Danio rerio

0 known processes

uba3

ubiquitin-like modifier activating enzyme 3

(Aliases: wu:fb75e04,zgc:55528,ube1c,wu:fc37b11)

uba3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.519
Worm
cellular macromolecule metabolic process GO:0044260 391 0.277
Worm
locomotion GO:0040011 313 0.257
Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.255
Worm
biosynthetic process GO:0009058 294 0.227
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.204
regulation of gene expression GO:0010468 265 0.183
regulation of metabolic process GO:0019222 359 0.179
regulation of nitrogen compound metabolic process GO:0051171 251 0.176
cellular nitrogen compound metabolic process GO:0034641 290 0.167
regulation of cellular biosynthetic process GO:0031326 245 0.166
heterocycle metabolic process GO:0046483 290 0.160
regulation of cellular metabolic process GO:0031323 320 0.140
cellular aromatic compound metabolic process GO:0006725 295 0.122
lateral inhibition GO:0046331 1 0.109
regulation of macromolecule biosynthetic process GO:0010556 225 0.109
protein acetylation GO:0006473 2 0.107
organic cyclic compound metabolic process GO:1901360 301 0.106
nucleic acid metabolic process GO:0090304 244 0.102
regulation of rna metabolic process GO:0051252 224 0.093
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.088
gene expression GO:0010467 252 0.085
cellular nitrogen compound biosynthetic process GO:0044271 218 0.083
transcription dna templated GO:0006351 181 0.080
regulation of macromolecule metabolic process GO:0060255 317 0.078
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.077
nucleobase containing compound metabolic process GO:0006139 274 0.076
negative regulation of biological process GO:0048519 304 0.074
regulation of transcription dna templated GO:0006355 213 0.071
aromatic compound biosynthetic process GO:0019438 217 0.070
protein localization to plasma membrane GO:0072659 1 0.069
transcription from rna polymerase ii promoter GO:0006366 80 0.069
nitrogen compound metabolic process GO:0006807 319 0.067
cellular component movement GO:0006928 335 0.067
regulation of nucleic acid templated transcription GO:1903506 213 0.066
heterocycle biosynthetic process GO:0018130 215 0.066
single fertilization GO:0007338 3 0.065
response to external stimulus GO:0009605 264 0.064
nucleic acid templated transcription GO:0097659 181 0.063
macromolecule biosynthetic process GO:0009059 227 0.062
multi organism process GO:0051704 134 0.061
Worm
cellular macromolecule biosynthetic process GO:0034645 224 0.061
nucleobase containing compound biosynthetic process GO:0034654 205 0.059
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.058
protein dephosphorylation GO:0006470 3 0.058
multicellular organism reproduction GO:0032504 35 0.057
Worm
cellular carbohydrate metabolic process GO:0044262 4 0.056
rna biosynthetic process GO:0032774 181 0.056
hatching GO:0035188 4 0.055
regulation of primary metabolic process GO:0080090 311 0.053
regulation of rna biosynthetic process GO:2001141 213 0.051
response to stress GO:0006950 263 0.051
response to chemical GO:0042221 320 0.051
cellular response to external stimulus GO:0071496 2 0.050
fertilization GO:0009566 3 0.050
aging GO:0007568 2 0.049
cellular biosynthetic process GO:0044249 286 0.046
regionalization GO:0003002 274 0.045
viral process GO:0016032 1 0.045
organic substance biosynthetic process GO:1901576 289 0.043
cell morphogenesis involved in differentiation GO:0000904 195 0.043
ubiquitin dependent protein catabolic process GO:0006511 3 0.043
modification dependent protein catabolic process GO:0019941 3 0.043
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.042
cytokinesis GO:0000910 3 0.042
reproduction GO:0000003 40 0.041
Worm
regulation of biological quality GO:0065008 263 0.041
multi organism cellular process GO:0044764 2 0.040
dorsal ventral pattern formation GO:0009953 125 0.040
regulation of biosynthetic process GO:0009889 250 0.040
double strand break repair GO:0006302 3 0.038
membrane fusion GO:0061025 2 0.037
positive regulation of biological process GO:0048518 253 0.037
organic cyclic compound biosynthetic process GO:1901362 223 0.036
cell death GO:0008219 121 0.036
Worm
cellular response to nutrient levels GO:0031669 2 0.036
positive regulation of rna biosynthetic process GO:1902680 57 0.035
ribonucleoside monophosphate catabolic process GO:0009158 4 0.035
single organism metabolic process GO:0044710 217 0.035
ncrna metabolic process GO:0034660 12 0.033
positive regulation of cellular metabolic process GO:0031325 94 0.033
cellular response to extracellular stimulus GO:0031668 2 0.033
modification dependent macromolecule catabolic process GO:0043632 3 0.032
rna metabolic process GO:0016070 219 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.032
response to nutrient GO:0007584 3 0.032
interspecies interaction between organisms GO:0044419 4 0.032
regulation of protein ubiquitination GO:0031396 3 0.031
protein acylation GO:0043543 3 0.031
macromolecule modification GO:0043412 111 0.031
Worm
protein metabolic process GO:0019538 183 0.031
Worm
cell migration GO:0016477 237 0.030
neuron development GO:0048666 262 0.030
generation of neurons GO:0048699 385 0.029
regulation of protein complex assembly GO:0043254 3 0.029
cellular component morphogenesis GO:0032989 336 0.029
neuron differentiation GO:0030182 353 0.028
negative regulation of metabolic process GO:0009892 86 0.028
axonogenesis GO:0007409 152 0.028
signal transduction GO:0007165 455 0.028
regulation of meiotic cell cycle GO:0051445 1 0.028
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.027
protein polymerization GO:0051258 4 0.027
regulation of dna templated transcription elongation GO:0032784 3 0.027
cell part morphogenesis GO:0032990 246 0.027
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.026
negative regulation of cellular process GO:0048523 283 0.026
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.026
maintenance of location GO:0051235 4 0.026
multicellular organism growth GO:0035264 4 0.026
stem cell division GO:0017145 1 0.025
negative regulation of synapse assembly GO:0051964 2 0.025
single organism organelle organization GO:1902589 199 0.025
death GO:0016265 121 0.025
Worm
autophagy GO:0006914 4 0.025
cell motility GO:0048870 244 0.025
positive regulation of cellular process GO:0048522 201 0.025
establishment of synaptic vesicle localization GO:0097480 1 0.025
establishment of localization GO:0051234 244 0.024
chemotaxis GO:0006935 104 0.024
phagocytosis GO:0006909 3 0.024
positive regulation of transport GO:0051050 2 0.023
purine nucleoside monophosphate catabolic process GO:0009128 4 0.023
regulation of signal transduction GO:0009966 225 0.023
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.023
sensory organ development GO:0007423 393 0.023
positive regulation of cellular catabolic process GO:0031331 3 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.023
mitotic g2 m transition checkpoint GO:0044818 3 0.023
cellular protein catabolic process GO:0044257 4 0.022
protein complex disassembly GO:0043241 1 0.022
mitotic dna damage checkpoint GO:0044773 4 0.022
cell surface receptor signaling pathway GO:0007166 325 0.022
neuron projection guidance GO:0097485 86 0.022
regulation of molecular function GO:0065009 70 0.022
locomotor rhythm GO:0045475 3 0.021
nuclear migration GO:0007097 3 0.021
organism emergence from protective structure GO:0071684 4 0.021
taxis GO:0042330 109 0.021
localization of cell GO:0051674 244 0.021
regulation of signaling GO:0023051 235 0.021
neuron neuron synaptic transmission GO:0007270 1 0.021
peptidyl lysine acetylation GO:0018394 2 0.021
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.021
meiotic nuclear division GO:0007126 4 0.020
g2 dna damage checkpoint GO:0031572 3 0.020
positive regulation of nucleoside metabolic process GO:0045979 1 0.020
recombinational repair GO:0000725 1 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
protein stabilization GO:0050821 2 0.020
kidney development GO:0001822 92 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.020
positive regulation of catabolic process GO:0009896 4 0.020
positive regulation of cell cycle GO:0045787 3 0.020
protein modification process GO:0036211 100 0.020
Worm
response to drug GO:0042493 3 0.020
cellular component disassembly GO:0022411 1 0.019
regulation of response to stimulus GO:0048583 269 0.019
nucleoside monophosphate catabolic process GO:0009125 4 0.019
dendrite guidance GO:0070983 0 0.019
multicellular organismal reproductive process GO:0048609 35 0.019
Worm
cellular protein modification process GO:0006464 100 0.019
Worm
regulation of epithelial cell proliferation GO:0050678 3 0.019
cell cycle g1 s phase transition GO:0044843 1 0.019
leukocyte proliferation GO:0070661 1 0.019
atp catabolic process GO:0006200 4 0.018
apoptotic process GO:0006915 116 0.018
Worm
microtubule organizing center organization GO:0031023 1 0.018
cell projection morphogenesis GO:0048858 244 0.018
cell projection organization GO:0030030 284 0.018
organic acid metabolic process GO:0006082 31 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
carbohydrate homeostasis GO:0033500 1 0.018
negative regulation of cell cycle process GO:0010948 9 0.018
single organism localization GO:1902578 225 0.018
regulation of cell communication GO:0010646 232 0.018
mitotic g2 dna damage checkpoint GO:0007095 3 0.017
positive regulation of rna metabolic process GO:0051254 59 0.017
lipid storage GO:0019915 1 0.017
double strand break repair via homologous recombination GO:0000724 1 0.017
positive regulation of nucleotide catabolic process GO:0030813 1 0.017
positive regulation of multi organism process GO:0043902 3 0.017
gtp metabolic process GO:0046039 4 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
cytoskeleton dependent cytokinesis GO:0061640 3 0.017
cell morphogenesis GO:0000902 289 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
response to abiotic stimulus GO:0009628 122 0.016
programmed cell death GO:0012501 119 0.016
Worm
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
nuclear import GO:0051170 3 0.016
response to carbohydrate GO:0009743 3 0.016
macromolecular complex disassembly GO:0032984 1 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
cellular response to dna damage stimulus GO:0006974 24 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
axis specification GO:0009798 43 0.016
amine metabolic process GO:0009308 2 0.016
regulation of binding GO:0051098 3 0.016
centrosome cycle GO:0007098 1 0.016
positive regulation of secretion GO:0051047 1 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
dna metabolic process GO:0006259 27 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
nuclear transport GO:0051169 4 0.015
immune system process GO:0002376 241 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
positive regulation of protein complex assembly GO:0031334 2 0.015
ncrna catabolic process GO:0034661 1 0.015
regulation of synapse organization GO:0050807 3 0.015
neuroblast proliferation GO:0007405 2 0.015
single organism nuclear import GO:1902593 3 0.015
mitotic dna integrity checkpoint GO:0044774 4 0.015
meiotic cell cycle process GO:1903046 3 0.015
system process GO:0003008 185 0.015
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
rna localization GO:0006403 4 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
transcription from rna polymerase iii promoter GO:0006383 1 0.015
negative regulation of nuclear division GO:0051784 3 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
rna processing GO:0006396 25 0.015
cellular amine metabolic process GO:0044106 2 0.015
positive regulation of nucleic acid templated transcription GO:1903508 57 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.015
regulation of protein transport GO:0051223 3 0.014
gamete generation GO:0007276 33 0.014
positive regulation of cellular biosynthetic process GO:0031328 68 0.014
germ cell development GO:0007281 22 0.014
regulation of neural precursor cell proliferation GO:2000177 3 0.014
organic substance catabolic process GO:1901575 28 0.014
stem cell proliferation GO:0072089 4 0.014
stem cell maintenance GO:0019827 4 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
positive regulation of biosynthetic process GO:0009891 68 0.014
organelle organization GO:0006996 227 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.014
adult behavior GO:0030534 2 0.014
oxoacid metabolic process GO:0043436 31 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
regulation of mitochondrion organization GO:0010821 1 0.014
centrosome organization GO:0051297 1 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
cellular response to starvation GO:0009267 1 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.013
renal system development GO:0072001 94 0.013
regulation of synapse assembly GO:0051963 3 0.013
protein import into nucleus GO:0006606 3 0.013
negative regulation of cell death GO:0060548 60 0.013
regulation of developmental process GO:0050793 247 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
glucose homeostasis GO:0042593 1 0.013
meiosis i GO:0007127 1 0.013
negative regulation of mapk cascade GO:0043409 4 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
protein import GO:0017038 3 0.013
muscle structure development GO:0061061 196 0.013
hormone transport GO:0009914 2 0.013
modification of morphology or physiology of other organism GO:0035821 4 0.013
female sex differentiation GO:0046660 4 0.013
regulation of hormone secretion GO:0046883 2 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
compound eye development GO:0048749 2 0.013
protein localization to nucleus GO:0034504 3 0.013
post golgi vesicle mediated transport GO:0006892 1 0.013
blood vessel development GO:0001568 246 0.013
cell cell signaling GO:0007267 52 0.013
hepaticobiliary system development GO:0061008 98 0.013
regulation of cell projection assembly GO:0060491 4 0.013
muscle organ development GO:0007517 101 0.013
organelle assembly GO:0070925 110 0.013
negative regulation of signaling GO:0023057 96 0.012
single organism reproductive process GO:0044702 40 0.012
cellular protein metabolic process GO:0044267 129 0.012
Worm
negative regulation of signal transduction GO:0009968 94 0.012
cellular response to stress GO:0033554 62 0.012
homeostatic process GO:0042592 142 0.012
regulation of chromosome segregation GO:0051983 1 0.012
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.012
lymphocyte proliferation GO:0046651 1 0.012
b cell activation GO:0042113 2 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
regulation of cell activation GO:0050865 1 0.012
regulation of cell death GO:0010941 103 0.012
mitochondrion organization GO:0007005 4 0.012
carbohydrate metabolic process GO:0005975 12 0.012
ncrna processing GO:0034470 8 0.012
membrane lipid biosynthetic process GO:0046467 2 0.012
skin development GO:0043588 54 0.012
mononuclear cell proliferation GO:0032943 1 0.012
cellular ketone metabolic process GO:0042180 11 0.012
cell cycle g2 m phase transition GO:0044839 4 0.012
actin filament polymerization GO:0030041 2 0.012
regulation of organ growth GO:0046620 3 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
protein secretion GO:0009306 1 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
liver development GO:0001889 96 0.011
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.011
tube morphogenesis GO:0035239 349 0.011
gtp catabolic process GO:0006184 2 0.011
protein polyubiquitination GO:0000209 4 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
synaptic vesicle transport GO:0048489 1 0.011
peptide transport GO:0015833 1 0.011
reproductive process GO:0022414 40 0.011
Worm
response to antibiotic GO:0046677 1 0.011
cognition GO:0050890 1 0.011
sex determination GO:0007530 1 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
cell division GO:0051301 20 0.011
chemosensory behavior GO:0007635 1 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
behavior GO:0007610 74 0.011
Worm
synaptic vesicle localization GO:0097479 1 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
regulation of protein polymerization GO:0032271 2 0.011
cell proliferation GO:0008283 80 0.011
brain development GO:0007420 293 0.011
response to monosaccharide GO:0034284 3 0.011
phosphorus metabolic process GO:0006793 109 0.011
cellular component biogenesis GO:0044085 178 0.011
eye development GO:0001654 277 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
regulation of mrna processing GO:0050684 3 0.011
positive regulation of metabolic process GO:0009893 108 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
negative regulation of programmed cell death GO:0043069 58 0.010
neuron projection morphogenesis GO:0048812 161 0.010
neuromuscular synaptic transmission GO:0007274 2 0.010
ribosomal small subunit biogenesis GO:0042274 2 0.010
negative regulation of kinase activity GO:0033673 4 0.010
positive regulation of dna templated transcription elongation GO:0032786 1 0.010
cellular component assembly GO:0022607 170 0.010
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.010
mitochondrial transport GO:0006839 2 0.010
organonitrogen compound metabolic process GO:1901564 74 0.010
regulation of inflammatory response GO:0050727 2 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
ovulation cycle GO:0042698 2 0.010
protein targeting to nucleus GO:0044744 3 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.010
i kappab kinase nf kappab signaling GO:0007249 4 0.010
urogenital system development GO:0001655 97 0.010
regulation of cytokine production GO:0001817 3 0.010
regulation of protein localization to plasma membrane GO:1903076 1 0.010
peptidyl tyrosine dephosphorylation GO:0035335 1 0.010
response to hexose GO:0009746 3 0.010
dna templated transcription initiation GO:0006352 1 0.010
axon guidance GO:0007411 86 0.010

uba3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.021
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
cancer DOID:162 0 0.016