Danio rerio

13 known processes

lsr

lipolysis stimulated lipoprotein receptor

(Aliases: zgc:114089,MGC114089,Lisch7,lsrl)

lsr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
morphogenesis of an epithelium GO:0002009 333 0.483
sensory organ development GO:0007423 393 0.270
chordate embryonic development GO:0043009 271 0.246
cellular component biogenesis GO:0044085 178 0.229
immune system development GO:0002520 191 0.190
cilium organization GO:0044782 71 0.185
epiboly GO:0090504 41 0.178
digestive tract development GO:0048565 265 0.148
cell motility GO:0048870 244 0.140
apical junction assembly GO:0043297 1 0.134
nucleocytoplasmic transport GO:0006913 4 0.131
single organism localization GO:1902578 225 0.125
nuclear transport GO:0051169 4 0.115
cell migration GO:0016477 237 0.112
regulation of primary metabolic process GO:0080090 311 0.110
cellular macromolecule metabolic process GO:0044260 391 0.105
actin filament based movement GO:0030048 1 0.104
regulation of sodium ion transport GO:0002028 2 0.098
gene expression GO:0010467 252 0.098
biosynthetic process GO:0009058 294 0.097
myoblast fusion GO:0007520 10 0.097
epidermis development GO:0008544 48 0.095
nucleic acid metabolic process GO:0090304 244 0.095
macromolecule biosynthetic process GO:0009059 227 0.093
homeostatic process GO:0042592 142 0.090
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.090
aging GO:0007568 2 0.090
protein import into nucleus GO:0006606 3 0.089
negative regulation of stem cell differentiation GO:2000737 2 0.089
cell chemotaxis GO:0060326 17 0.088
response to amino acid GO:0043200 2 0.083
regulation of multicellular organism growth GO:0040014 4 0.082
regulation of macromolecule metabolic process GO:0060255 317 0.081
cellular component assembly GO:0022607 170 0.080
s adenosylmethionine metabolic process GO:0046500 1 0.072
immune system process GO:0002376 241 0.072
regulation of cellular protein metabolic process GO:0032268 52 0.071
regulation of rna metabolic process GO:0051252 224 0.070
protein k48 linked ubiquitination GO:0070936 1 0.069
establishment of epithelial cell polarity GO:0090162 2 0.069
defense response to other organism GO:0098542 33 0.069
negative regulation of biological process GO:0048519 304 0.069
cellular localization GO:0051641 97 0.068
epithelial cell differentiation GO:0030855 116 0.068
organelle assembly GO:0070925 110 0.068
digestive system development GO:0055123 289 0.067
protein metabolic process GO:0019538 183 0.066
cellular component morphogenesis GO:0032989 336 0.066
protein localization to nucleus GO:0034504 3 0.066
growth GO:0040007 174 0.062
organic substance biosynthetic process GO:1901576 289 0.062
digestive tract morphogenesis GO:0048546 231 0.061
regulation of intracellular protein transport GO:0033157 3 0.059
embryo development ending in birth or egg hatching GO:0009792 271 0.058
regulation of rna biosynthetic process GO:2001141 213 0.057
embryonic organ morphogenesis GO:0048562 274 0.057
cellular component assembly involved in morphogenesis GO:0010927 107 0.057
negative regulation of response to stimulus GO:0048585 104 0.057
microtubule bundle formation GO:0001578 9 0.055
positive regulation of macromolecule metabolic process GO:0010604 93 0.055
centrosome cycle GO:0007098 1 0.054
negative regulation of neural precursor cell proliferation GO:2000178 1 0.053
regulation of nitrogen compound metabolic process GO:0051171 251 0.053
tube morphogenesis GO:0035239 349 0.052
single organism nuclear import GO:1902593 3 0.052
regulation of protein localization to nucleus GO:1900180 2 0.052
developmental growth GO:0048589 166 0.052
regulation of dna templated transcription in response to stress GO:0043620 0 0.052
regulation of nucleic acid templated transcription GO:1903506 213 0.052
cell projection morphogenesis GO:0048858 244 0.051
pigmentation GO:0043473 85 0.051
hematopoietic or lymphoid organ development GO:0048534 191 0.051
skin development GO:0043588 54 0.050
kidney development GO:0001822 92 0.050
regulation of biosynthetic process GO:0009889 250 0.050
neuroblast differentiation GO:0014016 1 0.049
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.049
establishment of protein localization to organelle GO:0072594 4 0.048
protein modification process GO:0036211 100 0.048
response to external biotic stimulus GO:0043207 97 0.048
cellular protein metabolic process GO:0044267 129 0.048
epidermis morphogenesis GO:0048730 4 0.048
autophagy GO:0006914 4 0.048
cellular modified amino acid metabolic process GO:0006575 3 0.048
macromolecule modification GO:0043412 111 0.047
macrophage chemotaxis GO:0048246 3 0.046
chemical homeostasis GO:0048878 49 0.045
positive regulation of transport GO:0051050 2 0.044
regulation of macromolecule biosynthetic process GO:0010556 225 0.043
negative regulation of cellular process GO:0048523 283 0.043
nuclear import GO:0051170 3 0.042
multicellular organism growth GO:0035264 4 0.042
desmosome organization GO:0002934 3 0.042
neuron differentiation GO:0030182 353 0.041
protein import GO:0017038 3 0.041
cellular amino acid metabolic process GO:0006520 7 0.040
inner ear development GO:0048839 126 0.040
cell projection organization GO:0030030 284 0.040
cellular response to extracellular stimulus GO:0031668 2 0.040
regulation of multicellular organismal development GO:2000026 223 0.039
ear development GO:0043583 127 0.039
cell part morphogenesis GO:0032990 246 0.039
cellular component movement GO:0006928 335 0.039
cilium assembly GO:0042384 58 0.038
heterocycle biosynthetic process GO:0018130 215 0.038
cellular biosynthetic process GO:0044249 286 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.038
determination of bilateral symmetry GO:0009855 204 0.038
ectoderm development GO:0007398 9 0.038
rna metabolic process GO:0016070 219 0.037
regulation of cellular metabolic process GO:0031323 320 0.037
epidermal cell differentiation GO:0009913 36 0.036
epithelial cell development GO:0002064 42 0.036
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.036
regulation of cellular biosynthetic process GO:0031326 245 0.036
cell junction organization GO:0034330 11 0.035
cardiac cell fate commitment GO:0060911 1 0.035
regulation of stem cell proliferation GO:0072091 2 0.035
monovalent inorganic cation transport GO:0015672 42 0.035
cell growth GO:0016049 57 0.034
regulation of metabolic process GO:0019222 359 0.034
retina morphogenesis in camera type eye GO:0060042 79 0.034
organic cyclic compound biosynthetic process GO:1901362 223 0.034
response to external stimulus GO:0009605 264 0.034
taxis GO:0042330 109 0.033
lateral line system development GO:0048925 76 0.033
regulation of metal ion transport GO:0010959 4 0.033
morphogenesis of an epithelial sheet GO:0002011 49 0.033
regulation of transcription dna templated GO:0006355 213 0.032
establishment or maintenance of apical basal cell polarity GO:0035088 12 0.031
cellular macromolecule biosynthetic process GO:0034645 224 0.031
skeletal system development GO:0001501 181 0.031
intestinal epithelial cell differentiation GO:0060575 3 0.031
metal ion transport GO:0030001 58 0.030
cilium morphogenesis GO:0060271 85 0.030
negative regulation of immune response GO:0050777 2 0.030
transport GO:0006810 220 0.030
heart process GO:0003015 71 0.029
regulation of protein targeting GO:1903533 2 0.029
negative regulation of signal transduction GO:0009968 94 0.029
macroautophagy GO:0016236 1 0.029
establishment of endothelial barrier GO:0061028 3 0.029
signal transduction GO:0007165 455 0.029
hemopoiesis GO:0030097 183 0.029
biological adhesion GO:0022610 40 0.028
cell morphogenesis GO:0000902 289 0.028
chemotaxis GO:0006935 104 0.028
system process GO:0003008 185 0.028
heart development GO:0007507 313 0.027
nucleic acid templated transcription GO:0097659 181 0.027
regulation of biological quality GO:0065008 263 0.027
cellular protein localization GO:0034613 20 0.027
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.026
convergent extension GO:0060026 118 0.026
endoderm development GO:0007492 49 0.026
camera type eye development GO:0043010 222 0.026
protein localization GO:0008104 40 0.025
gastrulation with mouth forming second GO:0001702 44 0.025
neutrophil migration GO:1990266 10 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
epithelial cell morphogenesis GO:0003382 2 0.025
response to stress GO:0006950 263 0.025
rna biosynthetic process GO:0032774 181 0.025
cellular protein catabolic process GO:0044257 4 0.025
regulation of blood pressure GO:0008217 1 0.025
organonitrogen compound metabolic process GO:1901564 74 0.025
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.025
cellular carbohydrate metabolic process GO:0044262 4 0.024
neuroblast proliferation GO:0007405 2 0.024
dorsal fin morphogenesis GO:0035142 1 0.024
regulation of eye photoreceptor cell development GO:0042478 2 0.024
single organism metabolic process GO:0044710 217 0.024
sensory organ morphogenesis GO:0090596 200 0.024
transcription dna templated GO:0006351 181 0.024
regulation of neural precursor cell proliferation GO:2000177 3 0.024
regulation of cell death GO:0010941 103 0.024
cellular response to external stimulus GO:0071496 2 0.024
transcription from rna polymerase ii promoter GO:0006366 80 0.023
organic substance transport GO:0071702 58 0.023
regulation of nervous system development GO:0051960 90 0.023
protein targeting to membrane GO:0006612 1 0.023
response to abiotic stimulus GO:0009628 122 0.023
single organism transport GO:0044765 206 0.023
generation of neurons GO:0048699 385 0.023
vasculature development GO:0001944 278 0.023
regulation of protein transport GO:0051223 3 0.023
response to chemical GO:0042221 320 0.023
protein targeting to nucleus GO:0044744 3 0.023
response to other organism GO:0051707 97 0.022
photoreceptor cell fate specification GO:0043704 1 0.022
neuroblast fate commitment GO:0014017 1 0.022
negative regulation of protein kinase activity GO:0006469 4 0.022
brain development GO:0007420 293 0.022
regulation of nucleocytoplasmic transport GO:0046822 2 0.022
establishment or maintenance of cell polarity GO:0007163 29 0.022
urogenital system development GO:0001655 97 0.021
establishment of localization GO:0051234 244 0.021
cellular protein modification process GO:0006464 100 0.021
renal system development GO:0072001 94 0.021
mesenchyme development GO:0060485 127 0.021
response to bacterium GO:0009617 58 0.021
cell cell junction organization GO:0045216 10 0.021
protein complex disassembly GO:0043241 1 0.021
regulation of anatomical structure morphogenesis GO:0022603 130 0.020
sodium ion transport GO:0006814 24 0.020
hydrogen peroxide metabolic process GO:0042743 2 0.020
multicellular organismal signaling GO:0035637 22 0.020
organic cyclic compound metabolic process GO:1901360 301 0.020
cellular nitrogen compound biosynthetic process GO:0044271 218 0.020
phosphorylation GO:0016310 69 0.020
stem cell proliferation GO:0072089 4 0.020
central nervous system development GO:0007417 387 0.020
phagocytosis GO:0006909 3 0.020
angiogenesis GO:0001525 158 0.020
eye development GO:0001654 277 0.019
negative regulation of signaling GO:0023057 96 0.019
polarized epithelial cell differentiation GO:0030859 4 0.019
neurological system process GO:0050877 62 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
regulation of innate immune response GO:0045088 11 0.019
regulation of epithelial to mesenchymal transition GO:0010717 3 0.019
neuron development GO:0048666 262 0.019
regulation of dna replication GO:0006275 3 0.019
nitrogen compound metabolic process GO:0006807 319 0.019
intracellular signal transduction GO:0035556 85 0.019
regulation of localization GO:0032879 104 0.019
eye morphogenesis GO:0048592 144 0.018
microtubule based process GO:0007017 60 0.018
water homeostasis GO:0030104 4 0.018
cation homeostasis GO:0055080 33 0.018
establishment of organelle localization GO:0051656 45 0.018
gland development GO:0048732 143 0.018
Mouse
regulation of multicellular organismal process GO:0051239 277 0.018
lateral line development GO:0048882 66 0.018
epithelial tube morphogenesis GO:0060562 148 0.018
cellular response to starvation GO:0009267 1 0.018
nucleobase containing compound biosynthetic process GO:0034654 205 0.018
cell junction assembly GO:0034329 7 0.017
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.017
skeletal system morphogenesis GO:0048705 102 0.017
striated muscle cell differentiation GO:0051146 129 0.017
gastrulation GO:0007369 208 0.017
cell cell adhesion involved in mesendodermal cell migration GO:0003370 1 0.017
lymph vessel morphogenesis GO:0036303 25 0.017
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.017
response to radiation GO:0009314 51 0.017
cardiac conduction GO:0061337 3 0.017
nucleobase containing compound metabolic process GO:0006139 274 0.017
organelle localization GO:0051640 49 0.017
desmosome assembly GO:0002159 2 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.017
cellular response to chemical stimulus GO:0070887 157 0.016
multi organism process GO:0051704 134 0.016
localization of cell GO:0051674 244 0.016
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
epithelial cilium movement involved in determination of left right asymmetry GO:0060287 8 0.016
cellular aromatic compound metabolic process GO:0006725 295 0.016
female sex differentiation GO:0046660 4 0.016
embryonic skeletal system development GO:0048706 97 0.016
cellular response to fatty acid GO:0071398 3 0.016
cation transport GO:0006812 81 0.016
heart looping GO:0001947 94 0.016
negative regulation of cellular metabolic process GO:0031324 77 0.016
negative chemotaxis GO:0050919 1 0.016
actin polymerization or depolymerization GO:0008154 2 0.016
single organism cellular localization GO:1902580 46 0.016
cellular response to nutrient levels GO:0031669 2 0.016
regulation of photoreceptor cell differentiation GO:0046532 2 0.016
positive regulation of map kinase activity GO:0043406 3 0.016
cell substrate adhesion GO:0031589 4 0.015
dna templated transcription elongation GO:0006354 3 0.015
mechanoreceptor differentiation GO:0042490 37 0.015
cell death GO:0008219 121 0.015
positive regulation of carbohydrate metabolic process GO:0045913 1 0.015
negative regulation of cell communication GO:0010648 96 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
sensory perception GO:0007600 39 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
mesenchymal cell differentiation GO:0048762 87 0.014
cellular component maintenance GO:0043954 3 0.014
developmental growth involved in morphogenesis GO:0060560 86 0.014
inner ear receptor stereocilium organization GO:0060122 8 0.014
axonal defasciculation GO:0007414 2 0.014
response to topologically incorrect protein GO:0035966 2 0.014
vesicle localization GO:0051648 27 0.014
cytokinesis GO:0000910 3 0.014
embryonic skeletal system morphogenesis GO:0048704 93 0.014
negative regulation of innate immune response GO:0045824 2 0.014
neuromast development GO:0048884 46 0.014
membrane fusion GO:0061025 2 0.014
protein polymerization GO:0051258 4 0.014
mesenchymal cell development GO:0014031 78 0.014
pigment cell differentiation GO:0050931 38 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
stem cell division GO:0017145 1 0.014
stem cell maintenance GO:0019827 4 0.014
lateral inhibition GO:0046331 1 0.014
cellular response to stress GO:0033554 62 0.013
inner ear receptor cell development GO:0060119 20 0.013
embryonic cranial skeleton morphogenesis GO:0048701 90 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
syncytium formation GO:0006949 12 0.013
determination of left right symmetry GO:0007368 179 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
meiotic cell cycle process GO:1903046 3 0.013
golgi vesicle transport GO:0048193 3 0.013
blood vessel development GO:0001568 246 0.013
sensory system development GO:0048880 76 0.013
ion transport GO:0006811 114 0.013
neuronal action potential GO:0019228 18 0.013
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 11 0.013
negative regulation of multicellular organismal process GO:0051241 69 0.013
regulation of protein complex assembly GO:0043254 3 0.013
regulation of phosphate metabolic process GO:0019220 43 0.013
negative regulation of programmed cell death GO:0043069 58 0.013
indole containing compound metabolic process GO:0042430 2 0.013
regulation of jun kinase activity GO:0043506 3 0.013
regulation of response to extracellular stimulus GO:0032104 1 0.013
sulfur compound transport GO:0072348 3 0.013
actin mediated cell contraction GO:0070252 1 0.013
protein polyubiquitination GO:0000209 4 0.012
hepaticobiliary system development GO:0061008 98 0.012
Mouse
ameboidal type cell migration GO:0001667 143 0.012
organic acid metabolic process GO:0006082 31 0.012
response to drug GO:0042493 3 0.012
ion homeostasis GO:0050801 41 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
developmental maturation GO:0021700 34 0.012
negative regulation of developmental process GO:0051093 65 0.012
endoplasmic reticulum unfolded protein response GO:0030968 2 0.012
protein phosphorylation GO:0006468 47 0.012
blood vessel morphogenesis GO:0048514 216 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
regulation of transport GO:0051049 45 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
regulation of signal transduction GO:0009966 225 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
leukocyte chemotaxis GO:0030595 12 0.012
single organism membrane organization GO:0044802 20 0.012
cell adhesion GO:0007155 40 0.012
connective tissue development GO:0061448 99 0.011
adherens junction maintenance GO:0034334 2 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
regulation of gene expression GO:0010468 265 0.011
regulation of heart contraction GO:0008016 32 0.011
sulfur compound metabolic process GO:0006790 13 0.011
death GO:0016265 121 0.011
regulation of neurogenesis GO:0050767 87 0.011
defense response to bacterium GO:0042742 22 0.011
myelin assembly GO:0032288 1 0.011
protein localization to plasma membrane GO:0072659 1 0.011
alpha amino acid metabolic process GO:1901605 3 0.011
cellular response to unfolded protein GO:0034620 2 0.011
establishment of monopolar cell polarity GO:0061162 2 0.011
negative regulation of dna replication GO:0008156 2 0.011
single organism membrane fusion GO:0044801 2 0.011
regulation of epidermis development GO:0045682 2 0.011
regulation of protein catabolic process GO:0042176 1 0.011
regulation of protein metabolic process GO:0051246 56 0.011
anatomical structure arrangement GO:0048532 2 0.011
muscle cell differentiation GO:0042692 139 0.011
very long chain fatty acid biosynthetic process GO:0042761 4 0.011
positive regulation of biological process GO:0048518 253 0.011
regulation of vasculature development GO:1901342 33 0.011
hormone biosynthetic process GO:0042446 3 0.011
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.011
neuron projection development GO:0031175 180 0.011
regulation of programmed cell death GO:0043067 101 0.011
embryonic heart tube development GO:0035050 133 0.010
regulation of cell development GO:0060284 100 0.010
cellular transition metal ion homeostasis GO:0046916 3 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
photoreceptor cell differentiation GO:0046530 55 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010
regulation of cellular component size GO:0032535 30 0.010
regulation of organ growth GO:0046620 3 0.010
centrosome organization GO:0051297 1 0.010
cell cell junction assembly GO:0007043 5 0.010
endosome organization GO:0007032 2 0.010
cell cell adhesion involved in gastrulation GO:0070586 4 0.010

lsr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
myopathy DOID:423 0 0.018
muscular disease DOID:0080000 0 0.018
heart disease DOID:114 0 0.018
cardiomyopathy DOID:0050700 0 0.018
cardiovascular system disease DOID:1287 0 0.018
musculoskeletal system disease DOID:17 0 0.018
muscle tissue disease DOID:66 0 0.018
breast cancer DOID:1612 0 0.012
thoracic cancer DOID:5093 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012
gastrointestinal system cancer DOID:3119 0 0.011