Danio rerio

74 known processes

tyms

thymidylate synthase

(Aliases: zgc:77659,zgc:56465)

tyms biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
alpha amino acid metabolic process GO:1901605 3 0.340
transport GO:0006810 220 0.295
cellular biosynthetic process GO:0044249 286 0.290
camera type eye development GO:0043010 222 0.225
sensory organ development GO:0007423 393 0.213
aging GO:0007568 2 0.171
dna catabolic process GO:0006308 1 0.168
sister chromatid cohesion GO:0007062 2 0.166
double strand break repair via homologous recombination GO:0000724 1 0.162
recombinational repair GO:0000725 1 0.159
organic cyclic compound metabolic process GO:1901360 301 0.147
regulation of multicellular organism growth GO:0040014 4 0.142
cellular nitrogen compound metabolic process GO:0034641 290 0.139
peptidyl serine phosphorylation GO:0018105 1 0.128
cellular modified amino acid metabolic process GO:0006575 3 0.127
retina development in camera type eye GO:0060041 146 0.126
establishment of localization GO:0051234 244 0.125
locomotion GO:0040011 313 0.124
meiosis i GO:0007127 1 0.124
chromosome segregation GO:0007059 12 0.113
eye development GO:0001654 277 0.113
single organism metabolic process GO:0044710 217 0.099
single organism localization GO:1902578 225 0.098
pyrimidine containing compound metabolic process GO:0072527 3 0.093
cellular aromatic compound metabolic process GO:0006725 295 0.091
peptidyl serine modification GO:0018209 2 0.091
hematopoietic or lymphoid organ development GO:0048534 191 0.085
ion transport GO:0006811 114 0.085
negative regulation of chromosome organization GO:2001251 1 0.081
cellular response to reactive oxygen species GO:0034614 2 0.078
regulation of establishment of protein localization GO:0070201 4 0.076
larval development GO:0002164 2 0.076
protein targeting to nucleus GO:0044744 3 0.075
chromosome organization involved in meiosis GO:0070192 1 0.074
modification dependent protein catabolic process GO:0019941 3 0.074
carboxylic acid metabolic process GO:0019752 22 0.071
organic acid metabolic process GO:0006082 31 0.071
maintenance of location GO:0051235 4 0.069
cellular amino acid biosynthetic process GO:0008652 2 0.069
multicellular organism growth GO:0035264 4 0.069
meiotic nuclear division GO:0007126 4 0.067
double strand break repair GO:0006302 3 0.064
heterocycle metabolic process GO:0046483 290 0.064
cellular macromolecule biosynthetic process GO:0034645 224 0.063
histone phosphorylation GO:0016572 2 0.063
intra s dna damage checkpoint GO:0031573 1 0.062
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.062
nitrogen compound metabolic process GO:0006807 319 0.061
protein import into nucleus GO:0006606 3 0.061
nucleoside monophosphate catabolic process GO:0009125 4 0.057
organic substance biosynthetic process GO:1901576 289 0.056
dicarboxylic acid metabolic process GO:0043648 1 0.055
amine metabolic process GO:0009308 2 0.055
response to organic substance GO:0010033 153 0.054
Human
specification of symmetry GO:0009799 204 0.053
response to stress GO:0006950 263 0.052
embryo development ending in birth or egg hatching GO:0009792 271 0.052
Worm
single organism reproductive process GO:0044702 40 0.052
maintenance of dna repeat elements GO:0043570 2 0.051
biosynthetic process GO:0009058 294 0.050
cellular response to stress GO:0033554 62 0.050
pteridine containing compound metabolic process GO:0042558 3 0.050
phosphorylation GO:0016310 69 0.049
macromolecule localization GO:0033036 54 0.049
modification dependent macromolecule catabolic process GO:0043632 3 0.049
response to inorganic substance GO:0010035 38 0.048
regulation of cellular amino acid metabolic process GO:0006521 0 0.048
single organism transport GO:0044765 206 0.048
cellular localization GO:0051641 97 0.048
oocyte maturation GO:0001556 4 0.047
mitotic dna integrity checkpoint GO:0044774 4 0.047
cellular response to chemical stimulus GO:0070887 157 0.046
phosphorus metabolic process GO:0006793 109 0.046
regulation of protein catabolic process GO:0042176 1 0.045
response to oxygen containing compound GO:1901700 55 0.045
single organism organelle organization GO:1902589 199 0.045
cellular response to organic substance GO:0071310 105 0.043
regulation of biological quality GO:0065008 263 0.040
regulation of primary metabolic process GO:0080090 311 0.040
positive regulation of nuclease activity GO:0032075 1 0.040
digestive tract development GO:0048565 265 0.039
multi organism process GO:0051704 134 0.038
oxoacid metabolic process GO:0043436 31 0.038
regulation of protein ubiquitination GO:0031396 3 0.038
positive regulation of catabolic process GO:0009896 4 0.038
negative regulation of apoptotic process GO:0043066 55 0.036
nuclear transport GO:0051169 4 0.036
determination of left right symmetry GO:0007368 179 0.035
reproductive process GO:0022414 40 0.034
positive regulation of lipid catabolic process GO:0050996 1 0.034
cellular amino acid metabolic process GO:0006520 7 0.034
death GO:0016265 121 0.033
cellular amine metabolic process GO:0044106 2 0.033
cleavage furrow formation GO:0036089 2 0.032
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.032
regulation of response to stimulus GO:0048583 269 0.032
growth GO:0040007 174 0.032
cellular ketone metabolic process GO:0042180 11 0.031
regulation of protein import into nucleus GO:0042306 2 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
immunoglobulin mediated immune response GO:0016064 3 0.030
cofactor metabolic process GO:0051186 15 0.030
regulation of protein transport GO:0051223 3 0.029
single organism nuclear import GO:1902593 3 0.029
peptidyl threonine phosphorylation GO:0018107 1 0.029
cellular component disassembly GO:0022411 1 0.029
response to metal ion GO:0010038 34 0.029
rna localization GO:0006403 4 0.029
proteasomal protein catabolic process GO:0010498 2 0.028
nucleic acid metabolic process GO:0090304 244 0.028
organonitrogen compound metabolic process GO:1901564 74 0.028
positive regulation of cellular catabolic process GO:0031331 3 0.028
chromosome organization GO:0051276 31 0.027
extrinsic apoptotic signaling pathway GO:0097191 3 0.026
heterocycle biosynthetic process GO:0018130 215 0.026
response to chemical GO:0042221 320 0.026
Human
nucleocytoplasmic transport GO:0006913 4 0.025
heart development GO:0007507 313 0.025
protein import GO:0017038 3 0.025
aromatic compound biosynthetic process GO:0019438 217 0.025
regulation of dna replication GO:0006275 3 0.025
nucleobase containing small molecule metabolic process GO:0055086 32 0.025
protein acetylation GO:0006473 2 0.025
regulation of cell death GO:0010941 103 0.025
cardiac muscle cell differentiation GO:0055007 30 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
programmed cell death GO:0012501 119 0.024
cellular protein catabolic process GO:0044257 4 0.024
regulation of meiotic cell cycle GO:0051445 1 0.024
regulation of catalytic activity GO:0050790 55 0.023
protein heterooligomerization GO:0051291 1 0.023
deoxyribonucleotide biosynthetic process GO:0009263 1 0.023
gland development GO:0048732 143 0.023
intracellular steroid hormone receptor signaling pathway GO:0030518 5 0.023
single organism biosynthetic process GO:0044711 71 0.022
regulation of protein targeting GO:1903533 2 0.022
negative regulation of catabolic process GO:0009895 3 0.022
intracellular signal transduction GO:0035556 85 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
regulation of binding GO:0051098 3 0.021
organelle organization GO:0006996 227 0.021
phosphate containing compound metabolic process GO:0006796 108 0.021
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.021
response to drug GO:0042493 3 0.021
cell migration GO:0016477 237 0.021
regulation of intracellular protein transport GO:0033157 3 0.020
microtubule based process GO:0007017 60 0.020
zymogen activation GO:0031638 3 0.020
developmental growth GO:0048589 166 0.020
protein phosphorylation GO:0006468 47 0.020
regulation of protein localization to nucleus GO:1900180 2 0.019
adult behavior GO:0030534 2 0.019
nuclear import GO:0051170 3 0.019
protein localization to nucleus GO:0034504 3 0.019
negative regulation of kinase activity GO:0033673 4 0.019
protein complex biogenesis GO:0070271 30 0.019
response to lipid GO:0033993 60 0.019
negative regulation of biological process GO:0048519 304 0.019
negative regulation of meiotic cell cycle GO:0051447 1 0.019
monovalent inorganic cation transport GO:0015672 42 0.019
cell surface receptor signaling pathway GO:0007166 325 0.018
peptidyl threonine modification GO:0018210 1 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
response to hydrogen peroxide GO:0042542 3 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
cell death GO:0008219 121 0.018
response to wounding GO:0009611 116 0.018
cellular component movement GO:0006928 335 0.018
regulation of embryonic development GO:0045995 47 0.018
ubiquitin dependent protein catabolic process GO:0006511 3 0.018
cellular protein modification process GO:0006464 100 0.017
neural retina development GO:0003407 49 0.017
small gtpase mediated signal transduction GO:0007264 8 0.017
protein metabolic process GO:0019538 183 0.017
retina morphogenesis in camera type eye GO:0060042 79 0.017
negative regulation of cell death GO:0060548 60 0.017
rna metabolic process GO:0016070 219 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.017
response to organic cyclic compound GO:0014070 51 0.016
rna transport GO:0050658 2 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
regulation of deoxyribonuclease activity GO:0032070 1 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
macromolecule modification GO:0043412 111 0.016
microtubule polymerization GO:0046785 2 0.016
organ regeneration GO:0031100 1 0.015
positive regulation of chromatin modification GO:1903310 1 0.015
microtubule depolymerization GO:0007019 1 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
mrna metabolic process GO:0016071 20 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
cell proliferation GO:0008283 80 0.015
water soluble vitamin metabolic process GO:0006767 1 0.015
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
nucleobase containing compound transport GO:0015931 2 0.015
negative regulation of macromolecule metabolic process GO:0010605 76 0.015
protein polymerization GO:0051258 4 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
organic substance transport GO:0071702 58 0.014
regeneration GO:0031099 91 0.014
transcription dna templated GO:0006351 181 0.014
cellular catabolic process GO:0044248 27 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
negative regulation of chromatin modification GO:1903309 1 0.014
negative regulation of gene expression GO:0010629 65 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
regulation of phosphate metabolic process GO:0019220 43 0.013
regulation of proteolysis GO:0030162 24 0.013
mitotic cell cycle process GO:1903047 48 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.013
purine ribonucleotide metabolic process GO:0009150 27 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
catabolic process GO:0009056 32 0.013
apoptotic process GO:0006915 116 0.013
regulation of neuron apoptotic process GO:0043523 17 0.013
cellular component biogenesis GO:0044085 178 0.012
cell aging GO:0007569 2 0.012
regulation of programmed cell death GO:0043067 101 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
erythrocyte homeostasis GO:0034101 55 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
cellular lipid catabolic process GO:0044242 3 0.012
regulation of phosphorylation GO:0042325 26 0.012
macromolecule catabolic process GO:0009057 15 0.012
negative regulation of histone methylation GO:0031061 1 0.011
negative regulation of protein transport GO:0051224 3 0.011
cartilage development GO:0051216 96 0.011
protein localization GO:0008104 40 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.011
cell cycle arrest GO:0007050 1 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
cell type specific apoptotic process GO:0097285 22 0.011
urogenital system development GO:0001655 97 0.011
positive regulation of biological process GO:0048518 253 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
negative regulation of secretion GO:0051048 2 0.011
response to biotic stimulus GO:0009607 97 0.011
wound healing GO:0042060 90 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
signal transduction GO:0007165 455 0.010
ribonucleoside biosynthetic process GO:0042455 2 0.010
protein complex disassembly GO:0043241 1 0.010
establishment of localization in cell GO:0051649 77 0.010
digestive system development GO:0055123 289 0.010
negative regulation of response to dna damage stimulus GO:2001021 3 0.010
regulation of protein depolymerization GO:1901879 1 0.010
camera type eye morphogenesis GO:0048593 108 0.010
protein homooligomerization GO:0051260 3 0.010
nucleic acid phosphodiester bond hydrolysis GO:0090305 6 0.010
positive regulation of cellular process GO:0048522 201 0.010
atp catabolic process GO:0006200 4 0.010

tyms disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.014