Danio rerio

0 known processes

upf3b

UPF3 regulator of nonsense transcripts homolog B (yeast)

(Aliases: zgc:174674,MGC174674,zgc:66390,MGC66390)

upf3b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.305
Worm
cellular biosynthetic process GO:0044249 286 0.085
negative regulation of cellular process GO:0048523 283 0.077
positive regulation of transport GO:0051050 2 0.071
cellular macromolecule biosynthetic process GO:0034645 224 0.067
locomotion GO:0040011 313 0.062
regulation of macromolecule biosynthetic process GO:0010556 225 0.058
fertilization GO:0009566 3 0.055
cellular aromatic compound metabolic process GO:0006725 295 0.054
Worm
lipid storage GO:0019915 1 0.054
cellular nitrogen compound metabolic process GO:0034641 290 0.052
Worm
regulation of cellular amino acid metabolic process GO:0006521 0 0.051
larval development GO:0002164 2 0.051
aging GO:0007568 2 0.048
chordate embryonic development GO:0043009 271 0.047
negative regulation of protein phosphorylation GO:0001933 4 0.044
nucleic acid templated transcription GO:0097659 181 0.044
single fertilization GO:0007338 3 0.043
regionalization GO:0003002 274 0.043
autophagy GO:0006914 4 0.042
regulation of hormone secretion GO:0046883 2 0.042
protein localization to nucleus GO:0034504 3 0.042
establishment of protein localization to organelle GO:0072594 4 0.042
regulation of cellular amine metabolic process GO:0033238 0 0.041
cellular amine metabolic process GO:0044106 2 0.040
neurotransmitter secretion GO:0007269 2 0.040
segmentation GO:0035282 97 0.039
anterior posterior pattern specification GO:0009952 152 0.038
amine metabolic process GO:0009308 2 0.038
negative regulation of secretion GO:0051048 2 0.038
regulation of metal ion transport GO:0010959 4 0.037
single organism metabolic process GO:0044710 217 0.037
endocrine hormone secretion GO:0060986 2 0.036
central nervous system development GO:0007417 387 0.036
transport GO:0006810 220 0.036
peptidyl lysine methylation GO:0018022 3 0.036
multicellular organismal metabolic process GO:0044236 2 0.035
meiotic nuclear division GO:0007126 4 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.034
negative regulation of kinase activity GO:0033673 4 0.033
establishment of localization GO:0051234 244 0.033
macromolecule biosynthetic process GO:0009059 227 0.033
response to uv GO:0009411 3 0.033
regulation of translational initiation GO:0006446 1 0.033
maintenance of location GO:0051235 4 0.032
protein import GO:0017038 3 0.032
regulation of establishment of protein localization GO:0070201 4 0.032
positive regulation of cellular amine metabolic process GO:0033240 0 0.032
positive regulation of secretion by cell GO:1903532 1 0.031
cellular ketone metabolic process GO:0042180 11 0.031
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
negative regulation of protein kinase activity GO:0006469 4 0.031
regulation of cellular ketone metabolic process GO:0010565 7 0.030
single organism transport GO:0044765 206 0.030
phagocytosis GO:0006909 3 0.030
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.030
regulation of cytokine production GO:0001817 3 0.030
regulation of meiotic cell cycle GO:0051445 1 0.030
regulation of intracellular protein transport GO:0033157 3 0.030
stem cell maintenance GO:0019827 4 0.030
regulation of biosynthetic process GO:0009889 250 0.030
regulation of rna metabolic process GO:0051252 224 0.030
biosynthetic process GO:0009058 294 0.029
hormone secretion GO:0046879 2 0.029
positive regulation of cell cycle GO:0045787 3 0.028
neurotransmitter transport GO:0006836 2 0.028
nuclear transport GO:0051169 4 0.028
regulation of chromosome segregation GO:0051983 1 0.027
stem cell proliferation GO:0072089 4 0.027
carboxylic acid metabolic process GO:0019752 22 0.027
positive regulation of cellular biosynthetic process GO:0031328 68 0.027
regulation of nitrogen compound metabolic process GO:0051171 251 0.027
organic cyclic compound metabolic process GO:1901360 301 0.027
Worm
sensory organ development GO:0007423 393 0.026
single organism nuclear import GO:1902593 3 0.026
rna metabolic process GO:0016070 219 0.026
Worm
nuclear migration GO:0007097 3 0.026
organelle organization GO:0006996 227 0.026
positive regulation of translation GO:0045727 1 0.026
regulation of stem cell proliferation GO:0072091 2 0.025
cellular amino acid metabolic process GO:0006520 7 0.025
head development GO:0060322 303 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.025
organic substance biosynthetic process GO:1901576 289 0.025
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.025
stem cell development GO:0048864 82 0.025
stem cell differentiation GO:0048863 117 0.025
meiotic cell cycle process GO:1903046 3 0.025
cellular response to external stimulus GO:0071496 2 0.025
regulation of protein transport GO:0051223 3 0.025
aromatic compound biosynthetic process GO:0019438 217 0.024
skeletal system development GO:0001501 181 0.024
translational initiation GO:0006413 3 0.024
nucleocytoplasmic transport GO:0006913 4 0.024
somitogenesis GO:0001756 87 0.024
protein localization to plasma membrane GO:0072659 1 0.024
embryo development ending in birth or egg hatching GO:0009792 271 0.024
nuclear import GO:0051170 3 0.024
regulation of synapse organization GO:0050807 3 0.023
single organism localization GO:1902578 225 0.023
mrna metabolic process GO:0016071 20 0.023
Worm
cellular amide metabolic process GO:0043603 4 0.023
regulation of cytoplasmic transport GO:1903649 4 0.023
multicellular organism growth GO:0035264 4 0.023
cellular lipid metabolic process GO:0044255 36 0.023
primary neural tube formation GO:0014020 1 0.023
renal system development GO:0072001 94 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
nucleic acid metabolic process GO:0090304 244 0.023
Worm
meiotic chromosome segregation GO:0045132 3 0.022
embryonic organ development GO:0048568 381 0.022
oxoacid metabolic process GO:0043436 31 0.022
digestive system development GO:0055123 289 0.022
secondary metabolic process GO:0019748 3 0.022
regulation of metabolic process GO:0019222 359 0.022
protein import into nucleus GO:0006606 3 0.022
organic acid metabolic process GO:0006082 31 0.022
regulation of developmental process GO:0050793 247 0.022
determination of left right symmetry GO:0007368 179 0.022
endosomal transport GO:0016197 2 0.022
peptidyl threonine phosphorylation GO:0018107 1 0.021
endocrine process GO:0050886 2 0.021
nitrogen compound metabolic process GO:0006807 319 0.021
Worm
cellular protein metabolic process GO:0044267 129 0.021
protein metabolic process GO:0019538 183 0.021
g2 dna damage checkpoint GO:0031572 3 0.021
signal transduction GO:0007165 455 0.021
rna biosynthetic process GO:0032774 181 0.021
regulation of cellular metabolic process GO:0031323 320 0.020
regulation of endocrine process GO:0044060 2 0.020
exocytosis GO:0006887 1 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.020
system process GO:0003008 185 0.020
protein targeting to nucleus GO:0044744 3 0.020
vacuolar transport GO:0007034 2 0.020
regulation of biomineral tissue development GO:0070167 2 0.020
gene expression GO:0010467 252 0.020
response to drug GO:0042493 3 0.020
positive regulation of secretion GO:0051047 1 0.020
cellular response to nutrient levels GO:0031669 2 0.020
tube morphogenesis GO:0035239 349 0.019
ear development GO:0043583 127 0.019
transcription dna templated GO:0006351 181 0.019
positive regulation of apoptotic signaling pathway GO:2001235 1 0.019
cellular component disassembly GO:0022411 1 0.019
cell projection organization GO:0030030 284 0.019
regulation of jak stat cascade GO:0046425 3 0.019
response to oxygen radical GO:0000305 2 0.019
peptide metabolic process GO:0006518 1 0.019
regulation of protein targeting GO:1903533 2 0.019
regulation of reproductive process GO:2000241 4 0.019
cellular component morphogenesis GO:0032989 336 0.019
regulation of embryonic development GO:0045995 47 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.019
positive regulation of protein complex assembly GO:0031334 2 0.019
mesenchymal cell differentiation GO:0048762 87 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.019
negative regulation of dna metabolic process GO:0051053 4 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.018
negative regulation of biological process GO:0048519 304 0.018
regulation of protein catabolic process GO:0042176 1 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
hormone transport GO:0009914 2 0.018
tube closure GO:0060606 1 0.018
cell migration GO:0016477 237 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.018
positive regulation of jnk cascade GO:0046330 3 0.018
positive regulation of stem cell proliferation GO:2000648 1 0.018
regulation of dna replication GO:0006275 3 0.018
camera type eye development GO:0043010 222 0.018
somite development GO:0061053 96 0.018
positive regulation of biological process GO:0048518 253 0.018
golgi vesicle transport GO:0048193 3 0.018
digestive tract morphogenesis GO:0048546 231 0.018
embryonic limb morphogenesis GO:0030326 2 0.018
mitotic dna integrity checkpoint GO:0044774 4 0.018
cellular macromolecule metabolic process GO:0044260 391 0.018
Worm
regulation of protein ubiquitination GO:0031396 3 0.018
regulation of cell differentiation GO:0045595 142 0.018
response to nutrient GO:0007584 3 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
establishment of rna localization GO:0051236 3 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
determination of bilateral symmetry GO:0009855 204 0.017
lipid metabolic process GO:0006629 52 0.017
antimicrobial humoral response GO:0019730 2 0.017
regulation of synaptic plasticity GO:0048167 1 0.017
interspecies interaction between organisms GO:0044419 4 0.017
regulation of binding GO:0051098 3 0.017
membrane fusion GO:0061025 2 0.017
regulation of transcription dna templated GO:0006355 213 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
negative regulation of dna replication GO:0008156 2 0.016
gastrulation GO:0007369 208 0.016
protein stabilization GO:0050821 2 0.016
response to glucose GO:0009749 3 0.016
protein dephosphorylation GO:0006470 3 0.016
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
epithelial tube morphogenesis GO:0060562 148 0.016
activation of mapk activity GO:0000187 3 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
response to stress GO:0006950 263 0.016
nuclear export GO:0051168 1 0.016
odontogenesis of dentin containing tooth GO:0042475 1 0.016
adherens junction organization GO:0034332 4 0.016
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.016
positive regulation of catabolic process GO:0009896 4 0.016
developmental growth GO:0048589 166 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
negative regulation of epithelial cell proliferation GO:0050680 1 0.016
regulation of epithelial cell proliferation GO:0050678 3 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
hemopoiesis GO:0030097 183 0.015
protein complex disassembly GO:0043241 1 0.015
neural crest cell differentiation GO:0014033 72 0.015
negative regulation of map kinase activity GO:0043407 2 0.015
long chain fatty acid metabolic process GO:0001676 1 0.015
atp catabolic process GO:0006200 4 0.015
small molecule metabolic process GO:0044281 77 0.015
regulation of synapse assembly GO:0051963 3 0.015
vasculature development GO:0001944 278 0.015
cellular protein modification process GO:0006464 100 0.015
muscle structure development GO:0061061 196 0.015
cell substrate adhesion GO:0031589 4 0.015
organonitrogen compound metabolic process GO:1901564 74 0.015
regulation of gene expression GO:0010468 265 0.015
phosphorus metabolic process GO:0006793 109 0.015
sister chromatid cohesion GO:0007062 2 0.015
stem cell division GO:0017145 1 0.015
positive regulation of stress activated mapk cascade GO:0032874 3 0.015
heart development GO:0007507 313 0.015
positive regulation of epithelial cell proliferation GO:0050679 1 0.015
cell proliferation GO:0008283 80 0.015
response to corticosteroid GO:0031960 1 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
negative regulation of hormone secretion GO:0046888 2 0.015
heterocycle biosynthetic process GO:0018130 215 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
tissue remodeling GO:0048771 4 0.014
macromolecular complex disassembly GO:0032984 1 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
histone h4 k20 methylation GO:0034770 2 0.014
regulation of dendrite development GO:0050773 3 0.014
sensory organ morphogenesis GO:0090596 200 0.014
negative regulation of secretion by cell GO:1903531 2 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
regulation of cell activation GO:0050865 1 0.014
peptidyl serine modification GO:0018209 2 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
single organism organelle organization GO:1902589 199 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
connective tissue development GO:0061448 99 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
brain development GO:0007420 293 0.014
regulation of primary metabolic process GO:0080090 311 0.014
positive regulation of cellular process GO:0048522 201 0.014
regulation of production of molecular mediator of immune response GO:0002700 1 0.014
cellular response to starvation GO:0009267 1 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
eye development GO:0001654 277 0.013
regulation of cell communication GO:0010646 232 0.013
positive regulation of cell adhesion GO:0045785 1 0.013
mitochondrion organization GO:0007005 4 0.013
peptide transport GO:0015833 1 0.013
cartilage development GO:0051216 96 0.013
regulation of response to stimulus GO:0048583 269 0.013
positive regulation of biosynthetic process GO:0009891 68 0.013
mitotic dna damage checkpoint GO:0044773 4 0.013
regulation of signaling GO:0023051 235 0.013
cilium morphogenesis GO:0060271 85 0.013
retina development in camera type eye GO:0060041 146 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
eye morphogenesis GO:0048592 144 0.013
rna catabolic process GO:0006401 7 0.013
Worm
response to carbohydrate GO:0009743 3 0.013
cognition GO:0050890 1 0.013
negative regulation of stem cell differentiation GO:2000737 2 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
steroid hormone secretion GO:0035929 1 0.013
chemosensory behavior GO:0007635 1 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.013
immune system development GO:0002520 191 0.013
cellular component movement GO:0006928 335 0.013
regulation of response to biotic stimulus GO:0002831 2 0.013
mesenchymal cell development GO:0014031 78 0.013
regulation of protein complex assembly GO:0043254 3 0.013
regulation of transmembrane transporter activity GO:0022898 2 0.013
macromolecule modification GO:0043412 111 0.013
negative regulation of nuclear division GO:0051784 3 0.013
negative regulation of gene expression GO:0010629 65 0.013
membrane invagination GO:0010324 1 0.013
glucose homeostasis GO:0042593 1 0.013
positive regulation of multi organism process GO:0043902 3 0.013
regulation of protein complex disassembly GO:0043244 1 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.012
multi organism cellular process GO:0044764 2 0.012
female sex differentiation GO:0046660 4 0.012
regulation of signal transduction GO:0009966 225 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.012
female gonad development GO:0008585 4 0.012
cellular protein catabolic process GO:0044257 4 0.012
regulation of cell death GO:0010941 103 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
death GO:0016265 121 0.012
rna localization GO:0006403 4 0.012
regulation of systemic arterial blood pressure GO:0003073 1 0.012
neuroblast proliferation GO:0007405 2 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
pronuclear migration GO:0035046 1 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
nucleobase containing compound metabolic process GO:0006139 274 0.012
Worm
response to organic substance GO:0010033 153 0.012
lateral inhibition GO:0046331 1 0.012
nucleobase containing compound transport GO:0015931 2 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
cell death GO:0008219 121 0.012
regulation of mrna processing GO:0050684 3 0.012
localization of cell GO:0051674 244 0.012
negative regulation of cellular metabolic process GO:0031324 77 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
neuron projection development GO:0031175 180 0.012
digestive tract development GO:0048565 265 0.012
adult behavior GO:0030534 2 0.012
b cell activation GO:0042113 2 0.012
gtp metabolic process GO:0046039 4 0.012
organelle fusion GO:0048284 3 0.012
negative regulation of protein import into nucleus GO:0042308 2 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
carbohydrate homeostasis GO:0033500 1 0.011
striated muscle cell differentiation GO:0051146 129 0.011
rna polyadenylation GO:0043631 2 0.011
pathway restricted smad protein phosphorylation GO:0060389 1 0.011
regulation of lipid transport GO:0032368 4 0.011
regulation of organ growth GO:0046620 3 0.011
response to superoxide GO:0000303 2 0.011
meiosis i GO:0007127 1 0.011
cilium organization GO:0044782 71 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
cytoskeleton organization GO:0007010 96 0.011
dna metabolic process GO:0006259 27 0.011
negative regulation of biosynthetic process GO:0009890 55 0.011
protein heterooligomerization GO:0051291 1 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
alternative mrna splicing via spliceosome GO:0000380 1 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
cell matrix adhesion GO:0007160 4 0.011
regulation of programmed cell death GO:0043067 101 0.011
negative regulation of cytokine production GO:0001818 1 0.011
protein demethylation GO:0006482 2 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
negative regulation of myeloid cell differentiation GO:0045638 1 0.011
regulation of bone mineralization GO:0030500 2 0.011
sensory perception of pain GO:0019233 1 0.011
gtp catabolic process GO:0006184 2 0.011
muscle system process GO:0003012 20 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
positive regulation of protein polymerization GO:0032273 2 0.011
kidney development GO:0001822 92 0.011
microtubule based process GO:0007017 60 0.011
regulation of blood vessel size GO:0050880 2 0.011
cell part morphogenesis GO:0032990 246 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
cellular response to oxygen levels GO:0071453 1 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
mitotic g2 m transition checkpoint GO:0044818 3 0.011
positive regulation of immune effector process GO:0002699 3 0.011
multicellular organismal macromolecule metabolic process GO:0044259 2 0.011
regulation of lipase activity GO:0060191 2 0.011
regulation of transporter activity GO:0032409 2 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
histone h3 k4 methylation GO:0051568 2 0.011
macroautophagy GO:0016236 1 0.010
negative regulation of macromolecule metabolic process GO:0010605 76 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
i kappab kinase nf kappab signaling GO:0007249 4 0.010
myeloid cell differentiation GO:0030099 86 0.010
negative regulation of neural precursor cell proliferation GO:2000178 1 0.010
regulation of histone methylation GO:0031060 3 0.010
regulation of multicellular organism growth GO:0040014 4 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
neuromuscular synaptic transmission GO:0007274 2 0.010
mesenchymal cell proliferation GO:0010463 1 0.010
viral process GO:0016032 1 0.010
cell morphogenesis GO:0000902 289 0.010
spermatid differentiation GO:0048515 2 0.010
ameboidal type cell migration GO:0001667 143 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.010
muscle contraction GO:0006936 18 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
lymphatic endothelial cell differentiation GO:0060836 1 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
regulation of biological quality GO:0065008 263 0.010
negative regulation of leukocyte differentiation GO:1902106 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
positive regulation of cell activation GO:0050867 1 0.010

upf3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
disease of metabolism DOID:0014667 0 0.023
musculoskeletal system disease DOID:17 0 0.022
immune system disease DOID:2914 0 0.015
inherited metabolic disorder DOID:655 0 0.014
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.011
cardiovascular system disease DOID:1287 0 0.010