Danio rerio

0 known processes

LOC565459

tight junction protein ZO-1-like

LOC565459 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of biological quality GO:0065008 263 0.398
ameboidal type cell migration GO:0001667 143 0.208
lateral inhibition GO:0046331 1 0.155
cellular response to nutrient levels GO:0031669 2 0.146
cellular response to external stimulus GO:0071496 2 0.121
mesenchyme development GO:0060485 127 0.118
calcium ion transport into cytosol GO:0060402 3 0.101
larval development GO:0002164 2 0.099
regulation of tube size GO:0035150 2 0.094
organic acid metabolic process GO:0006082 31 0.084
collagen biosynthetic process GO:0032964 2 0.078
multicellular organismal metabolic process GO:0044236 2 0.077
heart looping GO:0001947 94 0.075
ras protein signal transduction GO:0007265 7 0.073
adherens junction organization GO:0034332 4 0.068
localization of cell GO:0051674 244 0.066
regulation of signal transduction GO:0009966 225 0.066
regulation of anatomical structure size GO:0090066 33 0.066
single organismal cell cell adhesion GO:0016337 29 0.064
determination of heart left right asymmetry GO:0061371 117 0.064
multicellular organism growth GO:0035264 4 0.063
aging GO:0007568 2 0.062
multicellular organismal macromolecule metabolic process GO:0044259 2 0.058
heart development GO:0007507 313 0.058
heart morphogenesis GO:0003007 156 0.057
cell migration GO:0016477 237 0.054
protein localization GO:0008104 40 0.053
developmental growth involved in morphogenesis GO:0060560 86 0.052
regulation of nervous system development GO:0051960 90 0.052
sequestering of metal ion GO:0051238 3 0.051
regulation of developmental growth GO:0048638 38 0.050
growth GO:0040007 174 0.049
small gtpase mediated signal transduction GO:0007264 8 0.047
cellular response to extracellular stimulus GO:0031668 2 0.045
cell motility GO:0048870 244 0.045
regulation of developmental process GO:0050793 247 0.043
gastrulation GO:0007369 208 0.042
cardiac atrium development GO:0003230 4 0.042
synaptic growth at neuromuscular junction GO:0051124 2 0.041
positive regulation of immune effector process GO:0002699 3 0.040
single organism cell adhesion GO:0098602 29 0.039
digestive system development GO:0055123 289 0.038
morphogenesis of an epithelium GO:0002009 333 0.037
signal transduction GO:0007165 455 0.037
regulation of neurological system process GO:0031644 2 0.037
odontogenesis of dentin containing tooth GO:0042475 1 0.037
cellular response to starvation GO:0009267 1 0.036
organonitrogen compound metabolic process GO:1901564 74 0.035
regulation of multicellular organismal development GO:2000026 223 0.035
muscle structure development GO:0061061 196 0.035
cell morphogenesis GO:0000902 289 0.034
negative regulation of protein phosphorylation GO:0001933 4 0.034
regulation of cell shape GO:0008360 1 0.034
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.033
cell projection organization GO:0030030 284 0.032
embryonic organ development GO:0048568 381 0.031
cell morphogenesis involved in differentiation GO:0000904 195 0.031
determination of left right symmetry GO:0007368 179 0.031
positive regulation of cellular component biogenesis GO:0044089 3 0.030
regulation of synapse organization GO:0050807 3 0.029
cellular protein catabolic process GO:0044257 4 0.029
positive regulation of epithelial cell proliferation GO:0050679 1 0.029
protein targeting to nucleus GO:0044744 3 0.028
response to external stimulus GO:0009605 264 0.028
intracellular signal transduction GO:0035556 85 0.028
nucleocytoplasmic transport GO:0006913 4 0.027
developmental cell growth GO:0048588 52 0.026
regulation of cellular component organization GO:0051128 86 0.026
hepaticobiliary system development GO:0061008 98 0.026
fertilization GO:0009566 3 0.026
regulation of intracellular signal transduction GO:1902531 57 0.026
response to oxygen levels GO:0070482 25 0.026
small molecule metabolic process GO:0044281 77 0.025
single organism metabolic process GO:0044710 217 0.025
head development GO:0060322 303 0.025
chondrocyte development GO:0002063 4 0.025
adult behavior GO:0030534 2 0.024
oxoacid metabolic process GO:0043436 31 0.024
maintenance of location GO:0051235 4 0.024
cation transmembrane transport GO:0098655 65 0.024
regulation of multicellular organismal process GO:0051239 277 0.024
neuron projection morphogenesis GO:0048812 161 0.023
immune system development GO:0002520 191 0.023
regulation of cardiac muscle tissue development GO:0055024 1 0.022
regulation of cell communication GO:0010646 232 0.022
negative regulation of protein transport GO:0051224 3 0.022
mitotic dna integrity checkpoint GO:0044774 4 0.022
macromolecular complex assembly GO:0065003 35 0.022
tube morphogenesis GO:0035239 349 0.022
adherens junction assembly GO:0034333 1 0.022
cell cell junction organization GO:0045216 10 0.022
regulation of establishment of protein localization GO:0070201 4 0.021
proteasomal protein catabolic process GO:0010498 2 0.021
regulation of protein transport GO:0051223 3 0.021
phosphorus metabolic process GO:0006793 109 0.021
regulation of establishment of planar polarity GO:0090175 4 0.021
cellular carbohydrate metabolic process GO:0044262 4 0.021
epithelial tube morphogenesis GO:0060562 148 0.020
organelle localization GO:0051640 49 0.020
pigment granule transport GO:0051904 19 0.020
cell projection morphogenesis GO:0048858 244 0.020
protein homooligomerization GO:0051260 3 0.020
regionalization GO:0003002 274 0.020
dna biosynthetic process GO:0071897 3 0.020
transport GO:0006810 220 0.020
regulation of intracellular protein transport GO:0033157 3 0.019
notochord development GO:0030903 54 0.019
negative regulation of sequestering of calcium ion GO:0051283 4 0.019
regulation of cell adhesion GO:0030155 15 0.019
cytosolic calcium ion transport GO:0060401 3 0.019
synaptic transmission GO:0007268 35 0.019
regulation of heart growth GO:0060420 2 0.019
regulation of anatomical structure morphogenesis GO:0022603 130 0.019
nuclear transport GO:0051169 4 0.019
cellular component assembly GO:0022607 170 0.018
gtp catabolic process GO:0006184 2 0.018
regulation of myotube differentiation GO:0010830 2 0.018
regulation of cellular component movement GO:0051270 55 0.018
guanosine containing compound catabolic process GO:1901069 2 0.017
protein complex disassembly GO:0043241 1 0.017
muscle cell differentiation GO:0042692 139 0.017
locomotion GO:0040011 313 0.017
phosphate containing compound metabolic process GO:0006796 108 0.017
cell surface receptor signaling pathway GO:0007166 325 0.017
regulation of cellular metabolic process GO:0031323 320 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
cellular component disassembly GO:0022411 1 0.016
negative regulation of kinase activity GO:0033673 4 0.016
embryonic viscerocranium morphogenesis GO:0048703 52 0.016
lipid storage GO:0019915 1 0.016
anterior posterior pattern specification GO:0009952 152 0.016
macromolecular complex disassembly GO:0032984 1 0.016
positive regulation of synapse assembly GO:0051965 1 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
taxis GO:0042330 109 0.016
vascular process in circulatory system GO:0003018 6 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
regulation of metal ion transport GO:0010959 4 0.016
cellular component morphogenesis GO:0032989 336 0.016
regulation of embryonic development GO:0045995 47 0.015
response to stress GO:0006950 263 0.015
gtp metabolic process GO:0046039 4 0.015
regulation of blood vessel size GO:0050880 2 0.015
neural crest cell migration GO:0001755 42 0.015
cellular component biogenesis GO:0044085 178 0.015
neuron projection development GO:0031175 180 0.015
cellular protein modification process GO:0006464 100 0.015
eye development GO:0001654 277 0.015
sensory organ development GO:0007423 393 0.015
smooth muscle contraction GO:0006939 2 0.015
tissue migration GO:0090130 37 0.014
cellular response to radiation GO:0071478 4 0.014
regulation of rho protein signal transduction GO:0035023 2 0.014
vasculature development GO:0001944 278 0.014
regulation of extent of cell growth GO:0061387 29 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
digestive tract development GO:0048565 265 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.014
protein import GO:0017038 3 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
regulation of cell development GO:0060284 100 0.013
response to abiotic stimulus GO:0009628 122 0.013
amine metabolic process GO:0009308 2 0.013
protein import into nucleus GO:0006606 3 0.013
somite development GO:0061053 96 0.013
regulation of cell cell adhesion GO:0022407 13 0.013
cellular nitrogen compound metabolic process GO:0034641 290 0.013
regulation of reproductive process GO:2000241 4 0.013
respiratory system development GO:0060541 5 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
nuclear import GO:0051170 3 0.013
determination of bilateral symmetry GO:0009855 204 0.012
regulation of cell projection organization GO:0031344 44 0.012
neuron projection extension GO:1990138 45 0.012
neural crest cell development GO:0014032 62 0.012
cardiac chamber development GO:0003205 19 0.012
ventricular cardiac muscle tissue development GO:0003229 3 0.012
primary neural tube formation GO:0014020 1 0.012
regulation of organ growth GO:0046620 3 0.012
behavior GO:0007610 74 0.012
response to decreased oxygen levels GO:0036293 25 0.012
cellular response to hypoxia GO:0071456 1 0.012
axon ensheathment in central nervous system GO:0032291 2 0.012
g protein coupled receptor signaling pathway GO:0007186 74 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
alpha amino acid metabolic process GO:1901605 3 0.011
cell part morphogenesis GO:0032990 246 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.011
macromolecule localization GO:0033036 54 0.011
regulation of response to stimulus GO:0048583 269 0.011
rho protein signal transduction GO:0007266 5 0.011
cell substrate junction assembly GO:0007044 2 0.011
cellular component movement GO:0006928 335 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
convergent extension GO:0060026 118 0.011
aminoglycan metabolic process GO:0006022 9 0.011
sensory perception of pain GO:0019233 1 0.011
protein secretion GO:0009306 1 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
interaction with host GO:0051701 4 0.011
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.011
developmental growth GO:0048589 166 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
mesenchymal cell development GO:0014031 78 0.010
response to chemical GO:0042221 320 0.010
axon extension GO:0048675 45 0.010
fin morphogenesis GO:0033334 53 0.010
regulation of blood circulation GO:1903522 32 0.010
guanosine containing compound metabolic process GO:1901068 4 0.010
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
epithelial cell morphogenesis GO:0003382 2 0.010
regulation of growth GO:0040008 42 0.010
regulation of cytoplasmic transport GO:1903649 4 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010

LOC565459 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.055
cardiovascular system disease DOID:1287 0 0.045
musculoskeletal system disease DOID:17 0 0.028
connective tissue disease DOID:65 0 0.014
myopathy DOID:423 0 0.014
muscular disease DOID:0080000 0 0.014
heart disease DOID:114 0 0.014
cardiomyopathy DOID:0050700 0 0.014
intrinsic cardiomyopathy DOID:0060036 0 0.014
muscle tissue disease DOID:66 0 0.014
disease of cellular proliferation DOID:14566 0 0.012
bone disease DOID:0080001 0 0.012