Danio rerio

0 known processes

eif4e1b

eukaryotic translation initiation factor 4e 1b

(Aliases: eif4e,zeIF4E,Z4ES)

eif4e1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule metabolic process GO:0044260 391 0.674
Worm Fly
regulation of primary metabolic process GO:0080090 311 0.660
Worm
positive regulation of cellular process GO:0048522 201 0.592
Worm
regionalization GO:0003002 274 0.588
regulation of biological quality GO:0065008 263 0.487
Worm
regulation of multicellular organismal process GO:0051239 277 0.441
negative regulation of biological process GO:0048519 304 0.383
cellular biosynthetic process GO:0044249 286 0.382
Worm Fly
positive regulation of biological process GO:0048518 253 0.352
Worm
specification of symmetry GO:0009799 204 0.328
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.327
regulation of metabolic process GO:0019222 359 0.305
Worm
negative regulation of cellular process GO:0048523 283 0.301
nitrogen compound metabolic process GO:0006807 319 0.299
Fly
signal transduction GO:0007165 455 0.295
organic substance biosynthetic process GO:1901576 289 0.281
Worm Fly
regulation of cellular metabolic process GO:0031323 320 0.246
Worm
regulation of response to stimulus GO:0048583 269 0.244
organic cyclic compound metabolic process GO:1901360 301 0.238
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.236
Worm
cellular macromolecule biosynthetic process GO:0034645 224 0.224
Worm Fly
tube morphogenesis GO:0035239 349 0.211
nucleobase containing compound metabolic process GO:0006139 274 0.208
Fly
response to chemical GO:0042221 320 0.203
single fertilization GO:0007338 3 0.195
determination of bilateral symmetry GO:0009855 204 0.193
regulation of reproductive process GO:2000241 4 0.188
regulation of macromolecule metabolic process GO:0060255 317 0.188
Worm
nucleic acid templated transcription GO:0097659 181 0.184
macromolecule modification GO:0043412 111 0.182
immune system process GO:0002376 241 0.173
gastrulation GO:0007369 208 0.170
embryonic heart tube development GO:0035050 133 0.165
oocyte maturation GO:0001556 4 0.162
Worm
regulation of gene expression GO:0010468 265 0.162
Worm
cellular component morphogenesis GO:0032989 336 0.158
digestive tract morphogenesis GO:0048546 231 0.157
organic cyclic compound biosynthetic process GO:1901362 223 0.156
nucleic acid metabolic process GO:0090304 244 0.155
Fly
regulation of cellular protein metabolic process GO:0032268 52 0.149
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.147
cellular protein metabolic process GO:0044267 129 0.144
Worm Fly
determination of heart left right asymmetry GO:0061371 117 0.144
blood vessel development GO:0001568 246 0.141
regulation of signal transduction GO:0009966 225 0.139
biosynthetic process GO:0009058 294 0.139
Worm Fly
modification dependent protein catabolic process GO:0019941 3 0.139
cell motility GO:0048870 244 0.136
single organism localization GO:1902578 225 0.133
digestive tract development GO:0048565 265 0.132
heart looping GO:0001947 94 0.130
response to organic substance GO:0010033 153 0.130
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.126
heterocycle biosynthetic process GO:0018130 215 0.124
larval development GO:0002164 2 0.122
nucleobase containing compound biosynthetic process GO:0034654 205 0.121
vasculature development GO:0001944 278 0.120
cell projection morphogenesis GO:0048858 244 0.120
determination of left right symmetry GO:0007368 179 0.119
morphogenesis of an epithelium GO:0002009 333 0.118
locomotion GO:0040011 313 0.115
positive regulation of transport GO:0051050 2 0.113
regulation of nitrogen compound metabolic process GO:0051171 251 0.113
single organism organelle organization GO:1902589 199 0.113
Fly
regulation of protein metabolic process GO:0051246 56 0.112
Worm
establishment of localization GO:0051234 244 0.111
anterior posterior pattern specification GO:0009952 152 0.111
growth GO:0040007 174 0.111
Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.111
negative regulation of reproductive process GO:2000242 3 0.109
cellular protein modification process GO:0006464 100 0.104
segmentation GO:0035282 97 0.101
heterocycle metabolic process GO:0046483 290 0.100
Fly
immune response GO:0006955 28 0.097
cellular nitrogen compound metabolic process GO:0034641 290 0.094
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.094
Fly
protein modification process GO:0036211 100 0.093
gene expression GO:0010467 252 0.092
Worm Fly
defense response GO:0006952 47 0.092
protein complex subunit organization GO:0071822 46 0.089
Fly
rna biosynthetic process GO:0032774 181 0.088
regulation of rna metabolic process GO:0051252 224 0.088
multi organism reproductive process GO:0044703 36 0.088
Worm
protein metabolic process GO:0019538 183 0.087
Worm Fly
multi organism process GO:0051704 134 0.086
Worm
regulation of nucleic acid templated transcription GO:1903506 213 0.086
neuron differentiation GO:0030182 353 0.084
single organism transport GO:0044765 206 0.083
maintenance of location GO:0051235 4 0.083
Worm
brain development GO:0007420 293 0.080
endoderm development GO:0007492 49 0.079
mesoderm development GO:0007498 88 0.078
blood vessel morphogenesis GO:0048514 216 0.077
bmp signaling pathway GO:0030509 52 0.076
cell cell recognition GO:0009988 1 0.075
regulation of macromolecule biosynthetic process GO:0010556 225 0.075
Worm
chromosome organization GO:0051276 31 0.074
Fly
heart morphogenesis GO:0003007 156 0.074
regulation of multicellular organismal development GO:2000026 223 0.073
cellular nitrogen compound biosynthetic process GO:0044271 218 0.072
cell morphogenesis involved in differentiation GO:0000904 195 0.072
aromatic compound biosynthetic process GO:0019438 217 0.071
regulation of biosynthetic process GO:0009889 250 0.068
Worm
heart development GO:0007507 313 0.067
central nervous system development GO:0007417 387 0.066
sister chromatid segregation GO:0000819 6 0.066
Fly
cell morphogenesis GO:0000902 289 0.065
hemopoiesis GO:0030097 183 0.065
regulation of transcription dna templated GO:0006355 213 0.063
cell surface receptor signaling pathway GO:0007166 325 0.061
embryonic organ development GO:0048568 381 0.061
single organism metabolic process GO:0044710 217 0.060
Fly
muscle cell development GO:0055001 115 0.059
development of primary female sexual characteristics GO:0046545 4 0.059
neuron projection development GO:0031175 180 0.058
endoderm formation GO:0001706 29 0.057
digestive system development GO:0055123 289 0.057
positive regulation of cell cycle GO:0045787 3 0.057
developmental growth GO:0048589 166 0.057
regulation of cellular biosynthetic process GO:0031326 245 0.057
Worm
determination of dorsal ventral asymmetry GO:0048262 34 0.056
centrosome organization GO:0051297 1 0.055
regulation of localization GO:0032879 104 0.055
macromolecule biosynthetic process GO:0009059 227 0.054
Worm Fly
intracellular signal transduction GO:0035556 85 0.054
regulation of cell differentiation GO:0045595 142 0.053
positive regulation of response to stimulus GO:0048584 80 0.053
ubiquitin dependent protein catabolic process GO:0006511 3 0.052
organelle assembly GO:0070925 110 0.052
transcription dna templated GO:0006351 181 0.052
aging GO:0007568 2 0.051
Worm
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.050
formation of primary germ layer GO:0001704 62 0.050
cellular protein catabolic process GO:0044257 4 0.049
epithelial tube morphogenesis GO:0060562 148 0.049
cell death GO:0008219 121 0.049
Fly
oocyte development GO:0048599 14 0.047
Worm
axon development GO:0061564 166 0.047
positive regulation of macromolecule metabolic process GO:0010604 93 0.046
Worm
positive regulation of cellular metabolic process GO:0031325 94 0.045
Worm
cellular response to chemical stimulus GO:0070887 157 0.045
neuron development GO:0048666 262 0.044
protein phosphorylation GO:0006468 47 0.044
cell projection organization GO:0030030 284 0.043
spemann organizer formation GO:0060061 10 0.043
ion transport GO:0006811 114 0.042
regulation of cellular component organization GO:0051128 86 0.042
Fly
embryonic heart tube morphogenesis GO:0003143 108 0.042
positive regulation of cytokine production GO:0001819 2 0.042
regulation of developmental process GO:0050793 247 0.041
organelle organization GO:0006996 227 0.041
Worm Fly
regulation of rna biosynthetic process GO:2001141 213 0.041
fertilization GO:0009566 3 0.040
somitogenesis GO:0001756 87 0.039
cellular component assembly GO:0022607 170 0.039
multicellular organism reproduction GO:0032504 35 0.038
Worm
ion transmembrane transport GO:0034220 91 0.038
cell migration GO:0016477 237 0.038
stem cell proliferation GO:0072089 4 0.038
inorganic ion transmembrane transport GO:0098660 57 0.038
positive regulation of metabolic process GO:0009893 108 0.037
Worm
generation of neurons GO:0048699 385 0.037
immune system development GO:0002520 191 0.037
head development GO:0060322 303 0.036
inorganic cation transmembrane transport GO:0098662 50 0.035
phosphorus metabolic process GO:0006793 109 0.035
regulation of signaling GO:0023051 235 0.035
cellular component movement GO:0006928 335 0.034
meiotic chromosome segregation GO:0045132 3 0.033
Worm Fly
embryonic pattern specification GO:0009880 44 0.033
cellular localization GO:0051641 97 0.032
single organism reproductive process GO:0044702 40 0.032
Worm
cellular component biogenesis GO:0044085 178 0.032
proteasomal protein catabolic process GO:0010498 2 0.031
phosphorylation GO:0016310 69 0.031
positive regulation of rna biosynthetic process GO:1902680 57 0.031
oxoacid metabolic process GO:0043436 31 0.030
transcription from rna polymerase ii promoter GO:0006366 80 0.030
rna metabolic process GO:0016070 219 0.030
Fly
regulation of anatomical structure morphogenesis GO:0022603 130 0.030
spemann organizer formation at the embryonic shield GO:0060063 2 0.029
regulation of gastrulation GO:0010470 24 0.029
morphogenesis of an epithelial sheet GO:0002011 49 0.029
striated muscle cell differentiation GO:0051146 129 0.029
protein complex assembly GO:0006461 30 0.028
endodermal cell differentiation GO:0035987 19 0.028
specification of organ position GO:0010159 3 0.028
response to carbohydrate GO:0009743 3 0.028
sexual reproduction GO:0019953 36 0.028
Worm
specification of organ identity GO:0010092 2 0.028
negative regulation of cellular metabolic process GO:0031324 77 0.028
oocyte differentiation GO:0009994 14 0.028
Worm
neuron projection morphogenesis GO:0048812 161 0.028
enzyme linked receptor protein signaling pathway GO:0007167 106 0.027
negative regulation of signal transduction GO:0009968 94 0.027
organonitrogen compound metabolic process GO:1901564 74 0.027
homeostatic process GO:0042592 142 0.027
regulation of endodermal cell differentiation GO:1903224 15 0.027
protein complex biogenesis GO:0070271 30 0.027
mitotic sister chromatid segregation GO:0000070 6 0.026
Fly
positive regulation of developmental process GO:0051094 50 0.026
programmed cell death GO:0012501 119 0.026
Fly
regulation of cell development GO:0060284 100 0.026
regulation of bmp signaling pathway GO:0030510 39 0.025
embryonic organ morphogenesis GO:0048562 274 0.025
axonogenesis GO:0007409 152 0.025
microtubule based process GO:0007017 60 0.025
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.025
phosphate containing compound metabolic process GO:0006796 108 0.025
apoptotic process GO:0006915 116 0.025
mitotic cell cycle embryonic GO:0045448 2 0.024
developmental growth involved in morphogenesis GO:0060560 86 0.024
oogenesis GO:0048477 14 0.024
Worm
transmembrane transport GO:0055085 120 0.023
positive regulation of muscle organ development GO:0048636 1 0.023
angiogenesis GO:0001525 158 0.023
positive regulation of signaling GO:0023056 56 0.023
dorsal ventral pattern formation GO:0009953 125 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.023
response to stress GO:0006950 263 0.023
Worm
negative regulation of cell differentiation GO:0045596 46 0.023
negative regulation of cell communication GO:0010648 96 0.023
positive regulation of cellular biosynthetic process GO:0031328 68 0.023
Worm
establishment of localization in cell GO:0051649 77 0.022
regulation of growth GO:0040008 42 0.022
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.022
Worm
regulation of cell communication GO:0010646 232 0.022
vesicle mediated transport GO:0016192 22 0.022
negative regulation of macromolecule metabolic process GO:0010605 76 0.021
positive regulation of multicellular organismal process GO:0051240 52 0.021
somite development GO:0061053 96 0.021
regulation of cell cycle GO:0051726 52 0.021
cellular response to organic substance GO:0071310 105 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.021
regulation of metal ion transport GO:0010959 4 0.021
negative regulation of cytokine production GO:0001818 1 0.021
leukocyte proliferation GO:0070661 1 0.021
cell part morphogenesis GO:0032990 246 0.021
negative regulation of response to stimulus GO:0048585 104 0.021
cardiac conduction system development GO:0003161 1 0.020
cell maturation GO:0048469 23 0.020
Worm
negative regulation of endodermal cell differentiation GO:1903225 8 0.020
regulation of transmembrane transporter activity GO:0022898 2 0.020
negative regulation of signaling GO:0023057 96 0.020
regulation of circadian rhythm GO:0042752 4 0.020
regulation of phosphorus metabolic process GO:0051174 43 0.020
neuroblast proliferation GO:0007405 2 0.020
positive regulation of transcription dna templated GO:0045893 57 0.020
chemotaxis GO:0006935 104 0.020
positive regulation of reproductive process GO:2000243 2 0.020
cation transport GO:0006812 81 0.020
regulation of cytokine production GO:0001817 3 0.019
cytoskeleton organization GO:0007010 96 0.019
Fly
heart field specification GO:0003128 1 0.019
regulation of calcium ion dependent exocytosis GO:0017158 1 0.019
outflow tract morphogenesis GO:0003151 1 0.019
mesoderm formation GO:0001707 43 0.019
muscle cell differentiation GO:0042692 139 0.019
response to external stimulus GO:0009605 264 0.019
regulation of oocyte development GO:0060281 3 0.019
regulation of immune system process GO:0002682 34 0.019
regulation of protein modification process GO:0031399 29 0.018
actin cytoskeleton organization GO:0030036 63 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.018
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.018
Worm
regulation of gene expression epigenetic GO:0040029 11 0.018
stem cell maintenance GO:0019827 4 0.018
regulation of protein complex assembly GO:0043254 3 0.018
embryonic hemopoiesis GO:0035162 53 0.018
positive regulation of cell communication GO:0010647 56 0.018
spindle assembly GO:0051225 2 0.018
positive regulation of gene expression GO:0010628 71 0.018
Worm
hepaticobiliary system development GO:0061008 98 0.018
positive regulation of multi organism process GO:0043902 3 0.018
regulation of programmed cell death GO:0043067 101 0.018
embryonic digestive tract development GO:0048566 4 0.018
macromolecular complex subunit organization GO:0043933 74 0.017
Fly
determination of ventral identity GO:0048264 21 0.017
death GO:0016265 121 0.017
Fly
cation transmembrane transport GO:0098655 65 0.017
sensory organ development GO:0007423 393 0.017
regulation of cell activation GO:0050865 1 0.017
regulation of molecular function GO:0065009 70 0.017
positive regulation of biosynthetic process GO:0009891 68 0.017
Worm
striated muscle cell development GO:0055002 108 0.017
negative regulation of mitosis GO:0045839 3 0.017
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.017
localization of cell GO:0051674 244 0.017
muscle structure development GO:0061061 196 0.017
regulation of mrna processing GO:0050684 3 0.017
organic acid metabolic process GO:0006082 31 0.016
negative regulation of endodermal cell fate specification GO:0042664 8 0.016
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.016
phagocytosis GO:0006909 3 0.016
neuron projection extension GO:1990138 45 0.016
regulation of skeletal muscle tissue development GO:0048641 4 0.016
oocyte anterior posterior axis specification GO:0007314 4 0.016
gastrulation with mouth forming second GO:0001702 44 0.016
ear development GO:0043583 127 0.016
meiotic cell cycle process GO:1903046 3 0.016
Worm Fly
cell fate commitment GO:0045165 99 0.015
positive regulation of molecular function GO:0044093 33 0.015
actin filament based process GO:0030029 64 0.015
negative regulation of multi organism process GO:0043901 3 0.015
macromolecular complex assembly GO:0065003 35 0.015
liver development GO:0001889 96 0.015
positive regulation of immune system process GO:0002684 17 0.015
dorsal ventral axis specification GO:0009950 14 0.015
regulation of tube size GO:0035150 2 0.015
regulation of ph GO:0006885 3 0.015
transport GO:0006810 220 0.014
small molecule metabolic process GO:0044281 77 0.014
muscle tissue development GO:0060537 110 0.014
skeletal system development GO:0001501 181 0.014
positive regulation of signal transduction GO:0009967 56 0.014
multicellular organismal reproductive process GO:0048609 35 0.014
Worm
chemical homeostasis GO:0048878 49 0.014
innate immune response GO:0045087 13 0.014
regulation of phosphate metabolic process GO:0019220 43 0.014
negative regulation of oocyte development GO:0060283 2 0.014
negative regulation of mesodermal cell fate specification GO:0042662 3 0.014
gland development GO:0048732 143 0.014
Fly
translational initiation GO:0006413 3 0.014
Fly
pancreatic d cell development GO:0003324 1 0.014
muscle organ development GO:0007517 101 0.014
axon guidance GO:0007411 86 0.014
regulation of binding GO:0051098 3 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.013
metal ion transport GO:0030001 58 0.013
regulation of apoptotic process GO:0042981 98 0.013
calcium ion import GO:0070509 4 0.013
male meiosis GO:0007140 2 0.013
positive regulation of cell activation GO:0050867 1 0.013
positive regulation of catabolic process GO:0009896 4 0.013
negative regulation of gastrulation GO:2000542 11 0.013
gtp catabolic process GO:0006184 2 0.013
humoral immune response GO:0006959 5 0.013
methylation GO:0032259 22 0.013
cartilage development GO:0051216 96 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.013
Worm
negative regulation of developmental process GO:0051093 65 0.013
negative regulation of cell fate commitment GO:0010454 13 0.013
regulation of dna replication GO:0006275 3 0.013
peptide transport GO:0015833 1 0.013
cell migration involved in gastrulation GO:0042074 79 0.013
cellular component assembly involved in morphogenesis GO:0010927 107 0.013
regulation of organelle organization GO:0033043 29 0.012
positive regulation of calcium ion dependent exocytosis GO:0045956 1 0.012
lateral line system development GO:0048925 76 0.012
regulation of chromosome segregation GO:0051983 1 0.012
organelle localization GO:0051640 49 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
cytokinesis GO:0000910 3 0.012
positive regulation of muscle tissue development GO:1901863 1 0.012
regulation of neurogenesis GO:0050767 87 0.012
positive regulation of muscle cell differentiation GO:0051149 1 0.012
retina development in camera type eye GO:0060041 146 0.012
positive regulation of rna metabolic process GO:0051254 59 0.012
positive regulation of nucleic acid templated transcription GO:1903508 57 0.012
female sex differentiation GO:0046660 4 0.012
regulation of embryonic development GO:0045995 47 0.011
gene silencing by rna GO:0031047 4 0.011
epiboly GO:0090504 41 0.011
axis specification GO:0009798 43 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
calcium ion dependent exocytosis GO:0017156 1 0.011
negative regulation of metabolic process GO:0009892 86 0.011
endodermal cell fate determination GO:0007493 2 0.011
positive regulation of immune effector process GO:0002699 3 0.011
regulation of inflammatory response GO:0050727 2 0.011
mesodermal cell fate commitment GO:0001710 14 0.011
meiotic nuclear division GO:0007126 4 0.011
Worm Fly
stem cell division GO:0017145 1 0.011
reproductive process GO:0022414 40 0.011
Worm
regulation of nervous system development GO:0051960 90 0.011
cell proliferation GO:0008283 80 0.011
response to growth factor GO:0070848 39 0.011
axon extension GO:0048675 45 0.010
protein polymerization GO:0051258 4 0.010
cellular response to steroid hormone stimulus GO:0071383 31 0.010
positive regulation of secretion by cell GO:1903532 1 0.010
germ cell development GO:0007281 22 0.010
Worm
positive regulation of secretion GO:0051047 1 0.010
striated muscle tissue development GO:0014706 110 0.010
calcium ion transport GO:0006816 18 0.010
developmental process involved in reproduction GO:0003006 27 0.010
Worm
negative regulation of cell cycle process GO:0010948 9 0.010

eif4e1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.022
bone disease DOID:0080001 0 0.011
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011
bone development disease DOID:0080006 0 0.011