum transversum development GO:0003343 4 0.011
positive regulation of oocyte development GO:0060282 1 0.011
protein localization to nucleus GO:0034504 3 0.010
specification of symmetry GO:0009799 204 0.010
tube closure GO:0060606 1 0.010
negative regulation of cell differentiation GO:0045596 46 0.010
response to monosaccharide GO:0034284 3 0.010
b cell activation GO:0042113 2 0.010
negative regulation of mitotic cell cycle GO:0045930 11 0.010
rna biosynthetic process GO:0032774 181 0.010
Human
negative regulation of cytoplasmic transport GO:1903650 2 0.010
superoxide metabolic process GO:0006801 2 0.010
positive regulation of mrna processing GO:0050685 1 0.010

depdc1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.028
disease of cellular proliferation DOID:14566 0 0.028
organ system cancer DOID:0050686 0 0.028
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
immune system disease DOID:2914 0 0.012
hematopoietic system disease DOID:74 0 0.012