Danio rerio

0 known processes

zgc:113019

zgc:113019

zgc:113019 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule metabolic process GO:0044260 391 0.097
modification dependent macromolecule catabolic process GO:0043632 3 0.083
modification dependent protein catabolic process GO:0019941 3 0.075
nitrogen compound metabolic process GO:0006807 319 0.075
ubiquitin dependent protein catabolic process GO:0006511 3 0.070
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.058
cellular protein metabolic process GO:0044267 129 0.051
protein metabolic process GO:0019538 183 0.050
proteasomal protein catabolic process GO:0010498 2 0.049
aging GO:0007568 2 0.046
cellular protein catabolic process GO:0044257 4 0.044
maintenance of location GO:0051235 4 0.043
cellular nitrogen compound metabolic process GO:0034641 290 0.042
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.041
nucleocytoplasmic transport GO:0006913 4 0.041
regulation of cellular amino acid metabolic process GO:0006521 0 0.041
protein polyubiquitination GO:0000209 4 0.040
organic acid metabolic process GO:0006082 31 0.038
oxoacid metabolic process GO:0043436 31 0.038
cellular macromolecule biosynthetic process GO:0034645 224 0.036
amine metabolic process GO:0009308 2 0.035
adult behavior GO:0030534 2 0.035
regulation of cellular ketone metabolic process GO:0010565 7 0.035
positive regulation of transport GO:0051050 2 0.034
rna metabolic process GO:0016070 219 0.034
biosynthetic process GO:0009058 294 0.033
regulation of cellular amine metabolic process GO:0033238 0 0.032
rna polyadenylation GO:0043631 2 0.032
protein localization to nucleus GO:0034504 3 0.032
response to chemical GO:0042221 320 0.031
regionalization GO:0003002 274 0.031
multicellular organism growth GO:0035264 4 0.031
regulation of epithelial cell proliferation GO:0050678 3 0.031
central nervous system development GO:0007417 387 0.030
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.030
protein acetylation GO:0006473 2 0.029
larval development GO:0002164 2 0.029
carboxylic acid metabolic process GO:0019752 22 0.029
phagocytosis GO:0006909 3 0.028
cognition GO:0050890 1 0.028
single organism metabolic process GO:0044710 217 0.028
macromolecule modification GO:0043412 111 0.027
nucleobase containing compound biosynthetic process GO:0034654 205 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.027
regulation of protein ubiquitination GO:0031396 3 0.027
positive regulation of cellular component biogenesis GO:0044089 3 0.027
regulation of cell communication GO:0010646 232 0.027
gene expression GO:0010467 252 0.027
cellular protein modification process GO:0006464 100 0.026
positive regulation of cellular amine metabolic process GO:0033240 0 0.026
developmental growth GO:0048589 166 0.026
organonitrogen compound metabolic process GO:1901564 74 0.026
heterocycle metabolic process GO:0046483 290 0.025
cellular ketone metabolic process GO:0042180 11 0.025
stem cell proliferation GO:0072089 4 0.025
protein import into nucleus GO:0006606 3 0.025
cellular component morphogenesis GO:0032989 336 0.025
peptidyl lysine acetylation GO:0018394 2 0.024
cellular amine metabolic process GO:0044106 2 0.024
regulation of establishment of protein localization GO:0070201 4 0.024
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.023
protein targeting to nucleus GO:0044744 3 0.023
single organism nuclear import GO:1902593 3 0.023
signal transduction GO:0007165 455 0.023
organic cyclic compound metabolic process GO:1901360 301 0.023
regulation of metabolic process GO:0019222 359 0.022
single organism localization GO:1902578 225 0.022
regulation of multicellular organism growth GO:0040014 4 0.022
regulation of dna templated transcription elongation GO:0032784 3 0.022
mrna 3 end processing GO:0031124 2 0.022
cellular aromatic compound metabolic process GO:0006725 295 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.022
anterior posterior pattern specification GO:0009952 152 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
b cell activation GO:0042113 2 0.022
protein import GO:0017038 3 0.021
muscle structure development GO:0061061 196 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
internal protein amino acid acetylation GO:0006475 2 0.021
small molecule metabolic process GO:0044281 77 0.021
dna templated transcription elongation GO:0006354 3 0.021
nuclear import GO:0051170 3 0.021
primary neural tube formation GO:0014020 1 0.021
embryo development ending in birth or egg hatching GO:0009792 271 0.021
regulation of protein transport GO:0051223 3 0.021
organic substance biosynthetic process GO:1901576 289 0.021
cell projection organization GO:0030030 284 0.021
regulation of gene expression GO:0010468 265 0.020
single organism transport GO:0044765 206 0.020
positive regulation of epithelial cell proliferation GO:0050679 1 0.020
regulation of cellular metabolic process GO:0031323 320 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
cell projection morphogenesis GO:0048858 244 0.020
rna localization GO:0006403 4 0.020
positive regulation of muscle organ development GO:0048636 1 0.020
organic cyclic compound biosynthetic process GO:1901362 223 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.020
regulation of primary metabolic process GO:0080090 311 0.020
positive regulation of cellular process GO:0048522 201 0.020
dorsal ventral pattern formation GO:0009953 125 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
positive regulation of cell activation GO:0050867 1 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
cellular biosynthetic process GO:0044249 286 0.019
rna 3 end processing GO:0031123 2 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
peptidyl threonine phosphorylation GO:0018107 1 0.019
sensory organ development GO:0007423 393 0.019
heart development GO:0007507 313 0.019
chemosensory behavior GO:0007635 1 0.019
system process GO:0003008 185 0.019
mitochondrion organization GO:0007005 4 0.019
maternal determination of anterior posterior axis embryo GO:0008358 4 0.019
negative regulation of kinase activity GO:0033673 4 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.019
negative regulation of macromolecule metabolic process GO:0010605 76 0.018
transport GO:0006810 220 0.018
nuclear transport GO:0051169 4 0.018
mononuclear cell proliferation GO:0032943 1 0.018
rna biosynthetic process GO:0032774 181 0.018
response to hexose GO:0009746 3 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
regulation of reproductive process GO:2000241 4 0.018
peptide transport GO:0015833 1 0.018
regulation of protein catabolic process GO:0042176 1 0.018
double strand break repair GO:0006302 3 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
locomotion GO:0040011 313 0.018
cell part morphogenesis GO:0032990 246 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
carboxylic acid catabolic process GO:0046395 3 0.017
response to monosaccharide GO:0034284 3 0.017
internal peptidyl lysine acetylation GO:0018393 2 0.017
regulation of sequestering of calcium ion GO:0051282 4 0.017
regulation of protein targeting GO:1903533 2 0.017
response to carbohydrate GO:0009743 3 0.017
autophagy GO:0006914 4 0.017
golgi vesicle transport GO:0048193 3 0.017
transcription dna templated GO:0006351 181 0.017
response to glucose GO:0009749 3 0.016
negative regulation of map kinase activity GO:0043407 2 0.016
lymphocyte proliferation GO:0046651 1 0.016
regulation of cell activation GO:0050865 1 0.016
protein modification process GO:0036211 100 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
response to corticosteroid GO:0031960 1 0.016
cellular response to organic substance GO:0071310 105 0.016
nucleic acid metabolic process GO:0090304 244 0.016
cell morphogenesis GO:0000902 289 0.016
positive regulation of biological process GO:0048518 253 0.016
regulation of synapse organization GO:0050807 3 0.016
protein homooligomerization GO:0051260 3 0.016
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
forebrain regionalization GO:0021871 4 0.016
lipid storage GO:0019915 1 0.016
negative regulation of protein transport GO:0051224 3 0.016
cell cycle arrest GO:0007050 1 0.016
cellular amide metabolic process GO:0043603 4 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
regulation of endothelial cell proliferation GO:0001936 1 0.015
stem cell maintenance GO:0019827 4 0.015
generation of neurons GO:0048699 385 0.015
small molecule catabolic process GO:0044282 3 0.015
er to golgi vesicle mediated transport GO:0006888 1 0.015
regulation of synapse assembly GO:0051963 3 0.015
regulation of metal ion transport GO:0010959 4 0.015
cell matrix adhesion GO:0007160 4 0.015
establishment of localization GO:0051234 244 0.015
regulation of dna recombination GO:0000018 2 0.015
cellular component disassembly GO:0022411 1 0.015
negative regulation of epithelial cell proliferation GO:0050680 1 0.015
protein dephosphorylation GO:0006470 3 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
tube closure GO:0060606 1 0.015
fertilization GO:0009566 3 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
cellular response to starvation GO:0009267 1 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.015
positive regulation of secretion GO:0051047 1 0.015
calcium ion import GO:0070509 4 0.015
neuron differentiation GO:0030182 353 0.015
regulation of signaling GO:0023051 235 0.015
negative regulation of cellular process GO:0048523 283 0.015
regulation of cytokine production GO:0001817 3 0.014
g2 dna damage checkpoint GO:0031572 3 0.014
response to drug GO:0042493 3 0.014
hormone transport GO:0009914 2 0.014
tube morphogenesis GO:0035239 349 0.014
embryonic limb morphogenesis GO:0030326 2 0.014
leukocyte proliferation GO:0070661 1 0.014
sequestering of calcium ion GO:0051208 3 0.014
response to glucocorticoid GO:0051384 1 0.014
atp catabolic process GO:0006200 4 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
double strand break repair via homologous recombination GO:0000724 1 0.014
regulation of signal transduction GO:0009966 225 0.014
regulation of transcription dna templated GO:0006355 213 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
female gonad development GO:0008585 4 0.014
hormone secretion GO:0046879 2 0.014
female sex differentiation GO:0046660 4 0.014
response to nutrient GO:0007584 3 0.014
neuron projection morphogenesis GO:0048812 161 0.014
cytoplasm organization GO:0007028 4 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
neuroblast proliferation GO:0007405 2 0.013
negative regulation of myeloid cell differentiation GO:0045638 1 0.013
regulation of cell shape GO:0008360 1 0.013
cellular component movement GO:0006928 335 0.013
b cell differentiation GO:0030183 1 0.013
regulation of protein complex assembly GO:0043254 3 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
vasculature development GO:0001944 278 0.013
sequestering of metal ion GO:0051238 3 0.013
protein acylation GO:0043543 3 0.013
regulation of histone methylation GO:0031060 3 0.013
positive regulation of catabolic process GO:0009896 4 0.013
cell surface receptor signaling pathway GO:0007166 325 0.013
regulation of blood pressure GO:0008217 1 0.013
leukocyte homeostasis GO:0001776 2 0.013
brain development GO:0007420 293 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
membrane invagination GO:0010324 1 0.013
dna templated transcription initiation GO:0006352 1 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
cell substrate adhesion GO:0031589 4 0.013
regulation of developmental process GO:0050793 247 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
positive regulation of striated muscle tissue development GO:0045844 1 0.013
single fertilization GO:0007338 3 0.013
protein localization to plasma membrane GO:0072659 1 0.013
sister chromatid cohesion GO:0007062 2 0.013
female meiotic division GO:0007143 2 0.013
digestive system development GO:0055123 289 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
regulation of binding GO:0051098 3 0.013
response to amino acid GO:0043200 2 0.013
organic acid catabolic process GO:0016054 3 0.013
gastrulation GO:0007369 208 0.013
histone h3 k4 methylation GO:0051568 2 0.013
negative regulation of signaling GO:0023057 96 0.013
response to stress GO:0006950 263 0.012
spermatid differentiation GO:0048515 2 0.012
somatic stem cell maintenance GO:0035019 1 0.012
release of sequestered calcium ion into cytosol GO:0051209 3 0.012
peptide metabolic process GO:0006518 1 0.012
cellular response to external stimulus GO:0071496 2 0.012
positive regulation of cytokine production GO:0001819 2 0.012
regulation of receptor activity GO:0010469 2 0.012
positive regulation of muscle tissue development GO:1901863 1 0.012
regulation of response to stimulus GO:0048583 269 0.012
pathway restricted smad protein phosphorylation GO:0060389 1 0.012
regulation of calcium ion transport GO:0051924 2 0.012
meiotic cell cycle process GO:1903046 3 0.012
catecholamine metabolic process GO:0006584 2 0.012
nucleic acid templated transcription GO:0097659 181 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
neurotransmitter transport GO:0006836 2 0.012
cytosolic calcium ion transport GO:0060401 3 0.012
organelle organization GO:0006996 227 0.012
meiotic nuclear division GO:0007126 4 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
regulation of dendrite development GO:0050773 3 0.012
digestive tract development GO:0048565 265 0.012
macromolecular complex disassembly GO:0032984 1 0.012
response to external stimulus GO:0009605 264 0.012
regulation of multicellular organismal process GO:0051239 277 0.012
axis specification GO:0009798 43 0.012
mrna polyadenylation GO:0006378 2 0.012
interspecies interaction between organisms GO:0044419 4 0.012
muscle cell differentiation GO:0042692 139 0.012
eye development GO:0001654 277 0.012
regulation of hormone secretion GO:0046883 2 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
liver development GO:0001889 96 0.011
immune system development GO:0002520 191 0.011
exocytosis GO:0006887 1 0.011
programmed cell death GO:0012501 119 0.011
specification of axis polarity GO:0065001 4 0.011
negative regulation of catabolic process GO:0009895 3 0.011
stem cell division GO:0017145 1 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
localization within membrane GO:0051668 1 0.011
embryonic organ development GO:0048568 381 0.011
secondary metabolic process GO:0019748 3 0.011
negative regulation of gliogenesis GO:0014014 1 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
mesenchyme development GO:0060485 127 0.011
convergent extension GO:0060026 118 0.011
intracellular mrna localization GO:0008298 1 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
single organism organelle organization GO:1902589 199 0.011
positive regulation of histone modification GO:0031058 1 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
striated muscle cell differentiation GO:0051146 129 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
regulation of protein metabolic process GO:0051246 56 0.011
regulation of mesenchymal cell proliferation GO:0010464 1 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
apoptotic process involved in development GO:1902742 2 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
positive regulation of chromatin modification GO:1903310 1 0.011
alpha amino acid metabolic process GO:1901605 3 0.011
protein modification by small protein removal GO:0070646 1 0.011
regulation of inflammatory response GO:0050727 2 0.011
intestinal absorption GO:0050892 2 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
viral process GO:0016032 1 0.011
sleep GO:0030431 1 0.011
positive regulation of multi organism process GO:0043902 3 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.010
neuron neuron synaptic transmission GO:0007270 1 0.010
b cell mediated immunity GO:0019724 3 0.010
signal transduction in absence of ligand GO:0038034 1 0.010
regulation of blood vessel size GO:0050880 2 0.010
carbohydrate homeostasis GO:0033500 1 0.010
spermatid development GO:0007286 2 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
transmembrane transport GO:0055085 120 0.010
regulation of cellular component organization GO:0051128 86 0.010
positive regulation of inflammatory response GO:0050729 1 0.010
macromolecule biosynthetic process GO:0009059 227 0.010
regulation of mitochondrion organization GO:0010821 1 0.010
tyrosine phosphorylation of stat protein GO:0007260 1 0.010
negative regulation of sequestering of calcium ion GO:0051283 4 0.010
muscle organ development GO:0007517 101 0.010
translational initiation GO:0006413 3 0.010
cellular response to endogenous stimulus GO:0071495 68 0.010
response to endogenous stimulus GO:0009719 83 0.010
neuron projection development GO:0031175 180 0.010
phagocytosis engulfment GO:0006911 1 0.010
positive regulation of macromolecule metabolic process GO:0010604 93 0.010
positive regulation of leukocyte mediated immunity GO:0002705 1 0.010
cellular response to nutrient levels GO:0031669 2 0.010
apoptotic process GO:0006915 116 0.010

zgc:113019 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.031
disease of metabolism DOID:0014667 0 0.026
inherited metabolic disorder DOID:655 0 0.026
disease of anatomical entity DOID:7 0 0.023
cancer DOID:162 0 0.018
organ system cancer DOID:0050686 0 0.018
musculoskeletal system disease DOID:17 0 0.016
nervous system disease DOID:863 0 0.014