Danio rerio

0 known processes

drg2

developmentally regulated GTP binding protein 2

(Aliases: wu:fb96b01,MGC101029,wu:fb96a09,zgc:101029)

drg2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.113
nucleic acid metabolic process GO:0090304 244 0.094
meiotic chromosome segregation GO:0045132 3 0.084
nuclear transport GO:0051169 4 0.080
nucleocytoplasmic transport GO:0006913 4 0.079
cellular macromolecule metabolic process GO:0044260 391 0.071
generation of neurons GO:0048699 385 0.070
protein localization to nucleus GO:0034504 3 0.062
nitrogen compound metabolic process GO:0006807 319 0.061
rna metabolic process GO:0016070 219 0.059
heterocycle metabolic process GO:0046483 290 0.055
meiotic cell cycle process GO:1903046 3 0.053
aging GO:0007568 2 0.053
regulation of multicellular organism growth GO:0040014 4 0.046
g1 s transition of mitotic cell cycle GO:0000082 1 0.045
embryo development ending in birth or egg hatching GO:0009792 271 0.045
regulation of cellular metabolic process GO:0031323 320 0.044
multicellular organism growth GO:0035264 4 0.044
regulation of signaling GO:0023051 235 0.043
nucleobase containing compound metabolic process GO:0006139 274 0.042
organic cyclic compound metabolic process GO:1901360 301 0.041
meiotic nuclear division GO:0007126 4 0.041
cell cycle g1 s phase transition GO:0044843 1 0.040
transcription dna templated GO:0006351 181 0.039
growth GO:0040007 174 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.036
single organism transport GO:0044765 206 0.035
organic acid metabolic process GO:0006082 31 0.035
signal transduction GO:0007165 455 0.033
cellular aromatic compound metabolic process GO:0006725 295 0.033
neuron differentiation GO:0030182 353 0.033
rna biosynthetic process GO:0032774 181 0.033
guanosine containing compound metabolic process GO:1901068 4 0.032
protein targeting to nucleus GO:0044744 3 0.032
positive regulation of cellular catabolic process GO:0031331 3 0.032
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.031
regulation of transcription dna templated GO:0006355 213 0.031
negative regulation of biological process GO:0048519 304 0.031
morphogenesis of an epithelium GO:0002009 333 0.030
cellular component biogenesis GO:0044085 178 0.030
protein secretion GO:0009306 1 0.030
organonitrogen compound metabolic process GO:1901564 74 0.030
gtp catabolic process GO:0006184 2 0.030
single organism metabolic process GO:0044710 217 0.030
small molecule metabolic process GO:0044281 77 0.030
atp catabolic process GO:0006200 4 0.029
regulation of gene expression GO:0010468 265 0.029
regulation of response to stimulus GO:0048583 269 0.027
mitochondrion organization GO:0007005 4 0.027
gtp metabolic process GO:0046039 4 0.027
heterocycle biosynthetic process GO:0018130 215 0.027
regulation of nucleic acid templated transcription GO:1903506 213 0.026
nucleoside monophosphate catabolic process GO:0009125 4 0.026
regulation of nucleocytoplasmic transport GO:0046822 2 0.026
regulation of nitrogen compound metabolic process GO:0051171 251 0.026
developmental growth GO:0048589 166 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.026
response to stress GO:0006950 263 0.026
female sex differentiation GO:0046660 4 0.025
cell morphogenesis GO:0000902 289 0.025
positive regulation of biological process GO:0048518 253 0.025
positive regulation of catabolic process GO:0009896 4 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
chordate embryonic development GO:0043009 271 0.025
organelle organization GO:0006996 227 0.024
regulation of macromolecule metabolic process GO:0060255 317 0.024
positive regulation of cell cycle GO:0045787 3 0.024
ribonucleoside monophosphate catabolic process GO:0009158 4 0.024
cellular amino acid metabolic process GO:0006520 7 0.024
gene expression GO:0010467 252 0.024
regulation of mitochondrion organization GO:0010821 1 0.023
protein complex localization GO:0031503 1 0.023
nuclear export GO:0051168 1 0.023
cellular protein catabolic process GO:0044257 4 0.023
single organism localization GO:1902578 225 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.023
guanosine containing compound catabolic process GO:1901069 2 0.023
digestive system development GO:0055123 289 0.023
regulation of protein ubiquitination GO:0031396 3 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
protein import GO:0017038 3 0.022
regulation of biosynthetic process GO:0009889 250 0.022
central nervous system development GO:0007417 387 0.022
protein import into nucleus GO:0006606 3 0.022
oxoacid metabolic process GO:0043436 31 0.022
ribosomal small subunit biogenesis GO:0042274 2 0.021
development of primary female sexual characteristics GO:0046545 4 0.021
response to drug GO:0042493 3 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
sensory organ development GO:0007423 393 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
nucleic acid templated transcription GO:0097659 181 0.021
lipid storage GO:0019915 1 0.020
cellular response to external stimulus GO:0071496 2 0.020
regulation of cell communication GO:0010646 232 0.020
nuclear import GO:0051170 3 0.020
neuron projection development GO:0031175 180 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
cellular nitrogen compound metabolic process GO:0034641 290 0.019
synaptic growth at neuromuscular junction GO:0051124 2 0.019
ovulation cycle GO:0042698 2 0.019
stem cell proliferation GO:0072089 4 0.019
muscle structure development GO:0061061 196 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
digestive tract development GO:0048565 265 0.019
cellular response to stress GO:0033554 62 0.019
cellular component movement GO:0006928 335 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
cell migration GO:0016477 237 0.019
negative regulation of signal transduction GO:0009968 94 0.019
regulation of metabolic process GO:0019222 359 0.019
rna localization GO:0006403 4 0.018
positive regulation of nucleotide catabolic process GO:0030813 1 0.018
intracellular signal transduction GO:0035556 85 0.018
phosphorus metabolic process GO:0006793 109 0.018
cell part morphogenesis GO:0032990 246 0.018
regulation of nucleotide catabolic process GO:0030811 2 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
phagocytosis GO:0006909 3 0.018
tube morphogenesis GO:0035239 349 0.018
purine nucleoside monophosphate catabolic process GO:0009128 4 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
cellular amine metabolic process GO:0044106 2 0.017
female gonad development GO:0008585 4 0.017
regulation of cell activation GO:0050865 1 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
protein modification process GO:0036211 100 0.017
mitotic dna damage checkpoint GO:0044773 4 0.017
organic substance biosynthetic process GO:1901576 289 0.017
cell projection organization GO:0030030 284 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
brain development GO:0007420 293 0.017
biosynthetic process GO:0009058 294 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
positive regulation of rna biosynthetic process GO:1902680 57 0.017
cytoskeleton dependent cytokinesis GO:0061640 3 0.017
positive regulation of macromolecule metabolic process GO:0010604 93 0.017
response to chemical GO:0042221 320 0.017
cytokinesis GO:0000910 3 0.017
cell motility GO:0048870 244 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
positive regulation of transport GO:0051050 2 0.016
positive regulation of translation GO:0045727 1 0.016
regulation of protein targeting GO:1903533 2 0.016
neuron development GO:0048666 262 0.016
cellular component morphogenesis GO:0032989 336 0.016
regulation of primary metabolic process GO:0080090 311 0.016
i kappab kinase nf kappab signaling GO:0007249 4 0.016
regulation of signal transduction GO:0009966 225 0.016
cellular component assembly involved in morphogenesis GO:0010927 107 0.016
somite development GO:0061053 96 0.016
erk1 and erk2 cascade GO:0070371 4 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.015
positive regulation of cellular process GO:0048522 201 0.015
single organism membrane fusion GO:0044801 2 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
maintenance of location GO:0051235 4 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
mesenchymal cell proliferation GO:0010463 1 0.015
protein acetylation GO:0006473 2 0.015
maturation of ssu rrna GO:0030490 1 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
mitotic g2 dna damage checkpoint GO:0007095 3 0.015
amine metabolic process GO:0009308 2 0.015
regulation of protein transport GO:0051223 3 0.015
cell cycle process GO:0022402 53 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
regulation of synapse organization GO:0050807 3 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
eye development GO:0001654 277 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
cell surface receptor signaling pathway GO:0007166 325 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
organic substance transport GO:0071702 58 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
death GO:0016265 121 0.014
ovarian follicle development GO:0001541 2 0.014
protein acylation GO:0043543 3 0.014
positive regulation of gene expression GO:0010628 71 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
regulation of rna metabolic process GO:0051252 224 0.014
ovulation cycle process GO:0022602 2 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
cellular biosynthetic process GO:0044249 286 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
regulation of protein import into nucleus GO:0042306 2 0.013
cognition GO:0050890 1 0.013
microtubule organizing center organization GO:0031023 1 0.013
positive regulation of metabolic process GO:0009893 108 0.013
protein dephosphorylation GO:0006470 3 0.013
programmed cell death GO:0012501 119 0.013
regulation of cellular protein metabolic process GO:0032268 52 0.013
developmental growth involved in morphogenesis GO:0060560 86 0.013
cell projection morphogenesis GO:0048858 244 0.013
apoptotic process GO:0006915 116 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
protein metabolic process GO:0019538 183 0.013
negative regulation of signaling GO:0023057 96 0.013
protein heterooligomerization GO:0051291 1 0.013
localization of cell GO:0051674 244 0.013
centrosome cycle GO:0007098 1 0.013
oocyte maturation GO:0001556 4 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
centrosome duplication GO:0051298 1 0.013
centrosome organization GO:0051297 1 0.013
sensory organ morphogenesis GO:0090596 200 0.013
regulation of developmental process GO:0050793 247 0.013
striated muscle cell development GO:0055002 108 0.013
establishment of rna localization GO:0051236 3 0.013
regulation of gtpase activity GO:0043087 2 0.013
cellular response to oxygen levels GO:0071453 1 0.012
regulation of cell death GO:0010941 103 0.012
secondary metabolic process GO:0019748 3 0.012
g2 dna damage checkpoint GO:0031572 3 0.012
muscle cell development GO:0055001 115 0.012
rna 3 end processing GO:0031123 2 0.012
multicellular organismal reproductive process GO:0048609 35 0.012
female meiotic division GO:0007143 2 0.012
positive regulation of secretion GO:0051047 1 0.012
cellular response to decreased oxygen levels GO:0036294 1 0.012
lymphocyte proliferation GO:0046651 1 0.012
cellular protein metabolic process GO:0044267 129 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
regulation of programmed cell death GO:0043067 101 0.012
macromolecule modification GO:0043412 111 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
cellular response to nutrient levels GO:0031669 2 0.012
regulation of apoptotic process GO:0042981 98 0.012
cell death GO:0008219 121 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
protein modification by small protein conjugation or removal GO:0070647 14 0.011
regulation of synapse assembly GO:0051963 3 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
positive regulation of transcription dna templated GO:0045893 57 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
renal tubule morphogenesis GO:0061333 1 0.011
mesenchymal cell differentiation GO:0048762 87 0.011
ncrna metabolic process GO:0034660 12 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
embryonic organ development GO:0048568 381 0.011
cellular component disassembly GO:0022411 1 0.011
cellular transition metal ion homeostasis GO:0046916 3 0.011
peptidyl lysine acetylation GO:0018394 2 0.011
system process GO:0003008 185 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
autophagy GO:0006914 4 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
positive regulation of rna metabolic process GO:0051254 59 0.011
mitotic cell cycle GO:0000278 64 0.011
establishment of organelle localization GO:0051656 45 0.011
mononuclear cell proliferation GO:0032943 1 0.011
muscle cell differentiation GO:0042692 139 0.011
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
odontogenesis of dentin containing tooth GO:0042475 1 0.011
single organism reproductive process GO:0044702 40 0.010
organelle assembly GO:0070925 110 0.010
single organism nuclear import GO:1902593 3 0.010
positive regulation of cellular biosynthetic process GO:0031328 68 0.010
nucleic acid transport GO:0050657 2 0.010
regulation of binding GO:0051098 3 0.010
wnt signaling pathway GO:0016055 80 0.010
pharyngeal muscle development GO:0043282 4 0.010
somitogenesis GO:0001756 87 0.010
hormone transport GO:0009914 2 0.010
response to alkaloid GO:0043279 2 0.010
regulation of cellular ketone metabolic process GO:0010565 7 0.010
lateral inhibition GO:0046331 1 0.010
cellular protein modification process GO:0006464 100 0.010
mitotic cytokinesis GO:0000281 3 0.010
negative regulation of cell communication GO:0010648 96 0.010
regulation of protein catabolic process GO:0042176 1 0.010
camera type eye development GO:0043010 222 0.010

drg2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.026
neuromuscular disease DOID:440 0 0.017
charcot marie tooth disease DOID:10595 0 0.017
neuropathy DOID:870 0 0.017
sensory system disease DOID:0050155 0 0.015
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
musculoskeletal system disease DOID:17 0 0.011