Danio rerio

0 known processes

adam9

a disintegrin and metalloproteinase domain 9

(Aliases: zgc:101824)

adam9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.092
embryo development ending in birth or egg hatching GO:0009792 271 0.065
protein localization to nucleus GO:0034504 3 0.064
heart development GO:0007507 313 0.061
larval development GO:0002164 2 0.061
positive regulation of transport GO:0051050 2 0.057
transport GO:0006810 220 0.050
regulation of establishment of protein localization GO:0070201 4 0.043
positive regulation of catabolic process GO:0009896 4 0.043
regulation of protein transport GO:0051223 3 0.040
regulation of cytokine production GO:0001817 3 0.039
nucleocytoplasmic transport GO:0006913 4 0.039
nuclear transport GO:0051169 4 0.038
establishment of localization GO:0051234 244 0.037
single organism nuclear import GO:1902593 3 0.037
cellular component movement GO:0006928 335 0.036
regulation of cellular amine metabolic process GO:0033238 0 0.036
multicellular organism growth GO:0035264 4 0.034
cellular nitrogen compound metabolic process GO:0034641 290 0.034
nitrogen compound metabolic process GO:0006807 319 0.033
regulation of protein localization to nucleus GO:1900180 2 0.033
meiotic nuclear division GO:0007126 4 0.032
regulation of nucleoside metabolic process GO:0009118 2 0.031
regulation of reactive oxygen species metabolic process GO:2000377 2 0.031
positive regulation of cellular catabolic process GO:0031331 3 0.030
regulation of metabolic process GO:0019222 359 0.029
regulation of nucleocytoplasmic transport GO:0046822 2 0.028
locomotion GO:0040011 313 0.028
nuclear import GO:0051170 3 0.028
regulation of multicellular organismal process GO:0051239 277 0.027
regulation of multicellular organism growth GO:0040014 4 0.027
cellular amine metabolic process GO:0044106 2 0.027
regulation of cytoplasmic transport GO:1903649 4 0.027
amine metabolic process GO:0009308 2 0.027
regulation of intracellular protein transport GO:0033157 3 0.026
organelle organization GO:0006996 227 0.026
sleep GO:0030431 1 0.026
single organism localization GO:1902578 225 0.025
maintenance of location GO:0051235 4 0.025
regionalization GO:0003002 274 0.025
response to chemical GO:0042221 320 0.024
lipid storage GO:0019915 1 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.024
positive regulation of cellular amine metabolic process GO:0033240 0 0.024
cellular ketone metabolic process GO:0042180 11 0.023
positive regulation of cell cycle GO:0045787 3 0.023
regulation of response to stimulus GO:0048583 269 0.023
cellular protein catabolic process GO:0044257 4 0.023
protein import GO:0017038 3 0.023
regulation of cell shape GO:0008360 1 0.023
regulation of nucleotide catabolic process GO:0030811 2 0.023
regulation of erk1 and erk2 cascade GO:0070372 4 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
erk1 and erk2 cascade GO:0070371 4 0.022
positive regulation of map kinase activity GO:0043406 3 0.021
nuclear export GO:0051168 1 0.021
cellular component assembly involved in morphogenesis GO:0010927 107 0.021
regulation of purine nucleotide catabolic process GO:0033121 2 0.021
signal transduction GO:0007165 455 0.021
immune system process GO:0002376 241 0.021
negative regulation of catabolic process GO:0009895 3 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
guanosine containing compound metabolic process GO:1901068 4 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.020
negative regulation of protein transport GO:0051224 3 0.020
central nervous system development GO:0007417 387 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.020
positive regulation of secretion GO:0051047 1 0.020
gtp metabolic process GO:0046039 4 0.020
regulation of protein complex assembly GO:0043254 3 0.020
cell substrate adhesion GO:0031589 4 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
proteasomal protein catabolic process GO:0010498 2 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
positive regulation of secretion by cell GO:1903532 1 0.019
regulation of protein targeting GO:1903533 2 0.019
response to topologically incorrect protein GO:0035966 2 0.019
regulation of protein import into nucleus GO:0042306 2 0.019
regulation of muscle contraction GO:0006937 3 0.019
organelle assembly GO:0070925 110 0.019
modification dependent protein catabolic process GO:0019941 3 0.019
camera type eye development GO:0043010 222 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
heterocycle metabolic process GO:0046483 290 0.018
regulation of gtp catabolic process GO:0033124 2 0.018
chordate embryonic development GO:0043009 271 0.018
protein targeting to nucleus GO:0044744 3 0.018
head development GO:0060322 303 0.018
response to monosaccharide GO:0034284 3 0.018
cytoskeleton dependent cytokinesis GO:0061640 3 0.018
regulation of localization GO:0032879 104 0.018
protein import into nucleus GO:0006606 3 0.018
immune system development GO:0002520 191 0.018
positive regulation of cytokine production GO:0001819 2 0.017
cytokinesis GO:0000910 3 0.017
cellular component disassembly GO:0022411 1 0.017
glucose homeostasis GO:0042593 1 0.017
vasculature development GO:0001944 278 0.017
exocytosis GO:0006887 1 0.017
cellular aromatic compound metabolic process GO:0006725 295 0.017
single organism transport GO:0044765 206 0.017
response to glucose GO:0009749 3 0.017
guanosine containing compound catabolic process GO:1901069 2 0.017
phagocytosis GO:0006909 3 0.017
organonitrogen compound metabolic process GO:1901564 74 0.016
regulation of primary metabolic process GO:0080090 311 0.016
negative regulation of cytokine production GO:0001818 1 0.016
sensory organ development GO:0007423 393 0.016
cellular response to molecule of bacterial origin GO:0071219 3 0.016
regulation of gtpase activity GO:0043087 2 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
negative regulation of cellular catabolic process GO:0031330 3 0.016
response to hexose GO:0009746 3 0.016
regulation of blood pressure GO:0008217 1 0.015
protein acylation GO:0043543 3 0.015
regulation of metal ion transport GO:0010959 4 0.015
system process GO:0003008 185 0.015
response to carbohydrate GO:0009743 3 0.015
cellular response to unfolded protein GO:0034620 2 0.015
membrane invagination GO:0010324 1 0.015
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.015
circadian sleep wake cycle GO:0042745 2 0.015
regulation of signaling GO:0023051 235 0.015
muscle cell differentiation GO:0042692 139 0.015
meiotic chromosome segregation GO:0045132 3 0.015
nucleobase containing compound metabolic process GO:0006139 274 0.015
eye morphogenesis GO:0048592 144 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
actin filament based movement GO:0030048 1 0.014
cellular response to external stimulus GO:0071496 2 0.014
regulation of cell activation GO:0050865 1 0.014
eye development GO:0001654 277 0.014
single organism organelle organization GO:1902589 199 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
regulation of inflammatory response GO:0050727 2 0.014
regulation of biological quality GO:0065008 263 0.014
action potential GO:0001508 19 0.014
multi organism process GO:0051704 134 0.014
muscle structure development GO:0061061 196 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
small molecule metabolic process GO:0044281 77 0.014
cellular response to biotic stimulus GO:0071216 3 0.014
tube morphogenesis GO:0035239 349 0.014
regulation of cell substrate adhesion GO:0010810 1 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
gtp catabolic process GO:0006184 2 0.014
neuronal action potential GO:0019228 18 0.014
rna metabolic process GO:0016070 219 0.014
peptidyl serine phosphorylation GO:0018105 1 0.014
angiogenesis GO:0001525 158 0.014
regulation of autophagy GO:0010506 3 0.013
cellular response to starvation GO:0009267 1 0.013
blood vessel morphogenesis GO:0048514 216 0.013
biosynthetic process GO:0009058 294 0.013
cognition GO:0050890 1 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
homeostatic process GO:0042592 142 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
growth GO:0040007 174 0.013
cell motility GO:0048870 244 0.013
organic cyclic compound metabolic process GO:1901360 301 0.013
determination of left right symmetry GO:0007368 179 0.013
cilium morphogenesis GO:0060271 85 0.013
nucleic acid metabolic process GO:0090304 244 0.013
regulation of binding GO:0051098 3 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
positive regulation of cell activation GO:0050867 1 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
response to drug GO:0042493 3 0.013
establishment of localization in cell GO:0051649 77 0.013
carbohydrate homeostasis GO:0033500 1 0.013
regulation of receptor activity GO:0010469 2 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
blood circulation GO:0008015 87 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
positive regulation of biological process GO:0048518 253 0.012
protein acetylation GO:0006473 2 0.012
lymphocyte proliferation GO:0046651 1 0.012
negative regulation of intracellular protein transport GO:0090317 3 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
peptidyl serine modification GO:0018209 2 0.012
response to external biotic stimulus GO:0043207 97 0.012
regulation of protein catabolic process GO:0042176 1 0.012
cell projection assembly GO:0030031 64 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
mitotic cytokinesis GO:0000281 3 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
specification of symmetry GO:0009799 204 0.012
cell projection organization GO:0030030 284 0.012
meiotic cell cycle process GO:1903046 3 0.012
blood vessel development GO:0001568 246 0.012
single organism metabolic process GO:0044710 217 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
oxoacid metabolic process GO:0043436 31 0.012
negative regulation of cellular process GO:0048523 283 0.012
cellular component assembly GO:0022607 170 0.012
defense response to other organism GO:0098542 33 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
regulation of wound healing GO:0061041 2 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
negative regulation of secretion GO:0051048 2 0.012
cell migration GO:0016477 237 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
regulation of ras gtpase activity GO:0032318 2 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
cell matrix adhesion GO:0007160 4 0.012
endoplasmic reticulum unfolded protein response GO:0030968 2 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
aromatic compound biosynthetic process GO:0019438 217 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
cellular component biogenesis GO:0044085 178 0.011
generation of neurons GO:0048699 385 0.011
activation of mapk activity GO:0000187 3 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.011
protein secretion GO:0009306 1 0.011
protein polymerization GO:0051258 4 0.011
regulation of cell matrix adhesion GO:0001952 1 0.011
leukocyte proliferation GO:0070661 1 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
negative regulation of protein localization to nucleus GO:1900181 2 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
establishment of rna localization GO:0051236 3 0.011
gene expression GO:0010467 252 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
somitogenesis GO:0001756 87 0.011
actin cytoskeleton organization GO:0030036 63 0.011
regulation of transporter activity GO:0032409 2 0.011
macromolecular complex disassembly GO:0032984 1 0.011
rna transport GO:0050658 2 0.011
cell morphogenesis GO:0000902 289 0.011
nucleic acid transport GO:0050657 2 0.011
interspecies interaction between organisms GO:0044419 4 0.011
multicellular organismal metabolic process GO:0044236 2 0.011
transmission of nerve impulse GO:0019226 19 0.011
antimicrobial humoral response GO:0019730 2 0.011
nucleobase containing compound transport GO:0015931 2 0.011
response to unfolded protein GO:0006986 2 0.011
response to ketone GO:1901654 1 0.011
anterior posterior pattern specification GO:0009952 152 0.011
organic substance biosynthetic process GO:1901576 289 0.011
regulation of jak stat cascade GO:0046425 3 0.011
negative regulation of protein complex assembly GO:0031333 1 0.011
regulation of cellular metabolic process GO:0031323 320 0.011
negative regulation of defense response GO:0031348 2 0.011
response to organic substance GO:0010033 153 0.011
cellular response to organic substance GO:0071310 105 0.011
response to other organism GO:0051707 97 0.011
response to stress GO:0006950 263 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
regulation of gene expression GO:0010468 265 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
stem cell maintenance GO:0019827 4 0.010
cellular component morphogenesis GO:0032989 336 0.010
response to wounding GO:0009611 116 0.010
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.010
somatic muscle development GO:0007525 4 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010

adam9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.017
musculoskeletal system disease DOID:17 0 0.013
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012