Danio rerio

0 known processes

sigmar1

sigma non-opioid intracellular receptor 1

(Aliases: MGC56378,oprs1,zgc:56378)

sigmar1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.137
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.070
sensory organ development GO:0007423 393 0.065
positive regulation of transport GO:0051050 2 0.062
aging GO:0007568 2 0.061
morphogenesis of an epithelium GO:0002009 333 0.055
tube morphogenesis GO:0035239 349 0.054
cellular protein catabolic process GO:0044257 4 0.053
regulation of gtp catabolic process GO:0033124 2 0.052
negative regulation of biological process GO:0048519 304 0.048
organonitrogen compound metabolic process GO:1901564 74 0.045
guanosine containing compound catabolic process GO:1901069 2 0.045
embryo development ending in birth or egg hatching GO:0009792 271 0.044
single organism localization GO:1902578 225 0.043
regulation of cytokine production GO:0001817 3 0.041
transport GO:0006810 220 0.041
nucleocytoplasmic transport GO:0006913 4 0.041
embryonic organ development GO:0048568 381 0.038
establishment of localization GO:0051234 244 0.038
negative regulation of catabolic process GO:0009895 3 0.038
regulation of multicellular organismal process GO:0051239 277 0.038
establishment of protein localization to organelle GO:0072594 4 0.037
regulation of nucleotide catabolic process GO:0030811 2 0.037
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.036
multicellular organism growth GO:0035264 4 0.035
regulation of cell communication GO:0010646 232 0.035
ubiquitin dependent protein catabolic process GO:0006511 3 0.035
response to external stimulus GO:0009605 264 0.035
organic substance transport GO:0071702 58 0.034
regulation of autophagy GO:0010506 3 0.034
immune system process GO:0002376 241 0.033
growth GO:0040007 174 0.031
gtp metabolic process GO:0046039 4 0.031
regulation of establishment of protein localization GO:0070201 4 0.031
negative regulation of cellular process GO:0048523 283 0.031
proteasomal protein catabolic process GO:0010498 2 0.031
nuclear transport GO:0051169 4 0.030
regulation of nucleocytoplasmic transport GO:0046822 2 0.030
tube closure GO:0060606 1 0.029
guanosine containing compound metabolic process GO:1901068 4 0.029
specification of symmetry GO:0009799 204 0.029
single organism nuclear import GO:1902593 3 0.029
protein import GO:0017038 3 0.028
single organism transport GO:0044765 206 0.027
negative regulation of cellular catabolic process GO:0031330 3 0.027
gtp catabolic process GO:0006184 2 0.026
phagocytosis GO:0006909 3 0.026
regulation of metabolic process GO:0019222 359 0.026
cellular component morphogenesis GO:0032989 336 0.026
embryonic organ morphogenesis GO:0048562 274 0.026
cellular amine metabolic process GO:0044106 2 0.025
modification dependent macromolecule catabolic process GO:0043632 3 0.025
amine metabolic process GO:0009308 2 0.024
nuclear import GO:0051170 3 0.024
protein targeting to nucleus GO:0044744 3 0.024
autophagy GO:0006914 4 0.024
signal transduction GO:0007165 455 0.024
protein import into nucleus GO:0006606 3 0.023
cellular response to extracellular stimulus GO:0031668 2 0.023
camera type eye development GO:0043010 222 0.022
organelle fusion GO:0048284 3 0.022
regulation of protein targeting GO:1903533 2 0.022
regulation of biological quality GO:0065008 263 0.021
organic acid metabolic process GO:0006082 31 0.021
cellular nitrogen compound metabolic process GO:0034641 290 0.021
determination of heart left right asymmetry GO:0061371 117 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
intracellular signal transduction GO:0035556 85 0.021
hormone secretion GO:0046879 2 0.021
cellular response to external stimulus GO:0071496 2 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
oxoacid metabolic process GO:0043436 31 0.020
peptidyl serine phosphorylation GO:0018105 1 0.020
cell death GO:0008219 121 0.020
Human
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
determination of left right symmetry GO:0007368 179 0.020
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.020
eye development GO:0001654 277 0.020
modification dependent protein catabolic process GO:0019941 3 0.020
cellular response to nutrient levels GO:0031669 2 0.019
regulation of gene expression GO:0010468 265 0.019
hormone transport GO:0009914 2 0.019
small molecule metabolic process GO:0044281 77 0.019
epithelial tube morphogenesis GO:0060562 148 0.019
chordate embryonic development GO:0043009 271 0.019
cellular nitrogen compound biosynthetic process GO:0044271 218 0.019
regulation of gtpase activity GO:0043087 2 0.019
gene expression GO:0010467 252 0.019
regulation of primary metabolic process GO:0080090 311 0.019
primary neural tube formation GO:0014020 1 0.018
regulation of hormone secretion GO:0046883 2 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
negative regulation of multicellular organismal process GO:0051241 69 0.018
cellular biosynthetic process GO:0044249 286 0.018
protein localization to nucleus GO:0034504 3 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
rna export from nucleus GO:0006405 1 0.018
digestive system development GO:0055123 289 0.018
nitrogen compound metabolic process GO:0006807 319 0.018
death GO:0016265 121 0.017
Human
mitochondrion organization GO:0007005 4 0.017
stem cell proliferation GO:0072089 4 0.017
regulation of cell activation GO:0050865 1 0.017
regulation of signal transduction GO:0009966 225 0.017
heart development GO:0007507 313 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.017
liver development GO:0001889 96 0.017
hepaticobiliary system development GO:0061008 98 0.017
programmed cell death GO:0012501 119 0.017
Human
organic cyclic compound metabolic process GO:1901360 301 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
regulation of multicellular organism growth GO:0040014 4 0.017
regulation of developmental process GO:0050793 247 0.017
biosynthetic process GO:0009058 294 0.016
regulation of signaling GO:0023051 235 0.016
maintenance of location GO:0051235 4 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
brain development GO:0007420 293 0.016
neurotransmitter transport GO:0006836 2 0.016
regulation of response to stimulus GO:0048583 269 0.016
regulation of protein catabolic process GO:0042176 1 0.016
cellular response to starvation GO:0009267 1 0.015
response to monosaccharide GO:0034284 3 0.015
golgi vesicle transport GO:0048193 3 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
cell morphogenesis GO:0000902 289 0.015
regulation of cell death GO:0010941 103 0.015
Human
membrane fusion GO:0061025 2 0.015
cellular localization GO:0051641 97 0.015
positive regulation of cell adhesion GO:0045785 1 0.015
single organism membrane fusion GO:0044801 2 0.015
generation of neurons GO:0048699 385 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.014
apoptotic process GO:0006915 116 0.014
Human
positive regulation of secretion by cell GO:1903532 1 0.014
positive regulation of biological process GO:0048518 253 0.014
positive regulation of catabolic process GO:0009896 4 0.014
adult behavior GO:0030534 2 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
hemopoiesis GO:0030097 183 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
regulation of protein complex assembly GO:0043254 3 0.014
regulation of reproductive process GO:2000241 4 0.013
catabolic process GO:0009056 32 0.013
peptide transport GO:0015833 1 0.013
establishment of localization in cell GO:0051649 77 0.013
response to chemical GO:0042221 320 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
gastrulation GO:0007369 208 0.013
positive regulation of secretion GO:0051047 1 0.013
response to corticosteroid GO:0031960 1 0.013
intracellular transport GO:0046907 32 0.013
regulation of binding GO:0051098 3 0.013
cellular ketone metabolic process GO:0042180 11 0.013
rna biosynthetic process GO:0032774 181 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
heterocycle metabolic process GO:0046483 290 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
macromolecule localization GO:0033036 54 0.013
regulation of apoptotic process GO:0042981 98 0.013
Human
positive regulation of cell cycle GO:0045787 3 0.013
negative regulation of signaling GO:0023057 96 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
calcium mediated signaling GO:0019722 2 0.012
female sex differentiation GO:0046660 4 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
immune system development GO:0002520 191 0.012
response to hydrogen peroxide GO:0042542 3 0.012
regulation of localization GO:0032879 104 0.012
regulation of lipid transport GO:0032368 4 0.012
protein localization to plasma membrane GO:0072659 1 0.012
regulation of molecular function GO:0065009 70 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
response to organic substance GO:0010033 153 0.012
regulation of catalytic activity GO:0050790 55 0.012
heart looping GO:0001947 94 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
response to stress GO:0006950 263 0.012
regulation of protein transport GO:0051223 3 0.012
macromolecule modification GO:0043412 111 0.012
negative regulation of cytokine production GO:0001818 1 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.011
response to nutrient GO:0007584 3 0.011
protein n linked glycosylation GO:0006487 1 0.011
homeostatic process GO:0042592 142 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
negative regulation of translation GO:0017148 1 0.011
somite development GO:0061053 96 0.011
circulatory system process GO:0003013 87 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
chemical homeostasis GO:0048878 49 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
negative regulation of protein complex assembly GO:0031333 1 0.011
nucleobase containing compound metabolic process GO:0006139 274 0.011
compound eye development GO:0048749 2 0.011
gastrulation with mouth forming second GO:0001702 44 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
cellular aromatic compound metabolic process GO:0006725 295 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
neurotransmitter secretion GO:0007269 2 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
response to lipid GO:0033993 60 0.011
cellular component movement GO:0006928 335 0.011
negative regulation of nuclear division GO:0051784 3 0.011
nuclear export GO:0051168 1 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
response to drug GO:0042493 3 0.011
regulation of peptidase activity GO:0052547 23 0.011
meiotic cell cycle process GO:1903046 3 0.011
cellular catabolic process GO:0044248 27 0.011
metal ion homeostasis GO:0055065 26 0.011
protein secretion GO:0009306 1 0.011
cell projection morphogenesis GO:0048858 244 0.011
carbohydrate homeostasis GO:0033500 1 0.011
neuron differentiation GO:0030182 353 0.011
female gonad development GO:0008585 4 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
regulation of organelle assembly GO:1902115 4 0.010
gland development GO:0048732 143 0.010
regulation of multicellular organismal development GO:2000026 223 0.010
nucleic acid transport GO:0050657 2 0.010
neuron development GO:0048666 262 0.010
positive regulation of cytokine production GO:0001819 2 0.010
viral process GO:0016032 1 0.010

sigmar1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.035
disease of anatomical entity DOID:7 0 0.023
Human
nervous system disease DOID:863 0 0.023
Human
inherited metabolic disorder DOID:655 0 0.011