Danio rerio

0 known processes

pomcb

proopiomelanocortin b

(Aliases: si:ch211-203k16.2)

pomcb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.042
maintenance of location GO:0051235 4 0.041
positive regulation of cellular component biogenesis GO:0044089 3 0.038
positive regulation of transport GO:0051050 2 0.036
adult behavior GO:0030534 2 0.035
signal transduction GO:0007165 455 0.034
regulation of multicellular organism growth GO:0040014 4 0.032
multicellular organism growth GO:0035264 4 0.031
establishment of protein localization to organelle GO:0072594 4 0.031
nuclear transport GO:0051169 4 0.030
aging GO:0007568 2 0.028
nucleocytoplasmic transport GO:0006913 4 0.027
phagocytosis GO:0006909 3 0.027
regulation of cytoplasmic transport GO:1903649 4 0.027
protein localization to nucleus GO:0034504 3 0.026
regulation of establishment of protein localization GO:0070201 4 0.025
stem cell proliferation GO:0072089 4 0.025
regulation of response to stimulus GO:0048583 269 0.024
cellular component movement GO:0006928 335 0.024
extrinsic apoptotic signaling pathway GO:0097191 3 0.023
response to external stimulus GO:0009605 264 0.023
i kappab kinase nf kappab signaling GO:0007249 4 0.023
single organism nuclear import GO:1902593 3 0.023
cellular amine metabolic process GO:0044106 2 0.023
regulation of protein transport GO:0051223 3 0.023
lipid storage GO:0019915 1 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.022
protein targeting to nucleus GO:0044744 3 0.022
sensory perception of chemical stimulus GO:0007606 3 0.022
regulation of reproductive process GO:2000241 4 0.022
amine metabolic process GO:0009308 2 0.022
positive regulation of catabolic process GO:0009896 4 0.021
regulation of cytokine production GO:0001817 3 0.021
cellular component morphogenesis GO:0032989 336 0.021
response to chemical GO:0042221 320 0.021
cellular ketone metabolic process GO:0042180 11 0.021
nuclear import GO:0051170 3 0.021
regulation of nucleocytoplasmic transport GO:0046822 2 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
cytokinesis GO:0000910 3 0.021
morphogenesis of an epithelium GO:0002009 333 0.020
regulation of inflammatory response GO:0050727 2 0.020
cell morphogenesis GO:0000902 289 0.020
regulation of synapse organization GO:0050807 3 0.020
organic substance biosynthetic process GO:1901576 289 0.020
protein import into nucleus GO:0006606 3 0.020
negative regulation of protein phosphorylation GO:0001933 4 0.020
protein import GO:0017038 3 0.020
neurotransmitter transport GO:0006836 2 0.020
positive regulation of protein complex assembly GO:0031334 2 0.020
cell projection morphogenesis GO:0048858 244 0.020
cell surface receptor signaling pathway GO:0007166 325 0.020
synaptic vesicle localization GO:0097479 1 0.020
sensory organ development GO:0007423 393 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.019
gtp metabolic process GO:0046039 4 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
regulation of organelle assembly GO:1902115 4 0.019
regulation of protein complex assembly GO:0043254 3 0.019
cellular macromolecule metabolic process GO:0044260 391 0.019
regulation of cell activation GO:0050865 1 0.019
female sex differentiation GO:0046660 4 0.019
biosynthetic process GO:0009058 294 0.019
mitochondrion organization GO:0007005 4 0.019
gastrulation GO:0007369 208 0.019
mononuclear cell proliferation GO:0032943 1 0.019
negative regulation of biological process GO:0048519 304 0.019
transport GO:0006810 220 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.018
cellular nitrogen compound metabolic process GO:0034641 290 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
regulation of cell communication GO:0010646 232 0.018
positive regulation of immune effector process GO:0002699 3 0.018
gtp catabolic process GO:0006184 2 0.018
regulation of cell shape GO:0008360 1 0.018
embryonic organ development GO:0048568 381 0.018
response to stress GO:0006950 263 0.018
regulation of metal ion transport GO:0010959 4 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
regulation of sequestering of calcium ion GO:0051282 4 0.018
single organism localization GO:1902578 225 0.018
negative regulation of kinase activity GO:0033673 4 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
oxoacid metabolic process GO:0043436 31 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
regulation of synapse assembly GO:0051963 3 0.018
stem cell maintenance GO:0019827 4 0.018
golgi vesicle transport GO:0048193 3 0.017
guanosine containing compound catabolic process GO:1901069 2 0.017
camera type eye development GO:0043010 222 0.017
cell part morphogenesis GO:0032990 246 0.017
small molecule catabolic process GO:0044282 3 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
sequestering of calcium ion GO:0051208 3 0.017
organic acid metabolic process GO:0006082 31 0.017
regulation of binding GO:0051098 3 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
neuroblast proliferation GO:0007405 2 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
eye development GO:0001654 277 0.017
response to drug GO:0042493 3 0.017
establishment of localization GO:0051234 244 0.017
positive regulation of cell cycle GO:0045787 3 0.017
negative regulation of protein transport GO:0051224 3 0.017
cellular component disassembly GO:0022411 1 0.017
digestive tract development GO:0048565 265 0.017
positive regulation of cytokine production GO:0001819 2 0.016
regulation of blood pressure GO:0008217 1 0.016
liver development GO:0001889 96 0.016
regulation of nitrogen compound metabolic process GO:0051171 251 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.016
lipid catabolic process GO:0016042 4 0.016
cellular response to external stimulus GO:0071496 2 0.016
head development GO:0060322 303 0.016
protein metabolic process GO:0019538 183 0.016
heterocycle metabolic process GO:0046483 290 0.016
regulation of protein catabolic process GO:0042176 1 0.016
response to nutrient GO:0007584 3 0.016
nitrogen compound metabolic process GO:0006807 319 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
response to carbohydrate GO:0009743 3 0.016
protein localization to plasma membrane GO:0072659 1 0.016
immune system process GO:0002376 241 0.016
regulation of protein targeting GO:1903533 2 0.016
regulation of signal transduction GO:0009966 225 0.016
regulation of transporter activity GO:0032409 2 0.016
cellular protein catabolic process GO:0044257 4 0.016
negative regulation of cellular process GO:0048523 283 0.016
system process GO:0003008 185 0.016
cellular response to nutrient levels GO:0031669 2 0.016
organic cyclic compound metabolic process GO:1901360 301 0.016
peptide transport GO:0015833 1 0.016
hormone secretion GO:0046879 2 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
regulation of macromolecule metabolic process GO:0060255 317 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
leukocyte proliferation GO:0070661 1 0.016
blood vessel development GO:0001568 246 0.016
proteasomal protein catabolic process GO:0010498 2 0.015
cell matrix adhesion GO:0007160 4 0.015
single organism metabolic process GO:0044710 217 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
cell migration GO:0016477 237 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
cognition GO:0050890 1 0.015
muscle structure development GO:0061061 196 0.015
regulation of blood vessel size GO:0050880 2 0.015
cellular amide metabolic process GO:0043603 4 0.015
somatic muscle development GO:0007525 4 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.015
hormone transport GO:0009914 2 0.015
positive regulation of cell adhesion GO:0045785 1 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
sequestering of metal ion GO:0051238 3 0.015
lymphocyte proliferation GO:0046651 1 0.015
protein complex disassembly GO:0043241 1 0.015
regulation of production of molecular mediator of immune response GO:0002700 1 0.015
heart development GO:0007507 313 0.015
female gonad development GO:0008585 4 0.015
nucleobase containing compound metabolic process GO:0006139 274 0.015
regulation of autophagy GO:0010506 3 0.015
negative regulation of sequestering of calcium ion GO:0051283 4 0.015
negative regulation of cytoplasmic transport GO:1903650 2 0.015
regulation of circadian rhythm GO:0042752 4 0.015
nucleic acid templated transcription GO:0097659 181 0.015
secondary metabolic process GO:0019748 3 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.015
regulation of mrna processing GO:0050684 3 0.015
vasculature development GO:0001944 278 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
production of molecular mediator of immune response GO:0002440 2 0.014
rna metabolic process GO:0016070 219 0.014
regulation of tube size GO:0035150 2 0.014
regulation of primary metabolic process GO:0080090 311 0.014
tube closure GO:0060606 1 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
release of sequestered calcium ion into cytosol GO:0051209 3 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
cell projection organization GO:0030030 284 0.014
neuron differentiation GO:0030182 353 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
synaptic vesicle transport GO:0048489 1 0.014
tube morphogenesis GO:0035239 349 0.014
single fertilization GO:0007338 3 0.014
negative regulation of catabolic process GO:0009895 3 0.014
cellular lipid catabolic process GO:0044242 3 0.014
negative regulation of secretion GO:0051048 2 0.014
chordate embryonic development GO:0043009 271 0.014
tissue remodeling GO:0048771 4 0.014
phagocytosis engulfment GO:0006911 1 0.014
positive regulation of cell activation GO:0050867 1 0.014
regulation of cellular metabolic process GO:0031323 320 0.014
protein acetylation GO:0006473 2 0.014
cellular component biogenesis GO:0044085 178 0.014
cellular biosynthetic process GO:0044249 286 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
nucleic acid metabolic process GO:0090304 244 0.014
phosphatidylinositol mediated signaling GO:0048015 2 0.014
regulation of cell projection assembly GO:0060491 4 0.014
compound eye development GO:0048749 2 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
alcohol biosynthetic process GO:0046165 2 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
small molecule metabolic process GO:0044281 77 0.014
digestive system development GO:0055123 289 0.014
cellular response to starvation GO:0009267 1 0.014
generation of neurons GO:0048699 385 0.014
regionalization GO:0003002 274 0.014
cellular response to oxygen levels GO:0071453 1 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
cell motility GO:0048870 244 0.014
exocytosis GO:0006887 1 0.014
neuron development GO:0048666 262 0.013
regulation of biological quality GO:0065008 263 0.013
anterior posterior pattern specification GO:0009952 152 0.013
neuron neuron synaptic transmission GO:0007270 1 0.013
positive regulation of chromatin modification GO:1903310 1 0.013
interspecies interaction between organisms GO:0044419 4 0.013
lateral inhibition GO:0046331 1 0.013
cytosolic calcium ion transport GO:0060401 3 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
inositol lipid mediated signaling GO:0048017 2 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
negative regulation of intracellular transport GO:0032387 3 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
regulation of metabolic process GO:0019222 359 0.013
determination of left right symmetry GO:0007368 179 0.013
amino acid transport GO:0006865 2 0.013
localization of cell GO:0051674 244 0.013
central nervous system development GO:0007417 387 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.013
macromolecular complex disassembly GO:0032984 1 0.013
autophagy GO:0006914 4 0.013
response to alkaloid GO:0043279 2 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
brain development GO:0007420 293 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
single organism transport GO:0044765 206 0.013
membrane invagination GO:0010324 1 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
endosomal transport GO:0016197 2 0.013
calcium ion transport into cytosol GO:0060402 3 0.013
atp catabolic process GO:0006200 4 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
regulation of dendrite development GO:0050773 3 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
locomotion GO:0040011 313 0.013
gene expression GO:0010467 252 0.013
response to glucose GO:0009749 3 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
growth GO:0040007 174 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.013
regulation of hormone secretion GO:0046883 2 0.013
negative regulation of secretion by cell GO:1903531 2 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.013
chemosensory behavior GO:0007635 1 0.013
regulation of developmental process GO:0050793 247 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
response to monosaccharide GO:0034284 3 0.013
positive regulation of secretion by cell GO:1903532 1 0.012
response to hexose GO:0009746 3 0.012
rna localization GO:0006403 4 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
carbohydrate homeostasis GO:0033500 1 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.012
actin filament based movement GO:0030048 1 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
regulation of biosynthetic process GO:0009889 250 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
stem cell division GO:0017145 1 0.012
cell substrate adhesion GO:0031589 4 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
protein acylation GO:0043543 3 0.012
hepaticobiliary system development GO:0061008 98 0.012
protein polymerization GO:0051258 4 0.012
developmental growth GO:0048589 166 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
organic cyclic compound biosynthetic process GO:1901362 223 0.012
development of primary female sexual characteristics GO:0046545 4 0.012
organic acid catabolic process GO:0016054 3 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
gland development GO:0048732 143 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.012
blood vessel morphogenesis GO:0048514 216 0.012
regulation of calcium ion transport GO:0051924 2 0.012
negative regulation of cell communication GO:0010648 96 0.012
regulation of gene expression GO:0010468 265 0.012
cellular response to hypoxia GO:0071456 1 0.012
digestive tract morphogenesis GO:0048546 231 0.012
b cell activation GO:0042113 2 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
negative regulation of signal transduction GO:0009968 94 0.012
single organism organelle organization GO:1902589 199 0.012
positive regulation of secretion GO:0051047 1 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
regulation of signaling GO:0023051 235 0.012
response to uv GO:0009411 3 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
carboxylic acid catabolic process GO:0046395 3 0.012
fatty acid catabolic process GO:0009062 1 0.012
protein heterooligomerization GO:0051291 1 0.012
regulation of gtpase activity GO:0043087 2 0.012
meiotic cell cycle process GO:1903046 3 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
ameboidal type cell migration GO:0001667 143 0.012
cellular response to radiation GO:0071478 4 0.012
toll like receptor signaling pathway GO:0002224 4 0.012
regulation of protein polymerization GO:0032271 2 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
positive regulation of protein polymerization GO:0032273 2 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
regulation of ph GO:0006885 3 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
heart looping GO:0001947 94 0.011
protein secretion GO:0009306 1 0.011
adherens junction organization GO:0034332 4 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
negative regulation of defense response GO:0031348 2 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
rhombomere 5 development GO:0021571 4 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
negative regulation of reproductive process GO:2000242 3 0.011
positive regulation of histone modification GO:0031058 1 0.011
negative regulation of signaling GO:0023057 96 0.011
determination of bilateral symmetry GO:0009855 204 0.011
rna biosynthetic process GO:0032774 181 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
developmental programmed cell death GO:0010623 4 0.011
response to corticosteroid GO:0031960 1 0.011
organelle assembly GO:0070925 110 0.011
multi organism cellular process GO:0044764 2 0.011
sensory perception of smell GO:0007608 2 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
cilium morphogenesis GO:0060271 85 0.011
peptidyl serine modification GO:0018209 2 0.011
dicarboxylic acid transport GO:0006835 1 0.011
response to xenobiotic stimulus GO:0009410 45 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
cellular protein metabolic process GO:0044267 129 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
response to wounding GO:0009611 116 0.011
fertilization GO:0009566 3 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
negative regulation of cytokine production GO:0001818 1 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
sensory perception of pain GO:0019233 1 0.011
intracellular signal transduction GO:0035556 85 0.011
organelle fusion GO:0048284 3 0.011
neurotransmitter secretion GO:0007269 2 0.011
mitotic cytokinesis GO:0000281 3 0.011
antimicrobial humoral response GO:0019730 2 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
primary neural tube formation GO:0014020 1 0.011
cellular response to light stimulus GO:0071482 4 0.011
striated muscle tissue development GO:0014706 110 0.011
organelle organization GO:0006996 227 0.011
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.011
cell death GO:0008219 121 0.011
response to organic substance GO:0010033 153 0.010
spermatid development GO:0007286 2 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
cilium assembly GO:0042384 58 0.010
retina development in camera type eye GO:0060041 146 0.010
negative regulation of multi organism process GO:0043901 3 0.010
regulation of rna metabolic process GO:0051252 224 0.010
regulation of response to extracellular stimulus GO:0032104 1 0.010
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.010
actin filament polymerization GO:0030041 2 0.010
viral process GO:0016032 1 0.010
response to external biotic stimulus GO:0043207 97 0.010
sensory organ morphogenesis GO:0090596 200 0.010
macroautophagy GO:0016236 1 0.010
membrane fusion GO:0061025 2 0.010
cellular response to reactive oxygen species GO:0034614 2 0.010
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.010
superoxide metabolic process GO:0006801 2 0.010
regulation of neurotransmitter transport GO:0051588 1 0.010
regulation of response to biotic stimulus GO:0002831 2 0.010
response to topologically incorrect protein GO:0035966 2 0.010
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.010
cytoplasm organization GO:0007028 4 0.010
single organism membrane fusion GO:0044801 2 0.010
regulation of gtp catabolic process GO:0033124 2 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
embryonic skeletal system development GO:0048706 97 0.010
glucose homeostasis GO:0042593 1 0.010
angiogenesis GO:0001525 158 0.010
regulation of apoptotic process GO:0042981 98 0.010

pomcb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.016
cardiovascular system disease DOID:1287 0 0.015
disease of metabolism DOID:0014667 0 0.015
musculoskeletal system disease DOID:17 0 0.014
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.012
immune system disease DOID:2914 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.010