Danio rerio

0 known processes

lhx8a

LIM homeobox 8a

(Aliases: lhx8,cb875,fk78g12,wu:fk78g12,lhx7)

lhx8a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization GO:0051234 244 0.517
cell morphogenesis involved in differentiation GO:0000904 195 0.511
Zebrafish
response to stress GO:0006950 263 0.459
cell projection morphogenesis GO:0048858 244 0.424
Zebrafish
response to chemical GO:0042221 320 0.409
Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.394
Zebrafish
response to external stimulus GO:0009605 264 0.358
Zebrafish
g protein coupled receptor signaling pathway GO:0007186 74 0.321
chemotaxis GO:0006935 104 0.309
Zebrafish
regulation of signal transduction GO:0009966 225 0.304
single organism transport GO:0044765 206 0.301
larval development GO:0002164 2 0.289
cell morphogenesis GO:0000902 289 0.280
Zebrafish
transport GO:0006810 220 0.269
cellular component morphogenesis GO:0032989 336 0.253
Zebrafish
locomotion GO:0040011 313 0.222
Zebrafish
central nervous system development GO:0007417 387 0.213
Zebrafish Mouse
signal transduction GO:0007165 455 0.211
generation of neurons GO:0048699 385 0.197
Zebrafish Mouse
neuron projection morphogenesis GO:0048812 161 0.189
Zebrafish
regulation of apoptotic process GO:0042981 98 0.181
regulation of gene expression GO:0010468 265 0.170
Zebrafish Worm Fly
neuron differentiation GO:0030182 353 0.152
Zebrafish Mouse
response to ketone GO:1901654 1 0.148
regulation of response to stimulus GO:0048583 269 0.148
regulation of cell death GO:0010941 103 0.147
mechanoreceptor differentiation GO:0042490 37 0.143
Zebrafish
camera type eye development GO:0043010 222 0.139
Zebrafish
homeostatic process GO:0042592 142 0.138
regulation of signaling GO:0023051 235 0.137
tube morphogenesis GO:0035239 349 0.133
Zebrafish
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.131
Zebrafish
biosynthetic process GO:0009058 294 0.130
Worm
cognition GO:0050890 1 0.129
Mouse
positive regulation of biological process GO:0048518 253 0.126
axonogenesis GO:0007409 152 0.119
Zebrafish
heterocycle metabolic process GO:0046483 290 0.118
Worm
regulation of nitrogen compound metabolic process GO:0051171 251 0.111
Worm
embryonic cranial skeleton morphogenesis GO:0048701 90 0.111
regulation of macromolecule metabolic process GO:0060255 317 0.110
Zebrafish Worm Fly
organelle organization GO:0006996 227 0.107
sensory organ development GO:0007423 393 0.107
Zebrafish Fly
regulation of metabolic process GO:0019222 359 0.106
Zebrafish Worm Fly
system process GO:0003008 185 0.106
Zebrafish Mouse
cellular component movement GO:0006928 335 0.105
Zebrafish
aging GO:0007568 2 0.100
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.099
Worm
positive regulation of cell cycle GO:0045787 3 0.099
epithelial cell differentiation GO:0030855 116 0.098
Zebrafish
single organism organelle organization GO:1902589 199 0.097
localization of cell GO:0051674 244 0.096
single organism localization GO:1902578 225 0.094
cell migration GO:0016477 237 0.093
cell surface receptor signaling pathway GO:0007166 325 0.091
digestive tract morphogenesis GO:0048546 231 0.089
muscle tissue development GO:0060537 110 0.086
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.085
Worm
sensory organ morphogenesis GO:0090596 200 0.085
Zebrafish
regulation of cell communication GO:0010646 232 0.084
regulation of programmed cell death GO:0043067 101 0.083
regulation of biosynthetic process GO:0009889 250 0.083
Worm
ameboidal type cell migration GO:0001667 143 0.082
ion transport GO:0006811 114 0.080
eye morphogenesis GO:0048592 144 0.080
Zebrafish
digestive tract development GO:0048565 265 0.080
single organism metabolic process GO:0044710 217 0.078
transcription from rna polymerase ii promoter GO:0006366 80 0.076
positive regulation of transport GO:0051050 2 0.076
forebrain generation of neurons GO:0021872 14 0.074
Mouse
type b pancreatic cell development GO:0003323 4 0.073
Zebrafish
brain development GO:0007420 293 0.072
Zebrafish Mouse
regulation of biological quality GO:0065008 263 0.072
taxis GO:0042330 109 0.071
Zebrafish
nucleobase containing compound biosynthetic process GO:0034654 205 0.071
Worm
heart development GO:0007507 313 0.070
Zebrafish
gastrulation GO:0007369 208 0.068
behavior GO:0007610 74 0.067
Zebrafish Mouse
chemosensory behavior GO:0007635 1 0.065
cell fate commitment GO:0045165 99 0.063
Zebrafish Worm
organic substance biosynthetic process GO:1901576 289 0.059
Worm
cell death GO:0008219 121 0.058
regulation of blood circulation GO:1903522 32 0.058
Zebrafish
cellular component assembly GO:0022607 170 0.058
eye development GO:0001654 277 0.058
Zebrafish Fly
cytoskeleton organization GO:0007010 96 0.057
cellular nitrogen compound biosynthetic process GO:0044271 218 0.057
Worm
dopamine metabolic process GO:0042417 2 0.057
regulation of localization GO:0032879 104 0.055
cell motility GO:0048870 244 0.055
actin filament based process GO:0030029 64 0.054
chordate embryonic development GO:0043009 271 0.054
Zebrafish
heart contraction GO:0060047 71 0.054
Zebrafish
regulation of multicellular organism growth GO:0040014 4 0.054
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.053
regulation of heart contraction GO:0008016 32 0.053
Zebrafish
maintenance of location GO:0051235 4 0.053
transcription dna templated GO:0006351 181 0.053
Worm
stem cell proliferation GO:0072089 4 0.053
morphogenesis of an epithelial sheet GO:0002011 49 0.052
Zebrafish
adult behavior GO:0030534 2 0.052
stem cell maintenance GO:0019827 4 0.052
neuron projection extension GO:1990138 45 0.051
Zebrafish
positive regulation of cellular metabolic process GO:0031325 94 0.051
fin development GO:0033333 77 0.050
mitochondrion organization GO:0007005 4 0.049
regulation of cellular biosynthetic process GO:0031326 245 0.049
Worm
circulatory system process GO:0003013 87 0.048
Zebrafish
neuron projection development GO:0031175 180 0.048
Zebrafish
striated muscle tissue development GO:0014706 110 0.048
Zebrafish
spinal cord motor neuron differentiation GO:0021522 26 0.046
Zebrafish
catechol containing compound biosynthetic process GO:0009713 2 0.046
endoderm formation GO:0001706 29 0.046
death GO:0016265 121 0.046
cellular aromatic compound metabolic process GO:0006725 295 0.046
Worm
gene expression GO:0010467 252 0.044
Zebrafish Worm Fly
neuron projection guidance GO:0097485 86 0.044
Zebrafish
regulation of developmental process GO:0050793 247 0.044
mitotic cell cycle GO:0000278 64 0.044
head development GO:0060322 303 0.043
Zebrafish Mouse
positive regulation of cellular catabolic process GO:0031331 3 0.042
embryo development ending in birth or egg hatching GO:0009792 271 0.042
Zebrafish
olfactory placode morphogenesis GO:0071699 7 0.042
developmental maturation GO:0021700 34 0.042
specification of symmetry GO:0009799 204 0.042
cellular biosynthetic process GO:0044249 286 0.041
Worm
microtubule organizing center organization GO:0031023 1 0.041
positive regulation of catabolic process GO:0009896 4 0.041
negative regulation of biological process GO:0048519 304 0.041
apoptotic process GO:0006915 116 0.040
regulation of anatomical structure morphogenesis GO:0022603 130 0.040
mechanosensory behavior GO:0007638 2 0.040
regulation of nucleic acid templated transcription GO:1903506 213 0.039
Worm
fin morphogenesis GO:0033334 53 0.039
dorsal ventral pattern formation GO:0009953 125 0.039
axon guidance GO:0007411 86 0.038
Zebrafish
spindle assembly GO:0051225 2 0.037
response to organic substance GO:0010033 153 0.037
nucleic acid templated transcription GO:0097659 181 0.037
Worm
intracellular signal transduction GO:0035556 85 0.037
response to abiotic stimulus GO:0009628 122 0.036
Zebrafish
growth GO:0040007 174 0.036
Zebrafish
neuron development GO:0048666 262 0.036
Zebrafish Mouse
determination of ventral identity GO:0048264 21 0.036
response to hormone GO:0009725 48 0.034
negative regulation of programmed cell death GO:0043069 58 0.033
regulation of reproductive process GO:2000241 4 0.033
positive regulation of cellular process GO:0048522 201 0.032
regulation of primary metabolic process GO:0080090 311 0.032
Worm
regulation of tube size GO:0035150 2 0.031
regulation of establishment of protein localization GO:0070201 4 0.031
embryonic organ morphogenesis GO:0048562 274 0.031
Zebrafish
regulation of rna biosynthetic process GO:2001141 213 0.031
Worm
regulation of oocyte development GO:0060281 3 0.031
apoptotic signaling pathway GO:0097190 23 0.031
chemical homeostasis GO:0048878 49 0.031
regulation of embryonic development GO:0045995 47 0.030
regulation of catalytic activity GO:0050790 55 0.030
cellular macromolecule biosynthetic process GO:0034645 224 0.030
Worm
determination of dorsal ventral asymmetry GO:0048262 34 0.030
metal ion homeostasis GO:0055065 26 0.030
microtubule based process GO:0007017 60 0.030
cell fate specification GO:0001708 68 0.030
Zebrafish Worm
catechol containing compound metabolic process GO:0009712 2 0.030
nucleobase containing compound metabolic process GO:0006139 274 0.029
Worm
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 7 0.028
response to amphetamine GO:0001975 1 0.028
positive regulation of cellular biosynthetic process GO:0031328 68 0.028
indole containing compound metabolic process GO:0042430 2 0.028
regulation of autophagy GO:0010506 3 0.027
circadian sleep wake cycle process GO:0022410 2 0.027
regulation of multicellular organismal process GO:0051239 277 0.027
Zebrafish
nerve development GO:0021675 45 0.027
Zebrafish
autophagy GO:0006914 4 0.027
oocyte maturation GO:0001556 4 0.026
centrosome organization GO:0051297 1 0.026
vasculature development GO:0001944 278 0.026
nitrogen compound metabolic process GO:0006807 319 0.025
Worm
regulation of molecular function GO:0065009 70 0.025
phagocytosis GO:0006909 3 0.025
cell projection organization GO:0030030 284 0.025
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.025
Worm
hindbrain development GO:0030902 91 0.025
Zebrafish
regulation of circadian rhythm GO:0042752 4 0.025
positive regulation of gene expression GO:0010628 71 0.025
cell part morphogenesis GO:0032990 246 0.025
Zebrafish
endodermal cell fate determination GO:0007493 2 0.025
actin cytoskeleton organization GO:0030036 63 0.025
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.024
protein localization GO:0008104 40 0.024
inner ear morphogenesis GO:0042472 63 0.024
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.024
Worm
hepaticobiliary system development GO:0061008 98 0.024
endodermal cell fate specification GO:0001714 17 0.024
regulation of mrna processing GO:0050684 3 0.024
negative regulation of nucleotide metabolic process GO:0045980 7 0.023
cellular localization GO:0051641 97 0.023
cell maturation GO:0048469 23 0.023
convergent extension GO:0060026 118 0.023
phosphate containing compound metabolic process GO:0006796 108 0.022
programmed cell death GO:0012501 119 0.022
positive regulation of cell division GO:0051781 2 0.022
negative regulation of apoptotic process GO:0043066 55 0.022
regulation of cellular component organization GO:0051128 86 0.022
monovalent inorganic cation homeostasis GO:0055067 9 0.022
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.022
muscle structure development GO:0061061 196 0.022
Zebrafish
regulation of intracellular protein transport GO:0033157 3 0.022
positive regulation of transcription dna templated GO:0045893 57 0.022
protein metabolic process GO:0019538 183 0.021
camera type eye morphogenesis GO:0048593 108 0.021
Zebrafish
regulation of ion transmembrane transporter activity GO:0032412 2 0.021
determination of bilateral symmetry GO:0009855 204 0.020
digestive system development GO:0055123 289 0.020
Zebrafish
retinal ganglion cell axon guidance GO:0031290 35 0.020
Zebrafish
negative regulation of cyclic nucleotide metabolic process GO:0030800 7 0.020
urogenital system development GO:0001655 97 0.020
Zebrafish
regulation of organ morphogenesis GO:2000027 35 0.020
protein localization to nucleus GO:0034504 3 0.020
formation of primary germ layer GO:0001704 62 0.020
catecholamine metabolic process GO:0006584 2 0.020
multicellular organism growth GO:0035264 4 0.020
macromolecular complex subunit organization GO:0043933 74 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
multicellular organismal response to stress GO:0033555 2 0.019
bmp signaling pathway involved in heart jogging GO:0003303 14 0.019
blood vessel development GO:0001568 246 0.019
cellular component biogenesis GO:0044085 178 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.019
Worm
epiboly GO:0090504 41 0.019
appendage development GO:0048736 80 0.019
tissue remodeling GO:0048771 4 0.019
embryonic organ development GO:0048568 381 0.019
Zebrafish
axon extension GO:0048675 45 0.019
Zebrafish
organic substance transport GO:0071702 58 0.019
positive regulation of secretion GO:0051047 1 0.019
regulation of transmembrane transporter activity GO:0022898 2 0.018
muscle cell differentiation GO:0042692 139 0.018
Zebrafish
inner ear receptor cell differentiation GO:0060113 29 0.018
Zebrafish
developmental growth GO:0048589 166 0.018
Zebrafish
organelle assembly GO:0070925 110 0.018
regulation of transcription dna templated GO:0006355 213 0.018
Worm
negative regulation of cellular metabolic process GO:0031324 77 0.017
epithelial cell development GO:0002064 42 0.017
Zebrafish
response to osmotic stress GO:0006970 11 0.017
macromolecule biosynthetic process GO:0009059 227 0.017
Worm
response to wounding GO:0009611 116 0.017
cellular macromolecule metabolic process GO:0044260 391 0.017
Worm
negative regulation of cell death GO:0060548 60 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.016
negative regulation of cellular biosynthetic process GO:0031327 55 0.016
central nervous system neuron differentiation GO:0021953 74 0.016
Zebrafish Mouse
positive regulation of cell communication GO:0010647 56 0.016
establishment of localization in cell GO:0051649 77 0.016
nuclear envelope organization GO:0006998 2 0.016
skeletal system morphogenesis GO:0048705 102 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
inner ear development GO:0048839 126 0.016
Zebrafish
protein complex biogenesis GO:0070271 30 0.016
neuroblast proliferation GO:0007405 2 0.016
regulation of phosphate metabolic process GO:0019220 43 0.015
sodium ion homeostasis GO:0055078 3 0.015
determination of left right symmetry GO:0007368 179 0.015
negative regulation of metabolic process GO:0009892 86 0.015
negative regulation of cellular process GO:0048523 283 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.015
rna biosynthetic process GO:0032774 181 0.015
Worm
closure of optic fissure GO:0061386 6 0.015
Zebrafish
regulation of blood vessel size GO:0050880 2 0.015
negative regulation of reproductive process GO:2000242 3 0.015
transmission of nerve impulse GO:0019226 19 0.015
negative regulation of signaling GO:0023057 96 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.015
endodermal cell differentiation GO:0035987 19 0.015
ventral spinal cord development GO:0021517 35 0.015
Zebrafish
locomotory behavior GO:0007626 34 0.015
smad protein complex assembly GO:0007183 1 0.015
cellular response to light stimulus GO:0071482 4 0.014
regulation of camp biosynthetic process GO:0030817 9 0.014
negative regulation of biosynthetic process GO:0009890 55 0.014
liver development GO:0001889 96 0.014
regulation of cell cycle GO:0051726 52 0.014
cellular nitrogen compound metabolic process GO:0034641 290 0.014
Worm
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
cellular protein catabolic process GO:0044257 4 0.014
regionalization GO:0003002 274 0.014
Zebrafish
mesoderm development GO:0007498 88 0.014
diencephalon development GO:0021536 58 0.014
Zebrafish
single organism cellular localization GO:1902580 46 0.014
neurological system process GO:0050877 62 0.014
Mouse
aromatic amino acid family metabolic process GO:0009072 1 0.014
regulation of transcription involved in cell fate commitment GO:0060850 1 0.013
anatomical structure homeostasis GO:0060249 36 0.013
phosphorus metabolic process GO:0006793 109 0.013
skeletal system development GO:0001501 181 0.013
post anal tail morphogenesis GO:0036342 19 0.013
appendage morphogenesis GO:0035107 56 0.013
retina morphogenesis in camera type eye GO:0060042 79 0.013
female meiotic division GO:0007143 2 0.013
wound healing GO:0042060 90 0.013
response to endogenous stimulus GO:0009719 83 0.013
cellular response to external stimulus GO:0071496 2 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
meiotic cell cycle process GO:1903046 3 0.013
angiogenesis GO:0001525 158 0.013
regulation of rna metabolic process GO:0051252 224 0.013
Worm
regulation of cytoplasmic transport GO:1903649 4 0.013
stem cell development GO:0048864 82 0.013
organonitrogen compound biosynthetic process GO:1901566 47 0.013
carbohydrate derivative metabolic process GO:1901135 61 0.012
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.012
muscle cell development GO:0055001 115 0.012
epidermal cell differentiation GO:0009913 36 0.012
Zebrafish
cell migration involved in gastrulation GO:0042074 79 0.012
protein import GO:0017038 3 0.012
astrocyte differentiation GO:0048708 1 0.012
developmental growth involved in morphogenesis GO:0060560 86 0.012
Zebrafish
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
pectoral fin development GO:0033339 50 0.012
meiotic cell cycle GO:0051321 5 0.012
cell cycle GO:0007049 93 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
cell proliferation GO:0008283 80 0.012
regulation of protein transport GO:0051223 3 0.012
regulation of metal ion transport GO:0010959 4 0.012
meiotic nuclear division GO:0007126 4 0.012
small molecule metabolic process GO:0044281 77 0.012
positive regulation of biosynthetic process GO:0009891 68 0.012
heart looping GO:0001947 94 0.012
gtp catabolic process GO:0006184 2 0.012
optomotor response GO:0071632 1 0.011
Zebrafish
reproduction GO:0000003 40 0.011
specification of organ identity GO:0010092 2 0.011
negative regulation of cell communication GO:0010648 96 0.011
ion homeostasis GO:0050801 41 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
Worm
cardiac muscle cell differentiation GO:0055007 30 0.011
Zebrafish
regulation of endodermal cell fate specification GO:0042663 15 0.011
gland development GO:0048732 143 0.011
regulation of gene expression epigenetic GO:0040029 11 0.011
negative regulation of gene expression GO:0010629 65 0.011
single organism behavior GO:0044708 24 0.011
Zebrafish Mouse
hemopoiesis GO:0030097 183 0.011
ear development GO:0043583 127 0.011
Zebrafish
regulation of lipase activity GO:0060191 2 0.011
positive regulation of cellular component biogenesis GO:0044089 3 0.011
mesenchyme development GO:0060485 127 0.011
regulation of transporter activity GO:0032409 2 0.011
microtubule cytoskeleton organization GO:0000226 33 0.011
regulation of protein metabolic process GO:0051246 56 0.011
ectodermal placode development GO:0071696 37 0.011
negative regulation of cyclase activity GO:0031280 6 0.010
response to carbohydrate GO:0009743 3 0.010
positive regulation of rna biosynthetic process GO:1902680 57 0.010
kupffer s vesicle development GO:0070121 50 0.010
regulation of system process GO:0044057 40 0.010
Zebrafish
negative regulation of molecular function GO:0044092 23 0.010
nuclear import GO:0051170 3 0.010
multicellular organismal signaling GO:0035637 22 0.010
ear morphogenesis GO:0042471 64 0.010
Zebrafish
cardiac muscle tissue development GO:0048738 48 0.010
Zebrafish
regeneration GO:0031099 91 0.010
establishment or maintenance of cell polarity GO:0007163 29 0.010

lhx8a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.016