Danio rerio

0 known processes

kdm5bb

lysine (K)-specific demethylase 5Bb

(Aliases: jarid1bb,zgc:85741,cb264,wu:fc44h11,plu1)

kdm5bb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.512
cellular macromolecule metabolic process GO:0044260 391 0.325
Human Fly
aging GO:0007568 2 0.308
organic substance biosynthetic process GO:1901576 289 0.266
Human Fly
signal transduction GO:0007165 455 0.203
negative regulation of cellular process GO:0048523 283 0.201
Human Zebrafish
transcription dna templated GO:0006351 181 0.129
Human Fly
nitrogen compound metabolic process GO:0006807 319 0.121
Human Fly
aromatic compound biosynthetic process GO:0019438 217 0.109
Human Fly
negative regulation of biological process GO:0048519 304 0.104
Human Zebrafish
maintenance of location GO:0051235 4 0.102
heterocycle biosynthetic process GO:0018130 215 0.102
Human Fly
regulation of cell shape GO:0008360 1 0.101
regulation of nitrogen compound metabolic process GO:0051171 251 0.101
Human Fly
regulation of rna biosynthetic process GO:2001141 213 0.099
Human Fly
sensory organ development GO:0007423 393 0.098
lipid storage GO:0019915 1 0.093
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.091
Human Fly
biosynthetic process GO:0009058 294 0.091
Human Fly
positive regulation of biological process GO:0048518 253 0.085
Fly
organic cyclic compound metabolic process GO:1901360 301 0.078
Human Fly
regulation of biological quality GO:0065008 263 0.077
regulation of developmental process GO:0050793 247 0.075
nucleic acid metabolic process GO:0090304 244 0.074
Human Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.073
Fly
regulation of rna metabolic process GO:0051252 224 0.071
Human Fly
nucleobase containing compound metabolic process GO:0006139 274 0.069
Human Fly
cellular component movement GO:0006928 335 0.068
cellular macromolecule biosynthetic process GO:0034645 224 0.066
Human Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.064
Human Fly
regulation of ph GO:0006885 3 0.063
cellular biosynthetic process GO:0044249 286 0.063
Human Fly
heterocycle metabolic process GO:0046483 290 0.063
Human Fly
regulation of primary metabolic process GO:0080090 311 0.062
Human Fly
rna biosynthetic process GO:0032774 181 0.061
Human Fly
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.060
regulation of cellular biosynthetic process GO:0031326 245 0.060
Human Fly
positive regulation of cellular metabolic process GO:0031325 94 0.060
Fly
regulation of signal transduction GO:0009966 225 0.059
regulation of macromolecule metabolic process GO:0060255 317 0.054
Human Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.054
Human Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.053
nucleobase containing compound biosynthetic process GO:0034654 205 0.052
Human Fly
multicellular organism growth GO:0035264 4 0.051
regulation of signaling GO:0023051 235 0.049
regulation of multicellular organism growth GO:0040014 4 0.048
cell surface receptor signaling pathway GO:0007166 325 0.048
regulation of macromolecule biosynthetic process GO:0010556 225 0.047
Human Fly
regulation of metabolic process GO:0019222 359 0.046
Human Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.046
Human Fly
regulation of multicellular organismal process GO:0051239 277 0.045
regulation of circadian rhythm GO:0042752 4 0.045
positive regulation of cellular catabolic process GO:0031331 3 0.045
positive regulation of cellular biosynthetic process GO:0031328 68 0.045
Fly
cellular component morphogenesis GO:0032989 336 0.044
lymphatic endothelial cell differentiation GO:0060836 1 0.044
macromolecule modification GO:0043412 111 0.043
Human Fly
positive regulation of cellular process GO:0048522 201 0.043
Fly
cellular protein modification process GO:0006464 100 0.042
Human Fly
entrainment of circadian clock GO:0009649 2 0.042
eye development GO:0001654 277 0.042
regulation of biosynthetic process GO:0009889 250 0.042
Human Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.041
Human Fly
embryonic organ development GO:0048568 381 0.041
regulation of cellular response to growth factor stimulus GO:0090287 35 0.040
muscle structure development GO:0061061 196 0.040
positive regulation of metabolic process GO:0009893 108 0.039
Fly
gene expression GO:0010467 252 0.038
Human Fly
cell migration GO:0016477 237 0.038
cation homeostasis GO:0055080 33 0.038
positive regulation of catabolic process GO:0009896 4 0.037
neuron development GO:0048666 262 0.037
response to stress GO:0006950 263 0.037
cellular aromatic compound metabolic process GO:0006725 295 0.036
Human Fly
cardiac cell fate commitment GO:0060911 1 0.036
generation of neurons GO:0048699 385 0.036
meiotic nuclear division GO:0007126 4 0.036
female sex differentiation GO:0046660 4 0.035
positive regulation of transport GO:0051050 2 0.035
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.035
Fly
protein metabolic process GO:0019538 183 0.034
Human Fly
single organism nuclear import GO:1902593 3 0.033
compound eye development GO:0048749 2 0.033
regulation of skeletal muscle fiber development GO:0048742 2 0.033
macromolecule biosynthetic process GO:0009059 227 0.033
Human Fly
localization of cell GO:0051674 244 0.033
regulation of localization GO:0032879 104 0.032
single organism organelle organization GO:1902589 199 0.031
Human Fly
negative regulation of synapse assembly GO:0051964 2 0.031
regulation of apoptotic process GO:0042981 98 0.031
Zebrafish
phagocytosis GO:0006909 3 0.030
ion homeostasis GO:0050801 41 0.030
rna metabolic process GO:0016070 219 0.030
Human Fly
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.030
metal ion homeostasis GO:0055065 26 0.030
endosomal transport GO:0016197 2 0.029
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.029
response to chemical GO:0042221 320 0.029
locomotion GO:0040011 313 0.029
circadian sleep wake cycle process GO:0022410 2 0.029
cellular response to chemical stimulus GO:0070887 157 0.029
regulation of programmed cell death GO:0043067 101 0.028
Zebrafish
cell substrate adhesion GO:0031589 4 0.028
cell death GO:0008219 121 0.028
Zebrafish
blood vessel morphogenesis GO:0048514 216 0.028
morphogenesis of an epithelium GO:0002009 333 0.027
regulation of transcription dna templated GO:0006355 213 0.027
Human Fly
dna templated transcription elongation GO:0006354 3 0.027
homeostatic process GO:0042592 142 0.026
female gonad development GO:0008585 4 0.026
regulation of cellular metabolic process GO:0031323 320 0.026
Human Fly
regulation of multicellular organismal development GO:2000026 223 0.026
protein modification process GO:0036211 100 0.026
Human Fly
blood vessel development GO:0001568 246 0.025
cell motility GO:0048870 244 0.025
adult behavior GO:0030534 2 0.025
regionalization GO:0003002 274 0.025
small gtpase mediated signal transduction GO:0007264 8 0.025
ventricular cardiac muscle tissue development GO:0003229 3 0.025
regulation of cell motility GO:2000145 46 0.025
regulation of protein ubiquitination GO:0031396 3 0.025
organelle organization GO:0006996 227 0.025
Human Fly
central nervous system development GO:0007417 387 0.025
regulation of cellular ketone metabolic process GO:0010565 7 0.025
specification of axis polarity GO:0065001 4 0.024
transport GO:0006810 220 0.024
rna export from nucleus GO:0006405 1 0.024
negative regulation of cell migration GO:0030336 17 0.024
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.024
neuron differentiation GO:0030182 353 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.023
Fly
rna localization GO:0006403 4 0.023
growth GO:0040007 174 0.023
regulation of response to stimulus GO:0048583 269 0.023
cellular protein metabolic process GO:0044267 129 0.023
Human Fly
establishment of localization GO:0051234 244 0.023
angiogenesis GO:0001525 158 0.023
regulation of dna templated transcription elongation GO:0032784 3 0.023
regulation of locomotion GO:0040012 55 0.022
anterior posterior pattern specification GO:0009952 152 0.022
embryonic organ morphogenesis GO:0048562 274 0.022
muscle organ development GO:0007517 101 0.022
photoreceptor cell fate commitment GO:0046552 1 0.022
developmental growth GO:0048589 166 0.022
immune system process GO:0002376 241 0.022
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.022
positive regulation of dna templated transcription elongation GO:0032786 1 0.022
heart development GO:0007507 313 0.022
embryonic heart tube development GO:0035050 133 0.021
ph reduction GO:0045851 1 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.021
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.021
neuron projection guidance GO:0097485 86 0.021
negative regulation of cellular metabolic process GO:0031324 77 0.021
Human
synaptic growth at neuromuscular junction GO:0051124 2 0.021
regulation of skeletal muscle tissue development GO:0048641 4 0.021
response to external stimulus GO:0009605 264 0.021
programmed cell death GO:0012501 119 0.020
Zebrafish
ribonucleoside monophosphate catabolic process GO:0009158 4 0.020
lipid catabolic process GO:0016042 4 0.020
regulation of sodium ion transport GO:0002028 2 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
Human Fly
cellular ketone metabolic process GO:0042180 11 0.020
oxoacid metabolic process GO:0043436 31 0.020
regulation of metal ion transport GO:0010959 4 0.020
regulation of gene expression GO:0010468 265 0.020
Human Fly
nucleocytoplasmic transport GO:0006913 4 0.019
regulation of synapse assembly GO:0051963 3 0.019
regulation of cell activation GO:0050865 1 0.019
negative regulation of signal transduction GO:0009968 94 0.019
regulation of cell projection assembly GO:0060491 4 0.019
neuroblast differentiation GO:0014016 1 0.019
axon guidance GO:0007411 86 0.019
regulation of reproductive process GO:2000241 4 0.019
positive regulation of muscle cell differentiation GO:0051149 1 0.019
regulation of endothelial cell differentiation GO:0045601 3 0.019
epithelial cell differentiation GO:0030855 116 0.018
cell morphogenesis GO:0000902 289 0.018
positive regulation of cell cycle GO:0045787 3 0.018
neuron neuron synaptic transmission GO:0007270 1 0.018
aorta morphogenesis GO:0035909 3 0.018
cellular response to nutrient levels GO:0031669 2 0.018
membrane invagination GO:0010324 1 0.018
positive regulation of gtp catabolic process GO:0033126 1 0.018
startle response GO:0001964 4 0.018
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.018
positive regulation of gene expression GO:0010628 71 0.018
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.018
Fly
cell aging GO:0007569 2 0.018
regulation of erk1 and erk2 cascade GO:0070372 4 0.018
skin development GO:0043588 54 0.018
regulation of intracellular ph GO:0051453 1 0.018
positive regulation of nucleotide catabolic process GO:0030813 1 0.018
regulation of cellular ph GO:0030641 1 0.018
regulation of filopodium assembly GO:0051489 2 0.017
regulation of cell differentiation GO:0045595 142 0.017
regulation of protein transport GO:0051223 3 0.017
rna transport GO:0050658 2 0.017
stem cell maintenance GO:0019827 4 0.017
cellular ion homeostasis GO:0006873 17 0.017
cellular localization GO:0051641 97 0.017
response to nutrient GO:0007584 3 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.017
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.017
sensory neuron axon guidance GO:0097374 3 0.017
nucleic acid transport GO:0050657 2 0.017
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.017
spermatid differentiation GO:0048515 2 0.017
ras protein signal transduction GO:0007265 7 0.017
heart morphogenesis GO:0003007 156 0.017
sensory organ morphogenesis GO:0090596 200 0.017
response to organic substance GO:0010033 153 0.017
regulation of cell development GO:0060284 100 0.017
epithelial tube morphogenesis GO:0060562 148 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
protein complex disassembly GO:0043241 1 0.016
chemotaxis GO:0006935 104 0.016
establishment of rna localization GO:0051236 3 0.016
spliceosomal complex assembly GO:0000245 1 0.016
regulation of cell communication GO:0010646 232 0.016
nucleic acid templated transcription GO:0097659 181 0.016
Human Fly
divalent inorganic cation homeostasis GO:0072507 22 0.016
eye morphogenesis GO:0048592 144 0.016
ovulation cycle process GO:0022602 2 0.016
chordate embryonic development GO:0043009 271 0.016
apoptotic process GO:0006915 116 0.016
Zebrafish
camera type eye development GO:0043010 222 0.016
cellular response to external stimulus GO:0071496 2 0.016
positive regulation of ras protein signal transduction GO:0046579 1 0.015
nuclear transport GO:0051169 4 0.015
determination of bilateral symmetry GO:0009855 204 0.015
head development GO:0060322 303 0.015
negative regulation of cell motility GO:2000146 17 0.015
positive regulation of map kinase activity GO:0043406 3 0.015
response to lipid GO:0033993 60 0.015
neuronal stem cell maintenance GO:0097150 2 0.015
regulation of cellular component organization GO:0051128 86 0.015
negative regulation of macromolecule metabolic process GO:0010605 76 0.015
Human
somitogenesis GO:0001756 87 0.015
protein targeting to nucleus GO:0044744 3 0.015
regulation of fatty acid metabolic process GO:0019217 1 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
immune system development GO:0002520 191 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
forebrain regionalization GO:0021871 4 0.014
protein polymerization GO:0051258 4 0.014
single organism metabolic process GO:0044710 217 0.014
Human Fly
tissue remodeling GO:0048771 4 0.014
axon development GO:0061564 166 0.014
nuclear import GO:0051170 3 0.014
positive regulation of cellular component biogenesis GO:0044089 3 0.014
organic acid metabolic process GO:0006082 31 0.014
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.014
single organism localization GO:1902578 225 0.014
regulation of muscle contraction GO:0006937 3 0.014
muscle cell fate determination GO:0007521 1 0.014
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
nuclear export GO:0051168 1 0.014
regulation of dendrite development GO:0050773 3 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
cell projection morphogenesis GO:0048858 244 0.014
negative regulation of metabolic process GO:0009892 86 0.014
Human
negative regulation of response to cytokine stimulus GO:0060761 2 0.014
cell matrix adhesion GO:0007160 4 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
gtp catabolic process GO:0006184 2 0.013
neuron projection development GO:0031175 180 0.013
regulation of response to cytokine stimulus GO:0060759 3 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
endothelial cell fate commitment GO:0060839 3 0.013
retina development in camera type eye GO:0060041 146 0.013
positive regulation of secretion GO:0051047 1 0.013
ovulation cycle GO:0042698 2 0.013
skeletal system morphogenesis GO:0048705 102 0.013
protein import into nucleus GO:0006606 3 0.013
regulation of molecular function GO:0065009 70 0.013
cellular cation homeostasis GO:0030003 17 0.013
negative regulation of cellular biosynthetic process GO:0031327 55 0.013
Human
positive regulation of cell adhesion GO:0045785 1 0.013
regulation of binding GO:0051098 3 0.013
regulation of protein metabolic process GO:0051246 56 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
phagocytosis engulfment GO:0006911 1 0.013
vasculature development GO:0001944 278 0.013
protein dephosphorylation GO:0006470 3 0.013
negative regulation of kinase activity GO:0033673 4 0.013
regulation of hormone secretion GO:0046883 2 0.013
response to wounding GO:0009611 116 0.013
cellular response to growth factor stimulus GO:0071363 39 0.013
regulation of cell substrate adhesion GO:0010810 1 0.013
positive regulation of translation GO:0045727 1 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
protein localization to nucleus GO:0034504 3 0.012
protein import GO:0017038 3 0.012
protein secretion GO:0009306 1 0.012
intracellular signal transduction GO:0035556 85 0.012
regulation of synapse organization GO:0050807 3 0.012
protein demethylation GO:0006482 2 0.012
Human Fly
macromolecular complex disassembly GO:0032984 1 0.012
somatic muscle development GO:0007525 4 0.012
small molecule metabolic process GO:0044281 77 0.012
calcium ion transport into cytosol GO:0060402 3 0.012
phosphorus metabolic process GO:0006793 109 0.012
cellular component biogenesis GO:0044085 178 0.012
establishment or maintenance of cell polarity GO:0007163 29 0.012
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.012
negative regulation of cytokine production GO:0001818 1 0.012
tube morphogenesis GO:0035239 349 0.012
regulation of cell death GO:0010941 103 0.012
Zebrafish
regulation of intracellular protein transport GO:0033157 3 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
somite development GO:0061053 96 0.012
regulation of catalytic activity GO:0050790 55 0.012
renal system development GO:0072001 94 0.012
calcium ion homeostasis GO:0055074 19 0.012
axon regeneration GO:0031103 14 0.012
specification of symmetry GO:0009799 204 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
fertilization GO:0009566 3 0.012
cell morphogenesis involved in differentiation GO:0000904 195 0.012
gtp metabolic process GO:0046039 4 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
regulation of cytokine production GO:0001817 3 0.012
negative regulation of locomotion GO:0040013 18 0.012
zymogen activation GO:0031638 3 0.012
lymph vessel morphogenesis GO:0036303 25 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.011
regulation of response to nutrient levels GO:0032107 1 0.011
sleep GO:0030431 1 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
protein targeting to membrane GO:0006612 1 0.011
intracellular estrogen receptor signaling pathway GO:0030520 3 0.011
sequestering of calcium ion GO:0051208 3 0.011
negative regulation of rna metabolic process GO:0051253 48 0.011
Human
heart looping GO:0001947 94 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.011
action potential GO:0001508 19 0.011
skeletal muscle organ development GO:0060538 78 0.011
male meiosis GO:0007140 2 0.011
regulation of autophagy GO:0010506 3 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
cell migration involved in heart development GO:0060973 22 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
limb bud formation GO:0060174 2 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
atp catabolic process GO:0006200 4 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.011
Human
determination of left right symmetry GO:0007368 179 0.011
cytoplasm organization GO:0007028 4 0.011
cell fate commitment GO:0045165 99 0.011
establishment of protein localization to organelle GO:0072594 4 0.011
lipid metabolic process GO:0006629 52 0.011
neurotransmitter secretion GO:0007269 2 0.011
regulation of gtpase activity GO:0043087 2 0.011
regulation of mrna processing GO:0050684 3 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
Fly
sequestering of metal ion GO:0051238 3 0.011
regulation of cell morphogenesis GO:0022604 42 0.011
establishment of localization in cell GO:0051649 77 0.011
cellular response to radiation GO:0071478 4 0.011
protein polyubiquitination GO:0000209 4 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
actin polymerization or depolymerization GO:0008154 2 0.010
negative regulation of ras protein signal transduction GO:0046580 1 0.010
positive regulation of signal transduction GO:0009967 56 0.010
regulation of cellular component movement GO:0051270 55 0.010
mononuclear cell proliferation GO:0032943 1 0.010
response to abiotic stimulus GO:0009628 122 0.010
heart valve formation GO:0003188 4 0.010
amine metabolic process GO:0009308 2 0.010
notochord development GO:0030903 54 0.010
regulation of jak stat cascade GO:0046425 3 0.010
lymphatic endothelial cell fate commitment GO:0060838 1 0.010
single fertilization GO:0007338 3 0.010
activation of mapk activity GO:0000187 3 0.010
regulation of nucleoside metabolic process GO:0009118 2 0.010
locomotor rhythm GO:0045475 3 0.010
Fly
negative regulation of multi organism process GO:0043901 3 0.010

kdm5bb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018