Danio rerio

34 known processes

msxc

muscle segment homeobox C

(Aliases: zgc:86596,homeobox,msh-C,mshC,msx-c)

msxc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
otic vesicle morphogenesis GO:0071600 34 0.979
appendage development GO:0048736 80 0.955
Fly
sensory organ morphogenesis GO:0090596 200 0.954
otic vesicle formation GO:0030916 27 0.945
inner ear morphogenesis GO:0042472 63 0.930
embryonic limb morphogenesis GO:0030326 2 0.929
inner ear development GO:0048839 126 0.927
cell fate specification GO:0001708 68 0.918
Fly
ear morphogenesis GO:0042471 64 0.895
sensory organ development GO:0007423 393 0.894
cellular aromatic compound metabolic process GO:0006725 295 0.889
Mouse
gliogenesis GO:0042063 45 0.870
Fly
endocardial cushion formation GO:0003272 2 0.866
nitrogen compound metabolic process GO:0006807 319 0.866
Mouse
determination of left right symmetry GO:0007368 179 0.865
regulation of transcription involved in cell fate commitment GO:0060850 1 0.865
mesoderm morphogenesis GO:0048332 51 0.852
retina development in camera type eye GO:0060041 146 0.839
determination of bilateral symmetry GO:0009855 204 0.830
cell fate commitment GO:0045165 99 0.819
Fly
otic vesicle development GO:0071599 42 0.811
brain development GO:0007420 293 0.811
Fly
septum transversum development GO:0003343 4 0.809
locomotion GO:0040011 313 0.754
Worm
embryonic organ morphogenesis GO:0048562 274 0.742
neuron development GO:0048666 262 0.718
mesodermal cell differentiation GO:0048333 21 0.690
digestive tract development GO:0048565 265 0.674
anterior posterior axon guidance GO:0033564 5 0.635
cardiogenic plate morphogenesis GO:0003142 1 0.626
neuron fate specification GO:0048665 20 0.613
mesoderm development GO:0007498 88 0.612
embryonic skeletal system morphogenesis GO:0048704 93 0.605
Zebrafish
camera type eye development GO:0043010 222 0.589
odontogenesis of dentin containing tooth GO:0042475 1 0.587
ectodermal placode development GO:0071696 37 0.587
positive regulation of endothelial cell differentiation GO:0045603 2 0.586
otic placode formation GO:0043049 23 0.582
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.581
mesodermal cell fate specification GO:0007501 12 0.579
neural precursor cell proliferation GO:0061351 20 0.566
cellular biosynthetic process GO:0044249 286 0.555
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.553
Mouse
proepicardium development GO:0003342 4 0.546
ear development GO:0043583 127 0.546
camera type eye morphogenesis GO:0048593 108 0.545
stem cell proliferation GO:0072089 4 0.535
chordate embryonic development GO:0043009 271 0.513
Zebrafish
limb bud formation GO:0060174 2 0.512
regulation of oligodendrocyte differentiation GO:0048713 1 0.510
endocardial cushion morphogenesis GO:0003203 3 0.508
regulation of transcription dna templated GO:0006355 213 0.496
Mouse
gland development GO:0048732 143 0.495
regulation of chondrocyte differentiation GO:0032330 1 0.480
macromolecule biosynthetic process GO:0009059 227 0.479
Mouse
positive regulation of biological process GO:0048518 253 0.476
regulation of mesodermal cell fate specification GO:0042661 9 0.463
glial cell differentiation GO:0010001 42 0.454
Fly
skeletal system morphogenesis GO:0048705 102 0.454
Zebrafish
regulation of cell fate specification GO:0042659 20 0.453
Fly
regulation of cell fate commitment GO:0010453 22 0.452
Fly
regulation of rna biosynthetic process GO:2001141 213 0.440
Mouse
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.419
cell motility GO:0048870 244 0.414
digestive system development GO:0055123 289 0.412
heart development GO:0007507 313 0.412
cellular nitrogen compound metabolic process GO:0034641 290 0.404
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.402
Mouse
signal transduction GO:0007165 455 0.401
regulation of glial cell differentiation GO:0045685 4 0.401
cell migration GO:0016477 237 0.399
skeletal system development GO:0001501 181 0.396
Zebrafish
mitotic cell cycle GO:0000278 64 0.392
rhombomere development GO:0021546 19 0.391
neuron fate commitment GO:0048663 26 0.387
endocardium morphogenesis GO:0003160 4 0.387
embryonic organ development GO:0048568 381 0.384
central nervous system development GO:0007417 387 0.381
Fly
fin development GO:0033333 77 0.380
mesodermal cell fate commitment GO:0001710 14 0.376
nucleic acid templated transcription GO:0097659 181 0.371
Mouse
regulation of metabolic process GO:0019222 359 0.365
Mouse Fly
cell migration involved in heart development GO:0060973 22 0.363
embryonic viscerocranium morphogenesis GO:0048703 52 0.362
Zebrafish
ectodermal placode formation GO:0060788 26 0.356
specification of symmetry GO:0009799 204 0.355
embryonic skeletal system development GO:0048706 97 0.354
Zebrafish
neuron differentiation GO:0030182 353 0.348
auditory receptor cell fate determination GO:0042668 2 0.339
regulation of macromolecule biosynthetic process GO:0010556 225 0.335
Mouse
pituitary gland development GO:0021983 16 0.333
nucleic acid metabolic process GO:0090304 244 0.332
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.324
Mouse
auditory receptor cell fate commitment GO:0009912 4 0.301
cranial suture morphogenesis GO:0060363 1 0.300
endocardial cushion development GO:0003197 6 0.294
cell migration involved in gastrulation GO:0042074 79 0.294
transcription dna templated GO:0006351 181 0.291
Mouse
response to stress GO:0006950 263 0.291
Zebrafish
dorsal ventral pattern formation GO:0009953 125 0.290
Zebrafish Fly
determination of intestine left right asymmetry GO:0071908 2 0.289
tube morphogenesis GO:0035239 349 0.286
ectodermal placode morphogenesis GO:0071697 32 0.285
embryonic pectoral fin morphogenesis GO:0035118 24 0.285
regulation of endodermal cell fate specification GO:0042663 15 0.284
formation of primary germ layer GO:0001704 62 0.284
pericardium morphogenesis GO:0003344 1 0.284
mesenchymal cell differentiation GO:0048762 87 0.282
regionalization GO:0003002 274 0.280
Zebrafish Fly
mesoderm formation GO:0001707 43 0.279
positive regulation of neural precursor cell proliferation GO:2000179 1 0.275
biosynthetic process GO:0009058 294 0.271
Mouse
regulation of rna metabolic process GO:0051252 224 0.270
Mouse
negative regulation of wnt signaling pathway involved in heart development GO:0003308 2 0.268
determination of heart left right asymmetry GO:0061371 117 0.268
regulation of anatomical structure morphogenesis GO:0022603 130 0.257
semicircular canal formation GO:0060876 4 0.252
bmp signaling pathway GO:0030509 52 0.250
central nervous system neuron differentiation GO:0021953 74 0.244
regulation of mesoderm development GO:2000380 11 0.244
proximal distal pattern formation GO:0009954 1 0.238
neural tube formation GO:0001841 16 0.237
cell morphogenesis GO:0000902 289 0.232
cartilage development GO:0051216 96 0.229
mesenchyme morphogenesis GO:0072132 5 0.229
craniofacial suture morphogenesis GO:0097094 2 0.227
somitogenesis GO:0001756 87 0.223
nucleobase containing compound metabolic process GO:0006139 274 0.222
Mouse
negative regulation of cellular biosynthetic process GO:0031327 55 0.221
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.220
Mouse
rhombomere 5 development GO:0021571 4 0.220
regulation of biosynthetic process GO:0009889 250 0.218
Mouse
fin morphogenesis GO:0033334 53 0.206
morphogenesis of an epithelium GO:0002009 333 0.206
heterocycle metabolic process GO:0046483 290 0.205
Mouse
regulation of cellular metabolic process GO:0031323 320 0.204
Mouse
cell cycle GO:0007049 93 0.203
regulation of primary metabolic process GO:0080090 311 0.203
Mouse
inner ear receptor cell development GO:0060119 20 0.201
pons development GO:0021548 11 0.200
neuroblast proliferation GO:0007405 2 0.200
regulation of programmed cell death GO:0043067 101 0.200
Zebrafish
regulation of stem cell proliferation GO:0072091 2 0.199
cell projection organization GO:0030030 284 0.198
embryonic appendage morphogenesis GO:0035113 30 0.197
epithelial cell differentiation GO:0030855 116 0.197
negative regulation of transcription dna templated GO:0045892 45 0.196
Mouse
cilium morphogenesis GO:0060271 85 0.193
regulation of multicellular organismal development GO:2000026 223 0.192
epithelial to mesenchymal transition GO:0001837 21 0.191
neuroepithelial cell differentiation GO:0060563 26 0.190
neural crest cell differentiation GO:0014033 72 0.190
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.187
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 45 0.187
Mouse
neural tube patterning GO:0021532 33 0.185
regulation of nervous system development GO:0051960 90 0.185
regulation of nucleic acid templated transcription GO:1903506 213 0.185
Mouse
positive regulation of cell differentiation GO:0045597 30 0.183
neural tube development GO:0021915 62 0.182
regulation of epithelial to mesenchymal transition GO:0010717 3 0.182
erythrocyte differentiation GO:0030218 54 0.181
convergent extension GO:0060026 118 0.181
dorsal convergence GO:0060030 14 0.181
ketone biosynthetic process GO:0042181 2 0.178
eye morphogenesis GO:0048592 144 0.178
programmed cell death GO:0012501 119 0.176
Zebrafish Worm
pharyngeal system development GO:0060037 18 0.175
appendage morphogenesis GO:0035107 56 0.174
Fly
olfactory lobe development GO:0021988 4 0.173
connective tissue development GO:0061448 99 0.173
medial fin morphogenesis GO:0035141 14 0.171
brain morphogenesis GO:0048854 18 0.171
dorsal ventral axis specification GO:0009950 14 0.164
pectoral fin development GO:0033339 50 0.164
determination of dorsal ventral asymmetry GO:0048262 34 0.162
rhombomere morphogenesis GO:0021593 17 0.162
specification of axis polarity GO:0065001 4 0.161
somite development GO:0061053 96 0.160
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.159
regulation of sequestering of calcium ion GO:0051282 4 0.159
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.157
cell fate specification involved in pattern specification GO:0060573 3 0.156
organic substance biosynthetic process GO:1901576 289 0.155
Mouse
negative regulation of muscle tissue development GO:1901862 2 0.154
negative regulation of cell fate specification GO:0009996 11 0.153
organic cyclic compound metabolic process GO:1901360 301 0.151
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.150
generation of neurons GO:0048699 385 0.149
atrial ventricular junction remodeling GO:0003294 2 0.145
retina morphogenesis in camera type eye GO:0060042 79 0.145
negative regulation of striated muscle tissue development GO:0045843 2 0.145
skeletal muscle organ development GO:0060538 78 0.143
reproductive process GO:0022414 40 0.140
Worm Fly
intermediate mesoderm development GO:0048389 2 0.140
adenohypophysis development GO:0021984 15 0.140
nucleobase containing compound biosynthetic process GO:0034654 205 0.139
Mouse
regulation of dna replication GO:0006275 3 0.137
negative regulation of cell fate commitment GO:0010454 13 0.136
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.135
embryonic cranial skeleton morphogenesis GO:0048701 90 0.133
Zebrafish
astrocyte differentiation GO:0048708 1 0.132
regulation of macromolecule metabolic process GO:0060255 317 0.130
Mouse Fly
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.130
neural crest cell development GO:0014032 62 0.130
positive regulation of cellular process GO:0048522 201 0.129
tissue regeneration GO:0042246 74 0.129
Zebrafish
cellular component movement GO:0006928 335 0.129
cell proliferation in forebrain GO:0021846 3 0.128
stem cell differentiation GO:0048863 117 0.128
head development GO:0060322 303 0.127
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.127
Mouse
localization of cell GO:0051674 244 0.127
single organism organelle organization GO:1902589 199 0.126
Mouse
nephron morphogenesis GO:0072028 2 0.126
forebrain regionalization GO:0021871 4 0.124
neuron projection guidance GO:0097485 86 0.124
notch signaling pathway GO:0007219 35 0.123
neuron projection morphogenesis GO:0048812 161 0.121
organelle organization GO:0006996 227 0.120
Mouse
limb development GO:0060173 8 0.119
negative regulation of striated muscle cell differentiation GO:0051154 1 0.118
transcription from rna polymerase ii promoter GO:0006366 80 0.118
Mouse
apoptotic process GO:0006915 116 0.117
Zebrafish Worm
medial fin development GO:0033338 16 0.116
positive regulation of epithelial cell proliferation GO:0050679 1 0.116
anterior posterior pattern specification GO:0009952 152 0.115
lateral line nerve development GO:0048892 9 0.114
spinal cord development GO:0021510 46 0.113
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.113
positive regulation of stem cell proliferation GO:2000648 1 0.112
regulation of gastrulation GO:0010470 24 0.112
enzyme linked receptor protein signaling pathway GO:0007167 106 0.111
negative regulation of metabolic process GO:0009892 86 0.110
Mouse Fly
hindbrain development GO:0030902 91 0.109
rna biosynthetic process GO:0032774 181 0.109
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.109
Mouse
bone development GO:0060348 14 0.108
regulation of cell proliferation GO:0042127 37 0.107
olfactory placode development GO:0071698 12 0.106
single organism nuclear import GO:1902593 3 0.106
embryonic heart tube formation GO:0003144 1 0.104
eye development GO:0001654 277 0.104
photoreceptor cell development GO:0042461 40 0.104
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.103
negative regulation of endodermal cell fate specification GO:0042664 8 0.102
negative regulation of axon guidance GO:1902668 1 0.102
morphogenesis of embryonic epithelium GO:0016331 30 0.102
positive regulation of developmental process GO:0051094 50 0.102
semicircular canal development GO:0060872 24 0.101
epithalamus development GO:0021538 10 0.100
wound healing GO:0042060 90 0.100
Zebrafish
heart field specification GO:0003128 1 0.099
stem cell division GO:0017145 1 0.098
mesodermal cell migration GO:0008078 12 0.097
angiogenesis GO:0001525 158 0.097
bmp signaling pathway involved in heart development GO:0061312 15 0.096
bmp signaling pathway involved in heart jogging GO:0003303 14 0.096
photoreceptor cell differentiation GO:0046530 55 0.094
heart morphogenesis GO:0003007 156 0.092
cell surface receptor signaling pathway GO:0007166 325 0.092
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.090
Mouse
mesenchyme development GO:0060485 127 0.089
regulation of cell communication GO:0010646 232 0.089
midbrain hindbrain boundary development GO:0030917 23 0.089
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.087
multicellular organismal reproductive process GO:0048609 35 0.087
Worm
facial nucleus development GO:0021754 7 0.087
negative regulation of macromolecule metabolic process GO:0010605 76 0.085
Mouse Fly
regulation of intracellular protein transport GO:0033157 3 0.083
optic placode formation GO:0001743 4 0.083
mitotic cell cycle process GO:1903047 48 0.082
gastrulation with mouth forming second GO:0001702 44 0.081
macromolecular complex subunit organization GO:0043933 74 0.080
Mouse
positive regulation of epithelial cell differentiation GO:0030858 2 0.080
morphogenesis of an epithelial fold GO:0060571 1 0.079
embryo development ending in birth or egg hatching GO:0009792 271 0.078
Zebrafish
primary neural tube formation GO:0014020 1 0.078
regulation of embryonic development GO:0045995 47 0.078
regulation of cell division GO:0051302 12 0.077
negative regulation of cell adhesion GO:0007162 6 0.076
myeloid cell differentiation GO:0030099 86 0.076
rhombomere 4 development GO:0021570 5 0.076
ameboidal type cell migration GO:0001667 143 0.076
epidermis development GO:0008544 48 0.075
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.075
retinal cone cell development GO:0046549 8 0.075
hematopoietic or lymphoid organ development GO:0048534 191 0.075
positive regulation of rna metabolic process GO:0051254 59 0.075
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.075
regulation of epithelial cell proliferation GO:0050678 3 0.074
negative regulation of biological process GO:0048519 304 0.074
Mouse Fly
heart jogging GO:0003146 40 0.073
epidermal cell differentiation GO:0009913 36 0.073
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.073
embryonic camera type eye development GO:0031076 29 0.073
positive regulation of cell death GO:0010942 29 0.070
positive regulation of nervous system development GO:0051962 25 0.070
negative regulation of histone modification GO:0031057 1 0.069
Mouse
positive regulation of cell proliferation GO:0008284 15 0.069
organic cyclic compound biosynthetic process GO:1901362 223 0.068
Mouse
regulation of gene expression GO:0010468 265 0.068
Mouse Fly
negative regulation of nuclear division GO:0051784 3 0.068
homeostasis of number of cells GO:0048872 62 0.068
regulation of cell cell adhesion GO:0022407 13 0.067
optic placode formation involved in camera type eye formation GO:0046619 3 0.066
regulation of cell differentiation GO:0045595 142 0.066
Fly
rostrocaudal neural tube patterning GO:0021903 29 0.066
regulation of stem cell differentiation GO:2000736 4 0.065
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.065
Mouse
stem cell development GO:0048864 82 0.065
negative regulation of embryonic development GO:0045992 11 0.064
alcohol biosynthetic process GO:0046165 2 0.064
rna metabolic process GO:0016070 219 0.064
Mouse
negative regulation of gliogenesis GO:0014014 1 0.063
mesenchymal cell development GO:0014031 78 0.063
epithelial tube morphogenesis GO:0060562 148 0.062
negative regulation of cell migration GO:0030336 17 0.062
response to mechanical stimulus GO:0009612 24 0.062
cell differentiation in spinal cord GO:0021515 40 0.061
regulation of wnt signaling pathway involved in heart development GO:0003307 2 0.060
regulation of response to stimulus GO:0048583 269 0.060
neural nucleus development GO:0048857 15 0.060
single organism localization GO:1902578 225 0.060
rhombomere formation GO:0021594 12 0.060
regulation of biological quality GO:0065008 263 0.060
retinal rod cell development GO:0046548 4 0.059
negative regulation of neurogenesis GO:0050768 20 0.059
positive regulation of cell communication GO:0010647 56 0.059
tube formation GO:0035148 25 0.058
single organism metabolic process GO:0044710 217 0.058
Mouse
neural retina development GO:0003407 49 0.058
cell part morphogenesis GO:0032990 246 0.058
regulation of skeletal muscle tissue development GO:0048641 4 0.058
homeostatic process GO:0042592 142 0.058
rhombomere 6 development GO:0021572 4 0.057
pharyngeal muscle development GO:0043282 4 0.057
axis specification GO:0009798 43 0.057
nephron epithelium morphogenesis GO:0072088 1 0.057
lymphocyte proliferation GO:0046651 1 0.057
regulation of signal transduction GO:0009966 225 0.056
cell migration involved in heart formation GO:0060974 10 0.055
epithelial cell fate commitment GO:0072148 11 0.055
posterior lateral line neuromast development GO:0048919 20 0.055
regulation of cell migration GO:0030334 40 0.055
regulation of cellular ketone metabolic process GO:0010565 7 0.054
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.054
pancreas development GO:0031016 84 0.054
heart formation GO:0060914 13 0.054
embryonic skeletal joint morphogenesis GO:0060272 3 0.052
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.052
regulation of cellular response to growth factor stimulus GO:0090287 35 0.052
positive regulation of multicellular organismal process GO:0051240 52 0.052
endochondral bone morphogenesis GO:0060350 8 0.052
single organism reproductive process GO:0044702 40 0.051
Worm Fly
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.051
specification of organ position GO:0010159 3 0.051
osteoblast differentiation GO:0001649 5 0.051
negative regulation of signal transduction GO:0009968 94 0.050
lens development in camera type eye GO:0002088 22 0.050
eye photoreceptor cell development GO:0042462 30 0.050
polarized epithelial cell differentiation GO:0030859 4 0.050
liver development GO:0001889 96 0.050
forebrain morphogenesis GO:0048853 6 0.050
regulation of localization GO:0032879 104 0.049
regulation of alcohol biosynthetic process GO:1902930 1 0.049
mesenchymal cell proliferation GO:0010463 1 0.049
auditory receptor cell fate specification GO:0042667 2 0.049
cranial nerve development GO:0021545 42 0.049
cell death GO:0008219 121 0.049
Zebrafish Worm
positive regulation of biosynthetic process GO:0009891 68 0.049
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.048
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.048
response to wounding GO:0009611 116 0.048
Zebrafish
eye photoreceptor cell differentiation GO:0001754 45 0.047
cellular hormone metabolic process GO:0034754 19 0.046
axis elongation GO:0003401 31 0.046
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.045
forebrain generation of neurons GO:0021872 14 0.045
regulation of cartilage development GO:0061035 7 0.045
regulation of signaling GO:0023051 235 0.045
endocardium formation GO:0060214 1 0.045
positive regulation of gene expression GO:0010628 71 0.045
limb morphogenesis GO:0035108 7 0.044
endodermal cell differentiation GO:0035987 19 0.044
determination of dorsal identity GO:0048263 13 0.044
apoptotic process involved in morphogenesis GO:0060561 2 0.044
negative regulation of gastrulation GO:2000542 11 0.044
meiotic nuclear division GO:0007126 4 0.043
developmental process involved in reproduction GO:0003006 27 0.043
Worm Fly
cell proliferation in hindbrain GO:0021534 4 0.043
apoptotic process involved in development GO:1902742 2 0.042
tissue remodeling GO:0048771 4 0.042
embryonic heart tube morphogenesis GO:0003143 108 0.042
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.041
Mouse
negative regulation of rna biosynthetic process GO:1902679 45 0.041
Mouse
anal fin morphogenesis GO:0035144 1 0.041
neural crest cell migration GO:0001755 42 0.041
peripheral nervous system development GO:0007422 55 0.041
regulation of bmp signaling pathway GO:0030510 39 0.041
cell division GO:0051301 20 0.041
negative regulation of rna metabolic process GO:0051253 48 0.041
Mouse
regulation of axonogenesis GO:0050770 32 0.041
ossification GO:0001503 23 0.040
positive regulation of macromolecule metabolic process GO:0010604 93 0.040
diencephalon morphogenesis GO:0048852 5 0.040
negative regulation of gene expression GO:0010629 65 0.040
Mouse Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.040
Mouse
positive regulation of apoptotic process GO:0043065 29 0.040
cell cell signaling involved in cell fate commitment GO:0045168 12 0.039
positive regulation of transcription dna templated GO:0045893 57 0.039
regulation of insulin like growth factor receptor signaling pathway GO:0043567 1 0.039
spinal cord dorsal ventral patterning GO:0021513 5 0.039
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.039
Worm
central nervous system myelin formation GO:0032289 1 0.039
inner ear receptor cell fate commitment GO:0060120 4 0.039
positive regulation of metabolic process GO:0009893 108 0.039
developmental programmed cell death GO:0010623 4 0.038
aging GO:0007568 2 0.038
negative regulation of cellular metabolic process GO:0031324 77 0.038
Mouse
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.038
developmental induction GO:0031128 10 0.038
negative regulation of cell development GO:0010721 26 0.037
positive regulation of cell development GO:0010720 25 0.037
oligodendrocyte differentiation GO:0048709 23 0.037
aromatic compound biosynthetic process GO:0019438 217 0.037
Mouse
organ formation GO:0048645 17 0.036
auditory receptor cell differentiation GO:0042491 15 0.036
embryonic digestive tract morphogenesis GO:0048557 3 0.036
muscle structure development GO:0061061 196 0.036
system process GO:0003008 185 0.036
regulation of developmental process GO:0050793 247 0.036
Fly
regulation of apoptotic process GO:0042981 98 0.036
Zebrafish
positive regulation of cell division GO:0051781 2 0.036
negative regulation of cardiac muscle tissue development GO:0055026 1 0.035
nerve development GO:0021675 45 0.035
multicellular organism reproduction GO:0032504 35 0.035
Worm
gastrulation GO:0007369 208 0.035
cell migration to the midline involved in heart development GO:0003318 12 0.035
regulation of neural precursor cell proliferation GO:2000177 3 0.035
positive regulation of glial cell differentiation GO:0045687 1 0.035
post anal tail morphogenesis GO:0036342 19 0.034
cell projection morphogenesis GO:0048858 244 0.034
embryonic digestive tract development GO:0048566 4 0.034
regulation of endodermal cell differentiation GO:1903224 15 0.034
regeneration GO:0031099 91 0.034
Zebrafish
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.033
positive regulation of rna biosynthetic process GO:1902680 57 0.033
specification of organ identity GO:0010092 2 0.033
regulation of locomotion GO:0040012 55 0.033
negative regulation of developmental process GO:0051093 65 0.033
cytoskeleton organization GO:0007010 96 0.033
death GO:0016265 121 0.033
Zebrafish Worm
gene expression GO:0010467 252 0.033
Mouse Fly
positive regulation of skeletal muscle tissue development GO:0048643 1 0.033
regulation of histone modification GO:0031056 5 0.033
Mouse
response to abiotic stimulus GO:0009628 122 0.032
single organism biosynthetic process GO:0044711 71 0.032
cartilage morphogenesis GO:0060536 13 0.032
muscle organ development GO:0007517 101 0.032
embryonic heart tube development GO:0035050 133 0.032
digestive tract morphogenesis GO:0048546 231 0.032
hindbrain morphogenesis GO:0021575 22 0.032
negative regulation of muscle organ development GO:0048635 5 0.031
semicircular canal morphogenesis GO:0048752 18 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.031
stem cell maintenance GO:0019827 4 0.031
intracellular signal transduction GO:0035556 85 0.030
protein import into nucleus GO:0006606 3 0.030
locomotory behavior GO:0007626 34 0.030
Worm
hepaticobiliary system development GO:0061008 98 0.029
pectoral fin morphogenesis GO:0035138 29 0.029
embryonic epithelial tube formation GO:0001838 17 0.029
microtubule based process GO:0007017 60 0.029
olfactory bulb development GO:0021772 4 0.029
heterocycle biosynthetic process GO:0018130 215 0.028
Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.028
peripheral nervous system neuron differentiation GO:0048934 28 0.028
forebrain development GO:0030900 96 0.028
regulation of canonical wnt signaling pathway GO:0060828 34 0.028
rhombomere boundary formation GO:0021654 10 0.028
axon regeneration GO:0031103 14 0.028
heart looping GO:0001947 94 0.028
otolith development GO:0048840 32 0.028
endodermal cell fate specification GO:0001714 17 0.028
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.028
organonitrogen compound metabolic process GO:1901564 74 0.028

msxc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.311
bone disease DOID:0080001 0 0.311
disease of anatomical entity DOID:7 0 0.311
dysostosis DOID:1934 0 0.311
musculoskeletal system disease DOID:17 0 0.311
connective tissue disease DOID:65 0 0.311
nervous system disease DOID:863 0 0.111
physical disorder DOID:0080015 0 0.053
sensory system disease DOID:0050155 0 0.035