Danio rerio

11 known processes

lzic

leucine zipper and CTNNBIP1 domain containing

(Aliases: zgc:92310)

lzic biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.278
neuron projection morphogenesis GO:0048812 161 0.265
cell part morphogenesis GO:0032990 246 0.254
cell projection organization GO:0030030 284 0.217
neuron differentiation GO:0030182 353 0.199
response to external stimulus GO:0009605 264 0.193
cellular component morphogenesis GO:0032989 336 0.171
aging GO:0007568 2 0.169
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.166
larval development GO:0002164 2 0.158
digestive system development GO:0055123 289 0.153
sensory organ development GO:0007423 393 0.142
brain development GO:0007420 293 0.130
neuron projection development GO:0031175 180 0.126
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.124
regulation of macromolecule metabolic process GO:0060255 317 0.123
negative regulation of biological process GO:0048519 304 0.118
gene expression GO:0010467 252 0.115
cellular aromatic compound metabolic process GO:0006725 295 0.111
nucleobase containing compound metabolic process GO:0006139 274 0.110
tube morphogenesis GO:0035239 349 0.103
axonogenesis GO:0007409 152 0.102
nucleobase containing compound biosynthetic process GO:0034654 205 0.101
cellular macromolecule biosynthetic process GO:0034645 224 0.099
cell projection morphogenesis GO:0048858 244 0.098
morphogenesis of an epithelium GO:0002009 333 0.097
cell morphogenesis GO:0000902 289 0.095
adult behavior GO:0030534 2 0.090
heterocycle metabolic process GO:0046483 290 0.088
regulation of multicellular organismal process GO:0051239 277 0.087
cellular nitrogen compound metabolic process GO:0034641 290 0.087
regulation of transcription dna templated GO:0006355 213 0.084
cellular macromolecule metabolic process GO:0044260 391 0.081
head development GO:0060322 303 0.081
female sex differentiation GO:0046660 4 0.080
regulation of metabolic process GO:0019222 359 0.075
aromatic compound biosynthetic process GO:0019438 217 0.075
cell morphogenesis involved in differentiation GO:0000904 195 0.075
generation of neurons GO:0048699 385 0.074
regulation of developmental process GO:0050793 247 0.074
response to stress GO:0006950 263 0.068
macromolecule biosynthetic process GO:0009059 227 0.065
cellular protein catabolic process GO:0044257 4 0.065
heterocycle biosynthetic process GO:0018130 215 0.065
organic substance biosynthetic process GO:1901576 289 0.061
nucleic acid metabolic process GO:0090304 244 0.060
regulation of neurogenesis GO:0050767 87 0.059
rna metabolic process GO:0016070 219 0.059
cellular biosynthetic process GO:0044249 286 0.057
transcription dna templated GO:0006351 181 0.056
regulation of embryonic development GO:0045995 47 0.055
rna biosynthetic process GO:0032774 181 0.055
microtubule organizing center organization GO:0031023 1 0.053
regulation of rna biosynthetic process GO:2001141 213 0.051
axon guidance GO:0007411 86 0.051
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.048
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.047
embryo development ending in birth or egg hatching GO:0009792 271 0.046
axon development GO:0061564 166 0.046
regulation of synaptic plasticity GO:0048167 1 0.046
dorsal ventral pattern formation GO:0009953 125 0.044
inner ear development GO:0048839 126 0.043
embryonic organ development GO:0048568 381 0.042
eye development GO:0001654 277 0.042
regulation of cell death GO:0010941 103 0.041
ubiquitin dependent protein catabolic process GO:0006511 3 0.041
digestive tract morphogenesis GO:0048546 231 0.041
nitrogen compound metabolic process GO:0006807 319 0.041
nucleic acid templated transcription GO:0097659 181 0.040
negative regulation of cellular process GO:0048523 283 0.039
establishment of localization GO:0051234 244 0.039
regulation of biological quality GO:0065008 263 0.039
protein metabolic process GO:0019538 183 0.038
protein modification process GO:0036211 100 0.037
regulation of nitrogen compound metabolic process GO:0051171 251 0.037
regulation of nervous system development GO:0051960 90 0.037
kidney development GO:0001822 92 0.037
transcription from rna polymerase ii promoter GO:0006366 80 0.035
compound eye development GO:0048749 2 0.035
cellular component movement GO:0006928 335 0.035
regulation of cellular metabolic process GO:0031323 320 0.035
regionalization GO:0003002 274 0.034
apoptotic process GO:0006915 116 0.034
positive regulation of cell cycle GO:0045787 3 0.033
neuron development GO:0048666 262 0.032
ear development GO:0043583 127 0.032
regulation of cellular biosynthetic process GO:0031326 245 0.032
developmental maturation GO:0021700 34 0.032
cellular nitrogen compound biosynthetic process GO:0044271 218 0.031
multicellular organism growth GO:0035264 4 0.031
gastrulation GO:0007369 208 0.031
proteasomal protein catabolic process GO:0010498 2 0.031
pancreas development GO:0031016 84 0.031
stem cell differentiation GO:0048863 117 0.031
cellular response to nutrient levels GO:0031669 2 0.030
cell surface receptor signaling pathway GO:0007166 325 0.030
regulation of primary metabolic process GO:0080090 311 0.030
regulation of biosynthetic process GO:0009889 250 0.030
homeostatic process GO:0042592 142 0.029
modification dependent macromolecule catabolic process GO:0043632 3 0.029
guanosine containing compound metabolic process GO:1901068 4 0.029
signal transduction GO:0007165 455 0.029
biosynthetic process GO:0009058 294 0.028
female gonad development GO:0008585 4 0.028
regulation of nucleic acid templated transcription GO:1903506 213 0.028
phagocytosis GO:0006909 3 0.028
regulation of synapse organization GO:0050807 3 0.028
primary neural tube formation GO:0014020 1 0.028
regulation of cell differentiation GO:0045595 142 0.028
regulation of multicellular organismal development GO:2000026 223 0.028
regulation of response to stimulus GO:0048583 269 0.028
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.028
sleep GO:0030431 1 0.027
modification dependent protein catabolic process GO:0019941 3 0.027
developmental growth GO:0048589 166 0.027
monoamine transport GO:0015844 1 0.027
growth GO:0040007 174 0.027
regulation of cell communication GO:0010646 232 0.027
negative regulation of protein transport GO:0051224 3 0.027
cellular protein modification process GO:0006464 100 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.027
locomotion GO:0040011 313 0.027
cognition GO:0050890 1 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.026
organic cyclic compound metabolic process GO:1901360 301 0.026
regulation of protein ubiquitination GO:0031396 3 0.026
positive regulation of cellular component biogenesis GO:0044089 3 0.025
cellular lipid catabolic process GO:0044242 3 0.025
regulation of protein transport GO:0051223 3 0.025
response to chemical GO:0042221 320 0.025
regulation of macromolecule biosynthetic process GO:0010556 225 0.025
cell motility GO:0048870 244 0.025
sensory organ morphogenesis GO:0090596 200 0.025
development of primary female sexual characteristics GO:0046545 4 0.024
cellular response to oxygen levels GO:0071453 1 0.024
membrane fusion GO:0061025 2 0.024
single organism membrane fusion GO:0044801 2 0.024
localization of cell GO:0051674 244 0.024
maintenance of location GO:0051235 4 0.024
centrosome organization GO:0051297 1 0.024
cell fate specification GO:0001708 68 0.024
positive regulation of neuron apoptotic process GO:0043525 1 0.024
urogenital system development GO:0001655 97 0.023
neuron projection guidance GO:0097485 86 0.023
erk1 and erk2 cascade GO:0070371 4 0.023
programmed cell death GO:0012501 119 0.023
taxis GO:0042330 109 0.023
single organism reproductive process GO:0044702 40 0.023
regulation of reproductive process GO:2000241 4 0.023
nuclear transport GO:0051169 4 0.023
angiogenesis GO:0001525 158 0.022
protein dephosphorylation GO:0006470 3 0.022
regulation of erk1 and erk2 cascade GO:0070372 4 0.022
macromolecule modification GO:0043412 111 0.022
regulation of circadian rhythm GO:0042752 4 0.022
death GO:0016265 121 0.022
establishment of protein localization to organelle GO:0072594 4 0.021
establishment of localization in cell GO:0051649 77 0.021
protein modification by small protein conjugation or removal GO:0070647 14 0.021
mitotic cell cycle embryonic GO:0045448 2 0.021
organic cyclic compound biosynthetic process GO:1901362 223 0.020
negative regulation of gene expression GO:0010629 65 0.020
regulation of cell shape GO:0008360 1 0.020
glucose homeostasis GO:0042593 1 0.020
g1 s transition of mitotic cell cycle GO:0000082 1 0.020
circadian sleep wake cycle GO:0042745 2 0.020
single organism transport GO:0044765 206 0.020
regulation of receptor activity GO:0010469 2 0.020
regulation of rna metabolic process GO:0051252 224 0.019
regulation of neuronal synaptic plasticity GO:0048168 1 0.019
transport GO:0006810 220 0.019
lipid homeostasis GO:0055088 3 0.019
phosphorylation GO:0016310 69 0.019
regulation of microtubule cytoskeleton organization GO:0070507 3 0.019
multi organism process GO:0051704 134 0.019
cell migration GO:0016477 237 0.019
regulation of synapse assembly GO:0051963 3 0.019
system process GO:0003008 185 0.018
stem cell maintenance GO:0019827 4 0.018
single organism organelle organization GO:1902589 199 0.018
golgi vesicle transport GO:0048193 3 0.018
otolith development GO:0048840 32 0.018
renal system development GO:0072001 94 0.018
digestive tract development GO:0048565 265 0.018
tube closure GO:0060606 1 0.018
single organism metabolic process GO:0044710 217 0.018
inner ear morphogenesis GO:0042472 63 0.017
phagocytosis engulfment GO:0006911 1 0.017
camera type eye development GO:0043010 222 0.017
wnt signaling pathway GO:0016055 80 0.017
regulation of neuron projection development GO:0010975 40 0.017
membrane invagination GO:0010324 1 0.017
calcium ion transport into cytosol GO:0060402 3 0.017
organonitrogen compound metabolic process GO:1901564 74 0.017
cell projection assembly GO:0030031 64 0.017
cellular response to external stimulus GO:0071496 2 0.016
appendage morphogenesis GO:0035107 56 0.016
blood vessel morphogenesis GO:0048514 216 0.016
negative regulation of biosynthetic process GO:0009890 55 0.016
regulation of cellular component organization GO:0051128 86 0.016
pronephros development GO:0048793 69 0.016
gtp catabolic process GO:0006184 2 0.016
cellular response to decreased oxygen levels GO:0036294 1 0.016
membrane organization GO:0061024 21 0.015
negative regulation of cellular biosynthetic process GO:0031327 55 0.015
ear morphogenesis GO:0042471 64 0.015
regulation of cell cycle GO:0051726 52 0.015
negative regulation of transcription dna templated GO:0045892 45 0.015
regulation of anatomical structure morphogenesis GO:0022603 130 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
regulation of signaling GO:0023051 235 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.015
germ line stem cell maintenance GO:0030718 2 0.015
heart development GO:0007507 313 0.015
myeloid cell differentiation GO:0030099 86 0.015
small molecule catabolic process GO:0044282 3 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
regulation of jak stat cascade GO:0046425 3 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.014
cell substrate adhesion GO:0031589 4 0.014
anion homeostasis GO:0055081 9 0.014
negative regulation of developmental process GO:0051093 65 0.014
cell death GO:0008219 121 0.014
response to carbohydrate GO:0009743 3 0.014
response to hexose GO:0009746 3 0.014
sympathetic ganglion development GO:0061549 2 0.014
negative regulation of neuron projection regeneration GO:0070571 4 0.013
neuromuscular synaptic transmission GO:0007274 2 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
neuron migration GO:0001764 22 0.013
photoreceptor cell differentiation GO:0046530 55 0.013
centrosome duplication GO:0051298 1 0.013
immune system process GO:0002376 241 0.013
neuron neuron synaptic transmission GO:0007270 1 0.013
regulation of transporter activity GO:0032409 2 0.013
organelle organization GO:0006996 227 0.013
somatic muscle development GO:0007525 4 0.013
organelle fusion GO:0048284 3 0.012
chordate embryonic development GO:0043009 271 0.012
lipid storage GO:0019915 1 0.012
protein secretion GO:0009306 1 0.012
chemotaxis GO:0006935 104 0.012
meiotic nuclear division GO:0007126 4 0.012
convergent extension GO:0060026 118 0.012
negative regulation of metabolic process GO:0009892 86 0.012
response to wounding GO:0009611 116 0.012
retina layer formation GO:0010842 24 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
regulation of protein catabolic process GO:0042176 1 0.012
positive regulation of transport GO:0051050 2 0.012
regulation of gene expression GO:0010468 265 0.012
phosphorus metabolic process GO:0006793 109 0.012
centrosome cycle GO:0007098 1 0.012
eye morphogenesis GO:0048592 144 0.012
regulation of dendrite development GO:0050773 3 0.012
cellular amine metabolic process GO:0044106 2 0.011
positive regulation of neuron death GO:1901216 1 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
carbohydrate homeostasis GO:0033500 1 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
regulation of cell projection organization GO:0031344 44 0.011
wound healing GO:0042060 90 0.011
cellular component assembly GO:0022607 170 0.011
skin development GO:0043588 54 0.011
circadian sleep wake cycle sleep GO:0050802 1 0.011
peripheral nervous system development GO:0007422 55 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
positive regulation of notch signaling pathway GO:0045747 3 0.011
regulation of neuron differentiation GO:0045664 56 0.011
peptide transport GO:0015833 1 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
regulation of programmed cell death GO:0043067 101 0.011
embryonic skeletal system morphogenesis GO:0048704 93 0.011
response to endogenous stimulus GO:0009719 83 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
nucleocytoplasmic transport GO:0006913 4 0.011
autophagy GO:0006914 4 0.011
embryonic skeletal system development GO:0048706 97 0.011
regulation of cytokine production GO:0001817 3 0.011
response to hydrogen peroxide GO:0042542 3 0.011
regulation of signal transduction GO:0009966 225 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
sympathetic nervous system development GO:0048485 3 0.011
cellular protein metabolic process GO:0044267 129 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
hatching GO:0035188 4 0.010
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.010
regulation of stem cell proliferation GO:0072091 2 0.010
auditory receptor cell fate commitment GO:0009912 4 0.010
regulation of nucleotide catabolic process GO:0030811 2 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010
release of sequestered calcium ion into cytosol GO:0051209 3 0.010
sensory perception of chemical stimulus GO:0007606 3 0.010
positive regulation of transcription dna templated GO:0045893 57 0.010
positive regulation of secretion GO:0051047 1 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.010
synaptic vesicle localization GO:0097479 1 0.010
mediolateral intercalation GO:0060031 3 0.010
defense response GO:0006952 47 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.010
nuclear import GO:0051170 3 0.010

lzic disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.067
cancer DOID:162 0 0.021
organ system cancer DOID:0050686 0 0.016
disease of metabolism DOID:0014667 0 0.015
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.010
cardiovascular system disease DOID:1287 0 0.010