Danio rerio

0 known processes

si:dkeyp-55f12.4

si:dkeyp-55f12.4

(Aliases: zgc:112233,MGC112233)

si:dkeyp-55f12.4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
organelle fusion GO:0048284 3 0.086
aging GO:0007568 2 0.071
larval development GO:0002164 2 0.068
signal transduction GO:0007165 455 0.056
golgi vesicle transport GO:0048193 3 0.041
exocytosis GO:0006887 1 0.034
protein localization to plasma membrane GO:0072659 1 0.034
heart development GO:0007507 313 0.033
cellular response to external stimulus GO:0071496 2 0.031
regulation of reproductive process GO:2000241 4 0.030
embryonic organ morphogenesis GO:0048562 274 0.030
negative regulation of cellular process GO:0048523 283 0.029
organic substance biosynthetic process GO:1901576 289 0.029
positive regulation of apoptotic signaling pathway GO:2001235 1 0.029
regulation of response to stimulus GO:0048583 269 0.029
regulation of signal transduction GO:0009966 225 0.029
synaptic vesicle transport GO:0048489 1 0.028
maintenance of location GO:0051235 4 0.027
regulation of cellular ketone metabolic process GO:0010565 7 0.027
lipid storage GO:0019915 1 0.026
endosomal transport GO:0016197 2 0.026
regulation of metabolic process GO:0019222 359 0.026
ubiquitin dependent protein catabolic process GO:0006511 3 0.026
morphogenesis of an epithelium GO:0002009 333 0.026
phagocytosis GO:0006909 3 0.025
regulation of biological quality GO:0065008 263 0.025
multicellular organism growth GO:0035264 4 0.025
maternal determination of anterior posterior axis embryo GO:0008358 4 0.025
response to stress GO:0006950 263 0.025
regionalization GO:0003002 274 0.025
establishment of protein localization to plasma membrane GO:0090002 1 0.025
positive regulation of cell cycle GO:0045787 3 0.025
negative regulation of nuclear division GO:0051784 3 0.024
modification dependent protein catabolic process GO:0019941 3 0.024
cellular response to nutrient levels GO:0031669 2 0.024
regulation of cell communication GO:0010646 232 0.024
regulation of synaptic plasticity GO:0048167 1 0.024
tube morphogenesis GO:0035239 349 0.024
cytoskeleton dependent cytokinesis GO:0061640 3 0.023
rna localization GO:0006403 4 0.023
cellular ketone metabolic process GO:0042180 11 0.023
biosynthetic process GO:0009058 294 0.023
guanosine containing compound catabolic process GO:1901069 2 0.023
cellular macromolecule metabolic process GO:0044260 391 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.022
amine metabolic process GO:0009308 2 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
negative regulation of biological process GO:0048519 304 0.021
establishment of protein localization to organelle GO:0072594 4 0.021
multi organism process GO:0051704 134 0.020
single organism localization GO:1902578 225 0.020
regulation of synapse organization GO:0050807 3 0.020
autophagy GO:0006914 4 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
heart morphogenesis GO:0003007 156 0.020
antimicrobial humoral response GO:0019730 2 0.020
determination of bilateral symmetry GO:0009855 204 0.020
cellular amine metabolic process GO:0044106 2 0.020
gtp metabolic process GO:0046039 4 0.020
cellular component biogenesis GO:0044085 178 0.020
extrinsic apoptotic signaling pathway GO:0097191 3 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
stem cell maintenance GO:0019827 4 0.020
regulation of signaling GO:0023051 235 0.019
regulation of meiotic cell cycle GO:0051445 1 0.019
pole plasm assembly GO:0007315 4 0.019
organic cyclic compound metabolic process GO:1901360 301 0.019
single organism membrane fusion GO:0044801 2 0.019
hematopoietic or lymphoid organ development GO:0048534 191 0.019
hemopoiesis GO:0030097 183 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
heart looping GO:0001947 94 0.019
regulation of synapse assembly GO:0051963 3 0.019
establishment of synaptic vesicle localization GO:0097480 1 0.019
negative regulation of protein kinase activity GO:0006469 4 0.019
nucleic acid transport GO:0050657 2 0.019
response to glucocorticoid GO:0051384 1 0.019
sensory organ development GO:0007423 393 0.019
regulation of cell activation GO:0050865 1 0.019
positive regulation of translation GO:0045727 1 0.019
gtp catabolic process GO:0006184 2 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.018
stem cell division GO:0017145 1 0.018
regulation of cytokine production GO:0001817 3 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
glial cell migration GO:0008347 3 0.018
nuclear import GO:0051170 3 0.018
response to topologically incorrect protein GO:0035966 2 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
immune system development GO:0002520 191 0.018
synaptic vesicle localization GO:0097479 1 0.018
positive regulation of catabolic process GO:0009896 4 0.018
cellular respiration GO:0045333 3 0.017
regulation of protein complex assembly GO:0043254 3 0.017
female sex differentiation GO:0046660 4 0.017
positive regulation of transport GO:0051050 2 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
nuclear transport GO:0051169 4 0.017
peptidyl serine phosphorylation GO:0018105 1 0.017
vacuolar transport GO:0007034 2 0.017
mononuclear cell proliferation GO:0032943 1 0.017
synaptic vesicle endocytosis GO:0048488 1 0.017
embryonic heart tube morphogenesis GO:0003143 108 0.017
compound eye development GO:0048749 2 0.017
organonitrogen compound metabolic process GO:1901564 74 0.016
epithelial tube morphogenesis GO:0060562 148 0.016
response to nutrient GO:0007584 3 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
cytokinesis GO:0000910 3 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
protein secretion GO:0009306 1 0.016
cellular protein catabolic process GO:0044257 4 0.016
regulation of gtpase activity GO:0043087 2 0.016
protein homooligomerization GO:0051260 3 0.016
interaction with host GO:0051701 4 0.016
protein stabilization GO:0050821 2 0.016
apoptotic process involved in development GO:1902742 2 0.016
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
homeostatic process GO:0042592 142 0.016
establishment of localization GO:0051234 244 0.016
cellular response to light stimulus GO:0071482 4 0.015
er nucleus signaling pathway GO:0006984 2 0.015
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.015
signal transduction in absence of ligand GO:0038034 1 0.015
regulation of blood vessel size GO:0050880 2 0.015
cellular response to starvation GO:0009267 1 0.015
protein import into nucleus GO:0006606 3 0.015
specification of symmetry GO:0009799 204 0.015
single organism nuclear import GO:1902593 3 0.015
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.015
peptidyl serine modification GO:0018209 2 0.015
embryonic limb morphogenesis GO:0030326 2 0.015
embryonic organ development GO:0048568 381 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
locomotion GO:0040011 313 0.015
protein localization to nucleus GO:0034504 3 0.015
b cell activation GO:0042113 2 0.015
regulation of intracellular protein transport GO:0033157 3 0.014
cellular response to radiation GO:0071478 4 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
response to unfolded protein GO:0006986 2 0.014
cellular transition metal ion homeostasis GO:0046916 3 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
eye development GO:0001654 277 0.014
membrane fusion GO:0061025 2 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
regulation of blood pressure GO:0008217 1 0.014
protein k48 linked ubiquitination GO:0070936 1 0.014
response to organic substance GO:0010033 153 0.014
organelle organization GO:0006996 227 0.014
olfactory lobe development GO:0021988 4 0.014
regulation of programmed cell death GO:0043067 101 0.014
nucleobase containing compound transport GO:0015931 2 0.014
centrosome organization GO:0051297 1 0.014
regulation of protein transport GO:0051223 3 0.014
oocyte anterior posterior axis specification GO:0007314 4 0.014
small molecule metabolic process GO:0044281 77 0.014
regulation of binding GO:0051098 3 0.014
response to corticosteroid GO:0031960 1 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
b cell differentiation GO:0030183 1 0.014
nitrogen compound metabolic process GO:0006807 319 0.014
regulation of jak stat cascade GO:0046425 3 0.013
regulation of tube size GO:0035150 2 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
single organism metabolic process GO:0044710 217 0.013
sequestering of metal ion GO:0051238 3 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
determination of left right symmetry GO:0007368 179 0.013
cellular nitrogen compound metabolic process GO:0034641 290 0.013
cellular component maintenance GO:0043954 3 0.013
negative regulation of map kinase activity GO:0043407 2 0.013
ovulation cycle process GO:0022602 2 0.013
system process GO:0003008 185 0.013
blood vessel development GO:0001568 246 0.013
response to external biotic stimulus GO:0043207 97 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
mitochondrion organization GO:0007005 4 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
golgi organization GO:0007030 1 0.013
synaptic vesicle recycling GO:0036465 1 0.013
regulation of protein binding GO:0043393 3 0.013
response to amino acid GO:0043200 2 0.013
germ line stem cell maintenance GO:0030718 2 0.013
cell death GO:0008219 121 0.013
cellular modified amino acid metabolic process GO:0006575 3 0.013
protein acylation GO:0043543 3 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
death GO:0016265 121 0.013
muscle structure development GO:0061061 196 0.013
secondary metabolic process GO:0019748 3 0.013
regulation of organ growth GO:0046620 3 0.013
heterocycle metabolic process GO:0046483 290 0.013
adult behavior GO:0030534 2 0.013
leukocyte proliferation GO:0070661 1 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
multicellular organismal response to stress GO:0033555 2 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
regulation of protein localization to plasma membrane GO:1903076 1 0.012
cilium morphogenesis GO:0060271 85 0.012
oxoacid metabolic process GO:0043436 31 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
cytoplasm organization GO:0007028 4 0.012
protein import GO:0017038 3 0.012
regulation of macromolecule metabolic process GO:0060255 317 0.012
regulation of response to cytokine stimulus GO:0060759 3 0.012
protein metabolic process GO:0019538 183 0.012
protein targeting to nucleus GO:0044744 3 0.012
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
negative regulation of kinase activity GO:0033673 4 0.012
spermatid differentiation GO:0048515 2 0.012
response to uv GO:0009411 3 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
regulation of oocyte development GO:0060281 3 0.012
activation of mapk activity GO:0000187 3 0.012
entrainment of circadian clock GO:0009649 2 0.012
muscle cell differentiation GO:0042692 139 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
cortical cytoskeleton organization GO:0030865 1 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
spindle assembly GO:0051225 2 0.012
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.012
regulation of apoptotic process GO:0042981 98 0.012
protein polyubiquitination GO:0000209 4 0.012
positive regulation of cytokine production GO:0001819 2 0.012
female gonad development GO:0008585 4 0.012
spermatid development GO:0007286 2 0.012
positive regulation of cellular process GO:0048522 201 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
cellular response to unfolded protein GO:0034620 2 0.012
positive regulation of ras protein signal transduction GO:0046579 1 0.012
stem cell proliferation GO:0072089 4 0.012
microtubule organizing center organization GO:0031023 1 0.012
phototransduction GO:0007602 2 0.012
apoptotic process GO:0006915 116 0.012
regulation of stem cell differentiation GO:2000736 4 0.012
developmental programmed cell death GO:0010623 4 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
glucose homeostasis GO:0042593 1 0.011
transport GO:0006810 220 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
negative regulation of catabolic process GO:0009895 3 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
er to golgi vesicle mediated transport GO:0006888 1 0.011
tissue remodeling GO:0048771 4 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
response to external stimulus GO:0009605 264 0.011
endoplasmic reticulum unfolded protein response GO:0030968 2 0.011
negative regulation of reproductive process GO:2000242 3 0.011
chordate embryonic development GO:0043009 271 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
growth GO:0040007 174 0.011
organic acid metabolic process GO:0006082 31 0.011
regulation of gene expression GO:0010468 265 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
positive regulation of cell activation GO:0050867 1 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
lymphocyte proliferation GO:0046651 1 0.011
hormone transport GO:0009914 2 0.011
response to chemical GO:0042221 320 0.011
atp catabolic process GO:0006200 4 0.011
regulation of nitrogen compound metabolic process GO:0051171 251 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
interspecies interaction between organisms GO:0044419 4 0.011
meiotic nuclear division GO:0007126 4 0.011
cell substrate adhesion GO:0031589 4 0.011
response to biotic stimulus GO:0009607 97 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
immune system process GO:0002376 241 0.011
carbohydrate homeostasis GO:0033500 1 0.011
ovulation cycle GO:0042698 2 0.011
cellular response to topologically incorrect protein GO:0035967 2 0.011
calcium mediated signaling GO:0019722 2 0.011
regulation of protein targeting GO:1903533 2 0.011
embryonic heart tube development GO:0035050 133 0.011
kupffer s vesicle development GO:0070121 50 0.011
single organism organelle organization GO:1902589 199 0.011
post golgi vesicle mediated transport GO:0006892 1 0.011
negative regulation of multi organism process GO:0043901 3 0.011
positive regulation of multi organism process GO:0043902 3 0.011
renal tubule morphogenesis GO:0061333 1 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.011
positive regulation of gtpase activity GO:0043547 1 0.010
negative regulation of cell communication GO:0010648 96 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
regulation of primary metabolic process GO:0080090 311 0.010
digestive system development GO:0055123 289 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
regulation of cellular metabolic process GO:0031323 320 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
regulation of neuronal synaptic plasticity GO:0048168 1 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
regulation of ph GO:0006885 3 0.010
toxin metabolic process GO:0009404 1 0.010
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.010
intracellular signal transduction GO:0035556 85 0.010
morphogenesis of an epithelial fold GO:0060571 1 0.010
macroautophagy GO:0016236 1 0.010
iron ion homeostasis GO:0055072 4 0.010
odontogenesis of dentin containing tooth GO:0042475 1 0.010
cellular biosynthetic process GO:0044249 286 0.010
gene expression GO:0010467 252 0.010
negative regulation of signaling GO:0023057 96 0.010

si:dkeyp-55f12.4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
nervous system disease DOID:863 0 0.032
disease of metabolism DOID:0014667 0 0.027
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.018
eye disease DOID:5614 0 0.018
musculoskeletal system disease DOID:17 0 0.013
inherited metabolic disorder DOID:655 0 0.013
lysosomal storage disease DOID:3211 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011