Danio rerio

20 known processes

accn4a

amiloride-sensitive cation channel 4 a

(Aliases: zASIC4.1)

accn4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.085
signal transduction GO:0007165 455 0.074
aging GO:0007568 2 0.068
positive regulation of transport GO:0051050 2 0.046
regulation of metabolic process GO:0019222 359 0.043
response to external stimulus GO:0009605 264 0.039
response to stress GO:0006950 263 0.038
nitrogen compound metabolic process GO:0006807 319 0.037
regulation of biological quality GO:0065008 263 0.036
maintenance of location GO:0051235 4 0.035
stem cell maintenance GO:0019827 4 0.034
response to chemical GO:0042221 320 0.033
establishment of localization GO:0051234 244 0.033
cell surface receptor signaling pathway GO:0007166 325 0.032
positive regulation of catabolic process GO:0009896 4 0.031
system process GO:0003008 185 0.031
cell migration GO:0016477 237 0.031
positive regulation of cell cycle GO:0045787 3 0.031
cellular macromolecule metabolic process GO:0044260 391 0.030
adult behavior GO:0030534 2 0.030
cellular nitrogen compound metabolic process GO:0034641 290 0.029
neurotransmitter transport GO:0006836 2 0.029
single organism metabolic process GO:0044710 217 0.029
head development GO:0060322 303 0.029
chordate embryonic development GO:0043009 271 0.028
regulation of synapse organization GO:0050807 3 0.028
sensory perception of chemical stimulus GO:0007606 3 0.027
cellular component movement GO:0006928 335 0.027
regulation of synapse assembly GO:0051963 3 0.027
cellular response to external stimulus GO:0071496 2 0.027
transport GO:0006810 220 0.027
organonitrogen compound metabolic process GO:1901564 74 0.026
single fertilization GO:0007338 3 0.026
mitochondrion organization GO:0007005 4 0.026
regulation of multicellular organism growth GO:0040014 4 0.026
positive regulation of cellular component biogenesis GO:0044089 3 0.026
determination of bilateral symmetry GO:0009855 204 0.026
ubiquitin dependent protein catabolic process GO:0006511 3 0.026
negative regulation of protein kinase activity GO:0006469 4 0.025
regulation of cytokine production GO:0001817 3 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.025
lipid catabolic process GO:0016042 4 0.025
organic cyclic compound metabolic process GO:1901360 301 0.025
negative regulation of kinase activity GO:0033673 4 0.025
morphogenesis of an epithelium GO:0002009 333 0.025
cellular response to molecule of bacterial origin GO:0071219 3 0.025
heterocycle metabolic process GO:0046483 290 0.025
regulation of inflammatory response GO:0050727 2 0.024
neurotransmitter secretion GO:0007269 2 0.024
digestive tract development GO:0048565 265 0.024
stem cell proliferation GO:0072089 4 0.024
negative regulation of biological process GO:0048519 304 0.024
cell motility GO:0048870 244 0.024
multicellular organism growth GO:0035264 4 0.023
positive regulation of cell activation GO:0050867 1 0.023
tube morphogenesis GO:0035239 349 0.023
single organism transport GO:0044765 206 0.023
small molecule metabolic process GO:0044281 77 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
cognition GO:0050890 1 0.023
regulation of response to stimulus GO:0048583 269 0.022
positive regulation of biological process GO:0048518 253 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
cytokinesis GO:0000910 3 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
regulation of metal ion transport GO:0010959 4 0.022
amine metabolic process GO:0009308 2 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
localization of cell GO:0051674 244 0.022
cellular response to lipopolysaccharide GO:0071222 3 0.022
cell projection morphogenesis GO:0048858 244 0.022
eye development GO:0001654 277 0.022
muscle structure development GO:0061061 196 0.022
regulation of reproductive process GO:2000241 4 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
gastrulation GO:0007369 208 0.021
sensory organ development GO:0007423 393 0.021
phagocytosis GO:0006909 3 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.021
cell morphogenesis GO:0000902 289 0.021
central nervous system development GO:0007417 387 0.021
generation of neurons GO:0048699 385 0.021
proteasomal protein catabolic process GO:0010498 2 0.021
homeostatic process GO:0042592 142 0.021
response to carbohydrate GO:0009743 3 0.021
nuclear transport GO:0051169 4 0.021
regulation of cell activation GO:0050865 1 0.021
gtp metabolic process GO:0046039 4 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
digestive system development GO:0055123 289 0.020
regionalization GO:0003002 274 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
locomotion GO:0040011 313 0.020
lipid storage GO:0019915 1 0.020
cellular ketone metabolic process GO:0042180 11 0.020
neuron development GO:0048666 262 0.020
cellular amine metabolic process GO:0044106 2 0.020
hormone transport GO:0009914 2 0.020
gene expression GO:0010467 252 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
regulation of blood vessel size GO:0050880 2 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.020
translational initiation GO:0006413 3 0.020
endocrine process GO:0050886 2 0.020
response to drug GO:0042493 3 0.020
leukocyte proliferation GO:0070661 1 0.020
meiotic cell cycle process GO:1903046 3 0.020
modification dependent protein catabolic process GO:0019941 3 0.020
gtp catabolic process GO:0006184 2 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
cellular component morphogenesis GO:0032989 336 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
regulation of primary metabolic process GO:0080090 311 0.019
growth GO:0040007 174 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
nucleobase containing compound metabolic process GO:0006139 274 0.019
immune system process GO:0002376 241 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
g protein coupled receptor signaling pathway GO:0007186 74 0.019
cellular response to nutrient levels GO:0031669 2 0.019
regulation of tube size GO:0035150 2 0.019
response to organic substance GO:0010033 153 0.019
cellular amide metabolic process GO:0043603 4 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
organic acid metabolic process GO:0006082 31 0.019
autophagy GO:0006914 4 0.019
carboxylic acid catabolic process GO:0046395 3 0.018
organic cyclic compound biosynthetic process GO:1901362 223 0.018
hormone secretion GO:0046879 2 0.018
cellular protein catabolic process GO:0044257 4 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
tissue remodeling GO:0048771 4 0.018
positive regulation of secretion by cell GO:1903532 1 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
female sex differentiation GO:0046660 4 0.018
embryonic organ development GO:0048568 381 0.018
somite development GO:0061053 96 0.018
oxoacid metabolic process GO:0043436 31 0.018
transmembrane transport GO:0055085 120 0.018
amino acid transport GO:0006865 2 0.018
fertilization GO:0009566 3 0.018
response to wounding GO:0009611 116 0.018
brain development GO:0007420 293 0.018
chemosensory behavior GO:0007635 1 0.018
regulation of synaptic plasticity GO:0048167 1 0.017
mononuclear cell proliferation GO:0032943 1 0.017
regulation of cellular metabolic process GO:0031323 320 0.017
neuron differentiation GO:0030182 353 0.017
negative regulation of cellular process GO:0048523 283 0.017
glucose import GO:0046323 2 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
specification of symmetry GO:0009799 204 0.017
ion transport GO:0006811 114 0.017
response to hexose GO:0009746 3 0.017
protein metabolic process GO:0019538 183 0.017
sequestering of metal ion GO:0051238 3 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.017
sequestering of calcium ion GO:0051208 3 0.017
regulation of protein complex assembly GO:0043254 3 0.017
biosynthetic process GO:0009058 294 0.017
membrane fusion GO:0061025 2 0.017
protein localization to nucleus GO:0034504 3 0.017
cellular response to starvation GO:0009267 1 0.017
single organism localization GO:1902578 225 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
striated muscle cell development GO:0055002 108 0.017
blood vessel development GO:0001568 246 0.017
heart development GO:0007507 313 0.017
cell part morphogenesis GO:0032990 246 0.017
regulation of hormone secretion GO:0046883 2 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
nuclear import GO:0051170 3 0.016
regulation of cell communication GO:0010646 232 0.016
anterior posterior pattern specification GO:0009952 152 0.016
apoptotic process GO:0006915 116 0.016
cellular response to biotic stimulus GO:0071216 3 0.016
positive regulation of chromatin modification GO:1903310 1 0.016
organelle fusion GO:0048284 3 0.016
peptide metabolic process GO:0006518 1 0.016
organic substance biosynthetic process GO:1901576 289 0.016
response to monosaccharide GO:0034284 3 0.016
regulation of cell shape GO:0008360 1 0.016
adherens junction organization GO:0034332 4 0.016
protein targeting to nucleus GO:0044744 3 0.016
female gonad development GO:0008585 4 0.016
response to biotic stimulus GO:0009607 97 0.016
compound eye development GO:0048749 2 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
positive regulation of secretion GO:0051047 1 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
regulation of signaling GO:0023051 235 0.016
regulation of protein catabolic process GO:0042176 1 0.016
multi organism process GO:0051704 134 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
internal peptidyl lysine acetylation GO:0018393 2 0.016
protein localization to plasma membrane GO:0072659 1 0.015
response to other organism GO:0051707 97 0.015
regulation of neurotransmitter secretion GO:0046928 1 0.015
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.015
digestive tract morphogenesis GO:0048546 231 0.015
hemopoiesis GO:0030097 183 0.015
atp catabolic process GO:0006200 4 0.015
regulation of binding GO:0051098 3 0.015
peptide transport GO:0015833 1 0.015
meiotic nuclear division GO:0007126 4 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
cytoplasm organization GO:0007028 4 0.015
response to external biotic stimulus GO:0043207 97 0.015
exocytosis GO:0006887 1 0.015
organelle assembly GO:0070925 110 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
death GO:0016265 121 0.015
protein import GO:0017038 3 0.015
antimicrobial humoral response GO:0019730 2 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
determination of left right symmetry GO:0007368 179 0.015
cell migration involved in gastrulation GO:0042074 79 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
regulation of biosynthetic process GO:0009889 250 0.015
neuroblast proliferation GO:0007405 2 0.015
rna metabolic process GO:0016070 219 0.015
neuron projection development GO:0031175 180 0.015
single organism nuclear import GO:1902593 3 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
organic acid catabolic process GO:0016054 3 0.014
rna localization GO:0006403 4 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
inositol lipid mediated signaling GO:0048017 2 0.014
nucleic acid templated transcription GO:0097659 181 0.014
negative regulation of cytokine production GO:0001818 1 0.014
stem cell division GO:0017145 1 0.014
cellular biosynthetic process GO:0044249 286 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
cellular component biogenesis GO:0044085 178 0.014
positive regulation of cellular process GO:0048522 201 0.014
response to glucose GO:0009749 3 0.014
cellular component assembly GO:0022607 170 0.014
cell death GO:0008219 121 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.014
germ line stem cell maintenance GO:0030718 2 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
regulation of signal transduction GO:0009966 225 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
small molecule catabolic process GO:0044282 3 0.014
negative regulation of defense response GO:0031348 2 0.014
protein secretion GO:0009306 1 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
striated muscle cell differentiation GO:0051146 129 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
regulation of protein transport GO:0051223 3 0.014
developmental growth GO:0048589 166 0.014
regulation of blood pressure GO:0008217 1 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
nucleic acid metabolic process GO:0090304 244 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
actin filament based movement GO:0030048 1 0.014
glucose homeostasis GO:0042593 1 0.014
regulation of developmental process GO:0050793 247 0.014
somitogenesis GO:0001756 87 0.014
regulation of dendrite development GO:0050773 3 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
negative regulation of secretion GO:0051048 2 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
golgi vesicle transport GO:0048193 3 0.014
protein homooligomerization GO:0051260 3 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
secondary metabolic process GO:0019748 3 0.013
carbohydrate homeostasis GO:0033500 1 0.013
regulation of gene expression GO:0010468 265 0.013
camera type eye development GO:0043010 222 0.013
ion transmembrane transport GO:0034220 91 0.013
protein acetylation GO:0006473 2 0.013
regulation of endocrine process GO:0044060 2 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
synaptic vesicle localization GO:0097479 1 0.013
fatty acid catabolic process GO:0009062 1 0.013
maternal determination of anterior posterior axis embryo GO:0008358 4 0.013
protein stabilization GO:0050821 2 0.013
regulation of autophagy GO:0010506 3 0.013
interspecies interaction between organisms GO:0044419 4 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
positive regulation of blood circulation GO:1903524 2 0.013
neuron projection morphogenesis GO:0048812 161 0.013
cellular component disassembly GO:0022411 1 0.013
programmed cell death GO:0012501 119 0.013
muscle cell development GO:0055001 115 0.013
wound healing GO:0042060 90 0.013
membrane invagination GO:0010324 1 0.013
positive regulation of chromosome organization GO:2001252 1 0.013
phototransduction GO:0007602 2 0.013
ameboidal type cell migration GO:0001667 143 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
protein import into nucleus GO:0006606 3 0.013
regulation of localization GO:0032879 104 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
cellular response to organic substance GO:0071310 105 0.013
eye morphogenesis GO:0048592 144 0.013
transcription dna templated GO:0006351 181 0.013
regulation of stem cell proliferation GO:0072091 2 0.012
striated muscle tissue development GO:0014706 110 0.012
response to abiotic stimulus GO:0009628 122 0.012
cell projection organization GO:0030030 284 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
phagocytosis engulfment GO:0006911 1 0.012
mesenchyme development GO:0060485 127 0.012
retina development in camera type eye GO:0060041 146 0.012
muscle cell differentiation GO:0042692 139 0.012
regulation of translational initiation GO:0006446 1 0.012
gland development GO:0048732 143 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
negative regulation of sequestering of calcium ion GO:0051283 4 0.012
regulation of transporter activity GO:0032409 2 0.012
regulation of response to nutrient levels GO:0032107 1 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
neuron neuron synaptic transmission GO:0007270 1 0.012
sensory organ morphogenesis GO:0090596 200 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
regulation of neurotransmitter transport GO:0051588 1 0.012
negative regulation of metabolic process GO:0009892 86 0.012
blood vessel morphogenesis GO:0048514 216 0.012
single organism organelle organization GO:1902589 199 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
negative regulation of catabolic process GO:0009895 3 0.012
positive regulation of histone modification GO:0031058 1 0.012
lymphocyte proliferation GO:0046651 1 0.012
rna biosynthetic process GO:0032774 181 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
chemotaxis GO:0006935 104 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
regulation of wound healing GO:0061041 2 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
vasculature development GO:0001944 278 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
protein polymerization GO:0051258 4 0.012
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.012
protein complex disassembly GO:0043241 1 0.012
ear development GO:0043583 127 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
sensory perception of pain GO:0019233 1 0.011
macromolecular complex disassembly GO:0032984 1 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
positive regulation of cytokine production GO:0001819 2 0.011
regulation of cell projection assembly GO:0060491 4 0.011
developmental programmed cell death GO:0010623 4 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
regulation of calcium ion transport GO:0051924 2 0.011
axonogenesis GO:0007409 152 0.011
multicellular organismal response to stress GO:0033555 2 0.011
positive regulation of cell division GO:0051781 2 0.011
transcription from rna polymerase ii promoter GO:0006366 80 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
ovulation cycle GO:0042698 2 0.011
calcium ion transport into cytosol GO:0060402 3 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.011
regulation of apoptotic process GO:0042981 98 0.011
somatic stem cell maintenance GO:0035019 1 0.011
cellular response to oxygen levels GO:0071453 1 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
segmentation GO:0035282 97 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
protein heterooligomerization GO:0051291 1 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
organelle organization GO:0006996 227 0.011
defense response GO:0006952 47 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
cellular modified amino acid metabolic process GO:0006575 3 0.011
negative regulation of nuclear division GO:0051784 3 0.011
intracellular signal transduction GO:0035556 85 0.011
positive regulation of immune effector process GO:0002699 3 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
regeneration GO:0031099 91 0.011
somatic muscle development GO:0007525 4 0.011
lateral inhibition GO:0046331 1 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
endocrine hormone secretion GO:0060986 2 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
intracellular mrna localization GO:0008298 1 0.011
positive regulation of reproductive process GO:2000243 2 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
circulatory system process GO:0003013 87 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
cellular response to radiation GO:0071478 4 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
heart morphogenesis GO:0003007 156 0.011
response to bacterium GO:0009617 58 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
taxis GO:0042330 109 0.010
ovulation cycle process GO:0022602 2 0.010
regulation of cell differentiation GO:0045595 142 0.010
response to corticosteroid GO:0031960 1 0.010
positive regulation of protein complex assembly GO:0031334 2 0.010
embryonic heart tube development GO:0035050 133 0.010
release of sequestered calcium ion into cytosol GO:0051209 3 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
regulation of transcription dna templated GO:0006355 213 0.010
regulation of dendrite morphogenesis GO:0048814 3 0.010
regulation of rna biosynthetic process GO:2001141 213 0.010
regulation of dna replication GO:0006275 3 0.010
melanin metabolic process GO:0006582 2 0.010
regulation of circadian rhythm GO:0042752 4 0.010
phosphatidylinositol mediated signaling GO:0048015 2 0.010
determination of heart left right asymmetry GO:0061371 117 0.010
spermatid differentiation GO:0048515 2 0.010
synaptic vesicle transport GO:0048489 1 0.010
cytosolic calcium ion transport GO:0060401 3 0.010
regulation of sequestering of calcium ion GO:0051282 4 0.010
regulation of protein targeting GO:1903533 2 0.010
cell substrate adhesion GO:0031589 4 0.010
regulation of mrna processing GO:0050684 3 0.010
regulation of macromolecule biosynthetic process GO:0010556 225 0.010
negative regulation of multi organism process GO:0043901 3 0.010
regulation of programmed cell death GO:0043067 101 0.010
regulation of muscle contraction GO:0006937 3 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010

accn4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
musculoskeletal system disease DOID:17 0 0.021
disease of metabolism DOID:0014667 0 0.018
nervous system disease DOID:863 0 0.017
muscular disease DOID:0080000 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
muscle tissue disease DOID:66 0 0.011
organ system cancer DOID:0050686 0 0.010