Danio rerio

24 known processes

hspa9

heat shock protein 9

(Aliases: crs,wu:fc27c10,MGC86654,hspa9b,wu:fc14d08,wu:fc38a06,cb740)

hspa9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.727
Worm
mitochondrion morphogenesis GO:0070584 2 0.655
aromatic compound biosynthetic process GO:0019438 217 0.606
organic cyclic compound metabolic process GO:1901360 301 0.603
cellular component morphogenesis GO:0032989 336 0.520
cellular nitrogen compound metabolic process GO:0034641 290 0.479
regulation of nucleic acid templated transcription GO:1903506 213 0.478
organic substance biosynthetic process GO:1901576 289 0.471
gene expression GO:0010467 252 0.449
regulation of gene expression GO:0010468 265 0.396
nucleobase containing compound biosynthetic process GO:0034654 205 0.388
dicarboxylic acid metabolic process GO:0043648 1 0.386
cellular respiration GO:0045333 3 0.367
mitochondrial transport GO:0006839 2 0.365
organic cyclic compound biosynthetic process GO:1901362 223 0.363
aging GO:0007568 2 0.357
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.349
biosynthetic process GO:0009058 294 0.341
cellular nitrogen compound biosynthetic process GO:0044271 218 0.336
cellular biosynthetic process GO:0044249 286 0.329
mitochondrion organization GO:0007005 4 0.327
heterocycle biosynthetic process GO:0018130 215 0.320
embryo development ending in birth or egg hatching GO:0009792 271 0.319
Worm
locomotion GO:0040011 313 0.306
heterocycle metabolic process GO:0046483 290 0.305
endoplasmic reticulum unfolded protein response GO:0030968 2 0.297
Worm
transcription dna templated GO:0006351 181 0.291
cell motility GO:0048870 244 0.285
cell migration GO:0016477 237 0.282
regulation of metabolic process GO:0019222 359 0.278
cellular aromatic compound metabolic process GO:0006725 295 0.275
death GO:0016265 121 0.263
nitrogen compound metabolic process GO:0006807 319 0.253
single organism metabolic process GO:0044710 217 0.248
cellular component movement GO:0006928 335 0.229
macromolecule biosynthetic process GO:0009059 227 0.215
establishment of protein localization to organelle GO:0072594 4 0.202
regulation of nitrogen compound metabolic process GO:0051171 251 0.202
organelle organization GO:0006996 227 0.202
carboxylic acid metabolic process GO:0019752 22 0.188
rna biosynthetic process GO:0032774 181 0.187
nucleic acid metabolic process GO:0090304 244 0.186
response to organic substance GO:0010033 153 0.185
Worm
single organism localization GO:1902578 225 0.177
Mouse
localization of cell GO:0051674 244 0.174
regulation of apoptotic process GO:0042981 98 0.171
zymogen activation GO:0031638 3 0.169
response to unfolded protein GO:0006986 2 0.165
Worm
programmed cell death GO:0012501 119 0.161
single organism organelle organization GO:1902589 199 0.151
nucleic acid templated transcription GO:0097659 181 0.142
negative regulation of cellular process GO:0048523 283 0.142
cell death GO:0008219 121 0.139
negative regulation of biological process GO:0048519 304 0.138
nucleobase containing compound metabolic process GO:0006139 274 0.136
cellular component biogenesis GO:0044085 178 0.131
regulation of macromolecule biosynthetic process GO:0010556 225 0.130
cellular macromolecule biosynthetic process GO:0034645 224 0.129
positive regulation of type i interferon production GO:0032481 1 0.128
establishment of localization GO:0051234 244 0.127
Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.124
system process GO:0003008 185 0.124
regulation of rna biosynthetic process GO:2001141 213 0.123
regulation of primary metabolic process GO:0080090 311 0.120
single organism biosynthetic process GO:0044711 71 0.120
regulation of biosynthetic process GO:0009889 250 0.119
intracellular receptor signaling pathway GO:0030522 30 0.116
positive regulation of metabolic process GO:0009893 108 0.113
rna metabolic process GO:0016070 219 0.110
cellular macromolecule metabolic process GO:0044260 391 0.101
response to chemical GO:0042221 320 0.092
Worm
regulation of multicellular organismal process GO:0051239 277 0.091
intracellular transport GO:0046907 32 0.090
Mouse
response to external stimulus GO:0009605 264 0.088
intracellular steroid hormone receptor signaling pathway GO:0030518 5 0.086
small molecule metabolic process GO:0044281 77 0.085
cellular component assembly GO:0022607 170 0.085
single organism intracellular transport GO:1902582 25 0.084
Mouse
sulfur compound biosynthetic process GO:0044272 9 0.082
transport GO:0006810 220 0.078
Mouse
purine nucleoside monophosphate metabolic process GO:0009126 5 0.078
negative regulation of metabolic process GO:0009892 86 0.078
positive regulation of cellular metabolic process GO:0031325 94 0.077
oxoacid metabolic process GO:0043436 31 0.077
nuclear transport GO:0051169 4 0.076
Mouse
hemopoiesis GO:0030097 183 0.076
regeneration GO:0031099 91 0.076
regulation of cellular biosynthetic process GO:0031326 245 0.075
b cell activation GO:0042113 2 0.074
leukocyte proliferation GO:0070661 1 0.072
regulation of rna metabolic process GO:0051252 224 0.071
immune system development GO:0002520 191 0.070
regulation of transcription dna templated GO:0006355 213 0.069
apoptotic process GO:0006915 116 0.068
response to biotic stimulus GO:0009607 97 0.068
circadian sleep wake cycle GO:0042745 2 0.067
signal transduction GO:0007165 455 0.065
Worm
regulation of programmed cell death GO:0043067 101 0.065
regulation of tube size GO:0035150 2 0.063
regulation of macromolecule metabolic process GO:0060255 317 0.063
cellular response to organic substance GO:0071310 105 0.060
Worm
single organism cellular localization GO:1902580 46 0.060
small molecule catabolic process GO:0044282 3 0.060
reproductive process GO:0022414 40 0.059
regulation of cellular metabolic process GO:0031323 320 0.056
nucleocytoplasmic transport GO:0006913 4 0.056
Mouse
regulation of nucleoside metabolic process GO:0009118 2 0.056
establishment of localization in cell GO:0051649 77 0.055
Mouse
cellular localization GO:0051641 97 0.055
Mouse
cell part morphogenesis GO:0032990 246 0.054
macromolecular complex assembly GO:0065003 35 0.053
positive regulation of gene expression GO:0010628 71 0.053
oxidative phosphorylation GO:0006119 1 0.053
activation of innate immune response GO:0002218 6 0.052
intracellular estrogen receptor signaling pathway GO:0030520 3 0.052
organic acid metabolic process GO:0006082 31 0.052
positive regulation of biological process GO:0048518 253 0.052
positive regulation of cellular process GO:0048522 201 0.051
coenzyme biosynthetic process GO:0009108 2 0.051
cellular protein metabolic process GO:0044267 129 0.049
negative regulation of protein phosphorylation GO:0001933 4 0.049
macromolecular complex subunit organization GO:0043933 74 0.049
regulation of cell death GO:0010941 103 0.047
negative regulation of gene expression GO:0010629 65 0.047
positive regulation of biosynthetic process GO:0009891 68 0.045
multi organism process GO:0051704 134 0.045
nuclear export GO:0051168 1 0.045
Mouse
tissue regeneration GO:0042246 74 0.044
reproduction GO:0000003 40 0.043
Worm
regulation of cell communication GO:0010646 232 0.043
alpha amino acid metabolic process GO:1901605 3 0.043
single organism transport GO:0044765 206 0.043
Mouse
stem cell development GO:0048864 82 0.042
morphogenesis of an epithelium GO:0002009 333 0.042
regulation of response to stimulus GO:0048583 269 0.042
cellular amino acid metabolic process GO:0006520 7 0.040
protein import GO:0017038 3 0.039
carboxylic acid catabolic process GO:0046395 3 0.039
cellular response to oxygen levels GO:0071453 1 0.039
gene silencing by rna GO:0031047 4 0.039
negative regulation of biosynthetic process GO:0009890 55 0.038
developmental process involved in reproduction GO:0003006 27 0.037
regulation of proteolysis GO:0030162 24 0.037
mononuclear cell proliferation GO:0032943 1 0.037
negative regulation of macromolecule metabolic process GO:0010605 76 0.037
regulation of cellular amine metabolic process GO:0033238 0 0.037
phosphorus metabolic process GO:0006793 109 0.036
regulation of type i interferon production GO:0032479 2 0.036
regulation of developmental process GO:0050793 247 0.036
3 utr mediated mrna stabilization GO:0070935 3 0.036
cell proliferation GO:0008283 80 0.036
amine metabolic process GO:0009308 2 0.036
lipid storage GO:0019915 1 0.035
negative regulation of response to stimulus GO:0048585 104 0.035
regulation of cell activation GO:0050865 1 0.035
cellular ketone metabolic process GO:0042180 11 0.035
nucleoside phosphate biosynthetic process GO:1901293 21 0.034
organonitrogen compound metabolic process GO:1901564 74 0.034
regulation of multicellular organism growth GO:0040014 4 0.034
response to external biotic stimulus GO:0043207 97 0.033
cellular response to chemical stimulus GO:0070887 157 0.033
Worm
immune system process GO:0002376 241 0.033
regulation of biological quality GO:0065008 263 0.032
nucleoside monophosphate catabolic process GO:0009125 4 0.032
cell aging GO:0007569 2 0.032
regulation of signal transduction GO:0009966 225 0.032
regulation of purine nucleotide metabolic process GO:1900542 17 0.031
mesenchymal cell differentiation GO:0048762 87 0.031
maintenance of location GO:0051235 4 0.031
negative regulation of cell communication GO:0010648 96 0.031
positive regulation of apoptotic process GO:0043065 29 0.031
protein homooligomerization GO:0051260 3 0.030
toll like receptor signaling pathway GO:0002224 4 0.030
negative regulation of programmed cell death GO:0043069 58 0.030
negative regulation of cellular metabolic process GO:0031324 77 0.030
protein metabolic process GO:0019538 183 0.029
chordate embryonic development GO:0043009 271 0.029
regulation of signaling GO:0023051 235 0.029
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.029
regulation of circadian sleep wake cycle GO:0042749 1 0.029
cellular amine metabolic process GO:0044106 2 0.028
cellular macromolecular complex assembly GO:0034622 24 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
germ cell development GO:0007281 22 0.028
purine containing compound metabolic process GO:0072521 29 0.028
lymphocyte activation GO:0046649 10 0.028
protein localization GO:0008104 40 0.028
Mouse
negative regulation of protein kinase activity GO:0006469 4 0.027
regulation of catalytic activity GO:0050790 55 0.027
macromolecule localization GO:0033036 54 0.027
Mouse
vasculature development GO:0001944 278 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.027
protein stabilization GO:0050821 2 0.027
nucleoside triphosphate biosynthetic process GO:0009142 2 0.027
organic substance transport GO:0071702 58 0.027
Mouse
blood circulation GO:0008015 87 0.027
positive regulation of nucleic acid templated transcription GO:1903508 57 0.026
purine ribonucleoside biosynthetic process GO:0046129 2 0.026
positive regulation of proteolysis GO:0045862 10 0.026
lipid oxidation GO:0034440 1 0.026
purine nucleotide biosynthetic process GO:0006164 20 0.026
response to other organism GO:0051707 97 0.025
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
behavior GO:0007610 74 0.025
cofactor biosynthetic process GO:0051188 10 0.025
regulation of behavior GO:0050795 24 0.025
type i interferon production GO:0032606 2 0.024
blood vessel development GO:0001568 246 0.024
regulation of cell differentiation GO:0045595 142 0.024
rna export from nucleus GO:0006405 1 0.024
protein modification process GO:0036211 100 0.024
cellular protein complex assembly GO:0043623 19 0.024
response to amphetamine GO:0001975 1 0.023
positive regulation of macromolecule metabolic process GO:0010604 93 0.023
regulation of innate immune response GO:0045088 11 0.023
ribosomal small subunit biogenesis GO:0042274 2 0.023
organelle localization GO:0051640 49 0.023
negative regulation of kinase activity GO:0033673 4 0.023
positive regulation of transport GO:0051050 2 0.023
ribose phosphate metabolic process GO:0019693 27 0.023
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.023
positive regulation of catabolic process GO:0009896 4 0.022
heart development GO:0007507 313 0.022
regulation of molecular function GO:0065009 70 0.022
posttranscriptional gene silencing by rna GO:0035194 3 0.021
positive regulation of leukocyte mediated immunity GO:0002705 1 0.021
developmental growth GO:0048589 166 0.021
centrosome cycle GO:0007098 1 0.020
cellular macromolecule localization GO:0070727 21 0.020
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.020
purine nucleoside monophosphate catabolic process GO:0009128 4 0.020
cellular response to topologically incorrect protein GO:0035967 2 0.020
Worm
microtubule based process GO:0007017 60 0.020
negative regulation of cell death GO:0060548 60 0.020
ribonucleotide metabolic process GO:0009259 27 0.020
mesenchyme development GO:0060485 127 0.020
dna metabolic process GO:0006259 27 0.019
phosphorylation GO:0016310 69 0.019
transmembrane transport GO:0055085 120 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
neural crest cell differentiation GO:0014033 72 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
sensory organ development GO:0007423 393 0.019
positive regulation of cysteine type endopeptidase activity GO:2001056 10 0.019
negative regulation of rna biosynthetic process GO:1902679 45 0.019
rna transport GO:0050658 2 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.019
antimicrobial humoral response GO:0019730 2 0.018
circulatory system process GO:0003013 87 0.018
organic acid catabolic process GO:0016054 3 0.018
neurological system process GO:0050877 62 0.018
negative regulation of transcription dna templated GO:0045892 45 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.018
stem cell proliferation GO:0072089 4 0.018
dna biosynthetic process GO:0071897 3 0.018
regulation of blood vessel size GO:0050880 2 0.018
cell migration involved in heart development GO:0060973 22 0.018
immunoglobulin production GO:0002377 1 0.018
positive regulation of nucleotide catabolic process GO:0030813 1 0.018
fin regeneration GO:0031101 51 0.018
microtubule organizing center organization GO:0031023 1 0.018
blood vessel morphogenesis GO:0048514 216 0.018
histone deacetylation GO:0016575 2 0.017
phagocytosis GO:0006909 3 0.017
hepaticobiliary system development GO:0061008 98 0.017
connective tissue development GO:0061448 99 0.017
negative regulation of defense response GO:0031348 2 0.017
toxin transport GO:1901998 2 0.017
female gamete generation GO:0007292 14 0.017
negative regulation of apoptotic process GO:0043066 55 0.017
membrane repolarization GO:0086009 2 0.017
proteolysis GO:0006508 38 0.016
negative regulation of cellular biosynthetic process GO:0031327 55 0.016
atp catabolic process GO:0006200 4 0.016
brain development GO:0007420 293 0.016
purine ribonucleoside metabolic process GO:0046128 10 0.016
neural crest cell development GO:0014032 62 0.016
positive regulation of cellular biosynthetic process GO:0031328 68 0.016
regulation of cytokine production GO:0001817 3 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
positive regulation of immune system process GO:0002684 17 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 5 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
regulation of cellular component organization GO:0051128 86 0.016
regulation of hydrolase activity GO:0051336 28 0.015
single organism membrane organization GO:0044802 20 0.015
cellular response to endogenous stimulus GO:0071495 68 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
gamete generation GO:0007276 33 0.015
multicellular organismal reproductive process GO:0048609 35 0.015
b cell mediated immunity GO:0019724 3 0.015
reproductive system development GO:0061458 5 0.015
positive regulation of cell death GO:0010942 29 0.015
positive regulation of immune effector process GO:0002699 3 0.015
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
protein acetylation GO:0006473 2 0.015
macromolecule modification GO:0043412 111 0.015
positive regulation of molecular function GO:0044093 33 0.015
cytoplasmic transport GO:0016482 11 0.015
Mouse
head development GO:0060322 303 0.015
myeloid cell differentiation GO:0030099 86 0.015
cell morphogenesis GO:0000902 289 0.015
neuron death GO:0070997 21 0.015
nucleotide biosynthetic process GO:0009165 21 0.015
regulation of localization GO:0032879 104 0.015
gtp catabolic process GO:0006184 2 0.014
cellular protein localization GO:0034613 20 0.014
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 45 0.014
regulation of phosphate metabolic process GO:0019220 43 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
positive regulation of transcription dna templated GO:0045893 57 0.014
multicellular organism growth GO:0035264 4 0.014
circadian sleep wake cycle sleep GO:0050802 1 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
growth GO:0040007 174 0.014
positive regulation of programmed cell death GO:0043068 29 0.014
regulation of immune system process GO:0002682 34 0.014
immunoglobulin mediated immune response GO:0016064 3 0.013
negative regulation of signal transduction GO:0009968 94 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
axonal defasciculation GO:0007414 2 0.013
determination of heart left right asymmetry GO:0061371 117 0.013
regulation of lymphocyte mediated immunity GO:0002706 1 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
multicellular organism reproduction GO:0032504 35 0.013
regulation of gene expression epigenetic GO:0040029 11 0.013
nucleobase containing compound transport GO:0015931 2 0.013
posttranscriptional gene silencing GO:0016441 3 0.013
central nervous system development GO:0007417 387 0.013
cartilage development GO:0051216 96 0.013
branching morphogenesis of a nerve GO:0048755 4 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
nucleic acid transport GO:0050657 2 0.013
protein complex biogenesis GO:0070271 30 0.013
microtubule based movement GO:0007018 33 0.013
innate immune response activating signal transduction GO:0002758 5 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
mesenchymal cell development GO:0014031 78 0.012
negative regulation of signaling GO:0023057 96 0.012
taxis GO:0042330 109 0.012
digestive system development GO:0055123 289 0.012
cytoskeleton organization GO:0007010 96 0.012
response to stress GO:0006950 263 0.012
camera type eye development GO:0043010 222 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
tissue remodeling GO:0048771 4 0.012
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.012
inositol lipid mediated signaling GO:0048017 2 0.012
defense response to fungus GO:0050832 2 0.012
somatic cell dna recombination GO:0016444 1 0.012
female sex differentiation GO:0046660 4 0.012
cellular amino acid biosynthetic process GO:0008652 2 0.012
sulfur compound metabolic process GO:0006790 13 0.012
establishment of organelle localization GO:0051656 45 0.012
development of primary sexual characteristics GO:0045137 5 0.012
regulation of peptidase activity GO:0052547 23 0.012
intracellular signal transduction GO:0035556 85 0.012
regulation of lipid catabolic process GO:0050994 2 0.012
b cell proliferation GO:0042100 1 0.011
thioester metabolic process GO:0035383 1 0.011
axon development GO:0061564 166 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
positive regulation of cytokine production GO:0001819 2 0.011
forebrain development GO:0030900 96 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.011
neuron development GO:0048666 262 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
lymphocyte proliferation GO:0046651 1 0.011
ribonucleoside biosynthetic process GO:0042455 2 0.011
microtubule cytoskeleton organization GO:0000226 33 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
phagocytosis engulfment GO:0006911 1 0.011
regulation of nucleotide metabolic process GO:0006140 17 0.011
nucleotide metabolic process GO:0009117 28 0.011
protein deacylation GO:0035601 3 0.011
establishment of rna localization GO:0051236 3 0.011
nucleoside phosphate metabolic process GO:0006753 28 0.011
er nucleus signaling pathway GO:0006984 2 0.011
Worm
carbohydrate biosynthetic process GO:0016051 1 0.010
anatomical structure arrangement GO:0048532 2 0.010
organonitrogen compound biosynthetic process GO:1901566 47 0.010
response to endogenous stimulus GO:0009719 83 0.010
regulation of calcium ion transport GO:0051924 2 0.010
sensory perception of pain GO:0019233 1 0.010
internal protein amino acid acetylation GO:0006475 2 0.010
protein import into nucleus GO:0006606 3 0.010
negative regulation of heart contraction GO:0045822 2 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010
wound healing GO:0042060 90 0.010

hspa9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.448
sensory system disease DOID:0050155 0 0.360
eye and adnexa disease DOID:1492 0 0.360
nervous system disease DOID:863 0 0.360
eye disease DOID:5614 0 0.360
disease of cellular proliferation DOID:14566 0 0.080
cancer DOID:162 0 0.050
organ system cancer DOID:0050686 0 0.034
musculoskeletal system disease DOID:17 0 0.022
disease of metabolism DOID:0014667 0 0.020
breast cancer DOID:1612 0 0.018
thoracic cancer DOID:5093 0 0.018
inherited metabolic disorder DOID:655 0 0.018
mitochondrial metabolism disease DOID:700 0 0.013
amino acid metabolic disorder DOID:9252 0 0.012
neuromuscular disease DOID:440 0 0.011
charcot marie tooth disease DOID:10595 0 0.011
neuropathy DOID:870 0 0.011
heart disease DOID:114 0 0.010
cardiovascular system disease DOID:1287 0 0.010