Danio rerio

0 known processes

upf3a

UPF3 regulator of nonsense transcripts homolog A (yeast)

(Aliases: si:dkey-21o13.6)

upf3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.151
Worm
gtp metabolic process GO:0046039 4 0.098
nitrogen compound metabolic process GO:0006807 319 0.089
Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.085
Worm
rna metabolic process GO:0016070 219 0.085
Worm
organic substance biosynthetic process GO:1901576 289 0.076
Human
larval development GO:0002164 2 0.069
aging GO:0007568 2 0.062
cellular aromatic compound metabolic process GO:0006725 295 0.057
Worm
locomotion GO:0040011 313 0.056
cell projection organization GO:0030030 284 0.052
heterocycle metabolic process GO:0046483 290 0.052
Worm
guanosine containing compound metabolic process GO:1901068 4 0.051
organic cyclic compound metabolic process GO:1901360 301 0.051
Worm
guanosine containing compound catabolic process GO:1901069 2 0.050
single organism metabolic process GO:0044710 217 0.046
signal transduction GO:0007165 455 0.043
cellular component assembly GO:0022607 170 0.041
transport GO:0006810 220 0.041
cellular macromolecule metabolic process GO:0044260 391 0.040
Human Worm
gtp catabolic process GO:0006184 2 0.040
cellular component movement GO:0006928 335 0.040
rna catabolic process GO:0006401 7 0.039
Worm
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.038
determination of bilateral symmetry GO:0009855 204 0.038
cellular nitrogen compound catabolic process GO:0044270 15 0.038
Worm
nucleobase containing compound metabolic process GO:0006139 274 0.037
Worm
biosynthetic process GO:0009058 294 0.035
Human
macromolecule biosynthetic process GO:0009059 227 0.035
Human
phosphate containing compound metabolic process GO:0006796 108 0.035
nucleoside monophosphate catabolic process GO:0009125 4 0.035
sensory organ development GO:0007423 393 0.034
specification of symmetry GO:0009799 204 0.034
maintenance of location GO:0051235 4 0.034
positive regulation of transport GO:0051050 2 0.034
cell surface receptor signaling pathway GO:0007166 325 0.033
regionalization GO:0003002 274 0.033
synaptic growth at neuromuscular junction GO:0051124 2 0.033
cellular response to lipopolysaccharide GO:0071222 3 0.033
establishment of localization GO:0051234 244 0.033
small molecule metabolic process GO:0044281 77 0.033
multicellular organism growth GO:0035264 4 0.032
positive regulation of nucleoside metabolic process GO:0045979 1 0.031
nucleic acid metabolic process GO:0090304 244 0.031
Worm
negative regulation of biological process GO:0048519 304 0.030
regulation of nucleotide catabolic process GO:0030811 2 0.030
regulation of purine nucleotide catabolic process GO:0033121 2 0.030
phosphorus metabolic process GO:0006793 109 0.030
cellular macromolecule biosynthetic process GO:0034645 224 0.030
Human
phagocytosis GO:0006909 3 0.029
embryonic organ development GO:0048568 381 0.029
cellular component biogenesis GO:0044085 178 0.029
regulation of macromolecule metabolic process GO:0060255 317 0.028
Human
positive regulation of cellular catabolic process GO:0031331 3 0.027
response to chemical GO:0042221 320 0.027
muscle structure development GO:0061061 196 0.027
single organism localization GO:1902578 225 0.027
single organism transport GO:0044765 206 0.027
cellular response to external stimulus GO:0071496 2 0.027
regulation of multicellular organismal development GO:2000026 223 0.027
heterocycle biosynthetic process GO:0018130 215 0.027
apoptotic process involved in development GO:1902742 2 0.026
chordate embryonic development GO:0043009 271 0.026
regulation of response to stimulus GO:0048583 269 0.026
regulation of gene expression GO:0010468 265 0.025
Human
stem cell maintenance GO:0019827 4 0.025
aromatic compound catabolic process GO:0019439 15 0.025
Worm
regulation of metabolic process GO:0019222 359 0.025
Human
regulation of reproductive process GO:2000241 4 0.025
heart development GO:0007507 313 0.025
regulation of nucleoside metabolic process GO:0009118 2 0.025
regulation of developmental process GO:0050793 247 0.025
organic cyclic compound catabolic process GO:1901361 15 0.025
Worm
cellular amine metabolic process GO:0044106 2 0.024
determination of left right symmetry GO:0007368 179 0.024
transmembrane transport GO:0055085 120 0.024
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.024
organelle fusion GO:0048284 3 0.024
regulation of synapse organization GO:0050807 3 0.024
cellular response to nutrient levels GO:0031669 2 0.024
regulation of signal transduction GO:0009966 225 0.023
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
cilium organization GO:0044782 71 0.023
localization of cell GO:0051674 244 0.023
retina development in camera type eye GO:0060041 146 0.023
cellular catabolic process GO:0044248 27 0.023
Worm
positive regulation of catabolic process GO:0009896 4 0.023
dorsal ventral pattern formation GO:0009953 125 0.023
response to stress GO:0006950 263 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
eye development GO:0001654 277 0.022
regulation of multicellular organismal process GO:0051239 277 0.022
neuron differentiation GO:0030182 353 0.022
response to external stimulus GO:0009605 264 0.022
hormone secretion GO:0046879 2 0.021
regulation of binding GO:0051098 3 0.021
ribonucleoside monophosphate catabolic process GO:0009158 4 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
peptidyl serine phosphorylation GO:0018105 1 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
protein localization to nucleus GO:0034504 3 0.020
neurotransmitter transport GO:0006836 2 0.020
embryonic organ morphogenesis GO:0048562 274 0.020
cellular response to molecule of bacterial origin GO:0071219 3 0.020
single organism membrane fusion GO:0044801 2 0.020
regulation of gtp catabolic process GO:0033124 2 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
protein metabolic process GO:0019538 183 0.020
Human
tube morphogenesis GO:0035239 349 0.020
embryonic limb morphogenesis GO:0030326 2 0.020
response to carbohydrate GO:0009743 3 0.020
regulation of synapse assembly GO:0051963 3 0.020
transcription dna templated GO:0006351 181 0.020
positive regulation of nucleotide catabolic process GO:0030813 1 0.019
microtubule based process GO:0007017 60 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.019
generation of neurons GO:0048699 385 0.019
regulation of dendrite development GO:0050773 3 0.019
membrane fusion GO:0061025 2 0.019
lipid storage GO:0019915 1 0.019
purine nucleoside monophosphate catabolic process GO:0009128 4 0.019
cellular component disassembly GO:0022411 1 0.019
camera type eye development GO:0043010 222 0.019
carboxylic acid metabolic process GO:0019752 22 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
Human
single organism organelle organization GO:1902589 199 0.018
system process GO:0003008 185 0.018
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
oxoacid metabolic process GO:0043436 31 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
hepaticobiliary system development GO:0061008 98 0.018
regulation of cellular metabolic process GO:0031323 320 0.018
Human
atp catabolic process GO:0006200 4 0.018
response to glucose GO:0009749 3 0.018
gland development GO:0048732 143 0.018
peptidyl serine modification GO:0018209 2 0.018
regulation of bmp signaling pathway GO:0030510 39 0.018
apoptotic process GO:0006915 116 0.018
regulation of cytokine production GO:0001817 3 0.018
skeletal system development GO:0001501 181 0.018
positive regulation of biological process GO:0048518 253 0.018
Human
response to topologically incorrect protein GO:0035966 2 0.017
regulation of gtpase activity GO:0043087 2 0.017
negative regulation of cellular process GO:0048523 283 0.017
adult behavior GO:0030534 2 0.017
autophagy GO:0006914 4 0.017
cellular nitrogen compound biosynthetic process GO:0044271 218 0.017
endocrine process GO:0050886 2 0.017
cellular protein catabolic process GO:0044257 4 0.017
cellular biosynthetic process GO:0044249 286 0.017
Human
renal system development GO:0072001 94 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
regulation of primary metabolic process GO:0080090 311 0.017
Human
bmp signaling pathway GO:0030509 52 0.017
negative regulation of reproductive process GO:2000242 3 0.016
cellular component morphogenesis GO:0032989 336 0.016
cellular response to biotic stimulus GO:0071216 3 0.016
nucleic acid templated transcription GO:0097659 181 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
stem cell proliferation GO:0072089 4 0.016
digestive tract development GO:0048565 265 0.016
cilium assembly GO:0042384 58 0.016
amine metabolic process GO:0009308 2 0.016
regulation of biosynthetic process GO:0009889 250 0.016
Human
exocytosis GO:0006887 1 0.016
phototransduction GO:0007602 2 0.016
mesenchyme development GO:0060485 127 0.016
positive regulation of cell cycle GO:0045787 3 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
epithelial cell differentiation GO:0030855 116 0.016
growth GO:0040007 174 0.016
modification dependent protein catabolic process GO:0019941 3 0.016
tissue remodeling GO:0048771 4 0.016
germ line stem cell maintenance GO:0030718 2 0.015
neuron development GO:0048666 262 0.015
regulation of neurotransmitter secretion GO:0046928 1 0.015
sensory perception of chemical stimulus GO:0007606 3 0.015
digestive tract morphogenesis GO:0048546 231 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
rna transport GO:0050658 2 0.015
negative regulation of stem cell differentiation GO:2000737 2 0.015
cellular macromolecule catabolic process GO:0044265 12 0.015
Worm
macromolecular complex disassembly GO:0032984 1 0.015
regulation of cell communication GO:0010646 232 0.015
mesenchymal cell differentiation GO:0048762 87 0.015
gene expression GO:0010467 252 0.015
Human
regulation of biological quality GO:0065008 263 0.015
positive regulation of gtp catabolic process GO:0033126 1 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
lipid metabolic process GO:0006629 52 0.015
embryonic skeletal system development GO:0048706 97 0.015
eye morphogenesis GO:0048592 144 0.015
rna localization GO:0006403 4 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.015
cellular protein metabolic process GO:0044267 129 0.015
Human
cell morphogenesis GO:0000902 289 0.015
secondary metabolic process GO:0019748 3 0.015
meiotic nuclear division GO:0007126 4 0.015
connective tissue development GO:0061448 99 0.015
neurotransmitter secretion GO:0007269 2 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
ion transmembrane transport GO:0034220 91 0.014
apoptotic process involved in morphogenesis GO:0060561 2 0.014
cellular ketone metabolic process GO:0042180 11 0.014
regulation of signaling GO:0023051 235 0.014
ribosomal small subunit biogenesis GO:0042274 2 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
negative regulation of kinase activity GO:0033673 4 0.014
muscle organ development GO:0007517 101 0.014
primary neural tube formation GO:0014020 1 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
tube closure GO:0060606 1 0.014
response to monosaccharide GO:0034284 3 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
regulation of cell shape GO:0008360 1 0.014
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.014
regulation of neurotransmitter transport GO:0051588 1 0.014
interspecies interaction between organisms GO:0044419 4 0.014
cell projection morphogenesis GO:0048858 244 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
positive regulation of secretion GO:0051047 1 0.014
regulation of exocytosis GO:0017157 1 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
neural crest cell differentiation GO:0014033 72 0.014
regulation of sequestering of calcium ion GO:0051282 4 0.014
nuclear import GO:0051170 3 0.014
cell motility GO:0048870 244 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
glomerulus development GO:0032835 27 0.013
somatic stem cell maintenance GO:0035019 1 0.013
odontogenesis of dentin containing tooth GO:0042475 1 0.013
cilium morphogenesis GO:0060271 85 0.013
regulation of chondrocyte differentiation GO:0032330 1 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
cellular protein modification process GO:0006464 100 0.013
centrosome organization GO:0051297 1 0.013
endosomal transport GO:0016197 2 0.013
regulation of rna metabolic process GO:0051252 224 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.013
compound eye development GO:0048749 2 0.013
establishment of rna localization GO:0051236 3 0.013
protein import into nucleus GO:0006606 3 0.013
developmental programmed cell death GO:0010623 4 0.013
positive regulation of translation GO:0045727 1 0.013
Human
mitochondrion organization GO:0007005 4 0.013
digestive system development GO:0055123 289 0.013
organelle organization GO:0006996 227 0.013
response to organic substance GO:0010033 153 0.013
synaptic target recognition GO:0008039 1 0.013
golgi vesicle transport GO:0048193 3 0.013
mrna catabolic process GO:0006402 6 0.013
Worm
regulation of circadian rhythm GO:0042752 4 0.013
microtubule based movement GO:0007018 33 0.013
regulation of cell activation GO:0050865 1 0.013
cellular response to organic substance GO:0071310 105 0.013
macromolecule modification GO:0043412 111 0.013
protein dephosphorylation GO:0006470 3 0.013
cellular lipid metabolic process GO:0044255 36 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
striated muscle cell differentiation GO:0051146 129 0.013
protein homooligomerization GO:0051260 3 0.013
peptide transport GO:0015833 1 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
chemosensory behavior GO:0007635 1 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
neuron projection development GO:0031175 180 0.012
protein stabilization GO:0050821 2 0.012
mrna metabolic process GO:0016071 20 0.012
Worm
proteasomal protein catabolic process GO:0010498 2 0.012
negative regulation of metabolic process GO:0009892 86 0.012
regulation of hormone secretion GO:0046883 2 0.012
organic acid metabolic process GO:0006082 31 0.012
cell part morphogenesis GO:0032990 246 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
response to alkaloid GO:0043279 2 0.012
inner ear development GO:0048839 126 0.012
nucleic acid transport GO:0050657 2 0.012
negative regulation of cytokine production GO:0001818 1 0.012
regulation of membrane potential GO:0042391 23 0.012
regulation of nervous system development GO:0051960 90 0.012
macroautophagy GO:0016236 1 0.012
nucleocytoplasmic transport GO:0006913 4 0.012
cellular response to starvation GO:0009267 1 0.012
hatching GO:0035188 4 0.012
cartilage development GO:0051216 96 0.012
regulation of cell differentiation GO:0045595 142 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
cell projection assembly GO:0030031 64 0.012
positive regulation of metabolic process GO:0009893 108 0.012
Human
neural crest cell migration GO:0001755 42 0.012
lateral inhibition GO:0046331 1 0.012
regulation of jak stat cascade GO:0046425 3 0.012
embryonic skeletal joint development GO:0072498 3 0.012
regulation of protein transport GO:0051223 3 0.012
microtubule cytoskeleton organization GO:0000226 33 0.012
carbohydrate homeostasis GO:0033500 1 0.012
cytoskeleton organization GO:0007010 96 0.012
negative regulation of map kinase activity GO:0043407 2 0.012
urogenital system development GO:0001655 97 0.012
organelle assembly GO:0070925 110 0.012
cell migration GO:0016477 237 0.011
cellular response to radiation GO:0071478 4 0.011
multicellular organismal signaling GO:0035637 22 0.011
action potential GO:0001508 19 0.011
gastrulation GO:0007369 208 0.011
transmission of nerve impulse GO:0019226 19 0.011
cellular response to xenobiotic stimulus GO:0071466 35 0.011
heart morphogenesis GO:0003007 156 0.011
melanin metabolic process GO:0006582 2 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
cellular localization GO:0051641 97 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
membrane invagination GO:0010324 1 0.011
regulation of protein catabolic process GO:0042176 1 0.011
protein modification process GO:0036211 100 0.011
response to uv GO:0009411 3 0.011
regulation of endocrine process GO:0044060 2 0.011
g2 m transition of mitotic cell cycle GO:0000086 4 0.011
regulation of protein complex assembly GO:0043254 3 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
meiotic cell cycle process GO:1903046 3 0.011
protein complex assembly GO:0006461 30 0.011
kidney development GO:0001822 92 0.011
regulation of dendrite morphogenesis GO:0048814 3 0.011
ear development GO:0043583 127 0.011
protein complex subunit organization GO:0071822 46 0.011
nephron morphogenesis GO:0072028 2 0.011
cardiac atrium development GO:0003230 4 0.011
regulation of heart growth GO:0060420 2 0.011
endocrine hormone secretion GO:0060986 2 0.011
pathway restricted smad protein phosphorylation GO:0060389 1 0.011
carbohydrate derivative metabolic process GO:1901135 61 0.011
regulation of transcription dna templated GO:0006355 213 0.011
nucleobase containing compound transport GO:0015931 2 0.011
single fertilization GO:0007338 3 0.011
protein localization to plasma membrane GO:0072659 1 0.011
hormone transport GO:0009914 2 0.011
macromolecule catabolic process GO:0009057 15 0.011
Worm
negative regulation of catabolic process GO:0009895 3 0.011
neural crest cell development GO:0014032 62 0.011
stem cell differentiation GO:0048863 117 0.011
fin development GO:0033333 77 0.011
developmental growth GO:0048589 166 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
Human
purine containing compound metabolic process GO:0072521 29 0.011
cellular response to light stimulus GO:0071482 4 0.011
regulation of cellular component organization GO:0051128 86 0.011
neuroblast proliferation GO:0007405 2 0.010
brain development GO:0007420 293 0.010
vasculature development GO:0001944 278 0.010
regulation of cellular biosynthetic process GO:0031326 245 0.010
Human
regulation of ion transmembrane transporter activity GO:0032412 2 0.010
protein targeting to nucleus GO:0044744 3 0.010
b cell activation GO:0042113 2 0.010
cellular component assembly involved in morphogenesis GO:0010927 107 0.010
heart looping GO:0001947 94 0.010
neurological system process GO:0050877 62 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
muscle cell differentiation GO:0042692 139 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.010
establishment of synaptic vesicle localization GO:0097480 1 0.010
lamellipodium assembly GO:0030032 1 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
regulation of rna biosynthetic process GO:2001141 213 0.010
regulation of biomineral tissue development GO:0070167 2 0.010
sensory organ morphogenesis GO:0090596 200 0.010
regulation of protein binding GO:0043393 3 0.010
establishment of protein localization to organelle GO:0072594 4 0.010
regulation of organ growth GO:0046620 3 0.010

upf3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
immune system disease DOID:2914 0 0.019
disease of metabolism DOID:0014667 0 0.018
bone disease DOID:0080001 0 0.016
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016
inherited metabolic disorder DOID:655 0 0.010
hematopoietic system disease DOID:74 0 0.010