Danio rerio

0 known processes

im:7145476

im:7145476

im:7145476 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.069
maintenance of location GO:0051235 4 0.043
establishment of protein localization to organelle GO:0072594 4 0.042
modification dependent protein catabolic process GO:0019941 3 0.037
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.037
signal transduction GO:0007165 455 0.036
positive regulation of transport GO:0051050 2 0.035
ubiquitin dependent protein catabolic process GO:0006511 3 0.035
cellular protein catabolic process GO:0044257 4 0.033
positive regulation of catabolic process GO:0009896 4 0.033
regulation of establishment of protein localization GO:0070201 4 0.032
aging GO:0007568 2 0.032
cell surface receptor signaling pathway GO:0007166 325 0.031
regulation of protein catabolic process GO:0042176 1 0.030
positive regulation of cellular catabolic process GO:0031331 3 0.030
modification dependent macromolecule catabolic process GO:0043632 3 0.030
multicellular organism growth GO:0035264 4 0.029
amine metabolic process GO:0009308 2 0.029
cellular amine metabolic process GO:0044106 2 0.029
stem cell maintenance GO:0019827 4 0.028
tube morphogenesis GO:0035239 349 0.027
cellular macromolecule metabolic process GO:0044260 391 0.026
nuclear transport GO:0051169 4 0.026
regulation of protein transport GO:0051223 3 0.026
cognition GO:0050890 1 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.025
phagocytosis GO:0006909 3 0.025
meiotic cell cycle process GO:1903046 3 0.025
positive regulation of cell cycle GO:0045787 3 0.024
response to chemical GO:0042221 320 0.024
protein secretion GO:0009306 1 0.024
nitrogen compound metabolic process GO:0006807 319 0.024
regulation of multicellular organism growth GO:0040014 4 0.024
cellular nitrogen compound metabolic process GO:0034641 290 0.024
regulation of metabolic process GO:0019222 359 0.023
response to drug GO:0042493 3 0.023
meiotic nuclear division GO:0007126 4 0.023
rna metabolic process GO:0016070 219 0.022
regulation of binding GO:0051098 3 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
protein localization to nucleus GO:0034504 3 0.022
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.022
cellular component morphogenesis GO:0032989 336 0.022
cell migration GO:0016477 237 0.022
digestive tract morphogenesis GO:0048546 231 0.022
heterocycle metabolic process GO:0046483 290 0.022
cellular response to biotic stimulus GO:0071216 3 0.021
lipid storage GO:0019915 1 0.021
nucleocytoplasmic transport GO:0006913 4 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
negative regulation of biological process GO:0048519 304 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
nuclear import GO:0051170 3 0.021
digestive system development GO:0055123 289 0.021
response to stress GO:0006950 263 0.021
sensory organ development GO:0007423 393 0.021
cell morphogenesis GO:0000902 289 0.021
regulation of signal transduction GO:0009966 225 0.021
nucleobase containing compound metabolic process GO:0006139 274 0.021
transport GO:0006810 220 0.021
establishment of localization GO:0051234 244 0.021
organic cyclic compound metabolic process GO:1901360 301 0.021
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.021
regulation of signaling GO:0023051 235 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
nucleic acid templated transcription GO:0097659 181 0.020
central nervous system development GO:0007417 387 0.020
cellular biosynthetic process GO:0044249 286 0.020
system process GO:0003008 185 0.020
regulation of protein complex assembly GO:0043254 3 0.020
mitochondrion organization GO:0007005 4 0.020
gastrulation GO:0007369 208 0.020
locomotion GO:0040011 313 0.020
hemopoiesis GO:0030097 183 0.020
regulation of cellular metabolic process GO:0031323 320 0.020
protein localization to plasma membrane GO:0072659 1 0.020
regulation of biological quality GO:0065008 263 0.020
golgi vesicle transport GO:0048193 3 0.020
protein import GO:0017038 3 0.020
regulation of cytokine production GO:0001817 3 0.020
aromatic compound biosynthetic process GO:0019438 217 0.019
regulation of cell activation GO:0050865 1 0.019
camera type eye development GO:0043010 222 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
peptidyl lysine acetylation GO:0018394 2 0.019
cellular response to external stimulus GO:0071496 2 0.019
gtp catabolic process GO:0006184 2 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
immune system process GO:0002376 241 0.019
regionalization GO:0003002 274 0.019
eye development GO:0001654 277 0.019
cytokinesis GO:0000910 3 0.019
cellular amide metabolic process GO:0043603 4 0.019
generation of neurons GO:0048699 385 0.019
gtp metabolic process GO:0046039 4 0.019
autophagy GO:0006914 4 0.019
internal protein amino acid acetylation GO:0006475 2 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
cell projection organization GO:0030030 284 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
single organism nuclear import GO:1902593 3 0.019
regulation of developmental process GO:0050793 247 0.018
negative regulation of cellular process GO:0048523 283 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
single organism metabolic process GO:0044710 217 0.018
neuron differentiation GO:0030182 353 0.018
cellular component movement GO:0006928 335 0.018
cellular macromolecule biosynthetic process GO:0034645 224 0.018
regulation of reproductive process GO:2000241 4 0.018
response to external stimulus GO:0009605 264 0.018
regulation of mrna processing GO:0050684 3 0.018
regulation of meiotic cell cycle GO:0051445 1 0.018
regulation of response to stimulus GO:0048583 269 0.018
transcription dna templated GO:0006351 181 0.018
protein acylation GO:0043543 3 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
biosynthetic process GO:0009058 294 0.018
regulation of cell communication GO:0010646 232 0.018
nucleic acid metabolic process GO:0090304 244 0.018
regulation of synaptic plasticity GO:0048167 1 0.017
gene expression GO:0010467 252 0.017
cellular aromatic compound metabolic process GO:0006725 295 0.017
regulation of primary metabolic process GO:0080090 311 0.017
cell part morphogenesis GO:0032990 246 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
cellular response to molecule of bacterial origin GO:0071219 3 0.017
regulation of gene expression GO:0010468 265 0.017
protein acetylation GO:0006473 2 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
regulation of protein ubiquitination GO:0031396 3 0.017
embryonic organ development GO:0048568 381 0.017
nucleobase containing compound biosynthetic process GO:0034654 205 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
digestive tract development GO:0048565 265 0.017
compound eye development GO:0048749 2 0.017
protein import into nucleus GO:0006606 3 0.017
protein targeting to nucleus GO:0044744 3 0.017
blood vessel development GO:0001568 246 0.017
positive regulation of cell activation GO:0050867 1 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
morphogenesis of an epithelium GO:0002009 333 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
organelle organization GO:0006996 227 0.017
growth GO:0040007 174 0.016
internal peptidyl lysine acetylation GO:0018393 2 0.016
regulation of biosynthetic process GO:0009889 250 0.016
regulation of reactive oxygen species metabolic process GO:2000377 2 0.016
adult behavior GO:0030534 2 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
muscle structure development GO:0061061 196 0.016
rna biosynthetic process GO:0032774 181 0.016
organic acid metabolic process GO:0006082 31 0.016
positive regulation of cellular process GO:0048522 201 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
single organism organelle organization GO:1902589 199 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
phagocytosis engulfment GO:0006911 1 0.016
positive regulation of leukocyte differentiation GO:1902107 1 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
positive regulation of cytokine production GO:0001819 2 0.016
localization of cell GO:0051674 244 0.016
head development GO:0060322 303 0.016
single organism localization GO:1902578 225 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
regulation of cellular biosynthetic process GO:0031326 245 0.016
positive regulation of biological process GO:0048518 253 0.016
positive regulation of map kinase activity GO:0043406 3 0.016
regulation of mrna splicing via spliceosome GO:0048024 3 0.016
immune system development GO:0002520 191 0.015
brain development GO:0007420 293 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
protein polymerization GO:0051258 4 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
neuron development GO:0048666 262 0.015
cellular ketone metabolic process GO:0042180 11 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
cellular response to nutrient levels GO:0031669 2 0.015
membrane invagination GO:0010324 1 0.015
centrosome organization GO:0051297 1 0.015
response to uv GO:0009411 3 0.015
positive regulation of dna metabolic process GO:0051054 1 0.015
regulation of cell shape GO:0008360 1 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
cell projection morphogenesis GO:0048858 244 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
translational initiation GO:0006413 3 0.015
peptide transport GO:0015833 1 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
leukocyte proliferation GO:0070661 1 0.015
carbohydrate homeostasis GO:0033500 1 0.015
development of primary female sexual characteristics GO:0046545 4 0.014
positive regulation of immune effector process GO:0002699 3 0.014
cellular component disassembly GO:0022411 1 0.014
spermatid differentiation GO:0048515 2 0.014
protein metabolic process GO:0019538 183 0.014
stem cell proliferation GO:0072089 4 0.014
cellular component assembly GO:0022607 170 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
specification of symmetry GO:0009799 204 0.014
b cell activation GO:0042113 2 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
cellular component biogenesis GO:0044085 178 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
negative regulation of catabolic process GO:0009895 3 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
female sex differentiation GO:0046660 4 0.014
organic substance biosynthetic process GO:1901576 289 0.014
regulation of rna metabolic process GO:0051252 224 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
response to organic substance GO:0010033 153 0.014
endosomal transport GO:0016197 2 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
protein stabilization GO:0050821 2 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.013
cell motility GO:0048870 244 0.013
positive regulation of secretion GO:0051047 1 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
cellular response to starvation GO:0009267 1 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
calcium ion transport into cytosol GO:0060402 3 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
regulation of protein targeting GO:1903533 2 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
cellular response to radiation GO:0071478 4 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
female gonad development GO:0008585 4 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
tissue remodeling GO:0048771 4 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
vasculature development GO:0001944 278 0.013
chemosensory behavior GO:0007635 1 0.013
glucose homeostasis GO:0042593 1 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
regulation of metal ion transport GO:0010959 4 0.013
ameboidal type cell migration GO:0001667 143 0.013
cell death GO:0008219 121 0.013
regulation of jak stat cascade GO:0046425 3 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
cellular protein metabolic process GO:0044267 129 0.013
response to hexose GO:0009746 3 0.013
response to topologically incorrect protein GO:0035966 2 0.013
regulation of inflammatory response GO:0050727 2 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
regulation of transcription dna templated GO:0006355 213 0.013
single organism transport GO:0044765 206 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
response to alkaloid GO:0043279 2 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
regulation of protein polymerization GO:0032271 2 0.012
actin filament polymerization GO:0030041 2 0.012
regulation of cell death GO:0010941 103 0.012
response to carbohydrate GO:0009743 3 0.012
locomotor rhythm GO:0045475 3 0.012
negative regulation of defense response GO:0031348 2 0.012
spermatid development GO:0007286 2 0.012
meiotic chromosome segregation GO:0045132 3 0.012
negative regulation of nuclear division GO:0051784 3 0.012
synaptic vesicle localization GO:0097479 1 0.012
transmembrane transport GO:0055085 120 0.012
regulation of gtpase activity GO:0043087 2 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
negative regulation of kinase activity GO:0033673 4 0.012
determination of bilateral symmetry GO:0009855 204 0.012
antimicrobial humoral response GO:0019730 2 0.012
germ line stem cell maintenance GO:0030718 2 0.012
homeostatic process GO:0042592 142 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
cytokinetic process GO:0032506 2 0.012
cytoplasm organization GO:0007028 4 0.012
heart development GO:0007507 313 0.012
stem cell division GO:0017145 1 0.012
sequestering of metal ion GO:0051238 3 0.012
positive regulation of translation GO:0045727 1 0.012
interspecies interaction between organisms GO:0044419 4 0.012
response to nutrient GO:0007584 3 0.012
dicarboxylic acid transport GO:0006835 1 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
chordate embryonic development GO:0043009 271 0.012
regulation of synapse organization GO:0050807 3 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
exocytosis GO:0006887 1 0.012
lymphocyte proliferation GO:0046651 1 0.012
cellular response to organic substance GO:0071310 105 0.012
post embryonic organ development GO:0048569 4 0.012
angiogenesis GO:0001525 158 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
peptidyl serine modification GO:0018209 2 0.012
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.012
regulation of muscle contraction GO:0006937 3 0.011
microtubule organizing center organization GO:0031023 1 0.011
epithelial tube morphogenesis GO:0060562 148 0.011
regulation of wound healing GO:0061041 2 0.011
neuroblast proliferation GO:0007405 2 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
response to monosaccharide GO:0034284 3 0.011
small molecule metabolic process GO:0044281 77 0.011
neuron projection development GO:0031175 180 0.011
oxoacid metabolic process GO:0043436 31 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
membrane fusion GO:0061025 2 0.011
developmental growth GO:0048589 166 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
gland development GO:0048732 143 0.011
regulation of synapse assembly GO:0051963 3 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
macromolecule modification GO:0043412 111 0.011
somatic muscle development GO:0007525 4 0.011
adherens junction organization GO:0034332 4 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
protein complex disassembly GO:0043241 1 0.011
secondary metabolic process GO:0019748 3 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
regulation of blood pressure GO:0008217 1 0.011
atp catabolic process GO:0006200 4 0.011
protein heterooligomerization GO:0051291 1 0.011
regulation of cell projection assembly GO:0060491 4 0.011
macromolecular complex disassembly GO:0032984 1 0.011
negative regulation of sequestering of calcium ion GO:0051283 4 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
rna localization GO:0006403 4 0.011
regulation of production of molecular mediator of immune response GO:0002700 1 0.011
hormone transport GO:0009914 2 0.011
regulation of tube size GO:0035150 2 0.011
protein polyubiquitination GO:0000209 4 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
apoptotic process GO:0006915 116 0.011
death GO:0016265 121 0.011
lipid homeostasis GO:0055088 3 0.011
positive regulation of chromosome organization GO:2001252 1 0.010
convergent extension GO:0060026 118 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
hormone secretion GO:0046879 2 0.010
sequestering of calcium ion GO:0051208 3 0.010
meiosis i GO:0007127 1 0.010
segmentation GO:0035282 97 0.010
negative regulation of protein transport GO:0051224 3 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
alternative mrna splicing via spliceosome GO:0000380 1 0.010
nuclear export GO:0051168 1 0.010
erk1 and erk2 cascade GO:0070371 4 0.010
negative regulation of multi organism process GO:0043901 3 0.010
response to glucose GO:0009749 3 0.010
spindle assembly GO:0051225 2 0.010
cell migration involved in gastrulation GO:0042074 79 0.010
ion transmembrane transport GO:0034220 91 0.010
cellular response to light stimulus GO:0071482 4 0.010
regulation of autophagy GO:0010506 3 0.010
mononuclear cell proliferation GO:0032943 1 0.010
regulation of calcium ion transport GO:0051924 2 0.010
cellular protein modification process GO:0006464 100 0.010
muscle cell development GO:0055001 115 0.010
peptide metabolic process GO:0006518 1 0.010
protein modification process GO:0036211 100 0.010
regulation of cell differentiation GO:0045595 142 0.010
positive regulation of gtp catabolic process GO:0033126 1 0.010
positive regulation of notch signaling pathway GO:0045747 3 0.010
maternal determination of anterior posterior axis embryo GO:0008358 4 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.010

im:7145476 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.021
disease of metabolism DOID:0014667 0 0.016
musculoskeletal system disease DOID:17 0 0.015
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.013
inherited metabolic disorder DOID:655 0 0.011
muscular disease DOID:0080000 0 0.010