Danio rerio

0 known processes

pepd

peptidase D

(Aliases: wu:fj78g11,fj78g11,cb1000)

pepd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
blood vessel morphogenesis GO:0048514 216 0.286
blood vessel development GO:0001568 246 0.196
angiogenesis GO:0001525 158 0.139
vasculature development GO:0001944 278 0.138
signal transduction GO:0007165 455 0.129
lipid storage GO:0019915 1 0.105
larval development GO:0002164 2 0.097
regulation of multicellular organismal process GO:0051239 277 0.078
gtp metabolic process GO:0046039 4 0.076
autophagy GO:0006914 4 0.075
regulation of signal transduction GO:0009966 225 0.072
maintenance of location GO:0051235 4 0.072
synaptic growth at neuromuscular junction GO:0051124 2 0.070
adult behavior GO:0030534 2 0.063
endosomal transport GO:0016197 2 0.063
cellular aldehyde metabolic process GO:0006081 4 0.059
meiotic cell cycle process GO:1903046 3 0.055
meiotic nuclear division GO:0007126 4 0.054
positive regulation of transport GO:0051050 2 0.054
phagocytosis GO:0006909 3 0.052
cellular protein catabolic process GO:0044257 4 0.050
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.046
lipid catabolic process GO:0016042 4 0.046
establishment of localization GO:0051234 244 0.046
mitochondrion organization GO:0007005 4 0.045
regulation of synapse assembly GO:0051963 3 0.044
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.044
regulation of synapse organization GO:0050807 3 0.043
positive regulation of apoptotic signaling pathway GO:2001235 1 0.042
nitrogen compound metabolic process GO:0006807 319 0.039
cell morphogenesis GO:0000902 289 0.039
single organism metabolic process GO:0044710 217 0.038
positive regulation of cell cycle GO:0045787 3 0.036
single organism transport GO:0044765 206 0.035
multicellular organism growth GO:0035264 4 0.035
positive regulation of cellular catabolic process GO:0031331 3 0.035
regulation of organelle assembly GO:1902115 4 0.034
regulation of protein catabolic process GO:0042176 1 0.034
cellular amine metabolic process GO:0044106 2 0.033
amine metabolic process GO:0009308 2 0.033
organonitrogen compound metabolic process GO:1901564 74 0.033
cytokinesis GO:0000910 3 0.033
guanosine containing compound metabolic process GO:1901068 4 0.033
meiotic chromosome segregation GO:0045132 3 0.032
regulation of signaling GO:0023051 235 0.030
gtp catabolic process GO:0006184 2 0.030
regulation of biological quality GO:0065008 263 0.030
regulation of cellular protein catabolic process GO:1903362 1 0.030
regulation of nitrogen compound metabolic process GO:0051171 251 0.029
ubiquitin dependent protein catabolic process GO:0006511 3 0.029
regulation of cell activation GO:0050865 1 0.029
leukocyte mediated cytotoxicity GO:0001909 1 0.028
protein metabolic process GO:0019538 183 0.027
peptidyl serine modification GO:0018209 2 0.027
response to glucocorticoid GO:0051384 1 0.027
negative regulation of biological process GO:0048519 304 0.027
positive regulation of catabolic process GO:0009896 4 0.026
cellular aromatic compound metabolic process GO:0006725 295 0.026
guanosine containing compound catabolic process GO:1901069 2 0.026
response to corticosteroid GO:0031960 1 0.026
response to organic substance GO:0010033 153 0.026
peptidyl serine phosphorylation GO:0018105 1 0.026
response to chemical GO:0042221 320 0.026
morphogenesis of an epithelium GO:0002009 333 0.026
tube morphogenesis GO:0035239 349 0.025
regulation of cell communication GO:0010646 232 0.025
atp catabolic process GO:0006200 4 0.025
protein import into nucleus GO:0006606 3 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
digestive system development GO:0055123 289 0.024
regulation of metal ion transport GO:0010959 4 0.024
developmental growth GO:0048589 166 0.024
carboxylic acid metabolic process GO:0019752 22 0.024
phosphate containing compound metabolic process GO:0006796 108 0.024
response to stress GO:0006950 263 0.024
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.023
tissue remodeling GO:0048771 4 0.023
positive regulation of striated muscle cell differentiation GO:0051155 1 0.023
regulation of cellular metabolic process GO:0031323 320 0.023
nucleobase containing compound metabolic process GO:0006139 274 0.023
cellular response to chemical stimulus GO:0070887 157 0.022
generation of neurons GO:0048699 385 0.022
phosphorus metabolic process GO:0006793 109 0.022
positive regulation of cell activation GO:0050867 1 0.022
cell surface receptor signaling pathway GO:0007166 325 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.022
vacuolar transport GO:0007034 2 0.021
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
cellular macromolecule metabolic process GO:0044260 391 0.021
establishment of protein localization to organelle GO:0072594 4 0.020
purine nucleoside monophosphate catabolic process GO:0009128 4 0.020
erk1 and erk2 cascade GO:0070371 4 0.020
gastrulation GO:0007369 208 0.020
regulation of erk1 and erk2 cascade GO:0070372 4 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
aging GO:0007568 2 0.020
regulation of macromolecule metabolic process GO:0060255 317 0.019
regulation of primary metabolic process GO:0080090 311 0.019
establishment of rna localization GO:0051236 3 0.019
ion transport GO:0006811 114 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.019
protein targeting to nucleus GO:0044744 3 0.019
regulation of mrna splicing via spliceosome GO:0048024 3 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
nucleic acid transport GO:0050657 2 0.018
response to monosaccharide GO:0034284 3 0.018
regulation of metabolic process GO:0019222 359 0.018
positive regulation of muscle cell differentiation GO:0051149 1 0.018
heterocycle metabolic process GO:0046483 290 0.018
organic acid metabolic process GO:0006082 31 0.018
regulation of catalytic activity GO:0050790 55 0.018
mitotic cytokinesis GO:0000281 3 0.018
regulation of binding GO:0051098 3 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
response to ketone GO:1901654 1 0.018
cell substrate junction assembly GO:0007044 2 0.018
nuclear transport GO:0051169 4 0.018
regulation of developmental process GO:0050793 247 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
regulation of cytokine production GO:0001817 3 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
neuron differentiation GO:0030182 353 0.017
negative regulation of signal transduction GO:0009968 94 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
rna localization GO:0006403 4 0.017
negative regulation of reproductive process GO:2000242 3 0.017
protein acylation GO:0043543 3 0.017
positive regulation of gtp catabolic process GO:0033126 1 0.017
regulation of anatomical structure morphogenesis GO:0022603 130 0.017
positive regulation of secretion GO:0051047 1 0.017
cytoskeleton dependent cytokinesis GO:0061640 3 0.017
single organism localization GO:1902578 225 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
response to hexose GO:0009746 3 0.017
positive regulation of exocytosis GO:0045921 1 0.016
positive regulation of blood circulation GO:1903524 2 0.016
lymphocyte proliferation GO:0046651 1 0.016
regulation of protein transport GO:0051223 3 0.016
death GO:0016265 121 0.016
hemopoiesis GO:0030097 183 0.016
single organism nuclear import GO:1902593 3 0.016
regulation of meiotic cell cycle GO:0051445 1 0.016
alternative mrna splicing via spliceosome GO:0000380 1 0.016
neuron development GO:0048666 262 0.016
compound eye development GO:0048749 2 0.016
regulation of response to stimulus GO:0048583 269 0.016
nucleoside monophosphate catabolic process GO:0009125 4 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
cellular component morphogenesis GO:0032989 336 0.016
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.016
positive regulation of map kinase activity GO:0043406 3 0.016
protein localization to nucleus GO:0034504 3 0.015
positive regulation of cellular process GO:0048522 201 0.015
bone remodeling GO:0046849 2 0.015
regulation of blood pressure GO:0008217 1 0.015
leukocyte proliferation GO:0070661 1 0.015
proteasomal protein catabolic process GO:0010498 2 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
mononuclear cell proliferation GO:0032943 1 0.015
response to carbohydrate GO:0009743 3 0.015
small molecule metabolic process GO:0044281 77 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
intracellular signal transduction GO:0035556 85 0.015
sulfur compound transport GO:0072348 3 0.015
neuron projection development GO:0031175 180 0.015
response to endogenous stimulus GO:0009719 83 0.015
stem cell maintenance GO:0019827 4 0.015
cellular transition metal ion homeostasis GO:0046916 3 0.015
regulation of reproductive process GO:2000241 4 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
regulation of cell shape GO:0008360 1 0.015
digestive tract development GO:0048565 265 0.015
response to glucose GO:0009749 3 0.015
response to hypoxia GO:0001666 25 0.014
somatic muscle development GO:0007525 4 0.014
oxoacid metabolic process GO:0043436 31 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
organic cyclic compound metabolic process GO:1901360 301 0.014
macroautophagy GO:0016236 1 0.014
nuclear import GO:0051170 3 0.014
regulation of multicellular organism growth GO:0040014 4 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
regulation of gtpase activity GO:0043087 2 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
transport GO:0006810 220 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
positive regulation of jnk cascade GO:0046330 3 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
digestive tract morphogenesis GO:0048546 231 0.013
negative regulation of nuclear division GO:0051784 3 0.013
b cell activation GO:0042113 2 0.013
cellular protein modification process GO:0006464 100 0.013
b cell differentiation GO:0030183 1 0.013
tube closure GO:0060606 1 0.013
regulation of reactive oxygen species metabolic process GO:2000377 2 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
regeneration GO:0031099 91 0.013
response to abiotic stimulus GO:0009628 122 0.013
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
membrane fusion GO:0061025 2 0.013
multi organism process GO:0051704 134 0.013
circulatory system process GO:0003013 87 0.013
immune system process GO:0002376 241 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
negative regulation of kinase activity GO:0033673 4 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
cellular biogenic amine metabolic process GO:0006576 2 0.013
biosynthetic process GO:0009058 294 0.013
regulation of cellular component organization GO:0051128 86 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
metal ion transport GO:0030001 58 0.013
positive regulation of translation GO:0045727 1 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.012
negative regulation of protein complex assembly GO:0031333 1 0.012
cellular response to decreased oxygen levels GO:0036294 1 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
cellular response to stress GO:0033554 62 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
regulation of mrna processing GO:0050684 3 0.012
cofactor metabolic process GO:0051186 15 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
regulation of autophagy GO:0010506 3 0.012
cellular protein metabolic process GO:0044267 129 0.012
immune system development GO:0002520 191 0.012
photoreceptor cell outer segment organization GO:0035845 9 0.012
ion transmembrane transport GO:0034220 91 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
recombinational repair GO:0000725 1 0.012
regulation of response to nutrient levels GO:0032107 1 0.012
cell projection organization GO:0030030 284 0.012
liver development GO:0001889 96 0.012
fertilization GO:0009566 3 0.012
single organism organelle organization GO:1902589 199 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
eye development GO:0001654 277 0.012
system process GO:0003008 185 0.011
muscle organ development GO:0007517 101 0.011
dna templated transcription initiation GO:0006352 1 0.011
cation transport GO:0006812 81 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
cell migration involved in gastrulation GO:0042074 79 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
defense response GO:0006952 47 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
golgi vesicle transport GO:0048193 3 0.011
oxidoreduction coenzyme metabolic process GO:0006733 1 0.011
organelle organization GO:0006996 227 0.011
transcription dna templated GO:0006351 181 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
antimicrobial humoral response GO:0019730 2 0.011
regulation of dendrite development GO:0050773 3 0.011
negative regulation of protein phosphorylation GO:0001933 4 0.011
small molecule catabolic process GO:0044282 3 0.011
epithelial cell morphogenesis GO:0003382 2 0.011
apoptotic process involved in development GO:1902742 2 0.011
axon development GO:0061564 166 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
wnt signaling pathway GO:0016055 80 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
regulation of jun kinase activity GO:0043506 3 0.011
regulation of calcium ion transport GO:0051924 2 0.011
protein dephosphorylation GO:0006470 3 0.011
response to biotic stimulus GO:0009607 97 0.011
primary neural tube formation GO:0014020 1 0.011
cellular response to nutrient levels GO:0031669 2 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.010
cellular component assembly GO:0022607 170 0.010
positive regulation of cytokine production GO:0001819 2 0.010
convergent extension GO:0060026 118 0.010
gene expression GO:0010467 252 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
exocytosis GO:0006887 1 0.010
cell proliferation GO:0008283 80 0.010
protein import GO:0017038 3 0.010
regulation of cellular protein metabolic process GO:0032268 52 0.010
mitochondrial transport GO:0006839 2 0.010
cellular nitrogen compound metabolic process GO:0034641 290 0.010

pepd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.121
nervous system disease DOID:863 0 0.045
disease of metabolism DOID:0014667 0 0.038
inherited metabolic disorder DOID:655 0 0.038
musculoskeletal system disease DOID:17 0 0.019
central nervous system disease DOID:331 0 0.017
brain disease DOID:936 0 0.017
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011
immune system disease DOID:2914 0 0.010