Danio rerio

0 known processes

phb2

prohibitin 2

(Aliases: wu:fc28c08,zgc:73150,bcap37)

phb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitochondrion organization GO:0007005 4 0.809
larval development GO:0002164 2 0.317
cellular protein catabolic process GO:0044257 4 0.188
cellular nitrogen compound metabolic process GO:0034641 290 0.143
transcription dna templated GO:0006351 181 0.107
regulation of transcription dna templated GO:0006355 213 0.106
multicellular organism growth GO:0035264 4 0.086
cellular macromolecule biosynthetic process GO:0034645 224 0.085
organic cyclic compound metabolic process GO:1901360 301 0.084
macromolecule biosynthetic process GO:0009059 227 0.083
response to stress GO:0006950 263 0.081
organic substance biosynthetic process GO:1901576 289 0.078
rna metabolic process GO:0016070 219 0.077
regulation of multicellular organism growth GO:0040014 4 0.067
transport GO:0006810 220 0.065
organelle organization GO:0006996 227 0.061
regulation of multicellular organismal process GO:0051239 277 0.060
nitrogen compound metabolic process GO:0006807 319 0.060
regulation of nucleic acid templated transcription GO:1903506 213 0.058
organic cyclic compound biosynthetic process GO:1901362 223 0.058
aging GO:0007568 2 0.057
regulation of developmental process GO:0050793 247 0.056
aromatic compound biosynthetic process GO:0019438 217 0.056
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.056
cellular aromatic compound metabolic process GO:0006725 295 0.055
mitochondrial transport GO:0006839 2 0.053
rna biosynthetic process GO:0032774 181 0.051
protein metabolic process GO:0019538 183 0.050
cellular biosynthetic process GO:0044249 286 0.050
nucleic acid templated transcription GO:0097659 181 0.049
regulation of rna metabolic process GO:0051252 224 0.048
nucleobase containing compound biosynthetic process GO:0034654 205 0.043
regulation of primary metabolic process GO:0080090 311 0.042
cellular component assembly GO:0022607 170 0.042
nucleobase containing compound metabolic process GO:0006139 274 0.041
nucleoside monophosphate catabolic process GO:0009125 4 0.041
heterocycle biosynthetic process GO:0018130 215 0.041
heterocycle metabolic process GO:0046483 290 0.041
biosynthetic process GO:0009058 294 0.039
single fertilization GO:0007338 3 0.039
lipid storage GO:0019915 1 0.039
cellular macromolecule metabolic process GO:0044260 391 0.039
regulation of macromolecule biosynthetic process GO:0010556 225 0.038
regulation of gene expression GO:0010468 265 0.038
positive regulation of biological process GO:0048518 253 0.038
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.038
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.038
response to chemical GO:0042221 320 0.037
regulation of nucleoside metabolic process GO:0009118 2 0.035
single organism localization GO:1902578 225 0.035
positive regulation of cell cycle GO:0045787 3 0.035
establishment of protein localization to organelle GO:0072594 4 0.035
nucleic acid metabolic process GO:0090304 244 0.034
development of primary female sexual characteristics GO:0046545 4 0.032
female gonad development GO:0008585 4 0.032
regulation of rna biosynthetic process GO:2001141 213 0.030
signal transduction GO:0007165 455 0.030
central nervous system development GO:0007417 387 0.030
response to topologically incorrect protein GO:0035966 2 0.030
cellular protein metabolic process GO:0044267 129 0.030
protein secretion GO:0009306 1 0.029
gene expression GO:0010467 252 0.028
regulation of signal transduction GO:0009966 225 0.027
female sex differentiation GO:0046660 4 0.027
cell migration GO:0016477 237 0.026
establishment of localization GO:0051234 244 0.026
single organism organelle organization GO:1902589 199 0.026
regulation of cell activation GO:0050865 1 0.026
ubiquitin dependent protein catabolic process GO:0006511 3 0.026
ovulation cycle GO:0042698 2 0.025
cellular component biogenesis GO:0044085 178 0.025
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
maintenance of location GO:0051235 4 0.025
modification dependent macromolecule catabolic process GO:0043632 3 0.025
regulation of biological quality GO:0065008 263 0.024
death GO:0016265 121 0.024
regulation of biosynthetic process GO:0009889 250 0.024
cell motility GO:0048870 244 0.023
positive regulation of apoptotic signaling pathway GO:2001235 1 0.023
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
developmental growth GO:0048589 166 0.022
protein import GO:0017038 3 0.022
growth GO:0040007 174 0.022
negative regulation of biological process GO:0048519 304 0.021
cellular lipid catabolic process GO:0044242 3 0.021
negative regulation of signal transduction GO:0009968 94 0.021
programmed cell death GO:0012501 119 0.021
fin regeneration GO:0031101 51 0.020
protein polyubiquitination GO:0000209 4 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
oxidative phosphorylation GO:0006119 1 0.020
phosphate containing compound metabolic process GO:0006796 108 0.020
response to drug GO:0042493 3 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
embryo development ending in birth or egg hatching GO:0009792 271 0.020
regulation of cellular metabolic process GO:0031323 320 0.020
lipid oxidation GO:0034440 1 0.019
stem cell maintenance GO:0019827 4 0.019
cell death GO:0008219 121 0.019
regulation of meiotic cell cycle GO:0051445 1 0.019
atp catabolic process GO:0006200 4 0.019
fatty acid beta oxidation GO:0006635 1 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
response to organic substance GO:0010033 153 0.018
regulation of developmental growth GO:0048638 38 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.018
carboxylic acid catabolic process GO:0046395 3 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.017
i kappab kinase nf kappab signaling GO:0007249 4 0.017
cellular protein modification process GO:0006464 100 0.017
negative regulation of cellular process GO:0048523 283 0.017
estrogen metabolic process GO:0008210 2 0.017
gtp metabolic process GO:0046039 4 0.017
organonitrogen compound metabolic process GO:1901564 74 0.017
cellular lipid metabolic process GO:0044255 36 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
negative regulation of signaling GO:0023057 96 0.017
cellular component movement GO:0006928 335 0.017
single organism transport GO:0044765 206 0.017
hepaticobiliary system development GO:0061008 98 0.017
system process GO:0003008 185 0.017
microtubule polymerization or depolymerization GO:0031109 3 0.017
gtp catabolic process GO:0006184 2 0.017
macromolecular complex subunit organization GO:0043933 74 0.017
cellular response to nutrient levels GO:0031669 2 0.017
regulation of metabolic process GO:0019222 359 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.017
immune system development GO:0002520 191 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
glycerophospholipid biosynthetic process GO:0046474 1 0.017
transmembrane transport GO:0055085 120 0.016
oxoacid metabolic process GO:0043436 31 0.016
cellular response to stress GO:0033554 62 0.016
small molecule catabolic process GO:0044282 3 0.016
fertilization GO:0009566 3 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.016
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.016
proteolysis GO:0006508 38 0.016
head development GO:0060322 303 0.016
cellular component morphogenesis GO:0032989 336 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
cellular response to hypoxia GO:0071456 1 0.015
regulation of protein targeting GO:1903533 2 0.015
negative regulation of kinase activity GO:0033673 4 0.015
mitochondrion morphogenesis GO:0070584 2 0.015
determination of bilateral symmetry GO:0009855 204 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
establishment of synaptic vesicle localization GO:0097480 1 0.015
cellular catabolic process GO:0044248 27 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
single organism metabolic process GO:0044710 217 0.015
cellular response to oxygen levels GO:0071453 1 0.015
cellular localization GO:0051641 97 0.015
negative regulation of macromolecule metabolic process GO:0010605 76 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
regulation of gtp catabolic process GO:0033124 2 0.014
carbohydrate derivative biosynthetic process GO:1901137 43 0.014
organic acid catabolic process GO:0016054 3 0.014
multi organism process GO:0051704 134 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
apoptotic process GO:0006915 116 0.014
gland development GO:0048732 143 0.014
cellular response to organic substance GO:0071310 105 0.014
protein stabilization GO:0050821 2 0.014
small molecule metabolic process GO:0044281 77 0.014
negative regulation of defense response GO:0031348 2 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
lipid catabolic process GO:0016042 4 0.014
regulation of cell communication GO:0010646 232 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
cell cell recognition GO:0009988 1 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.014
immune system process GO:0002376 241 0.013
lipid homeostasis GO:0055088 3 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
phosphorus metabolic process GO:0006793 109 0.013
negative regulation of gene expression GO:0010629 65 0.013
negative regulation of cell communication GO:0010648 96 0.013
blood vessel morphogenesis GO:0048514 216 0.013
protein modification process GO:0036211 100 0.013
hematopoietic or lymphoid organ development GO:0048534 191 0.013
positive regulation of transport GO:0051050 2 0.013
muscle cell development GO:0055001 115 0.013
determination of left right symmetry GO:0007368 179 0.013
establishment of localization in cell GO:0051649 77 0.013
liver development GO:0001889 96 0.013
embryonic pattern specification GO:0009880 44 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
regulation of protein catabolic process GO:0042176 1 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.012
fatty acid oxidation GO:0019395 1 0.012
very long chain fatty acid metabolic process GO:0000038 4 0.012
organic acid metabolic process GO:0006082 31 0.012
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.012
protein homooligomerization GO:0051260 3 0.012
response to abiotic stimulus GO:0009628 122 0.012
macromolecule deacylation GO:0098732 3 0.012
lipid metabolic process GO:0006629 52 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
intracellular signal transduction GO:0035556 85 0.011
tissue remodeling GO:0048771 4 0.011
regulation of programmed cell death GO:0043067 101 0.011
microtubule based process GO:0007017 60 0.011
organism emergence from protective structure GO:0071684 4 0.011
specification of symmetry GO:0009799 204 0.011
hemopoiesis GO:0030097 183 0.011
endoplasmic reticulum unfolded protein response GO:0030968 2 0.011
positive regulation of developmental process GO:0051094 50 0.011
toxin transport GO:1901998 2 0.011
response to unfolded protein GO:0006986 2 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
monocarboxylic acid catabolic process GO:0072329 3 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.011
sexual reproduction GO:0019953 36 0.011
regulation of binding GO:0051098 3 0.011
protein complex assembly GO:0006461 30 0.011
cellular response to external stimulus GO:0071496 2 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
regulation of nitrogen compound metabolic process GO:0051171 251 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
macromolecule modification GO:0043412 111 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
regulation of signaling GO:0023051 235 0.011
negative regulation of nodal signaling pathway GO:1900108 4 0.011
multicellular organismal signaling GO:0035637 22 0.010
regulation of macromolecule metabolic process GO:0060255 317 0.010
cellular response to topologically incorrect protein GO:0035967 2 0.010
phosphorylation GO:0016310 69 0.010
cellular respiration GO:0045333 3 0.010
catabolic process GO:0009056 32 0.010
er nucleus signaling pathway GO:0006984 2 0.010
reactive oxygen species biosynthetic process GO:1903409 1 0.010
negative regulation of immune response GO:0050777 2 0.010
cytokinesis GO:0000910 3 0.010
dna biosynthetic process GO:0071897 3 0.010
oxidation reduction process GO:0055114 41 0.010
membrane lipid biosynthetic process GO:0046467 2 0.010
cytoskeleton organization GO:0007010 96 0.010

phb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.045
inherited metabolic disorder DOID:655 0 0.045
cancer DOID:162 0 0.029
disease of cellular proliferation DOID:14566 0 0.029
organ system cancer DOID:0050686 0 0.029
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.014