Danio rerio

0 known processes

nle1

notchless homolog 1 (Drosophila)

(Aliases: fc12b09,zgc:110281,wu:fc12b09,MGC110281,fc45f01,wu:fc45f01)

nle1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.213
Worm
nitrogen compound metabolic process GO:0006807 319 0.117
aging GO:0007568 2 0.103
cellular macromolecule metabolic process GO:0044260 391 0.081
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.078
chordate embryonic development GO:0043009 271 0.077
Mouse
lipid storage GO:0019915 1 0.075
Worm
cellular nitrogen compound biosynthetic process GO:0044271 218 0.073
multicellular organism growth GO:0035264 4 0.071
signal transduction GO:0007165 455 0.069
Mouse
negative regulation of cellular process GO:0048523 283 0.069
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.069
regulation of response to stimulus GO:0048583 269 0.065
Mouse
heterocycle biosynthetic process GO:0018130 215 0.064
rna metabolic process GO:0016070 219 0.061
response to nutrient GO:0007584 3 0.056
embryo development ending in birth or egg hatching GO:0009792 271 0.054
Mouse
reproduction GO:0000003 40 0.052
Worm
regulation of multicellular organism growth GO:0040014 4 0.052
ribosomal small subunit biogenesis GO:0042274 2 0.051
heterocycle metabolic process GO:0046483 290 0.047
generation of neurons GO:0048699 385 0.046
cellular aromatic compound metabolic process GO:0006725 295 0.045
organic cyclic compound biosynthetic process GO:1901362 223 0.045
locomotion GO:0040011 313 0.042
morphogenesis of an epithelium GO:0002009 333 0.041
cellular modified amino acid metabolic process GO:0006575 3 0.041
cellular amino acid metabolic process GO:0006520 7 0.041
regulation of rna biosynthetic process GO:2001141 213 0.040
cellular response to starvation GO:0009267 1 0.039
biosynthetic process GO:0009058 294 0.038
nucleobase containing compound biosynthetic process GO:0034654 205 0.038
small molecule metabolic process GO:0044281 77 0.037
organic substance biosynthetic process GO:1901576 289 0.037
cellular response to external stimulus GO:0071496 2 0.036
localization of cell GO:0051674 244 0.035
meiotic nuclear division GO:0007126 4 0.034
nucleocytoplasmic transport GO:0006913 4 0.034
cellular response to extracellular stimulus GO:0031668 2 0.033
muscle tissue development GO:0060537 110 0.033
cellular response to nutrient levels GO:0031669 2 0.033
apoptotic process GO:0006915 116 0.033
Mouse
tube morphogenesis GO:0035239 349 0.033
regulation of cell communication GO:0010646 232 0.032
Mouse
macromolecule biosynthetic process GO:0009059 227 0.032
tissue remodeling GO:0048771 4 0.032
aromatic compound biosynthetic process GO:0019438 217 0.031
single organism reproductive process GO:0044702 40 0.031
organelle organization GO:0006996 227 0.031
Yeast
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.030
phagocytosis GO:0006909 3 0.030
response to chemical GO:0042221 320 0.030
central nervous system development GO:0007417 387 0.029
cognition GO:0050890 1 0.029
regulation of biosynthetic process GO:0009889 250 0.029
nucleic acid metabolic process GO:0090304 244 0.027
vasculature development GO:0001944 278 0.027
gene expression GO:0010467 252 0.027
Mouse
multi organism process GO:0051704 134 0.027
protein targeting to nucleus GO:0044744 3 0.027
establishment of localization GO:0051234 244 0.027
Worm
cell migration GO:0016477 237 0.026
positive regulation of transport GO:0051050 2 0.026
head development GO:0060322 303 0.026
maturation of ssu rrna GO:0030490 1 0.026
protein import into nucleus GO:0006606 3 0.026
muscle structure development GO:0061061 196 0.026
nucleobase containing compound metabolic process GO:0006139 274 0.026
organonitrogen compound metabolic process GO:1901564 74 0.026
nuclear import GO:0051170 3 0.025
synaptic growth at neuromuscular junction GO:0051124 2 0.025
cellular biosynthetic process GO:0044249 286 0.025
positive regulation of cellular component biogenesis GO:0044089 3 0.024
regulation of biological quality GO:0065008 263 0.024
Mouse Worm
oxoacid metabolic process GO:0043436 31 0.024
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.024
regulation of skeletal muscle tissue development GO:0048641 4 0.024
response to amino acid GO:0043200 2 0.023
regulation of cellular metabolic process GO:0031323 320 0.023
Mouse
regulation of signal transduction GO:0009966 225 0.023
Mouse
response to drug GO:0042493 3 0.023
system process GO:0003008 185 0.023
response to stress GO:0006950 263 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.023
single organism metabolic process GO:0044710 217 0.023
response to carbohydrate GO:0009743 3 0.022
maintenance of location GO:0051235 4 0.022
Worm
muscle cell differentiation GO:0042692 139 0.022
cellular component disassembly GO:0022411 1 0.022
cellular macromolecule biosynthetic process GO:0034645 224 0.022
enzyme linked receptor protein signaling pathway GO:0007167 106 0.022
embryonic organ development GO:0048568 381 0.021
blood vessel morphogenesis GO:0048514 216 0.021
cell motility GO:0048870 244 0.021
cell death GO:0008219 121 0.021
Mouse
pancreas development GO:0031016 84 0.021
response to ketone GO:1901654 1 0.021
response to organic substance GO:0010033 153 0.021
organic acid metabolic process GO:0006082 31 0.020
eye morphogenesis GO:0048592 144 0.020
rna transport GO:0050658 2 0.020
alpha amino acid metabolic process GO:1901605 3 0.020
regulation of metal ion transport GO:0010959 4 0.020
reproductive process GO:0022414 40 0.020
determination of bilateral symmetry GO:0009855 204 0.020
gamete generation GO:0007276 33 0.020
regulation of calcium ion transport GO:0051924 2 0.019
nucleic acid templated transcription GO:0097659 181 0.019
cellular response to oxygen levels GO:0071453 1 0.019
cell cycle g1 s phase transition GO:0044843 1 0.019
skeletal system development GO:0001501 181 0.019
positive regulation of cell cycle GO:0045787 3 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
transport GO:0006810 220 0.019
Worm
blood circulation GO:0008015 87 0.019
single organism biosynthetic process GO:0044711 71 0.019
cellular component assembly involved in morphogenesis GO:0010927 107 0.019
regulation of dna replication GO:0006275 3 0.019
programmed cell death GO:0012501 119 0.019
Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.018
response to endogenous stimulus GO:0009719 83 0.018
regulation of developmental process GO:0050793 247 0.018
regulation of rna metabolic process GO:0051252 224 0.018
response to monosaccharide GO:0034284 3 0.018
nucleobase containing compound transport GO:0015931 2 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
regulation of transcription dna templated GO:0006355 213 0.018
camera type eye development GO:0043010 222 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
regulation of neural precursor cell proliferation GO:2000177 3 0.018
g2 dna damage checkpoint GO:0031572 3 0.018
rna biosynthetic process GO:0032774 181 0.018
blood vessel development GO:0001568 246 0.018
response to corticosteroid GO:0031960 1 0.018
digestive system development GO:0055123 289 0.018
angiogenesis GO:0001525 158 0.017
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
meiotic cell cycle process GO:1903046 3 0.017
intracellular signal transduction GO:0035556 85 0.017
single organism nuclear import GO:1902593 3 0.017
lymphocyte proliferation GO:0046651 1 0.017
regulation of signaling GO:0023051 235 0.017
Mouse
immune system process GO:0002376 241 0.017
homeostatic process GO:0042592 142 0.017
Mouse
determination of left right symmetry GO:0007368 179 0.017
neuron differentiation GO:0030182 353 0.017
amine metabolic process GO:0009308 2 0.017
brain development GO:0007420 293 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
regulation of establishment of protein localization GO:0070201 4 0.016
transcription dna templated GO:0006351 181 0.016
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
cell part morphogenesis GO:0032990 246 0.016
specification of symmetry GO:0009799 204 0.016
regulation of protein transport GO:0051223 3 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
nuclear export GO:0051168 1 0.016
hepaticobiliary system development GO:0061008 98 0.016
regulation of binding GO:0051098 3 0.016
protein import GO:0017038 3 0.015
regulation of metabolic process GO:0019222 359 0.015
Mouse
nucleic acid transport GO:0050657 2 0.015
protein localization to nucleus GO:0034504 3 0.015
rna localization GO:0006403 4 0.015
positive regulation of muscle organ development GO:0048636 1 0.015
positive regulation of biological process GO:0048518 253 0.015
Mouse
heart development GO:0007507 313 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
organonitrogen compound biosynthetic process GO:1901566 47 0.015
nuclear transport GO:0051169 4 0.015
death GO:0016265 121 0.015
Mouse
neurotransmitter transport GO:0006836 2 0.014
positive regulation of translation GO:0045727 1 0.014
response to organic cyclic compound GO:0014070 51 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
single organism organelle organization GO:1902589 199 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
Mouse
gland development GO:0048732 143 0.014
response to external stimulus GO:0009605 264 0.014
mitotic dna damage checkpoint GO:0044773 4 0.014
regulation of cytokine production GO:0001817 3 0.014
cartilage development GO:0051216 96 0.014
eye development GO:0001654 277 0.014
response to glucose GO:0009749 3 0.013
negative regulation of biological process GO:0048519 304 0.013
Mouse
striated muscle tissue development GO:0014706 110 0.013
regulation of protein targeting GO:1903533 2 0.013
behavior GO:0007610 74 0.013
multi organism reproductive process GO:0044703 36 0.013
anterior posterior pattern specification GO:0009952 152 0.013
cell cycle arrest GO:0007050 1 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
gastrulation GO:0007369 208 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
cell cycle GO:0007049 93 0.013
Mouse
multicellular organism reproduction GO:0032504 35 0.013
establishment of rna localization GO:0051236 3 0.013
muscle cell development GO:0055001 115 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
retina development in camera type eye GO:0060041 146 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
developmental growth GO:0048589 166 0.013
ribosome assembly GO:0042255 1 0.013
Yeast
stem cell proliferation GO:0072089 4 0.013
cellular response to organic substance GO:0071310 105 0.013
connective tissue development GO:0061448 99 0.013
regulation of primary metabolic process GO:0080090 311 0.013
Mouse
regulation of cell shape GO:0008360 1 0.012
sensory organ development GO:0007423 393 0.012
negative regulation of histone modification GO:0031057 1 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
multicellular organismal response to stress GO:0033555 2 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
circulatory system process GO:0003013 87 0.012
pyrimidine containing compound metabolic process GO:0072527 3 0.012
leukocyte proliferation GO:0070661 1 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
mesenchymal cell differentiation GO:0048762 87 0.012
spindle assembly GO:0051225 2 0.012
segmentation GO:0035282 97 0.012
regulation of protein complex assembly GO:0043254 3 0.012
regulation of reproductive process GO:2000241 4 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
meiotic chromosome segregation GO:0045132 3 0.012
multicellular organismal reproductive process GO:0048609 35 0.012
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.011
cell proliferation GO:0008283 80 0.011
regulation of gene expression GO:0010468 265 0.011
Mouse
gtp metabolic process GO:0046039 4 0.011
atp catabolic process GO:0006200 4 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
Mouse
positive regulation of muscle tissue development GO:1901863 1 0.011
embryonic skeletal joint development GO:0072498 3 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
cellular ketone metabolic process GO:0042180 11 0.011
negative regulation of defense response GO:0031348 2 0.011
response to acid chemical GO:0001101 17 0.011
mitotic g2 m transition checkpoint GO:0044818 3 0.011
carbohydrate homeostasis GO:0033500 1 0.011
single organism transport GO:0044765 206 0.011
protein complex disassembly GO:0043241 1 0.011
response to oxygen containing compound GO:1901700 55 0.011
sexual reproduction GO:0019953 36 0.011
regulation of cell activation GO:0050865 1 0.011
rna export from nucleus GO:0006405 1 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
skeletal muscle organ development GO:0060538 78 0.011
cell aging GO:0007569 2 0.011
negative regulation of kinase activity GO:0033673 4 0.011
b cell activation GO:0042113 2 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
single organism localization GO:1902578 225 0.011
membrane invagination GO:0010324 1 0.010
cellular response to decreased oxygen levels GO:0036294 1 0.010
embryonic skeletal system morphogenesis GO:0048704 93 0.010
somite development GO:0061053 96 0.010
modification dependent macromolecule catabolic process GO:0043632 3 0.010
cell fate specification GO:0001708 68 0.010
regulation of multicellular organismal development GO:2000026 223 0.010
organelle assembly GO:0070925 110 0.010
Yeast
phagocytosis engulfment GO:0006911 1 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010
determination of heart left right asymmetry GO:0061371 117 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.010
positive regulation of striated muscle tissue development GO:0045844 1 0.010
retina morphogenesis in camera type eye GO:0060042 79 0.010
ncrna metabolic process GO:0034660 12 0.010

nle1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.018
sensory system disease DOID:0050155 0 0.012
nervous system disease DOID:863 0 0.012