Danio rerio

0 known processes

eprs

glutamyl-prolyl-tRNA synthetase

(Aliases: wu:fb38d08,wu:ft34d10)

eprs biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.541
Worm
cellular macromolecule metabolic process GO:0044260 391 0.319
Human
embryo development ending in birth or egg hatching GO:0009792 271 0.309
Worm
aging GO:0007568 2 0.242
cellular amino acid metabolic process GO:0006520 7 0.185
cell cell recognition GO:0009988 1 0.181
organic substance biosynthetic process GO:1901576 289 0.172
Human
regulation of gtp catabolic process GO:0033124 2 0.161
transport GO:0006810 220 0.159
positive regulation of catabolic process GO:0009896 4 0.158
single fertilization GO:0007338 3 0.150
establishment of localization GO:0051234 244 0.145
single organism metabolic process GO:0044710 217 0.144
regulation of multicellular organismal process GO:0051239 277 0.142
small molecule metabolic process GO:0044281 77 0.132
fertilization GO:0009566 3 0.131
cellular protein metabolic process GO:0044267 129 0.120
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.120
Human
organic cyclic compound metabolic process GO:1901360 301 0.119
regulation of biological quality GO:0065008 263 0.112
guanosine containing compound metabolic process GO:1901068 4 0.112
locomotion GO:0040011 313 0.111
positive regulation of biological process GO:0048518 253 0.109
cytokinesis GO:0000910 3 0.109
protein metabolic process GO:0019538 183 0.103
Human
organonitrogen compound metabolic process GO:1901564 74 0.101
positive regulation of cellular catabolic process GO:0031331 3 0.100
apoptotic process GO:0006915 116 0.097
biosynthetic process GO:0009058 294 0.097
Human
regulation of protein complex assembly GO:0043254 3 0.094
spindle assembly GO:0051225 2 0.093
programmed cell death GO:0012501 119 0.092
central nervous system development GO:0007417 387 0.086
oxoacid metabolic process GO:0043436 31 0.083
maintenance of location GO:0051235 4 0.083
lipid storage GO:0019915 1 0.078
cell death GO:0008219 121 0.074
response to topologically incorrect protein GO:0035966 2 0.074
gtp metabolic process GO:0046039 4 0.072
cellular protein catabolic process GO:0044257 4 0.070
gene expression GO:0010467 252 0.070
Human
regulation of protein catabolic process GO:0042176 1 0.069
gtp catabolic process GO:0006184 2 0.068
toxin transport GO:1901998 2 0.067
regulation of multicellular organism growth GO:0040014 4 0.066
regulation of purine nucleotide catabolic process GO:0033121 2 0.066
death GO:0016265 121 0.066
translation GO:0006412 5 0.065
Human
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.064
multicellular organism growth GO:0035264 4 0.061
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.061
carboxylic acid metabolic process GO:0019752 22 0.061
nitrogen compound metabolic process GO:0006807 319 0.060
cellular biosynthetic process GO:0044249 286 0.060
Human
response to amino acid GO:0043200 2 0.057
microtubule organizing center organization GO:0031023 1 0.055
regulation of nucleoside metabolic process GO:0009118 2 0.055
positive regulation of gtp catabolic process GO:0033126 1 0.054
translational initiation GO:0006413 3 0.054
guanosine containing compound catabolic process GO:1901069 2 0.054
heterocycle metabolic process GO:0046483 290 0.053
nucleobase containing compound metabolic process GO:0006139 274 0.051
generation of neurons GO:0048699 385 0.051
positive regulation of cellular component biogenesis GO:0044089 3 0.050
nucleic acid metabolic process GO:0090304 244 0.049
growth GO:0040007 174 0.048
protein complex disassembly GO:0043241 1 0.048
regulation of nucleotide catabolic process GO:0030811 2 0.047
ncrna metabolic process GO:0034660 12 0.046
neuron differentiation GO:0030182 353 0.046
modification dependent macromolecule catabolic process GO:0043632 3 0.046
cellular nitrogen compound metabolic process GO:0034641 290 0.044
phagocytosis GO:0006909 3 0.044
regulation of metabolic process GO:0019222 359 0.044
Human
glial cell differentiation GO:0010001 42 0.044
positive regulation of protein complex assembly GO:0031334 2 0.043
nucleobase containing compound biosynthetic process GO:0034654 205 0.043
positive regulation of gtpase activity GO:0043547 1 0.043
regulation of gtpase activity GO:0043087 2 0.043
female gonad development GO:0008585 4 0.042
organic acid metabolic process GO:0006082 31 0.041
regulation of cellular metabolic process GO:0031323 320 0.040
Human
cellular component disassembly GO:0022411 1 0.038
head development GO:0060322 303 0.037
embryonic organ development GO:0048568 381 0.037
ovulation cycle GO:0042698 2 0.037
cell morphogenesis GO:0000902 289 0.035
regulation of establishment of protein localization GO:0070201 4 0.035
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.034
proteasomal protein catabolic process GO:0010498 2 0.034
protein secretion GO:0009306 1 0.034
cell projection morphogenesis GO:0048858 244 0.034
macromolecule biosynthetic process GO:0009059 227 0.034
Human
cellular response to organic substance GO:0071310 105 0.033
Human
stem cell differentiation GO:0048863 117 0.033
regulation of protein targeting GO:1903533 2 0.032
phosphate containing compound metabolic process GO:0006796 108 0.032
protein import into nucleus GO:0006606 3 0.032
meiotic cell cycle process GO:1903046 3 0.031
cellular response to topologically incorrect protein GO:0035967 2 0.030
positive regulation of nucleoside metabolic process GO:0045979 1 0.030
neuromuscular process controlling balance GO:0050885 3 0.030
single organism localization GO:1902578 225 0.030
protein import GO:0017038 3 0.029
nuclear division GO:0000280 23 0.029
cell part morphogenesis GO:0032990 246 0.029
multi organism process GO:0051704 134 0.029
protein localization to plasma membrane GO:0072659 1 0.029
spindle assembly involved in mitosis GO:0090307 1 0.029
meiotic nuclear division GO:0007126 4 0.029
regulation of protein localization to nucleus GO:1900180 2 0.029
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.028
er nucleus signaling pathway GO:0006984 2 0.028
positive regulation of apoptotic signaling pathway GO:2001235 1 0.028
interaction with host GO:0051701 4 0.028
positive regulation of nucleotide catabolic process GO:0030813 1 0.028
reproduction GO:0000003 40 0.028
digestive tract morphogenesis GO:0048546 231 0.028
response to chemical GO:0042221 320 0.027
Human
lateral inhibition GO:0046331 1 0.027
regionalization GO:0003002 274 0.026
regulation of developmental process GO:0050793 247 0.026
positive regulation of transport GO:0051050 2 0.025
aromatic compound biosynthetic process GO:0019438 217 0.025
ubiquitin dependent protein catabolic process GO:0006511 3 0.025
regulation of primary metabolic process GO:0080090 311 0.025
Human
neuron development GO:0048666 262 0.024
cell cycle GO:0007049 93 0.024
cellular component morphogenesis GO:0032989 336 0.023
protein depolymerization GO:0051261 1 0.023
cellular protein complex disassembly GO:0043624 1 0.023
tube morphogenesis GO:0035239 349 0.022
developmental growth GO:0048589 166 0.022
regulation of protein transport GO:0051223 3 0.021
nuclear import GO:0051170 3 0.021
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.021
chordate embryonic development GO:0043009 271 0.021
regulation of protein binding GO:0043393 3 0.021
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.021
endocytosis GO:0006897 16 0.021
carbohydrate derivative metabolic process GO:1901135 61 0.020
sensory organ development GO:0007423 393 0.020
negative regulation of synapse assembly GO:0051964 2 0.020
response to endogenous stimulus GO:0009719 83 0.020
cell cycle process GO:0022402 53 0.020
regulation of cellular protein catabolic process GO:1903362 1 0.019
cellular response to chemical stimulus GO:0070887 157 0.019
Human
macromolecular complex disassembly GO:0032984 1 0.019
production of molecular mediator of immune response GO:0002440 2 0.019
neuron projection morphogenesis GO:0048812 161 0.019
regulation of transcription dna templated GO:0006355 213 0.018
cellular response to external stimulus GO:0071496 2 0.018
angiogenesis GO:0001525 158 0.018
nucleic acid transport GO:0050657 2 0.018
protein complex subunit organization GO:0071822 46 0.018
regulation of cellular protein metabolic process GO:0032268 52 0.018
Human
negative regulation of macromolecule metabolic process GO:0010605 76 0.018
Human
female sex differentiation GO:0046660 4 0.017
kidney development GO:0001822 92 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
neuromuscular process GO:0050905 7 0.017
regulation of inflammatory response GO:0050727 2 0.017
rna localization GO:0006403 4 0.017
astrocyte differentiation GO:0048708 1 0.017
regulation of programmed cell death GO:0043067 101 0.017
ras protein signal transduction GO:0007265 7 0.017
regulation of cell death GO:0010941 103 0.016
ovarian follicle development GO:0001541 2 0.016
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.016
mitotic cell cycle GO:0000278 64 0.016
protein polymerization GO:0051258 4 0.016
posttranscriptional regulation of gene expression GO:0010608 14 0.016
Human
meiotic spindle organization GO:0000212 1 0.016
mitotic cytokinesis GO:0000281 3 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
response to hexose GO:0009746 3 0.016
brain development GO:0007420 293 0.016
interspecies interaction between organisms GO:0044419 4 0.016
regulation of response to stimulus GO:0048583 269 0.016
dna templated transcription initiation GO:0006352 1 0.016
regulation of apoptotic process GO:0042981 98 0.015
response to alkaloid GO:0043279 2 0.015
taxis GO:0042330 109 0.015
nucleobase containing small molecule metabolic process GO:0055086 32 0.015
cell projection organization GO:0030030 284 0.015
single organism nuclear import GO:1902593 3 0.015
eye development GO:0001654 277 0.015
response to organic substance GO:0010033 153 0.015
Human
response to unfolded protein GO:0006986 2 0.015
regulation of binding GO:0051098 3 0.015
microtubule polymerization GO:0046785 2 0.015
response to carbohydrate GO:0009743 3 0.015
renal system development GO:0072001 94 0.015
fin regeneration GO:0031101 51 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
centrosome organization GO:0051297 1 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
digestive system development GO:0055123 289 0.015
determination of left right symmetry GO:0007368 179 0.015
positive regulation of metabolic process GO:0009893 108 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
response to stress GO:0006950 263 0.014
Human
single organism biosynthetic process GO:0044711 71 0.014
response to glucose GO:0009749 3 0.014
response to monosaccharide GO:0034284 3 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
dna templated transcription elongation GO:0006354 3 0.014
regulation of molecular function GO:0065009 70 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
protein heterooligomerization GO:0051291 1 0.013
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.013
negative regulation of programmed cell death GO:0043069 58 0.013
cranial nerve development GO:0021545 42 0.013
er to golgi vesicle mediated transport GO:0006888 1 0.013
regulation of gene expression GO:0010468 265 0.013
Human
transcription from rna polymerase ii promoter GO:0006366 80 0.013
macroautophagy GO:0016236 1 0.013
multicellular organismal signaling GO:0035637 22 0.013
metencephalon development GO:0022037 27 0.013
cellular component movement GO:0006928 335 0.013
meiotic chromosome segregation GO:0045132 3 0.013
mesenchyme development GO:0060485 127 0.013
regulation of cell communication GO:0010646 232 0.013
cellular ketone metabolic process GO:0042180 11 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
protein targeting to nucleus GO:0044744 3 0.013
mitochondrion organization GO:0007005 4 0.013
cellular response to starvation GO:0009267 1 0.013
regulation of synapse assembly GO:0051963 3 0.012
negative regulation of translation GO:0017148 1 0.012
Human
negative regulation of cell death GO:0060548 60 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
regulation of developmental growth GO:0048638 38 0.012
cellular response to nutrient levels GO:0031669 2 0.012
ion transmembrane transport GO:0034220 91 0.012
specification of symmetry GO:0009799 204 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
mitotic nuclear division GO:0007067 18 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
regulation of organelle assembly GO:1902115 4 0.012
protein modification process GO:0036211 100 0.012
sister chromatid cohesion GO:0007062 2 0.012
developmental process involved in reproduction GO:0003006 27 0.012
somitogenesis GO:0001756 87 0.012
transmission of nerve impulse GO:0019226 19 0.012
protein complex assembly GO:0006461 30 0.012
cell surface receptor signaling pathway GO:0007166 325 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
action potential GO:0001508 19 0.012
organophosphate metabolic process GO:0019637 37 0.012
gliogenesis GO:0042063 45 0.011
regulation of cell shape GO:0008360 1 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
negative regulation of ras protein signal transduction GO:0046580 1 0.011
sensory organ morphogenesis GO:0090596 200 0.011
endoplasmic reticulum unfolded protein response GO:0030968 2 0.011
compound eye development GO:0048749 2 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
regulation of signal transduction GO:0009966 225 0.011
macromolecule modification GO:0043412 111 0.011
embryonic heart tube development GO:0035050 133 0.011
negative regulation of stem cell differentiation GO:2000737 2 0.011
stem cell division GO:0017145 1 0.011
pole plasm assembly GO:0007315 4 0.011
gastrulation GO:0007369 208 0.011
regulation of signaling GO:0023051 235 0.011
protein n linked glycosylation GO:0006487 1 0.011
developmental programmed cell death GO:0010623 4 0.011
immunoglobulin production GO:0002377 1 0.011
signal transduction GO:0007165 455 0.011
cellular response to unfolded protein GO:0034620 2 0.011
convergent extension involved in gastrulation GO:0060027 71 0.011
positive regulation of embryonic development GO:0040019 3 0.011
kupffer s vesicle development GO:0070121 50 0.011
positive regulation of cell activation GO:0050867 1 0.011
digestive tract development GO:0048565 265 0.011
blood vessel morphogenesis GO:0048514 216 0.011
neuron projection development GO:0031175 180 0.010
negative regulation of protein kinase activity GO:0006469 4 0.010
centrosome cycle GO:0007098 1 0.010
embryonic skeletal system development GO:0048706 97 0.010
regulation of purine nucleotide metabolic process GO:1900542 17 0.010
tissue regeneration GO:0042246 74 0.010
negative regulation of cellular process GO:0048523 283 0.010
Human
establishment of protein localization to plasma membrane GO:0090002 1 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
regulation of macromolecule metabolic process GO:0060255 317 0.010
Human
amine metabolic process GO:0009308 2 0.010
positive regulation of developmental process GO:0051094 50 0.010
apoptotic process involved in development GO:1902742 2 0.010
transmembrane transport GO:0055085 120 0.010
nucleobase containing compound transport GO:0015931 2 0.010
membrane fusion GO:0061025 2 0.010
cell cycle g1 s phase transition GO:0044843 1 0.010

eprs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.228
nervous system disease DOID:863 0 0.104
neuromuscular disease DOID:440 0 0.063
charcot marie tooth disease DOID:10595 0 0.063
neuropathy DOID:870 0 0.063
charcot marie tooth disease type 2 DOID:0050539 0 0.027
central nervous system disease DOID:331 0 0.024
neurodegenerative disease DOID:1289 0 0.024
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
myopathy DOID:423 0 0.014
muscular disease DOID:0080000 0 0.014
heart disease DOID:114 0 0.014
cardiomyopathy DOID:0050700 0 0.014
intrinsic cardiomyopathy DOID:0060036 0 0.014
cardiovascular system disease DOID:1287 0 0.014
musculoskeletal system disease DOID:17 0 0.014
muscle tissue disease DOID:66 0 0.014
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011