Danio rerio

0 known processes

im:7162646

im:7162646

im:7162646 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.665
cell projection organization GO:0030030 284 0.326
single organism transport GO:0044765 206 0.323
Worm
muscle cell differentiation GO:0042692 139 0.301
response to chemical GO:0042221 320 0.277
signal transduction GO:0007165 455 0.267
eye development GO:0001654 277 0.249
regulation of protein complex assembly GO:0043254 3 0.187
neuron development GO:0048666 262 0.174
cell surface receptor signaling pathway GO:0007166 325 0.172
positive regulation of protein complex assembly GO:0031334 2 0.167
positive regulation of cellular component biogenesis GO:0044089 3 0.161
regulation of developmental process GO:0050793 247 0.161
liver development GO:0001889 96 0.160
regionalization GO:0003002 274 0.154
establishment of localization GO:0051234 244 0.152
Worm
maintenance of location GO:0051235 4 0.143
single organism localization GO:1902578 225 0.141
Worm
cell morphogenesis GO:0000902 289 0.140
enzyme linked receptor protein signaling pathway GO:0007167 106 0.140
regulation of metabolic process GO:0019222 359 0.135
neuron projection development GO:0031175 180 0.134
regulation of signaling GO:0023051 235 0.126
Worm
segmentation GO:0035282 97 0.124
neuron projection morphogenesis GO:0048812 161 0.123
vasculature development GO:0001944 278 0.123
generation of neurons GO:0048699 385 0.119
camera type eye development GO:0043010 222 0.117
cell part morphogenesis GO:0032990 246 0.115
embryo development ending in birth or egg hatching GO:0009792 271 0.111
multicellular organism growth GO:0035264 4 0.105
eye morphogenesis GO:0048592 144 0.104
negative regulation of signal transduction GO:0009968 94 0.104
ear development GO:0043583 127 0.101
system process GO:0003008 185 0.098
axonogenesis GO:0007409 152 0.096
muscle structure development GO:0061061 196 0.095
cellular response to chemical stimulus GO:0070887 157 0.093
positive regulation of cellular process GO:0048522 201 0.093
optic placode formation GO:0001743 4 0.088
ion transport GO:0006811 114 0.087
Worm
negative regulation of response to stimulus GO:0048585 104 0.084
embryonic organ morphogenesis GO:0048562 274 0.084
larval development GO:0002164 2 0.084
lateral line development GO:0048882 66 0.081
cell projection morphogenesis GO:0048858 244 0.081
circulatory system process GO:0003013 87 0.079
camera type eye morphogenesis GO:0048593 108 0.077
regulation of multicellular organism growth GO:0040014 4 0.077
response to organic substance GO:0010033 153 0.074
cell migration GO:0016477 237 0.072
regulation of signal transduction GO:0009966 225 0.071
heart development GO:0007507 313 0.071
protein metabolic process GO:0019538 183 0.070
sensory organ morphogenesis GO:0090596 200 0.069
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.068
positive regulation of biological process GO:0048518 253 0.068
growth GO:0040007 174 0.067
neuron differentiation GO:0030182 353 0.067
embryonic camera type eye development GO:0031076 29 0.066
regulation of cellular metabolic process GO:0031323 320 0.065
embryonic organ development GO:0048568 381 0.065
sensory system development GO:0048880 76 0.065
cell motility GO:0048870 244 0.064
inner ear development GO:0048839 126 0.063
lateral line system development GO:0048925 76 0.062
negative regulation of signaling GO:0023057 96 0.062
posterior lateral line system development GO:0048915 46 0.061
gland development GO:0048732 143 0.059
regulation of cell differentiation GO:0045595 142 0.059
regulation of cell communication GO:0010646 232 0.057
Worm
regulation of apoptotic process GO:0042981 98 0.057
transport GO:0006810 220 0.057
Worm
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.056
regulation of cellular component size GO:0032535 30 0.055
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.055
cell morphogenesis involved in differentiation GO:0000904 195 0.054
positive regulation of muscle organ development GO:0048636 1 0.054
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.053
homeostatic process GO:0042592 142 0.051
positive regulation of cellular biosynthetic process GO:0031328 68 0.051
regulation of anatomical structure size GO:0090066 33 0.051
regulation of cell morphogenesis GO:0022604 42 0.050
locomotion GO:0040011 313 0.049
positive regulation of catalytic activity GO:0043085 25 0.048
cellular response to organic substance GO:0071310 105 0.048
striated muscle cell differentiation GO:0051146 129 0.047
determination of heart left right asymmetry GO:0061371 117 0.047
positive regulation of multicellular organismal process GO:0051240 52 0.046
fin development GO:0033333 77 0.045
hepaticobiliary system development GO:0061008 98 0.045
response to wounding GO:0009611 116 0.045
central nervous system development GO:0007417 387 0.044
blood circulation GO:0008015 87 0.044
kupffer s vesicle development GO:0070121 50 0.043
regulation of gtpase activity GO:0043087 2 0.043
gene expression GO:0010467 252 0.043
immune system process GO:0002376 241 0.042
muscle cell development GO:0055001 115 0.041
anterior posterior pattern specification GO:0009952 152 0.041
striated muscle cell development GO:0055002 108 0.041
localization of cell GO:0051674 244 0.041
developmental growth GO:0048589 166 0.040
apoptotic process GO:0006915 116 0.039
embryonic eye morphogenesis GO:0048048 30 0.039
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.039
blood vessel morphogenesis GO:0048514 216 0.039
regulation of axonogenesis GO:0050770 32 0.038
ion transmembrane transport GO:0034220 91 0.038
Worm
gall bladder development GO:0061010 1 0.038
lipid storage GO:0019915 1 0.038
muscle tissue development GO:0060537 110 0.037
post embryonic organ development GO:0048569 4 0.037
regulation of macromolecule metabolic process GO:0060255 317 0.036
epithelium regeneration GO:1990399 14 0.036
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.036
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.035
regulation of gtp catabolic process GO:0033124 2 0.035
axon extension GO:0048675 45 0.035
regulation of cell projection organization GO:0031344 44 0.035
axon development GO:0061564 166 0.035
cellular component morphogenesis GO:0032989 336 0.035
actin filament based process GO:0030029 64 0.035
cellular response to oxygen levels GO:0071453 1 0.034
cell death GO:0008219 121 0.034
response to stress GO:0006950 263 0.034
positive regulation of metabolic process GO:0009893 108 0.033
regulation of response to stimulus GO:0048583 269 0.033
regulation of primary metabolic process GO:0080090 311 0.033
cellular macromolecular complex assembly GO:0034622 24 0.032
negative regulation of cellular process GO:0048523 283 0.032
posterior lateral line development GO:0048916 38 0.032
kidney development GO:0001822 92 0.032
nitrogen compound metabolic process GO:0006807 319 0.031
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.031
spinal cord anterior posterior patterning GO:0021512 1 0.031
synaptic target recognition GO:0008039 1 0.030
stem cell proliferation GO:0072089 4 0.030
retina development in camera type eye GO:0060041 146 0.030
adherens junction assembly GO:0034333 1 0.030
cellular component movement GO:0006928 335 0.030
regulation of axon guidance GO:1902667 8 0.030
blood vessel development GO:0001568 246 0.029
fin morphogenesis GO:0033334 53 0.029
single organismal cell cell adhesion GO:0016337 29 0.029
regulation of macromolecule biosynthetic process GO:0010556 225 0.028
thrombocyte differentiation GO:0002574 4 0.028
regulation of localization GO:0032879 104 0.028
positive regulation of response to stimulus GO:0048584 80 0.028
somite development GO:0061053 96 0.028
ameboidal type cell migration GO:0001667 143 0.028
programmed cell death GO:0012501 119 0.028
nucleic acid templated transcription GO:0097659 181 0.027
convergent extension involved in gastrulation GO:0060027 71 0.027
embryonic heart tube development GO:0035050 133 0.027
chordate embryonic development GO:0043009 271 0.027
regulation of cell death GO:0010941 103 0.027
positive regulation of developmental process GO:0051094 50 0.026
regulation of anatomical structure morphogenesis GO:0022603 130 0.026
tube closure GO:0060606 1 0.025
brain development GO:0007420 293 0.025
positive regulation of protein polymerization GO:0032273 2 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.024
lymphocyte proliferation GO:0046651 1 0.024
regulation of neurological system process GO:0031644 2 0.024
regulation of axon extension GO:0030516 24 0.024
oocyte maturation GO:0001556 4 0.024
pectoral fin development GO:0033339 50 0.024
regulation of wnt signaling pathway GO:0030111 53 0.024
metal ion transport GO:0030001 58 0.024
Worm
mesoderm development GO:0007498 88 0.023
head development GO:0060322 303 0.023
cell fate commitment GO:0045165 99 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.023
epithelial tube morphogenesis GO:0060562 148 0.023
nucleobase containing compound biosynthetic process GO:0034654 205 0.023
regulation of stem cell differentiation GO:2000736 4 0.023
response to endogenous stimulus GO:0009719 83 0.023
developmental cell growth GO:0048588 52 0.023
multicellular organism reproduction GO:0032504 35 0.023
positive regulation of cell cycle GO:0045787 3 0.022
regulation of protein polymerization GO:0032271 2 0.022
hepatocyte proliferation GO:0072574 2 0.022
regulation of nervous system development GO:0051960 90 0.022
positive regulation of catabolic process GO:0009896 4 0.022
hematopoietic or lymphoid organ development GO:0048534 191 0.022
mononuclear cell proliferation GO:0032943 1 0.022
inner ear morphogenesis GO:0042472 63 0.022
optic placode formation involved in camera type eye formation GO:0046619 3 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
rna metabolic process GO:0016070 219 0.021
somitogenesis GO:0001756 87 0.021
skeletal system development GO:0001501 181 0.021
cellular response to hypoxia GO:0071456 1 0.021
heart morphogenesis GO:0003007 156 0.021
axon guidance GO:0007411 86 0.021
regulation of cell activation GO:0050865 1 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
cell recognition GO:0008037 19 0.021
epithelial cell differentiation GO:0030855 116 0.021
determination of bilateral symmetry GO:0009855 204 0.020
neuron projection extension GO:1990138 45 0.020
urogenital system development GO:0001655 97 0.020
aging GO:0007568 2 0.020
immune system development GO:0002520 191 0.020
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.020
skin development GO:0043588 54 0.020
actin cytoskeleton organization GO:0030036 63 0.020
transcription from rna polymerase ii promoter GO:0006366 80 0.020
otolith development GO:0048840 32 0.020
regulation of anterior head development GO:2000742 2 0.020
compound eye development GO:0048749 2 0.020
regulation of cell size GO:0008361 29 0.020
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.020
regulation of multicellular organismal process GO:0051239 277 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
regulation of neurogenesis GO:0050767 87 0.019
cellular response to endogenous stimulus GO:0071495 68 0.019
angiogenesis GO:0001525 158 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
skeletal system morphogenesis GO:0048705 102 0.019
positive regulation of macromolecule metabolic process GO:0010604 93 0.018
regulation of embryonic development GO:0045995 47 0.018
leukocyte proliferation GO:0070661 1 0.018
fibril organization GO:0097435 1 0.018
positive regulation of cytoskeleton organization GO:0051495 3 0.018
regulation of circadian sleep wake cycle GO:0042749 1 0.018
protein localization to nucleus GO:0034504 3 0.018
specification of symmetry GO:0009799 204 0.018
regulation of system process GO:0044057 40 0.018
homeostasis of number of cells GO:0048872 62 0.018
regulation of nucleotide catabolic process GO:0030811 2 0.018
gtp metabolic process GO:0046039 4 0.018
single organism reproductive process GO:0044702 40 0.018
diencephalon development GO:0021536 58 0.018
positive regulation of rna metabolic process GO:0051254 59 0.018
regulation of vasculature development GO:1901342 33 0.017
regulation of growth GO:0040008 42 0.017
regulation of extent of cell growth GO:0061387 29 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
positive regulation of cellular metabolic process GO:0031325 94 0.017
forebrain regionalization GO:0021871 4 0.017
positive regulation of map kinase activity GO:0043406 3 0.017
rna biosynthetic process GO:0032774 181 0.017
appendage development GO:0048736 80 0.017
palate development GO:0060021 8 0.016
positive regulation of transport GO:0051050 2 0.016
cellular response to nutrient levels GO:0031669 2 0.016
common bile duct development GO:0061009 13 0.016
adenohypophysis development GO:0021984 15 0.016
cellular macromolecule metabolic process GO:0044260 391 0.016
cellular response to hormone stimulus GO:0032870 39 0.016
negative regulation of epithelial cell proliferation GO:0050680 1 0.016
epidermis development GO:0008544 48 0.016
response to abiotic stimulus GO:0009628 122 0.016
convergent extension GO:0060026 118 0.016
response to external stimulus GO:0009605 264 0.016
cellular nitrogen compound metabolic process GO:0034641 290 0.016
embryonic hemopoiesis GO:0035162 53 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
midbrain development GO:0030901 28 0.015
cell cell signaling GO:0007267 52 0.015
Worm
cellular response to growth factor stimulus GO:0071363 39 0.015
digestive tract morphogenesis GO:0048546 231 0.015
cell proliferation GO:0008283 80 0.015
neuron projection guidance GO:0097485 86 0.015
primary neural tube formation GO:0014020 1 0.015
embryonic appendage morphogenesis GO:0035113 30 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.015
regulation of neuron projection development GO:0010975 40 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
membrane fusion GO:0061025 2 0.015
regeneration GO:0031099 91 0.015
cellular aromatic compound metabolic process GO:0006725 295 0.015
endocrine system development GO:0035270 65 0.014
negative regulation of cell communication GO:0010648 96 0.014
mechanosensory lateral line system development GO:0048881 49 0.014
heterocycle metabolic process GO:0046483 290 0.014
regulation of biological quality GO:0065008 263 0.014
tissue regeneration GO:0042246 74 0.014
regulation of transcription dna templated GO:0006355 213 0.014
regulation of molecular function GO:0065009 70 0.014
cellular protein complex assembly GO:0043623 19 0.014
regulation of cellular component movement GO:0051270 55 0.014
mediolateral intercalation GO:0060031 3 0.014
small molecule metabolic process GO:0044281 77 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
embryonic skeletal system development GO:0048706 97 0.014
facial nerve development GO:0021561 3 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
neurological system process GO:0050877 62 0.014
cellular response to external stimulus GO:0071496 2 0.014
mesenchymal cell proliferation GO:0010463 1 0.014
cellular response to decreased oxygen levels GO:0036294 1 0.014
death GO:0016265 121 0.014
activation of mapk activity GO:0000187 3 0.014
regulation of cellular component organization GO:0051128 86 0.014
positive regulation of biosynthetic process GO:0009891 68 0.014
determination of left right symmetry GO:0007368 179 0.013
cell cell recognition GO:0009988 1 0.013
embryonic skeletal joint development GO:0072498 3 0.013
hindbrain development GO:0030902 91 0.013
fin regeneration GO:0031101 51 0.013
regulation of organ growth GO:0046620 3 0.013
regulation of blood pressure GO:0008217 1 0.013
non canonical wnt signaling pathway GO:0035567 13 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
regulation of cellular response to drug GO:2001038 1 0.013
regulation of cell migration GO:0030334 40 0.013
cellular nitrogen compound biosynthetic process GO:0044271 218 0.013
heart process GO:0003015 71 0.013
axon extension involved in axon guidance GO:0048846 10 0.013
wound healing GO:0042060 90 0.013
negative regulation of cell death GO:0060548 60 0.013
smooth muscle contraction GO:0006939 2 0.013
regulation of locomotion GO:0040012 55 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
regulation of catalytic activity GO:0050790 55 0.013
response to hormone GO:0009725 48 0.012
pigmentation GO:0043473 85 0.012
mesodermal cell differentiation GO:0048333 21 0.012
chemotaxis GO:0006935 104 0.012
gtp catabolic process GO:0006184 2 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
taxis GO:0042330 109 0.012
circadian sleep wake cycle GO:0042745 2 0.012
otic placode formation GO:0043049 23 0.012
cell cell signaling involved in cell fate commitment GO:0045168 12 0.012
anterior head development GO:0097065 2 0.012
digestive system development GO:0055123 289 0.012
reproduction GO:0000003 40 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
organelle organization GO:0006996 227 0.012
organic cyclic compound metabolic process GO:1901360 301 0.012
tube morphogenesis GO:0035239 349 0.012
forebrain development GO:0030900 96 0.012
regulation of hydrolase activity GO:0051336 28 0.012
regulation of dna replication GO:0006275 3 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
cell fate specification GO:0001708 68 0.011
sensory perception of pain GO:0019233 1 0.011
positive regulation of locomotion GO:0040017 14 0.011
wnt signaling pathway GO:0016055 80 0.011
multi organism process GO:0051704 134 0.011
actin filament polymerization GO:0030041 2 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
positive regulation of cell division GO:0051781 2 0.011
release of sequestered calcium ion into cytosol GO:0051209 3 0.011
single organism organelle organization GO:1902589 199 0.011
response to external biotic stimulus GO:0043207 97 0.011
protein polymerization GO:0051258 4 0.011
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.011
morphogenesis of embryonic epithelium GO:0016331 30 0.010
neuroblast proliferation GO:0007405 2 0.010
astrocyte differentiation GO:0048708 1 0.010
swim bladder development GO:0048794 19 0.010
embryonic camera type eye morphogenesis GO:0048596 19 0.010
cellular component biogenesis GO:0044085 178 0.010
cation transport GO:0006812 81 0.010
Worm
pectoral fin morphogenesis GO:0035138 29 0.010
circadian sleep wake cycle sleep GO:0050802 1 0.010
skeletal muscle tissue development GO:0007519 67 0.010

im:7162646 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.021
bone development disease DOID:0080006 0 0.021
musculoskeletal system disease DOID:17 0 0.021
bone disease DOID:0080001 0 0.021
dysostosis DOID:1934 0 0.021
connective tissue disease DOID:65 0 0.021
synostosis DOID:11971 0 0.021
developmental disorder of mental health DOID:0060037 0 0.014
disease of mental health DOID:150 0 0.014
physical disorder DOID:0080015 0 0.012
orofacial cleft DOID:0050567 0 0.012
acrocephalosyndactylia DOID:12960 0 0.011
pfeiffer syndrome DOID:14705 0 0.011