Danio rerio

0 known processes

acin1a

apoptotic chromatin condensation inducer 1a

(Aliases: acinusa,wu:fb40f03,wu:fb68h03,wu:fb04g06,acinus,acinusl,wu:fb80f07,wu:fc12e10,xx:tdsubc_2g5,ik:tdsubc_2g5,si:zc14a17.12)

acin1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna splicing via spliceosome GO:0000398 10 0.204
Human
larval development GO:0002164 2 0.180
regulation of mrna splicing via spliceosome GO:0048024 3 0.145
Human
intracellular estrogen receptor signaling pathway GO:0030520 3 0.131
meiotic nuclear division GO:0007126 4 0.128
gene expression GO:0010467 252 0.118
Human
regulation of nucleocytoplasmic transport GO:0046822 2 0.115
nuclear import GO:0051170 3 0.110
locomotion GO:0040011 313 0.110
Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.101
Worm
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.099
immune system process GO:0002376 241 0.099
Human
regulation of meiotic cell cycle GO:0051445 1 0.096
alternative mrna splicing via spliceosome GO:0000380 1 0.089
regulation of metabolic process GO:0019222 359 0.084
Human
organic cyclic compound metabolic process GO:1901360 301 0.082
Human
protein targeting to nucleus GO:0044744 3 0.078
protein localization to nucleus GO:0034504 3 0.075
regulation of multicellular organism growth GO:0040014 4 0.073
cytokinesis GO:0000910 3 0.071
transport GO:0006810 220 0.068
cellular nitrogen compound metabolic process GO:0034641 290 0.065
Human
multicellular organism growth GO:0035264 4 0.063
regulation of mrna processing GO:0050684 3 0.061
Human
localization of cell GO:0051674 244 0.060
Worm
maintenance of location GO:0051235 4 0.059
hematopoietic or lymphoid organ development GO:0048534 191 0.059
Human
positive regulation of transport GO:0051050 2 0.058
establishment of protein localization to organelle GO:0072594 4 0.058
organelle organization GO:0006996 227 0.058
Human
neuroblast proliferation GO:0007405 2 0.057
negative regulation of ras protein signal transduction GO:0046580 1 0.056
nuclear transport GO:0051169 4 0.055
cellular biosynthetic process GO:0044249 286 0.054
stem cell proliferation GO:0072089 4 0.054
centrosome organization GO:0051297 1 0.053
cognition GO:0050890 1 0.053
regulation of protein targeting GO:1903533 2 0.049
protein import GO:0017038 3 0.048
regulation of protein catabolic process GO:0042176 1 0.047
single organism nuclear import GO:1902593 3 0.047
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.045
response to drug GO:0042493 3 0.045
stem cell division GO:0017145 1 0.045
regulation of cytoplasmic transport GO:1903649 4 0.044
cellular macromolecule metabolic process GO:0044260 391 0.043
Human
regulation of protein localization to nucleus GO:1900180 2 0.043
positive regulation of cell cycle GO:0045787 3 0.043
ubiquitin dependent protein catabolic process GO:0006511 3 0.043
regulation of establishment of protein localization GO:0070201 4 0.043
regulation of protein import into nucleus GO:0042306 2 0.042
neuron development GO:0048666 262 0.042
cellular component morphogenesis GO:0032989 336 0.042
positive regulation of cellular process GO:0048522 201 0.041
Human
positive regulation of biological process GO:0048518 253 0.041
Human
mitotic cell cycle GO:0000278 64 0.040
nucleocytoplasmic transport GO:0006913 4 0.039
response to uv GO:0009411 3 0.039
regulation of signal transduction GO:0009966 225 0.039
regulation of cellular biosynthetic process GO:0031326 245 0.038
regulation of signaling GO:0023051 235 0.038
gene silencing by rna GO:0031047 4 0.036
nitrogen compound metabolic process GO:0006807 319 0.036
Human
nucleic acid metabolic process GO:0090304 244 0.036
Human
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.036
cellular ketone metabolic process GO:0042180 11 0.035
immune system development GO:0002520 191 0.035
Human
regulation of cell differentiation GO:0045595 142 0.034
Human
aging GO:0007568 2 0.033
regulation of biosynthetic process GO:0009889 250 0.033
cellular component biogenesis GO:0044085 178 0.033
heterocycle metabolic process GO:0046483 290 0.033
Human
response to stress GO:0006950 263 0.033
regulation of intracellular protein transport GO:0033157 3 0.032
regulation of biological quality GO:0065008 263 0.032
Human
cellular aromatic compound metabolic process GO:0006725 295 0.032
Human
establishment of localization GO:0051234 244 0.031
regulation of protein transport GO:0051223 3 0.031
lipid storage GO:0019915 1 0.031
cell morphogenesis GO:0000902 289 0.030
modification dependent macromolecule catabolic process GO:0043632 3 0.030
regulation of cell activation GO:0050865 1 0.030
biosynthetic process GO:0009058 294 0.029
locomotor rhythm GO:0045475 3 0.029
negative regulation of developmental process GO:0051093 65 0.029
regulation of developmental process GO:0050793 247 0.029
Human
intracellular steroid hormone receptor signaling pathway GO:0030518 5 0.029
regulation of erk1 and erk2 cascade GO:0070372 4 0.028
single organism localization GO:1902578 225 0.028
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.028
Human
intracellular signal transduction GO:0035556 85 0.028
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.027
heterocycle biosynthetic process GO:0018130 215 0.027
mechanosensory behavior GO:0007638 2 0.027
cellular component movement GO:0006928 335 0.026
Worm
meiotic cell cycle process GO:1903046 3 0.026
signal transduction GO:0007165 455 0.026
neuron differentiation GO:0030182 353 0.025
regulation of gene expression GO:0010468 265 0.025
Human
regulation of cellular metabolic process GO:0031323 320 0.025
Human
cell motility GO:0048870 244 0.025
Worm
regulation of cell cycle GO:0051726 52 0.025
regulation of rna splicing GO:0043484 8 0.025
Human
organic cyclic compound biosynthetic process GO:1901362 223 0.024
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.024
generation of neurons GO:0048699 385 0.024
single organism organelle organization GO:1902589 199 0.024
Human
multicellular organism reproduction GO:0032504 35 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
negative regulation of metabolic process GO:0009892 86 0.023
Human
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.023
cell surface receptor signaling pathway GO:0007166 325 0.022
regulation of translational initiation GO:0006446 1 0.022
rna biosynthetic process GO:0032774 181 0.022
multi organism process GO:0051704 134 0.022
regulation of reproductive process GO:2000241 4 0.022
mesenchymal cell differentiation GO:0048762 87 0.022
erythrocyte homeostasis GO:0034101 55 0.021
Human
female gonad development GO:0008585 4 0.021
regulation of autophagy GO:0010506 3 0.021
regulation of cell shape GO:0008360 1 0.021
regulation of chromosome segregation GO:0051983 1 0.021
response to external stimulus GO:0009605 264 0.021
nucleic acid templated transcription GO:0097659 181 0.021
development of primary female sexual characteristics GO:0046545 4 0.021
mrna metabolic process GO:0016071 20 0.021
Human
macromolecular complex disassembly GO:0032984 1 0.021
sensory organ development GO:0007423 393 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
single organism transport GO:0044765 206 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.021
cellular response to extracellular stimulus GO:0031668 2 0.021
rna export from nucleus GO:0006405 1 0.020
mesenchyme development GO:0060485 127 0.020
intracellular receptor signaling pathway GO:0030522 30 0.020
amine metabolic process GO:0009308 2 0.020
rna transport GO:0050658 2 0.020
positive regulation of catabolic process GO:0009896 4 0.020
protein complex disassembly GO:0043241 1 0.020
rna metabolic process GO:0016070 219 0.020
Human
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
Human
growth GO:0040007 174 0.020
microtubule based process GO:0007017 60 0.020
hormone metabolic process GO:0042445 19 0.020
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.019
cytoskeleton organization GO:0007010 96 0.019
protein polymerization GO:0051258 4 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.019
cellular protein catabolic process GO:0044257 4 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
regulation of cytokine production GO:0001817 3 0.019
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.018
oocyte differentiation GO:0009994 14 0.018
positive regulation of metabolic process GO:0009893 108 0.018
negative regulation of synapse assembly GO:0051964 2 0.018
dna catabolic process GO:0006308 1 0.018
neuronal stem cell maintenance GO:0097150 2 0.018
regulation of macromolecule metabolic process GO:0060255 317 0.018
Human
organic substance biosynthetic process GO:1901576 289 0.017
nucleic acid transport GO:0050657 2 0.017
stem cell differentiation GO:0048863 117 0.017
aromatic compound biosynthetic process GO:0019438 217 0.017
negative regulation of cellular process GO:0048523 283 0.017
Human
regulation of primary metabolic process GO:0080090 311 0.017
Human
negative regulation of dna metabolic process GO:0051053 4 0.017
negative regulation of chromosome organization GO:2001251 1 0.017
epithelial cell differentiation GO:0030855 116 0.017
positive regulation of cell activation GO:0050867 1 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
system process GO:0003008 185 0.017
dna templated transcription elongation GO:0006354 3 0.017
protein import into nucleus GO:0006606 3 0.017
negative regulation of cell communication GO:0010648 96 0.017
organelle assembly GO:0070925 110 0.017
hemopoiesis GO:0030097 183 0.017
Human
nucleobase containing compound transport GO:0015931 2 0.017
antimicrobial humoral response GO:0019730 2 0.017
cellular response to starvation GO:0009267 1 0.017
response to external biotic stimulus GO:0043207 97 0.017
embryonic organ development GO:0048568 381 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
chordate embryonic development GO:0043009 271 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
phosphorus metabolic process GO:0006793 109 0.016
chemosensory behavior GO:0007635 1 0.016
regulation of synapse assembly GO:0051963 3 0.016
posttranscriptional gene silencing GO:0016441 3 0.016
cellular component assembly GO:0022607 170 0.016
nuclear export GO:0051168 1 0.016
regulation of response to stimulus GO:0048583 269 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
erk1 and erk2 cascade GO:0070371 4 0.015
negative regulation of biological process GO:0048519 304 0.015
Human
small molecule metabolic process GO:0044281 77 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
regulation of response to extracellular stimulus GO:0032104 1 0.015
cellular response to external stimulus GO:0071496 2 0.015
adult behavior GO:0030534 2 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
regulation of response to nutrient levels GO:0032107 1 0.015
positive regulation of gene expression GO:0010628 71 0.015
forebrain regionalization GO:0021871 4 0.015
mitotic dna integrity checkpoint GO:0044774 4 0.015
negative regulation of gliogenesis GO:0014014 1 0.015
spindle assembly GO:0051225 2 0.015
cell migration GO:0016477 237 0.015
Worm
negative regulation of nuclear division GO:0051784 3 0.015
negative regulation of gene expression GO:0010629 65 0.015
Human
p38mapk cascade GO:0038066 1 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
regulation of rna metabolic process GO:0051252 224 0.015
Human
positive regulation of leukocyte differentiation GO:1902107 1 0.015
Human
regulation of synapse organization GO:0050807 3 0.014
positive regulation of jnk cascade GO:0046330 3 0.014
regulation of protein complex assembly GO:0043254 3 0.014
cellular amine metabolic process GO:0044106 2 0.014
cell cycle GO:0007049 93 0.014
stem cell maintenance GO:0019827 4 0.014
meiotic spindle organization GO:0000212 1 0.014
diterpenoid metabolic process GO:0016101 15 0.014
sister chromatid cohesion GO:0007062 2 0.014
posttranscriptional gene silencing by rna GO:0035194 3 0.014
cellular component disassembly GO:0022411 1 0.014
Human
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
mitotic metaphase plate congression GO:0007080 1 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
response to biotic stimulus GO:0009607 97 0.014
axon guidance GO:0007411 86 0.014
centrosome cycle GO:0007098 1 0.014
negative regulation of defense response GO:0031348 2 0.014
establishment of rna localization GO:0051236 3 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
negative regulation of cytokine production GO:0001818 1 0.014
regulation of photoreceptor cell differentiation GO:0046532 2 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
translational initiation GO:0006413 3 0.014
single organism metabolic process GO:0044710 217 0.014
Human
female sex differentiation GO:0046660 4 0.013
cellular macromolecule biosynthetic process GO:0034645 224 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
rna localization GO:0006403 4 0.013
regulation of protein depolymerization GO:1901879 1 0.013
multi organism reproductive process GO:0044703 36 0.013
transcription dna templated GO:0006351 181 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
negative regulation of signal transduction GO:0009968 94 0.013
response to chemical GO:0042221 320 0.013
cell projection organization GO:0030030 284 0.013
cell projection morphogenesis GO:0048858 244 0.013
axon development GO:0061564 166 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
striated muscle cell differentiation GO:0051146 129 0.013
pigmentation GO:0043473 85 0.013
gene silencing GO:0016458 4 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
neuron projection guidance GO:0097485 86 0.013
neural crest cell differentiation GO:0014033 72 0.013
mitotic cell cycle process GO:1903047 48 0.013
regulation of transcription dna templated GO:0006355 213 0.013
ovulation cycle process GO:0022602 2 0.013
cell cycle process GO:0022402 53 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
muscle structure development GO:0061061 196 0.013
production of molecular mediator of immune response GO:0002440 2 0.012
stem cell development GO:0048864 82 0.012
regulation of neurological system process GO:0031644 2 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
regulation of protein complex disassembly GO:0043244 1 0.012
small gtpase mediated signal transduction GO:0007264 8 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
embryonic cranial skeleton morphogenesis GO:0048701 90 0.012
nucleobase containing compound metabolic process GO:0006139 274 0.012
Human
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.012
Human
g2 m transition of mitotic cell cycle GO:0000086 4 0.012
microtubule cytoskeleton organization GO:0000226 33 0.012
negative regulation of myeloid cell differentiation GO:0045638 1 0.012
primary neural tube formation GO:0014020 1 0.012
positive regulation of reproductive process GO:2000243 2 0.012
autophagy GO:0006914 4 0.012
g2 dna damage checkpoint GO:0031572 3 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.012
organic acid metabolic process GO:0006082 31 0.012
erythrocyte differentiation GO:0030218 54 0.012
Human
chromosome localization GO:0050000 2 0.012
response to oxygen radical GO:0000305 2 0.012
mesenchymal cell development GO:0014031 78 0.012
chromosome organization involved in meiosis GO:0070192 1 0.012
cell proliferation GO:0008283 80 0.012
oxoacid metabolic process GO:0043436 31 0.011
nuclear division GO:0000280 23 0.011
regulation of mrna metabolic process GO:1903311 6 0.011
Human
organism emergence from protective structure GO:0071684 4 0.011
muscle cell differentiation GO:0042692 139 0.011
macroautophagy GO:0016236 1 0.011
atp catabolic process GO:0006200 4 0.011
response to other organism GO:0051707 97 0.011
immunoglobulin production GO:0002377 1 0.011
cellular response to organic substance GO:0071310 105 0.011
negative regulation of multicellular organismal process GO:0051241 69 0.011
protein stabilization GO:0050821 2 0.011
mitotic cytokinesis GO:0000281 3 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
embryonic skeletal system morphogenesis GO:0048704 93 0.011
hatching GO:0035188 4 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
regulation of cell communication GO:0010646 232 0.011
spliceosomal complex assembly GO:0000245 1 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
mrna processing GO:0006397 14 0.010
Human
photoreceptor cell differentiation GO:0046530 55 0.010
positive regulation of dna metabolic process GO:0051054 1 0.010
camera type eye development GO:0043010 222 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
regulation of dna replication GO:0006275 3 0.010
digestive system development GO:0055123 289 0.010
regulation of response to cytokine stimulus GO:0060759 3 0.010
regulation of localization GO:0032879 104 0.010
Worm
response to carbohydrate GO:0009743 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
blood circulation GO:0008015 87 0.010
circulatory system process GO:0003013 87 0.010
positive regulation of dna templated transcription elongation GO:0032786 1 0.010
regulation of cell division GO:0051302 12 0.010
double strand break repair via homologous recombination GO:0000724 1 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
developmental growth GO:0048589 166 0.010
positive regulation of map kinase activity GO:0043406 3 0.010

acin1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.022
motor neuron disease DOID:231 0 0.018
central nervous system disease DOID:331 0 0.018
amyotrophic lateral sclerosis DOID:332 0 0.018
neurodegenerative disease DOID:1289 0 0.018
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.011