Danio rerio

0 known processes

ell2

elongation factor, RNA polymerase II, 2

(Aliases: wu:fb78f03,sb:cb244,im:3814960,fb78f03,cb244)

ell2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular nitrogen compound metabolic process GO:0034641 290 0.116
Human Fly
heterocycle metabolic process GO:0046483 290 0.097
Human Fly
modification dependent protein catabolic process GO:0019941 3 0.093
aromatic compound biosynthetic process GO:0019438 217 0.091
Human Fly
meiotic nuclear division GO:0007126 4 0.087
cellular macromolecule metabolic process GO:0044260 391 0.084
Human Fly
maintenance of location GO:0051235 4 0.082
regulation of cellular biosynthetic process GO:0031326 245 0.081
Fly
larval development GO:0002164 2 0.074
regulation of synapse assembly GO:0051963 3 0.071
lipid storage GO:0019915 1 0.066
positive regulation of cellular process GO:0048522 201 0.064
Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.064
Human Fly
regulation of biological quality GO:0065008 263 0.060
positive regulation of cellular component biogenesis GO:0044089 3 0.060
regulation of nitrogen compound metabolic process GO:0051171 251 0.059
Fly
regulation of developmental process GO:0050793 247 0.057
aging GO:0007568 2 0.057
phagocytosis GO:0006909 3 0.053
regulation of macromolecule biosynthetic process GO:0010556 225 0.050
Fly
positive regulation of transport GO:0051050 2 0.049
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.049
regulation of cellular metabolic process GO:0031323 320 0.047
Fly
single organism metabolic process GO:0044710 217 0.047
nucleobase containing compound metabolic process GO:0006139 274 0.047
Human Fly
transport GO:0006810 220 0.047
nucleobase containing compound biosynthetic process GO:0034654 205 0.046
Human Fly
synaptic growth at neuromuscular junction GO:0051124 2 0.045
regulation of multicellular organismal process GO:0051239 277 0.044
regulation of primary metabolic process GO:0080090 311 0.043
Fly
cellular amine metabolic process GO:0044106 2 0.043
meiotic cell cycle process GO:1903046 3 0.042
regulation of synapse organization GO:0050807 3 0.041
regulation of macromolecule metabolic process GO:0060255 317 0.039
Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.039
Human Fly
nitrogen compound metabolic process GO:0006807 319 0.039
Human Fly
biosynthetic process GO:0009058 294 0.038
Human Fly
regulation of protein complex assembly GO:0043254 3 0.037
regulation of rna metabolic process GO:0051252 224 0.037
Fly
rna biosynthetic process GO:0032774 181 0.037
Human Fly
cellular biosynthetic process GO:0044249 286 0.036
Human Fly
protein metabolic process GO:0019538 183 0.036
regulation of cell shape GO:0008360 1 0.035
response to stress GO:0006950 263 0.035
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.035
Human Fly
signal transduction GO:0007165 455 0.035
heterocycle biosynthetic process GO:0018130 215 0.035
Human Fly
chemosensory behavior GO:0007635 1 0.034
transcription dna templated GO:0006351 181 0.034
Human Fly
female gonad development GO:0008585 4 0.034
cellular macromolecule biosynthetic process GO:0034645 224 0.033
Human Fly
blood vessel morphogenesis GO:0048514 216 0.033
positive regulation of catabolic process GO:0009896 4 0.032
rna metabolic process GO:0016070 219 0.031
Human Fly
regulation of skeletal muscle fiber development GO:0048742 2 0.031
regulation of nucleic acid templated transcription GO:1903506 213 0.031
Fly
gene expression GO:0010467 252 0.031
Human Fly
cellular response to radiation GO:0071478 4 0.030
organic cyclic compound metabolic process GO:1901360 301 0.030
Human Fly
eye development GO:0001654 277 0.030
positive regulation of macromolecule metabolic process GO:0010604 93 0.030
Fly
embryonic organ development GO:0048568 381 0.029
cellular amino acid metabolic process GO:0006520 7 0.029
positive regulation of cellular catabolic process GO:0031331 3 0.029
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.029
Fly
chromosome organization involved in meiosis GO:0070192 1 0.029
cellular protein metabolic process GO:0044267 129 0.029
circulatory system process GO:0003013 87 0.029
positive regulation of protein complex assembly GO:0031334 2 0.028
sensory organ development GO:0007423 393 0.028
ubiquitin dependent protein catabolic process GO:0006511 3 0.028
amine metabolic process GO:0009308 2 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.028
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.028
regulation of cell communication GO:0010646 232 0.028
multicellular organism growth GO:0035264 4 0.028
cellular protein catabolic process GO:0044257 4 0.027
actin polymerization or depolymerization GO:0008154 2 0.027
proteasomal protein catabolic process GO:0010498 2 0.026
nucleic acid metabolic process GO:0090304 244 0.026
Human Fly
negative regulation of protein kinase activity GO:0006469 4 0.026
regulation of protein polymerization GO:0032271 2 0.026
protein modification process GO:0036211 100 0.026
regulation of metal ion transport GO:0010959 4 0.026
negative regulation of protein phosphorylation GO:0001933 4 0.026
positive regulation of biological process GO:0048518 253 0.026
Fly
cell substrate adhesion GO:0031589 4 0.026
cytokinesis GO:0000910 3 0.026
positive regulation of muscle cell differentiation GO:0051149 1 0.025
death GO:0016265 121 0.025
establishment of protein localization to organelle GO:0072594 4 0.025
organelle organization GO:0006996 227 0.025
modification dependent macromolecule catabolic process GO:0043632 3 0.025
system process GO:0003008 185 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
positive regulation of cellular metabolic process GO:0031325 94 0.024
Fly
cellular modified amino acid metabolic process GO:0006575 3 0.024
response to chemical GO:0042221 320 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
regulation of blood vessel size GO:0050880 2 0.023
phagocytosis engulfment GO:0006911 1 0.023
single organism organelle organization GO:1902589 199 0.023
positive regulation of translation GO:0045727 1 0.023
regulation of signal transduction GO:0009966 225 0.023
cellular component morphogenesis GO:0032989 336 0.022
organic substance biosynthetic process GO:1901576 289 0.022
Human Fly
primary neural tube formation GO:0014020 1 0.022
locomotor rhythm GO:0045475 3 0.022
negative regulation of biological process GO:0048519 304 0.022
regulation of biosynthetic process GO:0009889 250 0.022
Fly
tissue remodeling GO:0048771 4 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
positive regulation of rna metabolic process GO:0051254 59 0.022
Fly
cellular component biogenesis GO:0044085 178 0.021
macromolecule biosynthetic process GO:0009059 227 0.021
Human Fly
organic acid metabolic process GO:0006082 31 0.021
regulation of transcription dna templated GO:0006355 213 0.021
Fly
development of primary female sexual characteristics GO:0046545 4 0.021
regulation of multicellular organism growth GO:0040014 4 0.021
positive regulation of cytoskeleton organization GO:0051495 3 0.021
single organism localization GO:1902578 225 0.021
response to abiotic stimulus GO:0009628 122 0.021
regulation of intracellular ph GO:0051453 1 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
lamellipodium assembly GO:0030032 1 0.021
heart contraction GO:0060047 71 0.021
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.021
cell substrate junction assembly GO:0007044 2 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.020
Fly
homeostatic process GO:0042592 142 0.020
cognition GO:0050890 1 0.020
cellular protein modification process GO:0006464 100 0.020
negative regulation of synapse assembly GO:0051964 2 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.020
Fly
negative regulation of cellular catabolic process GO:0031330 3 0.020
regulation of nucleotide catabolic process GO:0030811 2 0.020
negative regulation of signal transduction GO:0009968 94 0.020
regulation of metabolic process GO:0019222 359 0.020
Fly
oxoacid metabolic process GO:0043436 31 0.019
gtp metabolic process GO:0046039 4 0.019
negative regulation of kinase activity GO:0033673 4 0.019
single organism nuclear import GO:1902593 3 0.019
blood circulation GO:0008015 87 0.019
vasculature development GO:0001944 278 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
generation of neurons GO:0048699 385 0.019
regulation of signaling GO:0023051 235 0.019
striated muscle cell differentiation GO:0051146 129 0.019
positive regulation of protein polymerization GO:0032273 2 0.019
oocyte maturation GO:0001556 4 0.018
positive regulation of cell cycle GO:0045787 3 0.018
gtp catabolic process GO:0006184 2 0.018
positive regulation of biosynthetic process GO:0009891 68 0.018
Fly
rna localization GO:0006403 4 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.018
rna transport GO:0050658 2 0.018
spermatid development GO:0007286 2 0.018
protein import GO:0017038 3 0.018
cell death GO:0008219 121 0.018
cellular response to starvation GO:0009267 1 0.018
heart process GO:0003015 71 0.017
regulation of skeletal muscle tissue development GO:0048641 4 0.017
membrane invagination GO:0010324 1 0.017
cellular ketone metabolic process GO:0042180 11 0.017
nuclear import GO:0051170 3 0.017
protein polymerization GO:0051258 4 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.017
Fly
stem cell maintenance GO:0019827 4 0.017
brain development GO:0007420 293 0.017
cell matrix adhesion GO:0007160 4 0.017
epithelial cell morphogenesis GO:0003382 2 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
p38mapk cascade GO:0038066 1 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
Fly
protein localization to plasma membrane GO:0072659 1 0.016
positive regulation of cellular biosynthetic process GO:0031328 68 0.016
Fly
programmed cell death GO:0012501 119 0.016
adherens junction organization GO:0034332 4 0.016
female meiotic division GO:0007143 2 0.016
specification of symmetry GO:0009799 204 0.016
regulation of cell matrix adhesion GO:0001952 1 0.016
response to organic substance GO:0010033 153 0.016
positive regulation of epithelial cell migration GO:0010634 2 0.016
regulation of blood circulation GO:1903522 32 0.016
regulation of epithelial cell proliferation GO:0050678 3 0.016
positive regulation of metabolic process GO:0009893 108 0.016
Fly
morphogenesis of an epithelium GO:0002009 333 0.016
carbohydrate derivative metabolic process GO:1901135 61 0.016
regulation of filopodium assembly GO:0051489 2 0.016
cell surface receptor signaling pathway GO:0007166 325 0.016
small molecule metabolic process GO:0044281 77 0.016
lamellipodium organization GO:0097581 1 0.016
female sex differentiation GO:0046660 4 0.016
cellular sodium ion homeostasis GO:0006883 1 0.016
angiogenesis GO:0001525 158 0.016
cellular response to growth factor stimulus GO:0071363 39 0.015
organonitrogen compound biosynthetic process GO:1901566 47 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
muscle cell differentiation GO:0042692 139 0.015
central nervous system development GO:0007417 387 0.015
ion transmembrane transport GO:0034220 91 0.015
regulation of biomineral tissue development GO:0070167 2 0.015
lymphocyte proliferation GO:0046651 1 0.015
response to glucocorticoid GO:0051384 1 0.015
protein import into nucleus GO:0006606 3 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
transition metal ion transport GO:0000041 6 0.015
muscle structure development GO:0061061 196 0.015
myotube differentiation GO:0014902 45 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
tube closure GO:0060606 1 0.015
immune system process GO:0002376 241 0.015
actin filament polymerization GO:0030041 2 0.015
medulla oblongata development GO:0021550 4 0.015
long chain fatty acid metabolic process GO:0001676 1 0.015
regulation of anatomical structure morphogenesis GO:0022603 130 0.015
nuclear transport GO:0051169 4 0.014
regulation of systemic arterial blood pressure GO:0003073 1 0.014
hormone secretion GO:0046879 2 0.014
directional locomotion GO:0033058 1 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
regulation of protein transport GO:0051223 3 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
connective tissue development GO:0061448 99 0.014
regulation of sodium ion transport GO:0002028 2 0.014
purine ribonucleotide biosynthetic process GO:0009152 20 0.014
establishment of rna localization GO:0051236 3 0.014
regulation of cell death GO:0010941 103 0.014
autophagy GO:0006914 4 0.014
viral process GO:0016032 1 0.014
regulation of protein catabolic process GO:0042176 1 0.014
positive regulation of map kinase activity GO:0043406 3 0.014
regulation of response to stimulus GO:0048583 269 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
positive regulation of jun kinase activity GO:0043507 2 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
negative regulation of catabolic process GO:0009895 3 0.014
regulation of chromosome segregation GO:0051983 1 0.014
chromatin organization GO:0006325 22 0.014
cellular component assembly GO:0022607 170 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
cell migration GO:0016477 237 0.013
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.013
alpha amino acid metabolic process GO:1901605 3 0.013
blood vessel development GO:0001568 246 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
cellular response to stress GO:0033554 62 0.013
Fly
endosomal transport GO:0016197 2 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.013
establishment of localization GO:0051234 244 0.013
regulation of establishment of protein localization GO:0070201 4 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
cellular transition metal ion homeostasis GO:0046916 3 0.013
epithelial cell differentiation GO:0030855 116 0.013
regulation of jun kinase activity GO:0043506 3 0.013
energy reserve metabolic process GO:0006112 2 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
muscle organ development GO:0007517 101 0.013
sensory perception of chemical stimulus GO:0007606 3 0.013
negative regulation of stem cell differentiation GO:2000737 2 0.013
response to transition metal nanoparticle GO:1990267 28 0.013
regulation of cell projection assembly GO:0060491 4 0.013
regulation of glucose transport GO:0010827 1 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
cellular response to nutrient levels GO:0031669 2 0.013
regulation of binding GO:0051098 3 0.013
protein heterooligomerization GO:0051291 1 0.013
macromolecule modification GO:0043412 111 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
positive regulation of secretion GO:0051047 1 0.012
peptide metabolic process GO:0006518 1 0.012
entrainment of circadian clock GO:0009649 2 0.012
cell morphogenesis GO:0000902 289 0.012
spermatid differentiation GO:0048515 2 0.012
regulation of myotube differentiation GO:0010830 2 0.012
protein targeting to nucleus GO:0044744 3 0.012
branching morphogenesis of a nerve GO:0048755 4 0.012
positive regulation of rna biosynthetic process GO:1902680 57 0.012
Fly
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
golgi vesicle transport GO:0048193 3 0.012
regulation of response to extracellular stimulus GO:0032104 1 0.012
circadian sleep wake cycle process GO:0022410 2 0.012
head development GO:0060322 303 0.012
establishment of epithelial cell polarity GO:0090162 2 0.012
regulation of glucose import GO:0046324 1 0.012
negative regulation of map kinase activity GO:0043407 2 0.012
negative chemotaxis GO:0050919 1 0.012
stem cell fate commitment GO:0048865 1 0.012
response to monosaccharide GO:0034284 3 0.012
regulation of dendrite development GO:0050773 3 0.012
mitochondrial transport GO:0006839 2 0.012
outflow tract morphogenesis GO:0003151 1 0.012
purine nucleotide biosynthetic process GO:0006164 20 0.012
regulation of gtpase activity GO:0043087 2 0.012
protein localization to nucleus GO:0034504 3 0.012
negative regulation of cell communication GO:0010648 96 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
Human Fly
extracellular matrix assembly GO:0085029 1 0.012
striated muscle cell development GO:0055002 108 0.012
neurotransmitter secretion GO:0007269 2 0.012
dna templated transcription elongation GO:0006354 3 0.012
Fly
cell aging GO:0007569 2 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
transmembrane transport GO:0055085 120 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
Fly
protein targeting to membrane GO:0006612 1 0.011
meiotic chromosome segregation GO:0045132 3 0.011
intracellular signal transduction GO:0035556 85 0.011
response to corticosteroid GO:0031960 1 0.011
regulation of ph GO:0006885 3 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
muscle cell development GO:0055001 115 0.011
regulation of cellular ph GO:0030641 1 0.011
protein acylation GO:0043543 3 0.011
translational initiation GO:0006413 3 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
cation transport GO:0006812 81 0.011
protein acetylation GO:0006473 2 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
regulation of dna replication GO:0006275 3 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
positive regulation of camp biosynthetic process GO:0030819 2 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
calcium mediated signaling GO:0019722 2 0.011
response to hexose GO:0009746 3 0.011
mononuclear cell proliferation GO:0032943 1 0.011
regulation of nervous system development GO:0051960 90 0.011
regulation of locomotion GO:0040012 55 0.011
positive regulation of carbohydrate metabolic process GO:0045913 1 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
er nucleus signaling pathway GO:0006984 2 0.011
regulation of blood pressure GO:0008217 1 0.011
skeletal muscle organ development GO:0060538 78 0.011
purine containing compound biosynthetic process GO:0072522 20 0.011
cell junction maintenance GO:0034331 2 0.011
protein secretion GO:0009306 1 0.011
circadian sleep wake cycle GO:0042745 2 0.011
neuroblast differentiation GO:0014016 1 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
response to amino acid GO:0043200 2 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
myotube cell development GO:0014904 35 0.011
coenzyme biosynthetic process GO:0009108 2 0.011
regulation of system process GO:0044057 40 0.010
protein complex disassembly GO:0043241 1 0.010
regulation of p38mapk cascade GO:1900744 1 0.010
regulation of gene expression GO:0010468 265 0.010
Fly
lateral inhibition GO:0046331 1 0.010
regulation of ion transmembrane transporter activity GO:0032412 2 0.010
regulation of cell activation GO:0050865 1 0.010
positive regulation of gtp catabolic process GO:0033126 1 0.010
cellular response to oxygen levels GO:0071453 1 0.010
response to hydrogen peroxide GO:0042542 3 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
compound eye development GO:0048749 2 0.010
adherens junction assembly GO:0034333 1 0.010
mesenchyme development GO:0060485 127 0.010
synaptic target recognition GO:0008039 1 0.010
apoptotic process GO:0006915 116 0.010
response to topologically incorrect protein GO:0035966 2 0.010
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.010
mitochondrion organization GO:0007005 4 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
cellular response to chemical stimulus GO:0070887 157 0.010
regulation of reproductive process GO:2000241 4 0.010
peptidyl serine modification GO:0018209 2 0.010
regulation of endothelial cell differentiation GO:0045601 3 0.010
negative regulation of muscle cell differentiation GO:0051148 1 0.010

ell2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
musculoskeletal system disease DOID:17 0 0.012
organ system cancer DOID:0050686 0 0.011
myopathy DOID:423 0 0.010
muscular disease DOID:0080000 0 0.010
muscle tissue disease DOID:66 0 0.010