Danio rerio

0 known processes

sirt2

sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae)

(Aliases: wu:fb57d05,zgc:55966,zgc:77003)

sirt2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
endosomal transport GO:0016197 2 0.203
chromosome organization GO:0051276 31 0.142
Mouse
maintenance of location GO:0051235 4 0.119
Mouse
single organism metabolic process GO:0044710 217 0.113
Mouse
larval development GO:0002164 2 0.082
aging GO:0007568 2 0.079
response to chemical GO:0042221 320 0.078
Mouse
meiotic nuclear division GO:0007126 4 0.070
Mouse
single organism organelle organization GO:1902589 199 0.061
Mouse
cellular response to extracellular stimulus GO:0031668 2 0.061
Mouse
single organism localization GO:1902578 225 0.061
Mouse
single organism transport GO:0044765 206 0.058
regulation of organelle assembly GO:1902115 4 0.056
ion transport GO:0006811 114 0.050
regulation of response to stimulus GO:0048583 269 0.050
Mouse
regulation of protein complex assembly GO:0043254 3 0.050
Mouse
meiotic chromosome segregation GO:0045132 3 0.049
negative regulation of chromosome organization GO:2001251 1 0.046
cellular response to external stimulus GO:0071496 2 0.045
Mouse
hormone transport GO:0009914 2 0.045
cellular response to nutrient levels GO:0031669 2 0.043
Mouse
protein import GO:0017038 3 0.043
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.042
modification dependent protein catabolic process GO:0019941 3 0.041
Mouse
nuclear transport GO:0051169 4 0.040
peptide transport GO:0015833 1 0.040
localization of cell GO:0051674 244 0.039
hormone secretion GO:0046879 2 0.038
proteasomal protein catabolic process GO:0010498 2 0.037
Mouse
protein localization to nucleus GO:0034504 3 0.037
transport GO:0006810 220 0.037
multi organism cellular process GO:0044764 2 0.036
autophagy GO:0006914 4 0.035
regionalization GO:0003002 274 0.035
macroautophagy GO:0016236 1 0.034
inorganic anion transport GO:0015698 25 0.034
exocytosis GO:0006887 1 0.034
establishment of protein localization to organelle GO:0072594 4 0.034
organelle organization GO:0006996 227 0.033
Mouse
response to organic substance GO:0010033 153 0.033
Mouse
multicellular organism growth GO:0035264 4 0.033
positive regulation of cellular component biogenesis GO:0044089 3 0.033
cellular response to starvation GO:0009267 1 0.032
Mouse
lipid storage GO:0019915 1 0.032
ion transmembrane transport GO:0034220 91 0.031
modification dependent macromolecule catabolic process GO:0043632 3 0.031
Mouse
viral process GO:0016032 1 0.031
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.030
regulation of reproductive process GO:2000241 4 0.029
Mouse
regulation of protein localization to nucleus GO:1900180 2 0.028
regulation of cellular metabolic process GO:0031323 320 0.028
Mouse
positive regulation of catabolic process GO:0009896 4 0.027
Mouse
regulation of metabolic process GO:0019222 359 0.027
Mouse
positive regulation of secretion GO:0051047 1 0.026
regulation of protein catabolic process GO:0042176 1 0.026
Mouse
covalent chromatin modification GO:0016569 20 0.026
Mouse
endocrine process GO:0050886 2 0.026
gtp metabolic process GO:0046039 4 0.026
regulation of protein transport GO:0051223 3 0.026
rna metabolic process GO:0016070 219 0.025
Mouse
histone modification GO:0016570 20 0.025
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
positive regulation of cellular catabolic process GO:0031331 3 0.024
Mouse
regulation of cell projection assembly GO:0060491 4 0.024
nuclear import GO:0051170 3 0.024
cation transport GO:0006812 81 0.024
protein import into nucleus GO:0006606 3 0.023
inorganic ion transmembrane transport GO:0098660 57 0.023
muscle cell differentiation GO:0042692 139 0.023
regulation of cell shape GO:0008360 1 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.023
Mouse
negative regulation of intracellular transport GO:0032387 3 0.022
locomotion GO:0040011 313 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.022
Mouse
single organism nuclear import GO:1902593 3 0.022
chromatin modification GO:0016568 21 0.022
Mouse
cation transmembrane transport GO:0098655 65 0.022
protein modification process GO:0036211 100 0.022
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.022
Mouse
embryonic heart tube development GO:0035050 133 0.022
cilium morphogenesis GO:0060271 85 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
Mouse
establishment of localization GO:0051234 244 0.021
system process GO:0003008 185 0.021
Mouse
regulation of tube size GO:0035150 2 0.021
peptidyl lysine dimethylation GO:0018027 1 0.021
female meiosis chromosome segregation GO:0016321 1 0.021
regulation of signal transduction GO:0009966 225 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.021
cell motility GO:0048870 244 0.021
cell morphogenesis GO:0000902 289 0.021
actin polymerization or depolymerization GO:0008154 2 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
negative regulation of biological process GO:0048519 304 0.020
Mouse
head development GO:0060322 303 0.020
phosphatidylinositol mediated signaling GO:0048015 2 0.020
cell projection organization GO:0030030 284 0.020
regulation of protein targeting GO:1903533 2 0.020
embryonic organ development GO:0048568 381 0.020
cellular aromatic compound metabolic process GO:0006725 295 0.020
Mouse
positive regulation of transport GO:0051050 2 0.020
protein polyubiquitination GO:0000209 4 0.020
specification of symmetry GO:0009799 204 0.019
negative regulation of cellular catabolic process GO:0031330 3 0.019
cellular modified amino acid metabolic process GO:0006575 3 0.019
amine metabolic process GO:0009308 2 0.019
positive regulation of response to stimulus GO:0048584 80 0.019
biosynthetic process GO:0009058 294 0.019
Mouse
cellular amine metabolic process GO:0044106 2 0.019
regulation of transporter activity GO:0032409 2 0.019
regulation of systemic arterial blood pressure GO:0003073 1 0.019
transmembrane transport GO:0055085 120 0.019
embryonic organ morphogenesis GO:0048562 274 0.019
positive regulation of secretion by cell GO:1903532 1 0.019
peptidyl lysine methylation GO:0018022 3 0.019
regulation of developmental process GO:0050793 247 0.019
Mouse
determination of heart left right asymmetry GO:0061371 117 0.019
cellular lipid catabolic process GO:0044242 3 0.018
Mouse
regulation of histone methylation GO:0031060 3 0.018
muscle cell development GO:0055001 115 0.018
chromatin organization GO:0006325 22 0.018
Mouse
positive regulation of biological process GO:0048518 253 0.018
Mouse
somatic muscle development GO:0007525 4 0.018
brain development GO:0007420 293 0.018
regulation of multicellular organismal development GO:2000026 223 0.018
Mouse
dicarboxylic acid transport GO:0006835 1 0.018
cell substrate adhesion GO:0031589 4 0.018
cytoskeleton organization GO:0007010 96 0.018
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
Mouse
regulation of biological quality GO:0065008 263 0.018
Mouse
regulation of localization GO:0032879 104 0.018
Mouse
circulatory system process GO:0003013 87 0.018
cellular component assembly GO:0022607 170 0.017
Mouse
nitrogen compound metabolic process GO:0006807 319 0.017
Mouse
peptidyl threonine phosphorylation GO:0018107 1 0.017
Mouse
organelle assembly GO:0070925 110 0.017
protein targeting to nucleus GO:0044744 3 0.017
regulation of binding GO:0051098 3 0.017
Mouse
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.017
hemopoiesis GO:0030097 183 0.017
regulation of synapse organization GO:0050807 3 0.017
phagocytosis GO:0006909 3 0.017
actin filament polymerization GO:0030041 2 0.017
multi organism process GO:0051704 134 0.017
Mouse
cellular amino acid metabolic process GO:0006520 7 0.017
cell cell signaling GO:0007267 52 0.017
signal transduction GO:0007165 455 0.017
regulation of protein ubiquitination GO:0031396 3 0.016
cellular macromolecule metabolic process GO:0044260 391 0.016
Mouse
lipid digestion GO:0044241 3 0.016
meiotic spindle organization GO:0000212 1 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
neural crest formation GO:0014029 14 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
cellular component morphogenesis GO:0032989 336 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.016
Mouse
guanosine containing compound metabolic process GO:1901068 4 0.016
muscle structure development GO:0061061 196 0.015
response to monosaccharide GO:0034284 3 0.015
metal ion transport GO:0030001 58 0.015
cellular biosynthetic process GO:0044249 286 0.015
Mouse
response to unfolded protein GO:0006986 2 0.015
cellular protein modification process GO:0006464 100 0.015
Mouse
inositol lipid mediated signaling GO:0048017 2 0.015
negative regulation of metabolic process GO:0009892 86 0.015
Mouse
negative regulation of protein transport GO:0051224 3 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
Mouse
regulation of cytokine production GO:0001817 3 0.015
stem cell maintenance GO:0019827 4 0.015
female meiotic division GO:0007143 2 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
response to amino acid GO:0043200 2 0.015
cytoplasm organization GO:0007028 4 0.015
sequestering of calcium ion GO:0051208 3 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
Mouse
regulation of cell communication GO:0010646 232 0.014
determination of bilateral symmetry GO:0009855 204 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.014
regulation of calcium ion transport GO:0051924 2 0.014
response to carbohydrate GO:0009743 3 0.014
synaptic vesicle transport GO:0048489 1 0.014
sequestering of metal ion GO:0051238 3 0.014
nuclear export GO:0051168 1 0.014
sensory perception of chemical stimulus GO:0007606 3 0.014
macromolecule methylation GO:0043414 19 0.014
regulation of protein polymerization GO:0032271 2 0.014
regulation of synapse assembly GO:0051963 3 0.014
regulation of autophagy GO:0010506 3 0.014
regulation of transmembrane transporter activity GO:0022898 2 0.014
regulation of hormone secretion GO:0046883 2 0.014
nucleobase containing compound metabolic process GO:0006139 274 0.014
Mouse
chloride transmembrane transport GO:1902476 4 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
negative regulation of cytoplasmic transport GO:1903650 2 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
cytosolic calcium ion transport GO:0060401 3 0.014
negative regulation of gene expression GO:0010629 65 0.014
Mouse
homeostatic process GO:0042592 142 0.014
cognition GO:0050890 1 0.014
regulation of chromosome segregation GO:0051983 1 0.014
Mouse
single organism cellular localization GO:1902580 46 0.014
carbohydrate homeostasis GO:0033500 1 0.013
neuroblast proliferation GO:0007405 2 0.013
actin filament based movement GO:0030048 1 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
response to nutrient GO:0007584 3 0.013
interspecies interaction between organisms GO:0044419 4 0.013
striated muscle cell development GO:0055002 108 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
inorganic cation transmembrane transport GO:0098662 50 0.013
cellular component biogenesis GO:0044085 178 0.013
Mouse
regulation of filopodium assembly GO:0051489 2 0.013
immune system process GO:0002376 241 0.013
embryonic heart tube morphogenesis GO:0003143 108 0.013
macromolecule modification GO:0043412 111 0.013
Mouse
positive regulation of cytokine production GO:0001819 2 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
protein secretion GO:0009306 1 0.013
response to stress GO:0006950 263 0.013
Mouse
regulation of muscle contraction GO:0006937 3 0.013
regulation of signaling GO:0023051 235 0.013
protein complex subunit organization GO:0071822 46 0.013
Mouse
cell cycle process GO:0022402 53 0.013
Mouse
membrane invagination GO:0010324 1 0.013
regulation of biosynthetic process GO:0009889 250 0.012
Mouse
double strand break repair GO:0006302 3 0.012
lateral inhibition GO:0046331 1 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
Mouse
mitotic cytokinesis GO:0000281 3 0.012
rna localization GO:0006403 4 0.012
response to glucose GO:0009749 3 0.012
spindle assembly involved in mitosis GO:0090307 1 0.012
regulation of transcription dna templated GO:0006355 213 0.012
Mouse
growth GO:0040007 174 0.012
response to topologically incorrect protein GO:0035966 2 0.012
establishment of localization in cell GO:0051649 77 0.012
nucleocytoplasmic transport GO:0006913 4 0.012
calcium ion transport into cytosol GO:0060402 3 0.012
vacuolar transport GO:0007034 2 0.012
morphogenesis of an epithelium GO:0002009 333 0.012
regulation of blood pressure GO:0008217 1 0.012
heart development GO:0007507 313 0.012
negative regulation of sequestering of calcium ion GO:0051283 4 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
Mouse
fatty acid beta oxidation GO:0006635 1 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.012
negative regulation of catabolic process GO:0009895 3 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
small molecule metabolic process GO:0044281 77 0.012
gene expression GO:0010467 252 0.012
Mouse
negative regulation of blood circulation GO:1903523 2 0.012
protein stabilization GO:0050821 2 0.012
atp synthesis coupled electron transport GO:0042773 1 0.012
regulation of epidermis development GO:0045682 2 0.012
cell surface receptor signaling pathway GO:0007166 325 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
Mouse
regulation of multicellular organism growth GO:0040014 4 0.011
regulation of blood vessel size GO:0050880 2 0.011
mitochondrion organization GO:0007005 4 0.011
response to uv GO:0009411 3 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
digestive system development GO:0055123 289 0.011
actin filament based process GO:0030029 64 0.011
negative regulation of cellular process GO:0048523 283 0.011
Mouse
embryonic limb morphogenesis GO:0030326 2 0.011
oxoacid metabolic process GO:0043436 31 0.011
blood circulation GO:0008015 87 0.011
protein polymerization GO:0051258 4 0.011
regulation of protein metabolic process GO:0051246 56 0.011
Mouse
central nervous system development GO:0007417 387 0.011
cellular response to xenobiotic stimulus GO:0071466 35 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.011
regulation of nitrogen compound metabolic process GO:0051171 251 0.011
Mouse
transcription dna templated GO:0006351 181 0.011
Mouse
organic acid metabolic process GO:0006082 31 0.011
cell migration GO:0016477 237 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
microtubule organizing center organization GO:0031023 1 0.011
negative regulation of protein localization to nucleus GO:1900181 2 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
regulation of cellular component movement GO:0051270 55 0.011
localization within membrane GO:0051668 1 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
tissue remodeling GO:0048771 4 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
Mouse
tube closure GO:0060606 1 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
muscle organ development GO:0007517 101 0.011
response to external stimulus GO:0009605 264 0.011
Mouse
inorganic anion transmembrane transport GO:0098661 10 0.011
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
Mouse
heart morphogenesis GO:0003007 156 0.011
er nucleus signaling pathway GO:0006984 2 0.011
carbohydrate derivative biosynthetic process GO:1901137 43 0.011
regulation of gtp catabolic process GO:0033124 2 0.010
production of molecular mediator of immune response GO:0002440 2 0.010
positive regulation of camp biosynthetic process GO:0030819 2 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.010
alternative mrna splicing via spliceosome GO:0000380 1 0.010
regulation of macromolecule biosynthetic process GO:0010556 225 0.010
Mouse
lipid catabolic process GO:0016042 4 0.010
Mouse
regulation of intracellular ph GO:0051453 1 0.010
response to xenobiotic stimulus GO:0009410 45 0.010
regulation of response to extracellular stimulus GO:0032104 1 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.010
Mouse
signal transduction in absence of ligand GO:0038034 1 0.010
regulation of establishment of planar polarity GO:0090175 4 0.010
cilium assembly GO:0042384 58 0.010
cellular protein catabolic process GO:0044257 4 0.010
Mouse

sirt2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.015
disease of anatomical entity DOID:7 0 0.014