Danio rerio

0 known processes

aspn

asporin (LRR class 1)

(Aliases: bgl3,aspnl,zgc:109936,wu:fk08c11)

aspn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cartilage development GO:0051216 96 0.187
Zebrafish
embryonic organ development GO:0048568 381 0.164
Zebrafish
cell migration GO:0016477 237 0.159
mesenchymal cell differentiation GO:0048762 87 0.143
response to external stimulus GO:0009605 264 0.140
localization of cell GO:0051674 244 0.135
regulation of metal ion transport GO:0010959 4 0.122
blood vessel morphogenesis GO:0048514 216 0.120
larval development GO:0002164 2 0.114
cellular component movement GO:0006928 335 0.109
heart development GO:0007507 313 0.106
macromolecule biosynthetic process GO:0009059 227 0.103
cell motility GO:0048870 244 0.091
fin development GO:0033333 77 0.089
regulation of cytokine production GO:0001817 3 0.088
skeletal system development GO:0001501 181 0.088
Zebrafish
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.087
cell morphogenesis GO:0000902 289 0.086
nucleoside monophosphate catabolic process GO:0009125 4 0.083
cellular component morphogenesis GO:0032989 336 0.080
cell projection morphogenesis GO:0048858 244 0.078
morphogenesis of an epithelium GO:0002009 333 0.072
Zebrafish
homeostatic process GO:0042592 142 0.071
regulation of biological quality GO:0065008 263 0.067
adult behavior GO:0030534 2 0.066
embryonic skeletal system development GO:0048706 97 0.062
vasculature development GO:0001944 278 0.061
connective tissue development GO:0061448 99 0.060
Zebrafish
endochondral bone growth GO:0003416 2 0.060
positive regulation of cytokine production GO:0001819 2 0.060
regulation of muscle contraction GO:0006937 3 0.059
embryonic skeletal system morphogenesis GO:0048704 93 0.059
nucleobase containing compound biosynthetic process GO:0034654 205 0.057
regulation of nitrogen compound metabolic process GO:0051171 251 0.056
heart morphogenesis GO:0003007 156 0.054
chordate embryonic development GO:0043009 271 0.054
cellular biosynthetic process GO:0044249 286 0.053
sensory organ development GO:0007423 393 0.052
Zebrafish
axonogenesis GO:0007409 152 0.052
cellular macromolecule biosynthetic process GO:0034645 224 0.051
taxis GO:0042330 109 0.049
rna biosynthetic process GO:0032774 181 0.049
nucleic acid templated transcription GO:0097659 181 0.048
cation transport GO:0006812 81 0.048
single organism transport GO:0044765 206 0.048
phagocytosis GO:0006909 3 0.045
aromatic compound biosynthetic process GO:0019438 217 0.045
embryonic organ morphogenesis GO:0048562 274 0.044
Zebrafish
blood vessel development GO:0001568 246 0.044
heart process GO:0003015 71 0.044
response to abiotic stimulus GO:0009628 122 0.042
appendage development GO:0048736 80 0.042
response to topologically incorrect protein GO:0035966 2 0.041
atp catabolic process GO:0006200 4 0.041
angiogenesis GO:0001525 158 0.041
regulation of multicellular organismal process GO:0051239 277 0.041
Mouse
positive regulation of transport GO:0051050 2 0.040
developmental growth GO:0048589 166 0.039
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.039
neural crest cell development GO:0014032 62 0.038
cell projection organization GO:0030030 284 0.038
negative regulation of biological process GO:0048519 304 0.038
Human Mouse
head development GO:0060322 303 0.037
establishment of localization GO:0051234 244 0.036
ribonucleoside monophosphate catabolic process GO:0009158 4 0.035
response to drug GO:0042493 3 0.035
regulation of transmembrane transporter activity GO:0022898 2 0.035
stem cell differentiation GO:0048863 117 0.035
cellular response to external stimulus GO:0071496 2 0.035
neuron differentiation GO:0030182 353 0.035
sensory organ morphogenesis GO:0090596 200 0.034
Zebrafish
digestive tract development GO:0048565 265 0.033
regulation of metabolic process GO:0019222 359 0.033
tissue remodeling GO:0048771 4 0.033
biosynthetic process GO:0009058 294 0.032
specification of symmetry GO:0009799 204 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.032
fin morphogenesis GO:0033334 53 0.032
regulation of ion transmembrane transporter activity GO:0032412 2 0.032
skin development GO:0043588 54 0.031
axon ensheathment in central nervous system GO:0032291 2 0.031
cell part morphogenesis GO:0032990 246 0.031
aging GO:0007568 2 0.031
modification dependent protein catabolic process GO:0019941 3 0.031
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
generation of neurons GO:0048699 385 0.031
regulation of gene expression GO:0010468 265 0.031
regulation of cellular metabolic process GO:0031323 320 0.030
nucleobase containing compound metabolic process GO:0006139 274 0.030
regulation of localization GO:0032879 104 0.030
response to amino acid GO:0043200 2 0.029
regulation of striated muscle contraction GO:0006942 2 0.029
organic cyclic compound biosynthetic process GO:1901362 223 0.029
skeletal system morphogenesis GO:0048705 102 0.029
regulation of transporter activity GO:0032409 2 0.029
appendage morphogenesis GO:0035107 56 0.029
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.029
nitrogen compound metabolic process GO:0006807 319 0.029
Zebrafish
response to oxygen levels GO:0070482 25 0.029
embryo development ending in birth or egg hatching GO:0009792 271 0.029
heterocycle biosynthetic process GO:0018130 215 0.028
organic cyclic compound metabolic process GO:1901360 301 0.028
transport GO:0006810 220 0.028
negative regulation of cellular process GO:0048523 283 0.028
Human Mouse
positive regulation of cellular amine metabolic process GO:0033240 0 0.028
regulation of primary metabolic process GO:0080090 311 0.028
mesenchymal cell development GO:0014031 78 0.027
neuron projection morphogenesis GO:0048812 161 0.027
eye development GO:0001654 277 0.027
Zebrafish
digestive system development GO:0055123 289 0.026
lipid catabolic process GO:0016042 4 0.026
neuron development GO:0048666 262 0.026
organic substance biosynthetic process GO:1901576 289 0.026
cellular response to lipopolysaccharide GO:0071222 3 0.026
cellular response to topologically incorrect protein GO:0035967 2 0.026
muscle cell differentiation GO:0042692 139 0.026
heterocycle metabolic process GO:0046483 290 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.026
blood circulation GO:0008015 87 0.025
regulation of macromolecule biosynthetic process GO:0010556 225 0.025
cellular response to lipid GO:0071396 39 0.025
growth plate cartilage development GO:0003417 2 0.025
regulation of sodium ion transport GO:0002028 2 0.025
response to stress GO:0006950 263 0.025
central nervous system development GO:0007417 387 0.025
positive regulation of biological process GO:0048518 253 0.025
embryonic cranial skeleton morphogenesis GO:0048701 90 0.025
regulation of nucleic acid templated transcription GO:1903506 213 0.025
muscle structure development GO:0061061 196 0.025
axon development GO:0061564 166 0.024
response to chemical GO:0042221 320 0.024
Human Mouse
epidermis development GO:0008544 48 0.023
cellular response to molecule of bacterial origin GO:0071219 3 0.023
regulation of inflammatory response GO:0050727 2 0.023
regulation of cellular biosynthetic process GO:0031326 245 0.023
cellular component assembly involved in morphogenesis GO:0010927 107 0.023
tube morphogenesis GO:0035239 349 0.023
rna metabolic process GO:0016070 219 0.023
endoplasmic reticulum unfolded protein response GO:0030968 2 0.022
organic acid metabolic process GO:0006082 31 0.022
Zebrafish
signal transduction GO:0007165 455 0.022
Human Mouse
nuclear transport GO:0051169 4 0.022
mesenchyme development GO:0060485 127 0.022
production of molecular mediator of immune response GO:0002440 2 0.022
regulation of sequestering of calcium ion GO:0051282 4 0.022
inorganic ion transmembrane transport GO:0098660 57 0.022
regulation of epithelial cell proliferation GO:0050678 3 0.022
multi organism process GO:0051704 134 0.022
striated muscle tissue development GO:0014706 110 0.021
nuclear import GO:0051170 3 0.021
regulation of production of molecular mediator of immune response GO:0002700 1 0.021
purine nucleoside monophosphate catabolic process GO:0009128 4 0.021
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.021
astrocyte differentiation GO:0048708 1 0.021
regulation of membrane potential GO:0042391 23 0.021
er nucleus signaling pathway GO:0006984 2 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
regulation of signal transduction GO:0009966 225 0.020
Human Mouse
extracellular matrix organization GO:0030198 27 0.020
Zebrafish
transmembrane transport GO:0055085 120 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
Zebrafish
mesoderm development GO:0007498 88 0.020
regulation of calcium ion transport GO:0051924 2 0.020
gastrulation GO:0007369 208 0.020
transcription dna templated GO:0006351 181 0.020
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.020
peptidyl serine modification GO:0018209 2 0.020
cellular sodium ion homeostasis GO:0006883 1 0.020
cellular extravasation GO:0045123 1 0.020
regulation of rna metabolic process GO:0051252 224 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
Human Mouse
amine metabolic process GO:0009308 2 0.019
ameboidal type cell migration GO:0001667 143 0.019
meiotic chromosome segregation GO:0045132 3 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.019
protein localization to nucleus GO:0034504 3 0.019
cellular response to organic substance GO:0071310 105 0.019
Human Mouse
growth GO:0040007 174 0.018
Zebrafish
heart contraction GO:0060047 71 0.018
meiotic cell cycle process GO:1903046 3 0.018
immune system process GO:0002376 241 0.018
oxoacid metabolic process GO:0043436 31 0.018
Zebrafish
cellular lipid catabolic process GO:0044242 3 0.018
cell cycle g2 m phase transition GO:0044839 4 0.018
response to unfolded protein GO:0006986 2 0.018
epithelial cell differentiation GO:0030855 116 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
regulation of cellular component movement GO:0051270 55 0.018
positive regulation of catabolic process GO:0009896 4 0.018
regulation of cardiac muscle cell contraction GO:0086004 1 0.018
regionalization GO:0003002 274 0.018
sequestering of calcium ion GO:0051208 3 0.018
nucleic acid metabolic process GO:0090304 244 0.018
circulatory system process GO:0003013 87 0.018
multicellular organism growth GO:0035264 4 0.018
regulation of transmembrane transport GO:0034762 18 0.018
regulation of blood pressure GO:0008217 1 0.018
camera type eye development GO:0043010 222 0.017
Zebrafish
inner ear receptor cell fate commitment GO:0060120 4 0.017
camera type eye morphogenesis GO:0048593 108 0.017
Zebrafish
regulation of biosynthetic process GO:0009889 250 0.017
collagen metabolic process GO:0032963 2 0.017
neural crest cell differentiation GO:0014033 72 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
regulation of cell projection assembly GO:0060491 4 0.017
cardiac muscle cell contraction GO:0086003 1 0.017
regulation of rna biosynthetic process GO:2001141 213 0.017
embryonic viscerocranium morphogenesis GO:0048703 52 0.017
meiotic nuclear division GO:0007126 4 0.017
regulation of transcription dna templated GO:0006355 213 0.017
odontogenesis of dentin containing tooth GO:0042475 1 0.016
g2 m transition of mitotic cell cycle GO:0000086 4 0.016
regulation of meiotic cell cycle GO:0051445 1 0.016
protein targeting to nucleus GO:0044744 3 0.016
action potential GO:0001508 19 0.016
ion homeostasis GO:0050801 41 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.016
cellular response to biotic stimulus GO:0071216 3 0.016
developmental growth involved in morphogenesis GO:0060560 86 0.016
Zebrafish
gene expression GO:0010467 252 0.016
regulation of response to stimulus GO:0048583 269 0.016
Human Mouse
response to vitamin GO:0033273 3 0.016
regulation of signaling GO:0023051 235 0.016
Human Mouse
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
sensory system development GO:0048880 76 0.015
stem cell development GO:0048864 82 0.015
membrane repolarization GO:0086009 2 0.015
regulation of ion transmembrane transport GO:0034765 18 0.015
regulation of tube size GO:0035150 2 0.015
digestive tract morphogenesis GO:0048546 231 0.015
collagen fibril organization GO:0030199 1 0.015
Zebrafish
spindle assembly involved in mitosis GO:0090307 1 0.015
cranial ganglion development GO:0061550 3 0.015
positive regulation of histone modification GO:0031058 1 0.015
cellular response to retinoic acid GO:0071300 1 0.015
regulation of protein transport GO:0051223 3 0.015
startle response GO:0001964 4 0.014
post embryonic organ development GO:0048569 4 0.014
pectoral fin development GO:0033339 50 0.014
mechanosensory lateral line system development GO:0048881 49 0.014
determination of bilateral symmetry GO:0009855 204 0.014
cellular macromolecule metabolic process GO:0044260 391 0.014
Zebrafish
muscle organ development GO:0007517 101 0.014
regulation of cardiac muscle contraction GO:0055117 2 0.014
lateral line system development GO:0048925 76 0.014
otic vesicle development GO:0071599 42 0.014
endoderm development GO:0007492 49 0.014
positive regulation of blood circulation GO:1903524 2 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
glucocorticoid metabolic process GO:0008211 2 0.014
multicellular organismal homeostasis GO:0048871 29 0.014
regulation of macromolecule metabolic process GO:0060255 317 0.014
cellular ketone metabolic process GO:0042180 11 0.014
regulation of myotube differentiation GO:0010830 2 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
embryonic heart tube development GO:0035050 133 0.013
negative regulation of defense response GO:0031348 2 0.013
cellular protein catabolic process GO:0044257 4 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
neural crest cell migration GO:0001755 42 0.013
tissue regeneration GO:0042246 74 0.013
embryonic eye morphogenesis GO:0048048 30 0.013
Zebrafish
epiboly GO:0090504 41 0.013
protein import into nucleus GO:0006606 3 0.013
actin mediated cell contraction GO:0070252 1 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
eye morphogenesis GO:0048592 144 0.013
Zebrafish
single organism metabolic process GO:0044710 217 0.013
Zebrafish
cellular component biogenesis GO:0044085 178 0.013
gtp catabolic process GO:0006184 2 0.013
regulation of ion transport GO:0043269 22 0.013
cellular response to unfolded protein GO:0034620 2 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
epithelial cell development GO:0002064 42 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
Human Mouse
striated muscle cell development GO:0055002 108 0.013
regulation of protein catabolic process GO:0042176 1 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
Mouse
determination of left right symmetry GO:0007368 179 0.013
cellular component assembly GO:0022607 170 0.013
neuron fate determination GO:0048664 2 0.013
epidermal cell differentiation GO:0009913 36 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
neuroblast proliferation GO:0007405 2 0.012
brain development GO:0007420 293 0.012
calcium ion transmembrane transport GO:0070588 13 0.012
positive regulation of cellular process GO:0048522 201 0.012
nitric oxide metabolic process GO:0046209 2 0.012
regulation of cell activation GO:0050865 1 0.012
protein import GO:0017038 3 0.012
formation of primary germ layer GO:0001704 62 0.012
negative regulation of cellular biosynthetic process GO:0031327 55 0.012
phosphorus metabolic process GO:0006793 109 0.012
macromolecule modification GO:0043412 111 0.012
ion transport GO:0006811 114 0.012
stem cell division GO:0017145 1 0.012
chemotaxis GO:0006935 104 0.012
single organism localization GO:1902578 225 0.012
regulation of developmental process GO:0050793 247 0.012
Mouse
cellular amino acid metabolic process GO:0006520 7 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
multicellular organismal metabolic process GO:0044236 2 0.012
cytoskeleton organization GO:0007010 96 0.012
protein metabolic process GO:0019538 183 0.012
Zebrafish
smooth muscle contraction GO:0006939 2 0.011
myeloid leukocyte mediated immunity GO:0002444 1 0.011
sequestering of metal ion GO:0051238 3 0.011
chemical homeostasis GO:0048878 49 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
Mouse
gland development GO:0048732 143 0.011
antimicrobial humoral response GO:0019730 2 0.011
system process GO:0003008 185 0.011
embryonic skeletal joint morphogenesis GO:0060272 3 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
stem cell proliferation GO:0072089 4 0.011
regulation of growth GO:0040008 42 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
water homeostasis GO:0030104 4 0.011
locomotion GO:0040011 313 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
hormone secretion GO:0046879 2 0.011
small molecule metabolic process GO:0044281 77 0.011
Zebrafish
neuron projection development GO:0031175 180 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
cell migration involved in heart development GO:0060973 22 0.011
metal ion transport GO:0030001 58 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
neuronal action potential GO:0019228 18 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
kidney development GO:0001822 92 0.011
cytokinesis GO:0000910 3 0.011
positive regulation of metabolic process GO:0009893 108 0.011
response to nutrient GO:0007584 3 0.011
positive regulation of gene expression GO:0010628 71 0.010
regulation of programmed cell death GO:0043067 101 0.010
multicellular organismal signaling GO:0035637 22 0.010
carbohydrate homeostasis GO:0033500 1 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
cellular localization GO:0051641 97 0.010
lens fiber cell development GO:0070307 3 0.010
epithelial tube morphogenesis GO:0060562 148 0.010
regulation of axonogenesis GO:0050770 32 0.010
regulation of mrna splicing via spliceosome GO:0048024 3 0.010
cellular response to radiation GO:0071478 4 0.010
response to wounding GO:0009611 116 0.010
regulation of blood circulation GO:1903522 32 0.010
immune system development GO:0002520 191 0.010

aspn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.080
musculoskeletal system disease DOID:17 0 0.038
muscular disease DOID:0080000 0 0.034
muscle tissue disease DOID:66 0 0.029
distal arthrogryposis DOID:0050646 0 0.016
nervous system disease DOID:863 0 0.014
disease of cellular proliferation DOID:14566 0 0.011