Danio rerio

0 known processes

hsp90a.2

heat shock protein 90-alpha 2

(Aliases: hsp90a2,cb820)

hsp90a.2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule metabolic process GO:0044260 391 0.676
Worm
larval development GO:0002164 2 0.654
Worm
regulation of metabolic process GO:0019222 359 0.562
Human Mouse
negative regulation of biological process GO:0048519 304 0.555
Fly
response to abiotic stimulus GO:0009628 122 0.519
Rat Fly
organophosphate metabolic process GO:0019637 37 0.498
Human Worm
locomotion GO:0040011 313 0.492
Rat Worm
nitrogen compound metabolic process GO:0006807 319 0.456
Human Mouse Worm
response to stress GO:0006950 263 0.428
Rat Worm Fly
positive regulation of catabolic process GO:0009896 4 0.423
cellular component morphogenesis GO:0032989 336 0.401
Zebrafish Fly
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.401
Human Worm
mitochondrion organization GO:0007005 4 0.399
Human
response to temperature stimulus GO:0009266 15 0.387
Rat Fly
ribonucleoside monophosphate catabolic process GO:0009158 4 0.385
Human Worm
response to heat GO:0009408 6 0.383
Rat Fly
response to cadmium ion GO:0046686 14 0.372
purine nucleoside monophosphate catabolic process GO:0009128 4 0.367
Human Worm
purine nucleotide metabolic process GO:0006163 27 0.356
Human Worm
regulation of binding GO:0051098 3 0.339
atp catabolic process GO:0006200 4 0.337
Human Worm
gene expression GO:0010467 252 0.336
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.329
organic cyclic compound metabolic process GO:1901360 301 0.326
Human Worm
negative regulation of protein kinase activity GO:0006469 4 0.313
cellular nitrogen compound metabolic process GO:0034641 290 0.296
Human Mouse Worm
ribose phosphate metabolic process GO:0019693 27 0.288
Human Worm
regulation of nitrogen compound metabolic process GO:0051171 251 0.285
Mouse
regulation of nucleoside metabolic process GO:0009118 2 0.283
cellular aromatic compound metabolic process GO:0006725 295 0.282
Human Worm
ribonucleotide metabolic process GO:0009259 27 0.260
Human Worm
positive regulation of nucleoside metabolic process GO:0045979 1 0.259
system process GO:0003008 185 0.247
Rat
small molecule metabolic process GO:0044281 77 0.243
Human Worm
death GO:0016265 121 0.240
Rat Worm
positive regulation of nucleotide catabolic process GO:0030813 1 0.234
negative regulation of protein phosphorylation GO:0001933 4 0.232
cellular response to topologically incorrect protein GO:0035967 2 0.230
heterocycle metabolic process GO:0046483 290 0.224
Human Worm
response to chemical GO:0042221 320 0.217
Rat
cellular biosynthetic process GO:0044249 286 0.210
Mouse
nucleoside monophosphate catabolic process GO:0009125 4 0.210
Human Worm
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.208
response to organic substance GO:0010033 153 0.206
Rat
positive regulation of biological process GO:0048518 253 0.191
Mouse Rat
regulation of primary metabolic process GO:0080090 311 0.181
regulation of cellular component organization GO:0051128 86 0.181
Rat Fly
establishment of localization GO:0051234 244 0.180
Human Rat
cellular component assembly GO:0022607 170 0.167
Human Zebrafish Rat Fly
cellular aldehyde metabolic process GO:0006081 4 0.167
signal transduction GO:0007165 455 0.155
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.154
cellular protein metabolic process GO:0044267 129 0.153
Worm
protein stabilization GO:0050821 2 0.153
regulation of cellular metabolic process GO:0031323 320 0.149
Mouse
macromolecular complex subunit organization GO:0043933 74 0.148
Human Zebrafish Fly
cellular component movement GO:0006928 335 0.147
Rat
regulation of gene expression GO:0010468 265 0.143
regulation of nucleotide catabolic process GO:0030811 2 0.142
phosphate containing compound metabolic process GO:0006796 108 0.141
Human Worm
response to metal ion GO:0010038 34 0.140
biosynthetic process GO:0009058 294 0.139
Mouse
pyruvate metabolic process GO:0006090 1 0.137
organic substance biosynthetic process GO:1901576 289 0.133
positive regulation of cellular catabolic process GO:0031331 3 0.132
regulation of developmental process GO:0050793 247 0.132
Fly
purine ribonucleotide metabolic process GO:0009150 27 0.128
Human Worm
regulation of biological quality GO:0065008 263 0.128
Rat Fly
regulation of protein binding GO:0043393 3 0.127
catabolic process GO:0009056 32 0.126
Human Worm
regulation of macromolecule metabolic process GO:0060255 317 0.126
nucleocytoplasmic transport GO:0006913 4 0.126
Rat
single organism biosynthetic process GO:0044711 71 0.125
transport GO:0006810 220 0.119
Human Rat
negative regulation of cellular metabolic process GO:0031324 77 0.119
regulation of purine nucleotide catabolic process GO:0033121 2 0.118
single organism organelle organization GO:1902589 199 0.117
Human Zebrafish Fly
protein complex biogenesis GO:0070271 30 0.115
Human Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.115
Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.114
respiratory electron transport chain GO:0022904 2 0.112
regulation of metal ion transport GO:0010959 4 0.112
negative regulation of cellular process GO:0048523 283 0.110
Fly
cellular response to stress GO:0033554 62 0.109
macromolecular complex assembly GO:0065003 35 0.108
Human Zebrafish
centrosome organization GO:0051297 1 0.106
Fly
positive regulation of multicellular organismal process GO:0051240 52 0.106
Rat
response to external stimulus GO:0009605 264 0.106
membrane repolarization GO:0086009 2 0.105
nucleoside monophosphate metabolic process GO:0009123 6 0.104
Human Worm
programmed cell death GO:0012501 119 0.103
Rat Worm
phosphorus metabolic process GO:0006793 109 0.103
Human Worm
regulation of response to stimulus GO:0048583 269 0.102
Fly
regulation of cell death GO:0010941 103 0.102
purine ribonucleoside monophosphate metabolic process GO:0009167 5 0.102
Human Worm
protein metabolic process GO:0019538 183 0.100
Worm
regulation of nucleotide metabolic process GO:0006140 17 0.099
protein localization to membrane GO:0072657 9 0.097
Human
synaptic growth at neuromuscular junction GO:0051124 2 0.097
nucleoside phosphate metabolic process GO:0006753 28 0.096
Human Worm
single organism localization GO:1902578 225 0.096
Human Rat Fly
aging GO:0007568 2 0.092
Worm
cellular macromolecule biosynthetic process GO:0034645 224 0.092
protein polymerization GO:0051258 4 0.091
organonitrogen compound metabolic process GO:1901564 74 0.090
Human Worm
nucleotide metabolic process GO:0009117 28 0.090
Human Worm
cellular protein complex assembly GO:0043623 19 0.090
Human Zebrafish
cellular localization GO:0051641 97 0.090
Human Rat Fly
regulation of hydrolase activity GO:0051336 28 0.089
regulation of molecular function GO:0065009 70 0.089
Human Mouse
microtubule organizing center organization GO:0031023 1 0.089
Fly
positive regulation of cellular process GO:0048522 201 0.087
Mouse Rat
regulation of rna metabolic process GO:0051252 224 0.084
adult behavior GO:0030534 2 0.084
cellular component biogenesis GO:0044085 178 0.083
Human Zebrafish Rat Fly
single organism metabolic process GO:0044710 217 0.083
Human Mouse Worm
multicellular organism growth GO:0035264 4 0.082
response to unfolded protein GO:0006986 2 0.082
maintenance of location GO:0051235 4 0.081
regulation of localization GO:0032879 104 0.081
Rat
negative regulation of kinase activity GO:0033673 4 0.080
single organism transport GO:0044765 206 0.079
Human Rat
response to topologically incorrect protein GO:0035966 2 0.078
purine ribonucleoside metabolic process GO:0046128 10 0.078
Human Worm
positive regulation of cell death GO:0010942 29 0.077
regulation of purine nucleotide metabolic process GO:1900542 17 0.076
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.073
aromatic compound biosynthetic process GO:0019438 217 0.073
regulation of multicellular organismal development GO:2000026 223 0.073
protein localization to nucleus GO:0034504 3 0.073
Rat
regionalization GO:0003002 274 0.072
Fly
regulation of phosphorus metabolic process GO:0051174 43 0.072
carbohydrate derivative metabolic process GO:1901135 61 0.070
Human Worm
endoplasmic reticulum unfolded protein response GO:0030968 2 0.069
organic cyclic compound biosynthetic process GO:1901362 223 0.068
vasculature development GO:0001944 278 0.068
Zebrafish
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.068
generation of neurons GO:0048699 385 0.067
Rat
regulation of rna biosynthetic process GO:2001141 213 0.066
organelle organization GO:0006996 227 0.065
Human Zebrafish Fly
protein complex assembly GO:0006461 30 0.064
Human Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.064
Rat Fly
blood vessel development GO:0001568 246 0.063
Zebrafish
heart development GO:0007507 313 0.063
regulation of multicellular organism growth GO:0040014 4 0.062
cellular sodium ion homeostasis GO:0006883 1 0.061
positive regulation of molecular function GO:0044093 33 0.060
regulation of protein complex assembly GO:0043254 3 0.060
cell surface receptor signaling pathway GO:0007166 325 0.059
regulation of protein polymerization GO:0032271 2 0.059
atp metabolic process GO:0046034 5 0.059
Human Worm
regulation of apoptotic process GO:0042981 98 0.059
protein import GO:0017038 3 0.058
Human Rat
rna localization GO:0006403 4 0.058
Fly
heart contraction GO:0060047 71 0.056
Rat
gtp metabolic process GO:0046039 4 0.056
cellular response to chemical stimulus GO:0070887 157 0.056
cellular component disassembly GO:0022411 1 0.056
nucleoside metabolic process GO:0009116 11 0.056
Human Worm
cellular nitrogen compound biosynthetic process GO:0044271 218 0.056
Mouse
glycosyl compound metabolic process GO:1901657 11 0.055
Human Worm
organic substance transport GO:0071702 58 0.055
Human Rat
oxoacid metabolic process GO:0043436 31 0.054
cellular potassium ion transport GO:0071804 10 0.054
macromolecule localization GO:0033036 54 0.054
Human Rat Fly
protein localization to plasma membrane GO:0072659 1 0.053
neurological system process GO:0050877 62 0.053
heterocycle biosynthetic process GO:0018130 215 0.053
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.053
membrane hyperpolarization GO:0060081 1 0.053
actin polymerization or depolymerization GO:0008154 2 0.052
nucleobase containing small molecule metabolic process GO:0055086 32 0.052
Human Worm
response to inorganic substance GO:0010035 38 0.051
amine metabolic process GO:0009308 2 0.051
regulation of biosynthetic process GO:0009889 250 0.051
Mouse
negative regulation of metabolic process GO:0009892 86 0.051
rna biosynthetic process GO:0032774 181 0.050
cellular macromolecule localization GO:0070727 21 0.050
Human Rat Fly
neuron differentiation GO:0030182 353 0.050
neuron development GO:0048666 262 0.049
modification dependent macromolecule catabolic process GO:0043632 3 0.049
protein complex disassembly GO:0043241 1 0.048
negative regulation of cellular component organization GO:0051129 16 0.048
carboxylic acid metabolic process GO:0019752 22 0.048
protein localization GO:0008104 40 0.047
Human Rat
cellular amine metabolic process GO:0044106 2 0.047
cellular modified amino acid metabolic process GO:0006575 3 0.046
cell part morphogenesis GO:0032990 246 0.046
transmembrane transport GO:0055085 120 0.046
Human
positive regulation of type i interferon production GO:0032481 1 0.046
organic acid metabolic process GO:0006082 31 0.045
positive regulation of cellular metabolic process GO:0031325 94 0.045
Mouse
protein complex subunit organization GO:0071822 46 0.045
Human Zebrafish Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.045
heart process GO:0003015 71 0.044
Rat
cell cycle GO:0007049 93 0.044
Fly
electron transport chain GO:0022900 2 0.043
single organism membrane organization GO:0044802 20 0.043
Human
regulation of phosphate metabolic process GO:0019220 43 0.042
positive regulation of metabolic process GO:0009893 108 0.042
Mouse
meiotic nuclear division GO:0007126 4 0.042
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.042
ribonucleoside metabolic process GO:0009119 11 0.042
Human Worm
intracellular transport GO:0046907 32 0.041
Human Rat
cellular response to radiation GO:0071478 4 0.041
actin filament polymerization GO:0030041 2 0.040
regulation of dna replication GO:0006275 3 0.039
single organism intracellular transport GO:1902582 25 0.039
Human Rat
ventricular cardiac muscle tissue development GO:0003229 3 0.039
single organism cellular localization GO:1902580 46 0.039
Human Rat Fly
positive regulation of transport GO:0051050 2 0.039
Rat
actin filament based process GO:0030029 64 0.038
Zebrafish Fly
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.038
oxidation reduction process GO:0055114 41 0.038
Human Mouse
protein import into nucleus GO:0006606 3 0.038
Rat
cellular response to starvation GO:0009267 1 0.037
actin filament based movement GO:0030048 1 0.037
regulation of protein ubiquitination GO:0031396 3 0.037
muscle cell development GO:0055001 115 0.036
Zebrafish
sensory organ development GO:0007423 393 0.036
blood circulation GO:0008015 87 0.035
Rat
gamete generation GO:0007276 33 0.035
Fly
cytoskeleton organization GO:0007010 96 0.035
Zebrafish Fly
cytokinetic process GO:0032506 2 0.035
oocyte anterior posterior axis specification GO:0007314 4 0.034
Fly
organic substance catabolic process GO:1901575 28 0.034
Human Worm
multi organism process GO:0051704 134 0.034
Fly
guanosine containing compound catabolic process GO:1901069 2 0.034
ion transmembrane transport GO:0034220 91 0.033
startle response GO:0001964 4 0.033
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.033
regulation of protein depolymerization GO:1901879 1 0.033
regulation of muscle contraction GO:0006937 3 0.032
Rat
maternal determination of anterior posterior axis embryo GO:0008358 4 0.032
Fly
macromolecule biosynthetic process GO:0009059 227 0.032
microtubule based process GO:0007017 60 0.032
Fly
positive regulation of jnk cascade GO:0046330 3 0.032
gtp catabolic process GO:0006184 2 0.032
regulation of cellular amino acid metabolic process GO:0006521 0 0.032
cell cell recognition GO:0009988 1 0.032
blood vessel morphogenesis GO:0048514 216 0.031
positive regulation of nucleotide metabolic process GO:0045981 9 0.031
regulation of signaling GO:0023051 235 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
single organism nuclear import GO:1902593 3 0.031
Rat
regulation of dna templated transcription in response to stress GO:0043620 0 0.031
negative regulation of mapk cascade GO:0043409 4 0.030
lipid storage GO:0019915 1 0.030
immune system development GO:0002520 191 0.030
response to antibiotic GO:0046677 1 0.030
ubiquitin dependent protein catabolic process GO:0006511 3 0.030
spermatid development GO:0007286 2 0.029
mitochondrial transport GO:0006839 2 0.029
Human
regulation of gtp catabolic process GO:0033124 2 0.029
regeneration GO:0031099 91 0.029
negative regulation of protein metabolic process GO:0051248 16 0.028
anterior posterior pattern specification GO:0009952 152 0.028
Fly
lamellipodium organization GO:0097581 1 0.028
Rat
developmental growth GO:0048589 166 0.028
positive regulation of developmental process GO:0051094 50 0.028
cytoplasm organization GO:0007028 4 0.028
Fly
macromolecule modification GO:0043412 111 0.028
Worm
transcription from rna polymerase ii promoter GO:0006366 80 0.027
purine containing compound metabolic process GO:0072521 29 0.027
Human Worm
cellular response to extracellular stimulus GO:0031668 2 0.027
positive regulation of cellular component biogenesis GO:0044089 3 0.027
Rat
regulation of programmed cell death GO:0043067 101 0.027
nuclear export GO:0051168 1 0.027
muscle structure development GO:0061061 196 0.027
Zebrafish
transcription dna templated GO:0006351 181 0.027
locomotor rhythm GO:0045475 3 0.027
eye development GO:0001654 277 0.027
spermatid differentiation GO:0048515 2 0.026
regulation of macromolecule biosynthetic process GO:0010556 225 0.026
negative regulation of apoptotic process GO:0043066 55 0.026
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.026
protein phosphorylation GO:0006468 47 0.026
Worm
leukocyte proliferation GO:0070661 1 0.025
cellular macromolecular complex assembly GO:0034622 24 0.025
Human Zebrafish
positive regulation of hydrolase activity GO:0051345 13 0.025
nucleobase containing compound catabolic process GO:0034655 15 0.025
Human Worm
regulation of synapse assembly GO:0051963 3 0.025
phagocytosis GO:0006909 3 0.025
nucleic acid templated transcription GO:0097659 181 0.025
organelle assembly GO:0070925 110 0.024
Zebrafish
nucleoside biosynthetic process GO:0009163 2 0.024
regulation of transport GO:0051049 45 0.024
Rat
cell cycle arrest GO:0007050 1 0.024
regulation of cytokine production GO:0001817 3 0.024
regulation of protein transport GO:0051223 3 0.024
Rat
skeletal system development GO:0001501 181 0.024
centrosome cycle GO:0007098 1 0.024
Fly
actomyosin structure organization GO:0031032 53 0.024
Zebrafish
protein depolymerization GO:0051261 1 0.024
cytokinesis GO:0000910 3 0.024
reproduction GO:0000003 40 0.024
Worm Fly
cellular response to unfolded protein GO:0034620 2 0.023
skeletal muscle tissue development GO:0007519 67 0.023
epithelial cell morphogenesis GO:0003382 2 0.023
negative regulation of map kinase activity GO:0043407 2 0.023
cell cycle g1 s phase transition GO:0044843 1 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.023
nucleoside catabolic process GO:0009164 7 0.023
Human Worm
cell morphogenesis GO:0000902 289 0.023
Fly
cell projection assembly GO:0030031 64 0.023
Rat
muscle contraction GO:0006936 18 0.023
Rat
single organism reproductive process GO:0044702 40 0.023
Worm Fly
b cell differentiation GO:0030183 1 0.023
central nervous system development GO:0007417 387 0.022
establishment of protein localization to organelle GO:0072594 4 0.022
Human Rat
detection of stimulus GO:0051606 29 0.022
purine containing compound biosynthetic process GO:0072522 20 0.022
head development GO:0060322 303 0.022
regulation of transmembrane transporter activity GO:0022898 2 0.022
regulation of membrane potential GO:0042391 23 0.022
single fertilization GO:0007338 3 0.022
cilium morphogenesis GO:0060271 85 0.022
regulation of cell shape GO:0008360 1 0.022
Fly
regulation of reproductive process GO:2000241 4 0.022
digestive tract development GO:0048565 265 0.022
mitotic dna damage checkpoint GO:0044773 4 0.022
rna metabolic process GO:0016070 219 0.021
regulation of transporter activity GO:0032409 2 0.021
lateral inhibition GO:0046331 1 0.021
cell motility GO:0048870 244 0.021
Rat
determination of bilateral symmetry GO:0009855 204 0.021
cellular protein catabolic process GO:0044257 4 0.021
protein acetylation GO:0006473 2 0.021
embryonic organ development GO:0048568 381 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
Rat
growth GO:0040007 174 0.021
regulation of gtpase activity GO:0043087 2 0.021
negative regulation of cellular protein metabolic process GO:0032269 16 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 6 0.021
Human Worm
regulation of cellular component biogenesis GO:0044087 12 0.021
Rat
regulation of nucleocytoplasmic transport GO:0046822 2 0.021
Rat
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.020
fertilization GO:0009566 3 0.020
nucleic acid transport GO:0050657 2 0.020
regulation of organelle organization GO:0033043 29 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
hepaticobiliary system development GO:0061008 98 0.020
cellular carbohydrate metabolic process GO:0044262 4 0.020
regulation of reactive oxygen species metabolic process GO:2000377 2 0.020
cellular protein modification process GO:0006464 100 0.020
Worm
regulation of calcium ion transport GO:0051924 2 0.020
b cell activation GO:0042113 2 0.020
cell cycle g2 m phase transition GO:0044839 4 0.020
guanosine containing compound metabolic process GO:1901068 4 0.020
peptidyl serine modification GO:0018209 2 0.020
lamellipodium assembly GO:0030032 1 0.020
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.020
neurotransmitter transport GO:0006836 2 0.020
cell morphogenesis involved in differentiation GO:0000904 195 0.020
regulation of phosphorylation GO:0042325 26 0.019
cell projection morphogenesis GO:0048858 244 0.019
neurotransmitter secretion GO:0007269 2 0.019
regulation of signal transduction GO:0009966 225 0.019
regulation of cell activation GO:0050865 1 0.019
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.019
meiotic cell cycle process GO:1903046 3 0.019
alcohol biosynthetic process GO:0046165 2 0.019
developmental process involved in reproduction GO:0003006 27 0.019
Worm Fly
cardiac atrium development GO:0003230 4 0.019
receptor internalization GO:0031623 2 0.019
myofibril assembly GO:0030239 48 0.019
Zebrafish
establishment of rna localization GO:0051236 3 0.019
pronuclear migration GO:0035046 1 0.019
reproductive process GO:0022414 40 0.018
Worm Fly
type i interferon production GO:0032606 2 0.018
alpha amino acid metabolic process GO:1901605 3 0.018
negative regulation of programmed cell death GO:0043069 58 0.018
regulation of neural precursor cell proliferation GO:2000177 3 0.018
cell death in response to oxidative stress GO:0036473 2 0.018
positive regulation of gtpase activity GO:0043547 1 0.018
peptidyl serine phosphorylation GO:0018105 1 0.018
nuclear migration GO:0007097 3 0.018
regulation of microtubule cytoskeleton organization GO:0070507 3 0.018
regulation of protein localization to nucleus GO:1900180 2 0.018
Rat
nucleoside triphosphate metabolic process GO:0009141 9 0.018
Human Worm
regulation of intracellular protein transport GO:0033157 3 0.018
Rat
negative regulation of protein complex assembly GO:0031333 1 0.018
determination of left right symmetry GO:0007368 179 0.018
actin cytoskeleton organization GO:0030036 63 0.018
Zebrafish Fly
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.018
positive regulation of rna metabolic process GO:0051254 59 0.018
nucleic acid metabolic process GO:0090304 244 0.017
regulation of ion transmembrane transporter activity GO:0032412 2 0.017
cellular response to external stimulus GO:0071496 2 0.017
nuclear transport GO:0051169 4 0.017
Rat
nuclear import GO:0051170 3 0.017
Rat
positive regulation of cytokine production GO:0001819 2 0.017
embryo development ending in birth or egg hatching GO:0009792 271 0.017
Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 9 0.017
Human Worm
protein acylation GO:0043543 3 0.017
heterocycle catabolic process GO:0046700 15 0.017
Human Worm
homeostatic process GO:0042592 142 0.017
positive regulation of gene expression GO:0010628 71 0.017
pole plasm assembly GO:0007315 4 0.017
Fly
cell aging GO:0007569 2 0.017
negative regulation of synapse assembly GO:0051964 2 0.017
ribonucleoside catabolic process GO:0042454 7 0.017
Human Worm
regulation of cellular ketone metabolic process GO:0010565 7 0.017
regulation of protein modification process GO:0031399 29 0.017
rna transport GO:0050658 2 0.017
negative regulation of phosphorus metabolic process GO:0010563 13 0.017
positive regulation of dna metabolic process GO:0051054 1 0.017
neuroblast proliferation GO:0007405 2 0.017
cellular response to endogenous stimulus GO:0071495 68 0.016
antimicrobial humoral response GO:0019730 2 0.016
negative regulation of cell communication GO:0010648 96 0.016
protein modification process GO:0036211 100 0.016
Worm
modification dependent protein catabolic process GO:0019941 3 0.016
negative regulation of phosphorylation GO:0042326 6 0.016
negative regulation of cell death GO:0060548 60 0.016
intracellular mrna localization GO:0008298 1 0.016
Fly
positive regulation of gtp catabolic process GO:0033126 1 0.016
regulation of kinase activity GO:0043549 15 0.016
response to drug GO:0042493 3 0.016
cellular response to antibiotic GO:0071236 1 0.016
activation of mapkkk activity GO:0000185 1 0.016
purine ribonucleoside biosynthetic process GO:0046129 2 0.016
regulation of response to biotic stimulus GO:0002831 2 0.016
nucleobase containing compound biosynthetic process GO:0034654 205 0.016
wound healing GO:0042060 90 0.016
sensory perception GO:0007600 39 0.016
phagocytosis engulfment GO:0006911 1 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
regulation of cellular response to oxidative stress GO:1900407 2 0.015
nucleobase containing compound metabolic process GO:0006139 274 0.015
Human Worm
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
intracellular signal transduction GO:0035556 85 0.015
cellular response to nutrient levels GO:0031669 2 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.015
protein dephosphorylation GO:0006470 3 0.015
liver development GO:0001889 96 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
camera type eye development GO:0043010 222 0.015
peripheral nervous system neuron differentiation GO:0048934 28 0.015
regulation of intracellular ph GO:0051453 1 0.015
cellular response to growth factor stimulus GO:0071363 39 0.015
angiogenesis GO:0001525 158 0.015
negative regulation of molecular function GO:0044092 23 0.015
regulation of protein complex disassembly GO:0043244 1 0.015
detection of abiotic stimulus GO:0009582 24 0.015
macromolecular complex disassembly GO:0032984 1 0.015
cellular ketone metabolic process GO:0042180 11 0.015
endomembrane system organization GO:0010256 13 0.015
positive regulation of programmed cell death GO:0043068 29 0.015
germ cell development GO:0007281 22 0.015
Fly
protein heterooligomerization GO:0051291 1 0.014
microtubule polymerization or depolymerization GO:0031109 3 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
Rat
carbohydrate biosynthetic process GO:0016051 1 0.014
energy reserve metabolic process GO:0006112 2 0.014
regulation of ion transmembrane transport GO:0034765 18 0.014
nucleoside phosphate biosynthetic process GO:1901293 21 0.014
organonitrogen compound biosynthetic process GO:1901566 47 0.014
immune system process GO:0002376 241 0.014
negative regulation of phosphate metabolic process GO:0045936 13 0.014
response to growth factor GO:0070848 39 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
muscle cell differentiation GO:0042692 139 0.014
Zebrafish
organic cyclic compound catabolic process GO:1901361 15 0.014
Human Worm
dna metabolic process GO:0006259 27 0.014
purine nucleotide biosynthetic process GO:0006164 20 0.014
regulation of striated muscle contraction GO:0006942 2 0.014
Rat
purine nucleoside monophosphate metabolic process GO:0009126 5 0.014
Human Worm
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.014
posttranscriptional regulation of gene expression GO:0010608 14 0.014
action potential GO:0001508 19 0.014
regulation of cell communication GO:0010646 232 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
mitotic dna integrity checkpoint GO:0044774 4 0.014
regulation of cell cycle GO:0051726 52 0.013
brain development GO:0007420 293 0.013
locomotory behavior GO:0007626 34 0.013
synaptic vesicle transport GO:0048489 1 0.013
nucleoside triphosphate biosynthetic process GO:0009142 2 0.013
hatching GO:0035188 4 0.013
chemosensory behavior GO:0007635 1 0.013
purine nucleoside biosynthetic process GO:0042451 2 0.013
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.013
cellular protein localization GO:0034613 20 0.013
Human Rat
response to amphetamine GO:0001975 1 0.013
positive regulation of myeloid cell differentiation GO:0045639 2 0.013
nucleoside phosphate catabolic process GO:1901292 6 0.013
Human Worm
establishment of localization in cell GO:0051649 77 0.013
Human Rat

hsp90a.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.088
muscular disease DOID:0080000 0 0.088
disease of anatomical entity DOID:7 0 0.088
musculoskeletal system disease DOID:17 0 0.088
muscle tissue disease DOID:66 0 0.088
heart disease DOID:114 0 0.032
cardiomyopathy DOID:0050700 0 0.032
cardiovascular system disease DOID:1287 0 0.032
nervous system disease DOID:863 0 0.017
disease of metabolism DOID:0014667 0 0.013