Danio rerio

0 known processes

eif4a3

eukaryotic translation initiation factor 4A, isoform 3

(Aliases: eIF4A-III,ddx48,MGC56139,zgc:56139)

eif4a3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of mrna processing GO:0050684 3 0.796
Mouse
meiotic nuclear division GO:0007126 4 0.588
Worm
regulation of mrna splicing via spliceosome GO:0048024 3 0.515
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.477
Human Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.450
Human Worm
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.441
cellular macromolecule metabolic process GO:0044260 391 0.411
Human Yeast Mouse Fly
regulation of gene expression GO:0010468 265 0.386
Human Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.373
Mouse
regulation of metabolic process GO:0019222 359 0.360
Human Mouse Fly
alternative mrna splicing via spliceosome GO:0000380 1 0.318
organic cyclic compound biosynthetic process GO:1901362 223 0.296
Mouse
multicellular organismal reproductive process GO:0048609 35 0.275
Worm Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.261
Human Yeast Mouse Fly
locomotion GO:0040011 313 0.244
Worm
nucleobase containing compound biosynthetic process GO:0034654 205 0.240
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.238
Human Yeast Mouse Fly
gene expression GO:0010467 252 0.238
Human Yeast Mouse Fly
nitrogen compound metabolic process GO:0006807 319 0.229
Human Yeast Mouse Fly
aging GO:0007568 2 0.207
rna metabolic process GO:0016070 219 0.202
Human Yeast Mouse Fly
multi organism process GO:0051704 134 0.200
Worm Fly
single organism reproductive process GO:0044702 40 0.185
Worm Fly
rna splicing GO:0008380 16 0.161
Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.161
Human Mouse
negative regulation of cellular process GO:0048523 283 0.157
Human
transcription dna templated GO:0006351 181 0.153
Mouse
mrna splicing via spliceosome GO:0000398 10 0.153
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.151
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.145
Human Yeast Mouse Fly
heterocycle metabolic process GO:0046483 290 0.143
Human Yeast Mouse Fly
heterocycle biosynthetic process GO:0018130 215 0.136
Mouse
organelle organization GO:0006996 227 0.134
Worm
larval development GO:0002164 2 0.127
Worm
regulation of rna metabolic process GO:0051252 224 0.127
Mouse
negative regulation of gene expression GO:0010629 65 0.119
Human
single organism organelle organization GO:1902589 199 0.117
regulation of nitrogen compound metabolic process GO:0051171 251 0.117
Mouse
macromolecule biosynthetic process GO:0009059 227 0.115
Human Mouse
nucleic acid metabolic process GO:0090304 244 0.111
Human Yeast Mouse Fly
cellular aromatic compound metabolic process GO:0006725 295 0.109
Human Yeast Mouse Fly
aromatic compound biosynthetic process GO:0019438 217 0.104
Mouse
negative regulation of biological process GO:0048519 304 0.103
Human
regulation of cell cycle process GO:0010564 20 0.097
Worm
rna localization GO:0006403 4 0.093
Fly
meiotic cell cycle process GO:1903046 3 0.088
modification dependent macromolecule catabolic process GO:0043632 3 0.086
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.081
Human
microtubule based process GO:0007017 60 0.080
cellular biosynthetic process GO:0044249 286 0.079
Human Mouse
organelle fission GO:0048285 23 0.078
Worm
signal transduction GO:0007165 455 0.073
Fly
rna biosynthetic process GO:0032774 181 0.072
Mouse
regulation of meiotic cell cycle GO:0051445 1 0.070
Worm
cellular macromolecule biosynthetic process GO:0034645 224 0.069
Human Mouse
regulation of cellular metabolic process GO:0031323 320 0.067
Human Mouse Fly
generation of neurons GO:0048699 385 0.067
regulation of macromolecule biosynthetic process GO:0010556 225 0.066
Human Mouse
lipid storage GO:0019915 1 0.065
regulation of synapse organization GO:0050807 3 0.065
protein complex disassembly GO:0043241 1 0.065
multicellular organism growth GO:0035264 4 0.064
regulation of transcription dna templated GO:0006355 213 0.063
Mouse
germ cell development GO:0007281 22 0.061
Worm Fly
response to stress GO:0006950 263 0.060
Fly
gamete generation GO:0007276 33 0.060
Worm Fly
immune system development GO:0002520 191 0.058
macromolecular complex subunit organization GO:0043933 74 0.058
Fly
establishment of localization GO:0051234 244 0.057
multicellular organism reproduction GO:0032504 35 0.054
Worm Fly
cell cycle process GO:0022402 53 0.054
Worm
cellular component assembly GO:0022607 170 0.054
Fly
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.053
Worm Fly
cell division GO:0051301 20 0.053
Worm
cell cycle GO:0007049 93 0.053
Worm
cellular component disassembly GO:0022411 1 0.052
regulation of rna biosynthetic process GO:2001141 213 0.050
Mouse
modification dependent protein catabolic process GO:0019941 3 0.050
nucleocytoplasmic transport GO:0006913 4 0.049
neuromuscular synaptic transmission GO:0007274 2 0.049
regulation of cell communication GO:0010646 232 0.048
Fly
regulation of erk1 and erk2 cascade GO:0070372 4 0.048
Fly
response to external stimulus GO:0009605 264 0.046
rna splicing via transesterification reactions GO:0000375 10 0.045
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.045
Human Mouse
regulation of signal transduction GO:0009966 225 0.045
Fly
positive regulation of biological process GO:0048518 253 0.045
Human Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.042
Mouse
phosphate containing compound metabolic process GO:0006796 108 0.042
Human Fly
mitotic cell cycle GO:0000278 64 0.041
biosynthetic process GO:0009058 294 0.040
Human Mouse
mrna processing GO:0006397 14 0.039
Mouse
protein metabolic process GO:0019538 183 0.039
Human
regulation of cellular component organization GO:0051128 86 0.039
Worm
meiotic chromosome segregation GO:0045132 3 0.039
single fertilization GO:0007338 3 0.038
regulation of multicellular organism growth GO:0040014 4 0.038
protein complex assembly GO:0006461 30 0.038
Fly
apoptotic process GO:0006915 116 0.037
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.037
Human Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.037
Human Mouse
nuclear division GO:0000280 23 0.037
Worm
regulation of multicellular organismal development GO:2000026 223 0.036
ubiquitin dependent protein catabolic process GO:0006511 3 0.035
translational initiation GO:0006413 3 0.035
programmed cell death GO:0012501 119 0.035
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.035
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.034
single organism metabolic process GO:0044710 217 0.034
Human Fly
regulation of cell differentiation GO:0045595 142 0.034
multi organism reproductive process GO:0044703 36 0.034
Worm Fly
intracellular mrna localization GO:0008298 1 0.033
Fly
regulation of primary metabolic process GO:0080090 311 0.032
Human Mouse
cell surface receptor signaling pathway GO:0007166 325 0.032
sexual reproduction GO:0019953 36 0.032
Worm Fly
proteasomal protein catabolic process GO:0010498 2 0.032
positive regulation of cellular process GO:0048522 201 0.031
Human Mouse Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.031
Human Mouse
neuron projection morphogenesis GO:0048812 161 0.031
positive regulation of rna biosynthetic process GO:1902680 57 0.031
Mouse
macromolecular complex disassembly GO:0032984 1 0.031
negative regulation of developmental process GO:0051093 65 0.031
regulation of cell cycle GO:0051726 52 0.030
Worm
phagocytosis GO:0006909 3 0.030
regulation of developmental process GO:0050793 247 0.030
nuclear export GO:0051168 1 0.030
regulation of protein catabolic process GO:0042176 1 0.030
negative regulation of metabolic process GO:0009892 86 0.029
Human
cellular protein catabolic process GO:0044257 4 0.029
neuron differentiation GO:0030182 353 0.029
catabolic process GO:0009056 32 0.029
Human
negative regulation of cellular metabolic process GO:0031324 77 0.029
Human
mrna metabolic process GO:0016071 20 0.029
Human Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.029
Human
negative regulation of protein phosphorylation GO:0001933 4 0.028
cell projection morphogenesis GO:0048858 244 0.028
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.028
negative regulation of rna splicing GO:0033119 1 0.027
hematopoietic or lymphoid organ development GO:0048534 191 0.027
cellular component biogenesis GO:0044085 178 0.027
Yeast Fly
spliceosomal snrnp assembly GO:0000387 2 0.027
response to chemical GO:0042221 320 0.027
positive regulation of ras protein signal transduction GO:0046579 1 0.026
Fly
regulation of synapse assembly GO:0051963 3 0.026
reproductive process GO:0022414 40 0.026
Worm Fly
negative regulation of cell cycle GO:0045786 14 0.025
immune system process GO:0002376 241 0.025
oocyte anterior posterior axis specification GO:0007314 4 0.025
Fly
organic substance catabolic process GO:1901575 28 0.025
Human
cell death GO:0008219 121 0.025
death GO:0016265 121 0.025
microtubule cytoskeleton organization GO:0000226 33 0.025
regulation of gene expression epigenetic GO:0040029 11 0.024
regulation of mrna metabolic process GO:1903311 6 0.024
Mouse
lateral inhibition GO:0046331 1 0.024
negative regulation of multicellular organismal process GO:0051241 69 0.024
cellular component morphogenesis GO:0032989 336 0.024
positive regulation of catabolic process GO:0009896 4 0.024
regulation of nucleic acid templated transcription GO:1903506 213 0.023
Mouse
cell motility GO:0048870 244 0.023
stem cell proliferation GO:0072089 4 0.023
regulation of biosynthetic process GO:0009889 250 0.023
Human Mouse
cell morphogenesis GO:0000902 289 0.023
developmental growth GO:0048589 166 0.023
negative regulation of synapse assembly GO:0051964 2 0.023
regulation of cell proliferation GO:0042127 37 0.023
Worm
cellular protein metabolic process GO:0044267 129 0.023
Human
regulation of multicellular organismal process GO:0051239 277 0.023
macromolecule catabolic process GO:0009057 15 0.022
Human
hemopoiesis GO:0030097 183 0.022
nucleic acid templated transcription GO:0097659 181 0.022
Mouse
cell proliferation GO:0008283 80 0.022
Worm
cytoskeleton organization GO:0007010 96 0.022
meiotic spindle organization GO:0000212 1 0.021
oxoacid metabolic process GO:0043436 31 0.021
regulation of signaling GO:0023051 235 0.021
Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.021
Mouse
cell cell signaling GO:0007267 52 0.021
positive regulation of cellular component biogenesis GO:0044089 3 0.021
rna processing GO:0006396 25 0.021
Yeast Mouse Fly
regulation of biological quality GO:0065008 263 0.021
maintenance of location GO:0051235 4 0.020
transcription from rna polymerase iii promoter GO:0006383 1 0.020
positive regulation of metabolic process GO:0009893 108 0.020
Human Mouse Fly
regulation of stem cell proliferation GO:0072091 2 0.020
protein polymerization GO:0051258 4 0.020
regulation of protein complex assembly GO:0043254 3 0.020
anterior posterior pattern specification GO:0009952 152 0.020
Fly
protein complex subunit organization GO:0071822 46 0.019
Fly
pole plasm assembly GO:0007315 4 0.019
Fly
dorsal ventral pattern formation GO:0009953 125 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.019
protein complex biogenesis GO:0070271 30 0.019
Fly
fertilization GO:0009566 3 0.019
anterior posterior axis specification GO:0009948 20 0.019
Fly
eye development GO:0001654 277 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.018
positive regulation of protein complex assembly GO:0031334 2 0.018
cell migration GO:0016477 237 0.018
regulation of reproductive process GO:2000241 4 0.018
posttranscriptional gene silencing by rna GO:0035194 3 0.018
regulation of rna splicing GO:0043484 8 0.017
Mouse
embryonic organ morphogenesis GO:0048562 274 0.017
Human
cellular component movement GO:0006928 335 0.017
regulation of response to stimulus GO:0048583 269 0.017
Fly
spindle assembly involved in mitosis GO:0090307 1 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
transport GO:0006810 220 0.017
zymogen activation GO:0031638 3 0.017
centrosome organization GO:0051297 1 0.017
vasculature development GO:0001944 278 0.016
nuclear transport GO:0051169 4 0.016
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.016
cell part morphogenesis GO:0032990 246 0.016
amine metabolic process GO:0009308 2 0.016
positive regulation of gene expression GO:0010628 71 0.016
Human Mouse
regulation of cell shape GO:0008360 1 0.015
gene silencing GO:0016458 4 0.015
single organism transport GO:0044765 206 0.015
organelle assembly GO:0070925 110 0.015
regulation of molecular function GO:0065009 70 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
chromosome organization GO:0051276 31 0.014
proteolysis GO:0006508 38 0.014
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.014
regulation of cell development GO:0060284 100 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
central nervous system development GO:0007417 387 0.014
cellular macromolecular complex assembly GO:0034622 24 0.014
cellular response to external stimulus GO:0071496 2 0.014
regionalization GO:0003002 274 0.014
Fly
regulation of nuclear division GO:0051783 9 0.014
Worm
blood vessel morphogenesis GO:0048514 216 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
response to external biotic stimulus GO:0043207 97 0.014
meiosis i GO:0007127 1 0.013
response to abiotic stimulus GO:0009628 122 0.013
growth GO:0040007 174 0.013
organic acid metabolic process GO:0006082 31 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
regulation of organelle organization GO:0033043 29 0.013
Worm
regulation of apoptotic process GO:0042981 98 0.013
muscle structure development GO:0061061 196 0.013
muscle organ development GO:0007517 101 0.013
neuron development GO:0048666 262 0.012
compound eye development GO:0048749 2 0.012
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.012
Fly
cellular response to extracellular stimulus GO:0031668 2 0.012
vesicle mediated transport GO:0016192 22 0.012
regulation of cell death GO:0010941 103 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
Mouse
meiotic cell cycle GO:0051321 5 0.012
Worm
protein polyubiquitination GO:0000209 4 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
sensory organ development GO:0007423 393 0.012
reproductive structure development GO:0048608 5 0.012
Worm
negative regulation of rna metabolic process GO:0051253 48 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
negative regulation of cell differentiation GO:0045596 46 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
regulation of phosphorus metabolic process GO:0051174 43 0.011
Fly
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
cellular response to nutrient levels GO:0031669 2 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
endocytosis GO:0006897 16 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
cellular protein modification process GO:0006464 100 0.011
small molecule metabolic process GO:0044281 77 0.011
Human
spindle assembly GO:0051225 2 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.011
Mouse
developmental process involved in reproduction GO:0003006 27 0.011
Worm Fly
mitotic cell cycle process GO:1903047 48 0.011
positive regulation of transcription dna templated GO:0045893 57 0.011
Mouse
cellular response to chemical stimulus GO:0070887 157 0.011
spermatid development GO:0007286 2 0.011
microtubule polymerization GO:0046785 2 0.011
regulation of inflammatory response GO:0050727 2 0.011
rna catabolic process GO:0006401 7 0.010
Human
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
heterocycle catabolic process GO:0046700 15 0.010
Human
adult behavior GO:0030534 2 0.010
protein acylation GO:0043543 3 0.010
response to organic substance GO:0010033 153 0.010
cellular response to starvation GO:0009267 1 0.010
negative regulation of defense response GO:0031348 2 0.010
positive regulation of biosynthetic process GO:0009891 68 0.010
Human Mouse
negative regulation of mrna processing GO:0050686 1 0.010
ras protein signal transduction GO:0007265 7 0.010
Fly
protein import into nucleus GO:0006606 3 0.010
posttranscriptional regulation of gene expression GO:0010608 14 0.010
Human

eif4a3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012