Danio rerio

25 known processes

actc1a

actin, alpha, cardiac muscle 1a

(Aliases: actcl,actc1l)

actc1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heart development GO:0007507 313 0.950
cardiac myofibril assembly GO:0055003 9 0.785
muscle cell development GO:0055001 115 0.709
ventricular cardiac myofibril assembly GO:0055005 4 0.607
positive regulation of blood circulation GO:1903524 2 0.606
striated muscle cell differentiation GO:0051146 129 0.601
heart morphogenesis GO:0003007 156 0.573
system process GO:0003008 185 0.501
cellular component assembly involved in morphogenesis GO:0010927 107 0.454
regulation of heart contraction GO:0008016 32 0.420
cilium organization GO:0044782 71 0.415
actin filament based process GO:0030029 64 0.392
atrial cardiac myofibril assembly GO:0055004 2 0.391
regulation of blood circulation GO:1903522 32 0.381
positive regulation of heart contraction GO:0045823 2 0.380
myofibril assembly GO:0030239 48 0.379
striated muscle cell development GO:0055002 108 0.370
organelle assembly GO:0070925 110 0.338
cardiac muscle contraction GO:0060048 6 0.322
ventricular cardiac muscle cell development GO:0055015 5 0.311
heart process GO:0003015 71 0.303
blood circulation GO:0008015 87 0.298
single organism localization GO:1902578 225 0.294
muscle cell differentiation GO:0042692 139 0.294
cellular component morphogenesis GO:0032989 336 0.280
cellular component biogenesis GO:0044085 178 0.275
circulatory system process GO:0003013 87 0.275
muscle structure development GO:0061061 196 0.269
regulation of system process GO:0044057 40 0.265
sarcomere organization GO:0045214 26 0.265
cardiac muscle cell development GO:0055013 20 0.263
ventricular cardiac muscle tissue development GO:0003229 3 0.262
ventricular cardiac muscle cell differentiation GO:0055012 6 0.256
regulation of tube size GO:0035150 2 0.250
organelle organization GO:0006996 227 0.250
actomyosin structure organization GO:0031032 53 0.246
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.241
embryonic heart tube morphogenesis GO:0003143 108 0.235
cilium morphogenesis GO:0060271 85 0.231
regulation of muscle contraction GO:0006937 3 0.220
neuron development GO:0048666 262 0.215
heart contraction GO:0060047 71 0.205
heart looping GO:0001947 94 0.200
maintenance of location GO:0051235 4 0.187
cardiac muscle tissue development GO:0048738 48 0.186
single organism organelle organization GO:1902589 199 0.185
determination of left right symmetry GO:0007368 179 0.185
striated muscle contraction GO:0006941 12 0.176
cardiac muscle tissue morphogenesis GO:0055008 7 0.168
cardiac muscle cell differentiation GO:0055007 30 0.164
cardiocyte differentiation GO:0035051 44 0.156
embryonic heart tube development GO:0035050 133 0.156
Zebrafish
embryo development ending in birth or egg hatching GO:0009792 271 0.152
brain development GO:0007420 293 0.148
striated muscle tissue development GO:0014706 110 0.147
larval development GO:0002164 2 0.142
regulation of nucleoside metabolic process GO:0009118 2 0.141
single organism transport GO:0044765 206 0.139
specification of symmetry GO:0009799 204 0.135
embryonic organ development GO:0048568 381 0.130
Zebrafish
cardiac chamber development GO:0003205 19 0.129
lipid storage GO:0019915 1 0.127
regulation of blood vessel size GO:0050880 2 0.127
positive regulation of nucleotide catabolic process GO:0030813 1 0.124
calcium ion import GO:0070509 4 0.116
nitrogen compound metabolic process GO:0006807 319 0.116
central nervous system development GO:0007417 387 0.113
regulation of purine nucleotide catabolic process GO:0033121 2 0.111
endocardial cushion morphogenesis GO:0003203 3 0.111
regulation of myotube differentiation GO:0010830 2 0.110
cellular biosynthetic process GO:0044249 286 0.110
actin filament based movement GO:0030048 1 0.110
endocardial cushion formation GO:0003272 2 0.107
cellular component assembly GO:0022607 170 0.105
morphogenesis of an epithelium GO:0002009 333 0.104
determination of bilateral symmetry GO:0009855 204 0.102
heart jogging GO:0003146 40 0.100
actin cytoskeleton organization GO:0030036 63 0.093
cardiac chamber morphogenesis GO:0003206 12 0.092
muscle system process GO:0003012 20 0.090
transport GO:0006810 220 0.089
cardiac cell development GO:0055006 21 0.087
chordate embryonic development GO:0043009 271 0.087
developmental growth GO:0048589 166 0.087
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.084
positive regulation of catabolic process GO:0009896 4 0.083
negative regulation of cellular process GO:0048523 283 0.083
negative regulation of biological process GO:0048519 304 0.083
cellular aromatic compound metabolic process GO:0006725 295 0.082
regulation of cardiac muscle contraction GO:0055117 2 0.078
monovalent inorganic cation transport GO:0015672 42 0.076
tube morphogenesis GO:0035239 349 0.075
heterocycle metabolic process GO:0046483 290 0.071
protein targeting to nucleus GO:0044744 3 0.070
organophosphate metabolic process GO:0019637 37 0.068
regulation of nucleotide catabolic process GO:0030811 2 0.068
inorganic cation transmembrane transport GO:0098662 50 0.068
protein localization to nucleus GO:0034504 3 0.065
regulation of mechanoreceptor differentiation GO:0045631 1 0.064
actin mediated cell contraction GO:0070252 1 0.063
muscle tissue development GO:0060537 110 0.060
cardiac ventricle morphogenesis GO:0003208 7 0.059
somitogenesis GO:0001756 87 0.059
cilium assembly GO:0042384 58 0.058
segmentation GO:0035282 97 0.057
atrial cardiac muscle cell development GO:0055014 4 0.056
regulation of metal ion transport GO:0010959 4 0.056
metal ion transport GO:0030001 58 0.055
nerve development GO:0021675 45 0.055
gtp metabolic process GO:0046039 4 0.054
growth GO:0040007 174 0.054
cytoskeleton organization GO:0007010 96 0.054
nitric oxide biosynthetic process GO:0006809 2 0.053
positive regulation of transport GO:0051050 2 0.053
organonitrogen compound metabolic process GO:1901564 74 0.053
mitotic cell cycle GO:0000278 64 0.052
positive regulation of cellular catabolic process GO:0031331 3 0.052
meiotic nuclear division GO:0007126 4 0.050
regulation of striated muscle contraction GO:0006942 2 0.050
establishment of protein localization to organelle GO:0072594 4 0.049
cytoskeleton dependent cytokinesis GO:0061640 3 0.048
regulation of protein transport GO:0051223 3 0.047
cytokinesis GO:0000910 3 0.047
fertilization GO:0009566 3 0.046
nuclear transport GO:0051169 4 0.045
regulation of cytoplasmic transport GO:1903649 4 0.045
endocardial cushion development GO:0003197 6 0.045
determination of heart left right asymmetry GO:0061371 117 0.045
calcium ion transport into cytosol GO:0060402 3 0.044
cellular component movement GO:0006928 335 0.044
regulation of cellular component organization GO:0051128 86 0.043
regulation of establishment of protein localization GO:0070201 4 0.043
response to wounding GO:0009611 116 0.040
adult behavior GO:0030534 2 0.039
muscle organ morphogenesis GO:0048644 8 0.039
regulation of blood pressure GO:0008217 1 0.039
neurological system process GO:0050877 62 0.039
regulation of cell growth GO:0001558 29 0.038
regulation of ion transmembrane transporter activity GO:0032412 2 0.038
sexual reproduction GO:0019953 36 0.038
embryonic skeletal system development GO:0048706 97 0.037
protein import GO:0017038 3 0.037
axon ensheathment in central nervous system GO:0032291 2 0.037
ras protein signal transduction GO:0007265 7 0.036
phosphorus metabolic process GO:0006793 109 0.036
aging GO:0007568 2 0.035
positive regulation of nucleoside metabolic process GO:0045979 1 0.035
regulation of binding GO:0051098 3 0.035
neuron differentiation GO:0030182 353 0.034
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.033
organic cyclic compound metabolic process GO:1901360 301 0.033
fluid transport GO:0042044 17 0.033
regulation of cell shape GO:0008360 1 0.033
nucleobase containing small molecule metabolic process GO:0055086 32 0.032
small gtpase mediated signal transduction GO:0007264 8 0.032
regulation of developmental process GO:0050793 247 0.032
cation transport GO:0006812 81 0.032
regulation of anatomical structure size GO:0090066 33 0.032
regulation of protein binding GO:0043393 3 0.031
purine ribonucleoside metabolic process GO:0046128 10 0.031
organic acid metabolic process GO:0006082 31 0.031
ion transport GO:0006811 114 0.031
nucleobase containing compound metabolic process GO:0006139 274 0.031
cellular nitrogen compound metabolic process GO:0034641 290 0.031
embryonic cranial skeleton morphogenesis GO:0048701 90 0.030
establishment of localization GO:0051234 244 0.030
mitotic cell cycle process GO:1903047 48 0.030
somatic muscle development GO:0007525 4 0.030
cation transmembrane transport GO:0098655 65 0.029
trabecula morphogenesis GO:0061383 2 0.029
muscle tissue morphogenesis GO:0060415 7 0.029
cranial nerve development GO:0021545 42 0.028
localization of cell GO:0051674 244 0.028
atp catabolic process GO:0006200 4 0.028
sodium ion transmembrane transport GO:0035725 21 0.028
regulation of inflammatory response GO:0050727 2 0.027
mitotic cytokinesis GO:0000281 3 0.027
sensory system development GO:0048880 76 0.027
multicellular organismal signaling GO:0035637 22 0.027
reactive nitrogen species metabolic process GO:2001057 0 0.027
transmission of nerve impulse GO:0019226 19 0.027
regulation of stem cell differentiation GO:2000736 4 0.027
cell cycle GO:0007049 93 0.027
single organism metabolic process GO:0044710 217 0.027
response to steroid hormone GO:0048545 35 0.027
regulation of membrane potential GO:0042391 23 0.026
membrane repolarization GO:0086009 2 0.026
cellular response to hormone stimulus GO:0032870 39 0.026
eye morphogenesis GO:0048592 144 0.026
cellular response to steroid hormone stimulus GO:0071383 31 0.026
cardiac ventricle development GO:0003231 9 0.026
regulation of actin filament based movement GO:1903115 1 0.026
cognition GO:0050890 1 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
generation of neurons GO:0048699 385 0.025
sensory organ development GO:0007423 393 0.025
regulation of nucleocytoplasmic transport GO:0046822 2 0.025
positive regulation of cellular component biogenesis GO:0044089 3 0.025
negative regulation of cellular component organization GO:0051129 16 0.024
wound healing GO:0042060 90 0.024
somite development GO:0061053 96 0.024
cardiac muscle cell contraction GO:0086003 1 0.024
intestinal absorption GO:0050892 2 0.024
muscle contraction GO:0006936 18 0.024
lamellipodium assembly GO:0030032 1 0.024
response to hormone GO:0009725 48 0.023
forebrain regionalization GO:0021871 4 0.023
protein import into nucleus GO:0006606 3 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
regulation of transport GO:0051049 45 0.023
single fertilization GO:0007338 3 0.023
organic substance biosynthetic process GO:1901576 289 0.022
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.022
rna localization GO:0006403 4 0.022
cellular protein metabolic process GO:0044267 129 0.022
cell growth GO:0016049 57 0.022
carbohydrate derivative metabolic process GO:1901135 61 0.022
chemosensory behavior GO:0007635 1 0.022
ion transmembrane transport GO:0034220 91 0.021
lipid digestion GO:0044241 3 0.021
nucleoside metabolic process GO:0009116 11 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
positive regulation of stem cell proliferation GO:2000648 1 0.021
sleep GO:0030431 1 0.021
cellular macromolecule metabolic process GO:0044260 391 0.021
plasma membrane repair GO:0001778 2 0.021
oxoacid metabolic process GO:0043436 31 0.021
skeletal system development GO:0001501 181 0.020
cardiac muscle fiber development GO:0048739 3 0.020
regulation of biological quality GO:0065008 263 0.020
odontogenesis of dentin containing tooth GO:0042475 1 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
response to activity GO:0014823 14 0.020
regulation of response to cytokine stimulus GO:0060759 3 0.020
regulation of anatomical structure morphogenesis GO:0022603 130 0.020
head development GO:0060322 303 0.020
regulation of localization GO:0032879 104 0.020
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.019
eye development GO:0001654 277 0.019
reactive oxygen species metabolic process GO:0072593 6 0.019
regulation of transmembrane transporter activity GO:0022898 2 0.019
regulation of establishment of planar polarity GO:0090175 4 0.019
potassium ion transport GO:0006813 10 0.019
neuron projection morphogenesis GO:0048812 161 0.018
water homeostasis GO:0030104 4 0.018
intracellular mrna localization GO:0008298 1 0.018
trabecula formation GO:0060343 2 0.018
lymphoid lineage cell migration GO:0097534 4 0.018
atrial cardiac muscle cell differentiation GO:0055011 5 0.017
organic substance transport GO:0071702 58 0.017
regulation of synapse assembly GO:0051963 3 0.017
smooth muscle contraction GO:0006939 2 0.017
positive regulation of biological process GO:0048518 253 0.017
venous blood vessel morphogenesis GO:0048845 3 0.017
apoptotic process GO:0006915 116 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
oogenesis GO:0048477 14 0.017
embryonic viscerocranium morphogenesis GO:0048703 52 0.017
response to stress GO:0006950 263 0.017
cell morphogenesis GO:0000902 289 0.017
single organism nuclear import GO:1902593 3 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
cytosolic calcium ion transport GO:0060401 3 0.017
developmental programmed cell death GO:0010623 4 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
cell projection assembly GO:0030031 64 0.017
protein metabolic process GO:0019538 183 0.017
regulation of protein targeting GO:1903533 2 0.016
sympathetic nervous system development GO:0048485 3 0.016
regeneration GO:0031099 91 0.016
endoplasmic reticulum unfolded protein response GO:0030968 2 0.016
cardiac atrium morphogenesis GO:0003209 2 0.016
regulation of cytokine mediated signaling pathway GO:0001959 3 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
intracellular signal transduction GO:0035556 85 0.016
stem cell proliferation GO:0072089 4 0.016
regionalization GO:0003002 274 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
catabolic process GO:0009056 32 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
small molecule metabolic process GO:0044281 77 0.016
skeletal system morphogenesis GO:0048705 102 0.016
maternal determination of anterior posterior axis embryo GO:0008358 4 0.015
aorta development GO:0035904 4 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
regulation of cardiac muscle cell contraction GO:0086004 1 0.015
positive regulation of hydrolase activity GO:0051345 13 0.015
ribose phosphate metabolic process GO:0019693 27 0.015
regulation of calcium ion transport GO:0051924 2 0.015
cellular modified amino acid metabolic process GO:0006575 3 0.015
cellular localization GO:0051641 97 0.015
cellular response to external stimulus GO:0071496 2 0.015
neuron projection development GO:0031175 180 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
regulation of signaling GO:0023051 235 0.014
cell projection morphogenesis GO:0048858 244 0.014
neural nucleus development GO:0048857 15 0.014
mesenchyme morphogenesis GO:0072132 5 0.014
notochord development GO:0030903 54 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
biosynthetic process GO:0009058 294 0.014
sensory perception GO:0007600 39 0.014
purine containing compound metabolic process GO:0072521 29 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
glial cell migration GO:0008347 3 0.013
action potential GO:0001508 19 0.013
divalent inorganic cation transport GO:0072511 21 0.013
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.013
notochord cell differentiation GO:0060034 18 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
mrna 3 end processing GO:0031124 2 0.013
nuclear import GO:0051170 3 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
regulation of protein depolymerization GO:1901879 1 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.013
lymphoid lineage cell migration into thymus GO:0097535 4 0.013
cardiac atrium development GO:0003230 4 0.013
outflow tract morphogenesis GO:0003151 1 0.013
negative regulation of protein kinase activity GO:0006469 4 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
lens development in camera type eye GO:0002088 22 0.012
cellular cation homeostasis GO:0030003 17 0.012
protein secretion GO:0009306 1 0.012
vascular process in circulatory system GO:0003018 6 0.012
cytoplasm organization GO:0007028 4 0.012
gamete generation GO:0007276 33 0.012
inositol phosphate metabolic process GO:0043647 1 0.012
digestive system process GO:0022600 9 0.012
tissue regeneration GO:0042246 74 0.012
melanin metabolic process GO:0006582 2 0.012
neuroblast proliferation GO:0007405 2 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
purine ribonucleoside biosynthetic process GO:0046129 2 0.012
membrane raft organization GO:0031579 1 0.012
ion homeostasis GO:0050801 41 0.012
cell projection organization GO:0030030 284 0.012
regulation of protein polymerization GO:0032271 2 0.012
purine ribonucleotide metabolic process GO:0009150 27 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
regulation of cell projection assembly GO:0060491 4 0.011
transmembrane transport GO:0055085 120 0.011
regulation of catalytic activity GO:0050790 55 0.011
er nucleus signaling pathway GO:0006984 2 0.011
fin morphogenesis GO:0033334 53 0.011
nucleoside phosphate metabolic process GO:0006753 28 0.011
regulation of transporter activity GO:0032409 2 0.011
protein heterooligomerization GO:0051291 1 0.011
positive regulation of glial cell proliferation GO:0060252 1 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
intestinal cholesterol absorption GO:0030299 2 0.011
phosphorylation GO:0016310 69 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
regulation of positive chemotaxis GO:0050926 4 0.011
lateral line system development GO:0048925 76 0.010
chemical homeostasis GO:0048878 49 0.010
regulation of growth GO:0040008 42 0.010
muscle organ development GO:0007517 101 0.010
regulation of organ growth GO:0046620 3 0.010
cell motility GO:0048870 244 0.010
sodium ion import GO:0097369 3 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
heart trabecula formation GO:0060347 2 0.010
organic substance catabolic process GO:1901575 28 0.010
forebrain anterior posterior pattern specification GO:0021797 3 0.010
embryonic organ morphogenesis GO:0048562 274 0.010
cell part morphogenesis GO:0032990 246 0.010
hematopoietic stem cell differentiation GO:0060218 20 0.010
calcium ion transport GO:0006816 18 0.010
regulation of locomotion GO:0040012 55 0.010
glycosyl compound metabolic process GO:1901657 11 0.010
pronephros development GO:0048793 69 0.010
gtp catabolic process GO:0006184 2 0.010
stem cell maintenance GO:0019827 4 0.010
vasculature development GO:0001944 278 0.010
neural crest cell differentiation GO:0014033 72 0.010

actc1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
hypertrophic cardiomyopathy DOID:11984 0 0.734
myopathy DOID:423 0 0.734
muscular disease DOID:0080000 0 0.734
heart disease DOID:114 0 0.734
cardiomyopathy DOID:0050700 0 0.734
disease of anatomical entity DOID:7 0 0.734
intrinsic cardiomyopathy DOID:0060036 0 0.734
cardiovascular system disease DOID:1287 0 0.734
musculoskeletal system disease DOID:17 0 0.734
muscle tissue disease DOID:66 0 0.734
urinary system cancer DOID:3996 0 0.022
cancer DOID:162 0 0.022
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.022
bone development disease DOID:0080006 0 0.014
bone disease DOID:0080001 0 0.014
connective tissue disease DOID:65 0 0.014
nervous system disease DOID:863 0 0.010