Danio rerio

0 known processes

ela2l

elastase 2 like

(Aliases: wu:fi40a05,MGC111871,ctrc,zgc:63744,elastaseB,zgc:111871,fi40a05)

ela2l biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell surface receptor signaling pathway GO:0007166 325 0.341
lipid catabolic process GO:0016042 4 0.311
cellular macromolecule biosynthetic process GO:0034645 224 0.222
cellular macromolecule metabolic process GO:0044260 391 0.194
signal transduction GO:0007165 455 0.155
steroid metabolic process GO:0008202 7 0.151
organic substance biosynthetic process GO:1901576 289 0.150
zymogen activation GO:0031638 3 0.143
regulation of rna biosynthetic process GO:2001141 213 0.135
aging GO:0007568 2 0.125
small molecule metabolic process GO:0044281 77 0.124
macromolecule biosynthetic process GO:0009059 227 0.120
endothelial cell differentiation GO:0045446 20 0.118
response to nutrient GO:0007584 3 0.112
regulation of macromolecule biosynthetic process GO:0010556 225 0.112
blood vessel morphogenesis GO:0048514 216 0.112
response to amine GO:0014075 1 0.109
multi organism process GO:0051704 134 0.109
proteolysis GO:0006508 38 0.102
single organism metabolic process GO:0044710 217 0.101
heart development GO:0007507 313 0.096
organic cyclic compound metabolic process GO:1901360 301 0.096
cellular biosynthetic process GO:0044249 286 0.094
biosynthetic process GO:0009058 294 0.094
response to alkaloid GO:0043279 2 0.092
protein metabolic process GO:0019538 183 0.092
multicellular organism growth GO:0035264 4 0.089
nucleocytoplasmic transport GO:0006913 4 0.088
lipid metabolic process GO:0006629 52 0.083
cellular response to methanol GO:0071405 4 0.074
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.073
regulation of transcription dna templated GO:0006355 213 0.072
epithelial cell development GO:0002064 42 0.071
regulation of nucleocytoplasmic transport GO:0046822 2 0.071
positive regulation of cellular process GO:0048522 201 0.068
response to monosaccharide GO:0034284 3 0.067
regulation of biosynthetic process GO:0009889 250 0.066
regulation of rna metabolic process GO:0051252 224 0.066
cellular hormone metabolic process GO:0034754 19 0.065
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.065
meiotic nuclear division GO:0007126 4 0.063
cellular nitrogen compound biosynthetic process GO:0044271 218 0.062
terpenoid metabolic process GO:0006721 15 0.062
regulation of cell activation GO:0050865 1 0.061
regulation of primary metabolic process GO:0080090 311 0.056
regulation of biological quality GO:0065008 263 0.056
response to drug GO:0042493 3 0.054
nucleic acid metabolic process GO:0090304 244 0.053
photoperiodism GO:0009648 11 0.053
negative regulation of cellular process GO:0048523 283 0.052
synaptic target recognition GO:0008039 1 0.052
negative regulation of biological process GO:0048519 304 0.051
generation of neurons GO:0048699 385 0.050
regulation of cellular biosynthetic process GO:0031326 245 0.049
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.049
negative regulation of macromolecule metabolic process GO:0010605 76 0.046
response to vitamin b3 GO:0033552 2 0.046
dorsal ventral pattern formation GO:0009953 125 0.045
regulation of macromolecule metabolic process GO:0060255 317 0.045
regulation of multicellular organismal development GO:2000026 223 0.045
cellular component assembly involved in morphogenesis GO:0010927 107 0.045
meiotic chromosome segregation GO:0045132 3 0.045
light induced release of internally sequestered calcium ion GO:0008377 1 0.045
response to carbohydrate GO:0009743 3 0.044
spermatid differentiation GO:0048515 2 0.044
response to nicotine GO:0035094 2 0.044
nuclear import GO:0051170 3 0.043
cellular protein catabolic process GO:0044257 4 0.042
death GO:0016265 121 0.042
positive regulation of transport GO:0051050 2 0.042
regulation of sequestering of calcium ion GO:0051282 4 0.041
regulation of metabolic process GO:0019222 359 0.041
regulation of protein import into nucleus GO:0042306 2 0.041
nuclear transport GO:0051169 4 0.041
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.040
ameboidal type cell migration GO:0001667 143 0.040
protein targeting to nucleus GO:0044744 3 0.039
regulation of signal transduction GO:0009966 225 0.039
single organism localization GO:1902578 225 0.038
i kappab kinase nf kappab signaling GO:0007249 4 0.038
nitrogen compound metabolic process GO:0006807 319 0.038
diterpenoid metabolic process GO:0016101 15 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.037
glucose homeostasis GO:0042593 1 0.037
cellular aromatic compound metabolic process GO:0006725 295 0.037
single organism nuclear import GO:1902593 3 0.037
heterocycle biosynthetic process GO:0018130 215 0.035
cellular nitrogen compound metabolic process GO:0034641 290 0.035
positive regulation of translation GO:0045727 1 0.035
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.035
regulation of cellular metabolic process GO:0031323 320 0.035
digestive system development GO:0055123 289 0.034
response to amphetamine GO:0001975 1 0.034
aromatic compound biosynthetic process GO:0019438 217 0.034
cell morphogenesis GO:0000902 289 0.033
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.033
maintenance of location GO:0051235 4 0.032
blood vessel development GO:0001568 246 0.032
regulation of multicellular organism growth GO:0040014 4 0.032
regulation of developmental process GO:0050793 247 0.032
foregut morphogenesis GO:0007440 4 0.032
response to external stimulus GO:0009605 264 0.031
establishment of localization GO:0051234 244 0.031
lipid biosynthetic process GO:0008610 22 0.031
rna biosynthetic process GO:0032774 181 0.030
establishment of protein localization to organelle GO:0072594 4 0.030
modification dependent macromolecule catabolic process GO:0043632 3 0.030
cellular carbohydrate metabolic process GO:0044262 4 0.030
positive regulation of cellular component biogenesis GO:0044089 3 0.030
heterocycle metabolic process GO:0046483 290 0.029
organic cyclic compound biosynthetic process GO:1901362 223 0.029
regulation of cell communication GO:0010646 232 0.029
nucleic acid templated transcription GO:0097659 181 0.029
extrinsic apoptotic signaling pathway GO:0097191 3 0.029
catabolic process GO:0009056 32 0.028
cellular ketone metabolic process GO:0042180 11 0.028
immune system process GO:0002376 241 0.028
type b pancreatic cell development GO:0003323 4 0.028
regulation of type b pancreatic cell development GO:2000074 1 0.028
defense response GO:0006952 47 0.028
organism emergence from protective structure GO:0071684 4 0.027
transcription from rna polymerase ii promoter GO:0006366 80 0.027
protein localization to nucleus GO:0034504 3 0.027
cellular response to chemical stimulus GO:0070887 157 0.027
larval development GO:0002164 2 0.027
cellular response to stress GO:0033554 62 0.027
response to chemical GO:0042221 320 0.027
positive regulation of cell adhesion GO:0045785 1 0.027
apoptotic process GO:0006915 116 0.027
phagocytosis GO:0006909 3 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
nucleobase containing compound biosynthetic process GO:0034654 205 0.026
amine metabolic process GO:0009308 2 0.026
regulation of nitrogen compound metabolic process GO:0051171 251 0.026
neuron recognition GO:0008038 18 0.026
heart morphogenesis GO:0003007 156 0.026
hematopoietic or lymphoid organ development GO:0048534 191 0.026
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.026
positive regulation of map kinase activity GO:0043406 3 0.025
entrainment of circadian clock GO:0009649 2 0.025
specification of symmetry GO:0009799 204 0.025
response to transition metal nanoparticle GO:1990267 28 0.025
epithelial cell differentiation GO:0030855 116 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.025
positive regulation of cell activation GO:0050867 1 0.025
response to inorganic substance GO:0010035 38 0.025
regulation of multicellular organismal process GO:0051239 277 0.025
regulation of cytokine production GO:0001817 3 0.024
retinoid metabolic process GO:0001523 15 0.024
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.024
intracellular signal transduction GO:0035556 85 0.024
cellular response to xenobiotic stimulus GO:0071466 35 0.024
response to ketone GO:1901654 1 0.024
glucocorticoid metabolic process GO:0008211 2 0.024
negative regulation of metabolic process GO:0009892 86 0.024
cellular response to external stimulus GO:0071496 2 0.023
entrainment of circadian clock by photoperiod GO:0043153 1 0.023
transcription dna templated GO:0006351 181 0.023
digestive tract development GO:0048565 265 0.023
system process GO:0003008 185 0.023
organelle organization GO:0006996 227 0.023
regulation of nucleoside metabolic process GO:0009118 2 0.022
absorption of visible light GO:0016038 2 0.022
cellular lipid metabolic process GO:0044255 36 0.022
regulation of protein localization to nucleus GO:1900180 2 0.022
androgen biosynthetic process GO:0006702 1 0.022
regulation of endocrine process GO:0044060 2 0.022
cellular response to organic substance GO:0071310 105 0.022
epithelium migration GO:0090132 25 0.022
embryonic hemopoiesis GO:0035162 53 0.022
polyol metabolic process GO:0019751 1 0.022
phototransduction GO:0007602 2 0.022
growth GO:0040007 174 0.021
proteasomal protein catabolic process GO:0010498 2 0.021
positive regulation of leukocyte differentiation GO:1902107 1 0.021
localization of cell GO:0051674 244 0.021
response to uv GO:0009411 3 0.021
protein import GO:0017038 3 0.021
bmp signaling pathway GO:0030509 52 0.021
tube morphogenesis GO:0035239 349 0.021
neuron differentiation GO:0030182 353 0.021
b cell differentiation GO:0030183 1 0.021
positive regulation of secretion GO:0051047 1 0.021
reproductive process GO:0022414 40 0.021
protein import into nucleus GO:0006606 3 0.021
determination of bilateral symmetry GO:0009855 204 0.021
regulation of nucleic acid templated transcription GO:1903506 213 0.020
centrosome organization GO:0051297 1 0.020
regulation of inflammatory response GO:0050727 2 0.020
regulation of protein catabolic process GO:0042176 1 0.020
microtubule based process GO:0007017 60 0.020
embryonic organ development GO:0048568 381 0.020
determination of ventral identity GO:0048264 21 0.020
cellular response to starvation GO:0009267 1 0.020
sequestering of metal ion GO:0051238 3 0.020
response to hexose GO:0009746 3 0.020
regulation of proteolysis GO:0030162 24 0.020
regionalization GO:0003002 274 0.020
positive regulation of biological process GO:0048518 253 0.020
positive regulation of protein polymerization GO:0032273 2 0.019
fertilization GO:0009566 3 0.019
modification dependent protein catabolic process GO:0019941 3 0.019
cell cycle GO:0007049 93 0.019
ubiquitin dependent protein catabolic process GO:0006511 3 0.019
gene expression GO:0010467 252 0.019
cell projection organization GO:0030030 284 0.019
regulation of localization GO:0032879 104 0.019
protein secretion GO:0009306 1 0.019
endothelial cell migration GO:0043542 19 0.019
cellular component movement GO:0006928 335 0.019
hatching GO:0035188 4 0.019
regulation of protein binding GO:0043393 3 0.018
phosphate containing compound metabolic process GO:0006796 108 0.018
hemopoiesis GO:0030097 183 0.018
homeostatic process GO:0042592 142 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
cellular lipid catabolic process GO:0044242 3 0.018
negative regulation of cellular metabolic process GO:0031324 77 0.018
digestive tract morphogenesis GO:0048546 231 0.018
response to abiotic stimulus GO:0009628 122 0.018
muscle cell development GO:0055001 115 0.018
regulation of lipid catabolic process GO:0050994 2 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
tissue migration GO:0090130 37 0.018
carbohydrate derivative biosynthetic process GO:1901137 43 0.018
enzyme linked receptor protein signaling pathway GO:0007167 106 0.017
cellular response to estrogen stimulus GO:0071391 24 0.017
developmental process involved in reproduction GO:0003006 27 0.017
neurotransmitter secretion GO:0007269 2 0.017
cellular response to lipid GO:0071396 39 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
regulation of signaling GO:0023051 235 0.017
biological adhesion GO:0022610 40 0.017
negative regulation of nucleic acid templated transcription GO:1903507 45 0.017
response to organic cyclic compound GO:0014070 51 0.017
response to mercury ion GO:0046689 1 0.017
single organism biosynthetic process GO:0044711 71 0.017
vasculature development GO:0001944 278 0.017
endothelium development GO:0003158 25 0.017
intracellular estrogen receptor signaling pathway GO:0030520 3 0.017
single organism transport GO:0044765 206 0.017
positive regulation of catabolic process GO:0009896 4 0.016
negative regulation of cellular biosynthetic process GO:0031327 55 0.016
hormone secretion GO:0046879 2 0.016
circadian sleep wake cycle process GO:0022410 2 0.016
alcohol metabolic process GO:0006066 11 0.016
regulation of response to stimulus GO:0048583 269 0.016
regulation of intracellular ph GO:0051453 1 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
single fertilization GO:0007338 3 0.016
neuron neuron synaptic transmission GO:0007270 1 0.016
response to glucose GO:0009749 3 0.016
nik nf kappab signaling GO:0038061 1 0.016
exocrine pancreas development GO:0031017 28 0.016
wnt signaling pathway GO:0016055 80 0.016
muscle cell differentiation GO:0042692 139 0.016
response to organic substance GO:0010033 153 0.016
regulation of hormone levels GO:0010817 21 0.015
light absorption GO:0016037 2 0.015
positive regulation of metabolic process GO:0009893 108 0.015
cell cell junction organization GO:0045216 10 0.015
response to vitamin GO:0033273 3 0.015
neuron development GO:0048666 262 0.015
cell migration GO:0016477 237 0.015
nucleobase containing compound metabolic process GO:0006139 274 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
lipid storage GO:0019915 1 0.015
mitochondrion organization GO:0007005 4 0.015
response to glucocorticoid GO:0051384 1 0.015
meiotic cell cycle process GO:1903046 3 0.014
sensory organ development GO:0007423 393 0.014
peripheral nervous system development GO:0007422 55 0.014
cell death GO:0008219 121 0.014
post embryonic foregut morphogenesis GO:0048618 3 0.014
response to biotic stimulus GO:0009607 97 0.014
positive regulation of signaling GO:0023056 56 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
segmentation GO:0035282 97 0.014
g2 m transition of mitotic cell cycle GO:0000086 4 0.014
regulation of cell cycle GO:0051726 52 0.014
cellular amine metabolic process GO:0044106 2 0.014
rna metabolic process GO:0016070 219 0.014
carbohydrate homeostasis GO:0033500 1 0.014
acylglycerol homeostasis GO:0055090 2 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
response to nitrogen compound GO:1901698 19 0.014
phosphorus metabolic process GO:0006793 109 0.014
apical junction assembly GO:0043297 1 0.014
regulation of protein complex assembly GO:0043254 3 0.014
response to lipid GO:0033993 60 0.014
muscle structure development GO:0061061 196 0.014
cell adhesion GO:0007155 40 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
gtp catabolic process GO:0006184 2 0.014
regulation of intracellular protein transport GO:0033157 3 0.013
growth plate cartilage morphogenesis GO:0003422 1 0.013
cellular response to steroid hormone stimulus GO:0071383 31 0.013
regulation of protein targeting GO:1903533 2 0.013
regeneration GO:0031099 91 0.013
amino acid transport GO:0006865 2 0.013
protein polymerization GO:0051258 4 0.013
response to oxygen containing compound GO:1901700 55 0.013
collagen fibril organization GO:0030199 1 0.013
erythrocyte development GO:0048821 24 0.013
astrocyte differentiation GO:0048708 1 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
negative regulation of gene expression GO:0010629 65 0.013
gastrulation GO:0007369 208 0.013
transport GO:0006810 220 0.013
er nucleus signaling pathway GO:0006984 2 0.013
sequestering of calcium ion GO:0051208 3 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
calcium mediated signaling GO:0019722 2 0.013
behavior GO:0007610 74 0.013
regulation of catalytic activity GO:0050790 55 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
response to endogenous stimulus GO:0009719 83 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
cellular protein metabolic process GO:0044267 129 0.012
regulation of cellular ph GO:0030641 1 0.012
mononuclear cell proliferation GO:0032943 1 0.012
cell motility GO:0048870 244 0.012
striated muscle cell development GO:0055002 108 0.012
response to corticosteroid GO:0031960 1 0.012
autophagy GO:0006914 4 0.012
iron ion homeostasis GO:0055072 4 0.012
positive regulation of lipid metabolic process GO:0045834 1 0.012
response to hydrogen peroxide GO:0042542 3 0.012
negative regulation of feeding behavior GO:2000252 2 0.012
cognition GO:0050890 1 0.012
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.012
auditory receptor cell fate commitment GO:0009912 4 0.012
developmental programmed cell death GO:0010623 4 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.012
ion transmembrane transport GO:0034220 91 0.012
secondary metabolic process GO:0019748 3 0.012
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.012
myeloid cell differentiation GO:0030099 86 0.012
negative regulation of transcription dna templated GO:0045892 45 0.012
oxoacid metabolic process GO:0043436 31 0.012
response to methanol GO:0033986 4 0.012
positive regulation of cytokine production GO:0001819 2 0.012
regulation of mesenchymal cell proliferation GO:0010464 1 0.012
interspecies interaction between organisms GO:0044419 4 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
cell cycle g2 m phase transition GO:0044839 4 0.012
response to other organism GO:0051707 97 0.012
sensory system development GO:0048880 76 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
regulation of tube size GO:0035150 2 0.011
cell proliferation GO:0008283 80 0.011
cellular response to organic cyclic compound GO:0071407 38 0.011
b cell activation GO:0042113 2 0.011
regulation of cysteine type endopeptidase activity GO:2000116 21 0.011
dicarboxylic acid transport GO:0006835 1 0.011
cardiocyte differentiation GO:0035051 44 0.011
hormone metabolic process GO:0042445 19 0.011
single organism organelle organization GO:1902589 199 0.011
organelle fission GO:0048285 23 0.011
leukocyte proliferation GO:0070661 1 0.011
immune system development GO:0002520 191 0.011
locomotion GO:0040011 313 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
somite development GO:0061053 96 0.011
organelle assembly GO:0070925 110 0.011
ossification GO:0001503 23 0.011
regulation of protein polymerization GO:0032271 2 0.011
oxidation reduction process GO:0055114 41 0.011
rhodopsin mediated signaling pathway GO:0016056 1 0.011
response to xenobiotic stimulus GO:0009410 45 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
small molecule catabolic process GO:0044282 3 0.011
regulation of neurotransmitter levels GO:0001505 5 0.011
regulation of protein transport GO:0051223 3 0.011
actin mediated cell contraction GO:0070252 1 0.011
signal transduction in absence of ligand GO:0038034 1 0.010
peptide transport GO:0015833 1 0.010
epithelial cell migration GO:0010631 25 0.010
apoptotic signaling pathway GO:0097190 23 0.010
alcohol biosynthetic process GO:0046165 2 0.010
regulation of reproductive process GO:2000241 4 0.010
post anal tail morphogenesis GO:0036342 19 0.010
spindle assembly GO:0051225 2 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
neuroblast proliferation GO:0007405 2 0.010
regulation of histone methylation GO:0031060 3 0.010
calcium ion import GO:0070509 4 0.010
negative regulation of multicellular organismal process GO:0051241 69 0.010
regulation of bmp signaling pathway GO:0030510 39 0.010
organonitrogen compound metabolic process GO:1901564 74 0.010
cellular response to reactive oxygen species GO:0034614 2 0.010
epithelial cell morphogenesis GO:0003382 2 0.010
negative regulation of rna biosynthetic process GO:1902679 45 0.010
negative regulation of multi organism process GO:0043901 3 0.010
regulation of hormone secretion GO:0046883 2 0.010
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 3 0.010
regulation of cellular ketone metabolic process GO:0010565 7 0.010

ela2l disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
artery disease DOID:0050828 0 0.013
vascular disease DOID:178 0 0.013
cardiovascular system disease DOID:1287 0 0.013
nervous system disease DOID:863 0 0.012
disease of metabolism DOID:0014667 0 0.010