Danio rerio

0 known processes

zgc:153941

zgc:153941

(Aliases: MGC153941,Tnfsf12)

zgc:153941 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.101
immune system process GO:0002376 241 0.089
regulation of cytokine production GO:0001817 3 0.068
aging GO:0007568 2 0.068
cell surface receptor signaling pathway GO:0007166 325 0.065
positive regulation of cytokine production GO:0001819 2 0.063
signal transduction GO:0007165 455 0.056
hematopoietic or lymphoid organ development GO:0048534 191 0.051
lipid storage GO:0019915 1 0.047
amine metabolic process GO:0009308 2 0.046
nuclear transport GO:0051169 4 0.045
regulation of protein transport GO:0051223 3 0.045
nucleocytoplasmic transport GO:0006913 4 0.043
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.042
stem cell proliferation GO:0072089 4 0.041
multicellular organism growth GO:0035264 4 0.041
establishment of protein localization to organelle GO:0072594 4 0.040
positive regulation of transport GO:0051050 2 0.040
protein localization to nucleus GO:0034504 3 0.040
single organism nuclear import GO:1902593 3 0.040
cellular amine metabolic process GO:0044106 2 0.039
regulation of cellular amine metabolic process GO:0033238 0 0.039
cellular response to molecule of bacterial origin GO:0071219 3 0.038
cellular response to lipopolysaccharide GO:0071222 3 0.038
cellular nitrogen compound metabolic process GO:0034641 290 0.038
regulation of multicellular organism growth GO:0040014 4 0.036
response to external stimulus GO:0009605 264 0.036
regulation of gene expression GO:0010468 265 0.035
hemopoiesis GO:0030097 183 0.035
embryonic organ development GO:0048568 381 0.035
protein import into nucleus GO:0006606 3 0.034
cellular ketone metabolic process GO:0042180 11 0.034
regulation of establishment of protein localization GO:0070201 4 0.033
tube morphogenesis GO:0035239 349 0.033
regulation of cellular amino acid metabolic process GO:0006521 0 0.033
regulation of cellular ketone metabolic process GO:0010565 7 0.033
nitrogen compound metabolic process GO:0006807 319 0.032
leukocyte proliferation GO:0070661 1 0.032
immune system development GO:0002520 191 0.032
nuclear import GO:0051170 3 0.032
maintenance of location GO:0051235 4 0.032
female sex differentiation GO:0046660 4 0.032
digestive tract morphogenesis GO:0048546 231 0.031
protein targeting to nucleus GO:0044744 3 0.031
cellular macromolecule metabolic process GO:0044260 391 0.031
regulation of multicellular organismal process GO:0051239 277 0.031
mononuclear cell proliferation GO:0032943 1 0.031
regulation of biological quality GO:0065008 263 0.031
regulation of inflammatory response GO:0050727 2 0.031
multi organism process GO:0051704 134 0.031
response to stress GO:0006950 263 0.031
cellular response to biotic stimulus GO:0071216 3 0.030
cellular response to external stimulus GO:0071496 2 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.030
digestive tract development GO:0048565 265 0.030
response to other organism GO:0051707 97 0.030
regulation of production of molecular mediator of immune response GO:0002700 1 0.030
protein import GO:0017038 3 0.030
gastrulation GO:0007369 208 0.029
pericardium development GO:0060039 1 0.029
response to drug GO:0042493 3 0.029
phagocytosis GO:0006909 3 0.028
positive regulation of cell activation GO:0050867 1 0.028
regulation of response to stimulus GO:0048583 269 0.028
cellular response to chemical stimulus GO:0070887 157 0.028
autophagy GO:0006914 4 0.027
heterocycle metabolic process GO:0046483 290 0.027
biosynthetic process GO:0009058 294 0.027
immunoglobulin mediated immune response GO:0016064 3 0.027
positive regulation of immune effector process GO:0002699 3 0.027
regulation of macromolecule biosynthetic process GO:0010556 225 0.027
nucleobase containing compound biosynthetic process GO:0034654 205 0.026
oxoacid metabolic process GO:0043436 31 0.026
response to bacterium GO:0009617 58 0.026
vasculature development GO:0001944 278 0.026
negative regulation of autophagy GO:0010507 1 0.026
regulation of cell activation GO:0050865 1 0.026
positive regulation of cell cycle GO:0045787 3 0.026
stem cell division GO:0017145 1 0.025
protein metabolic process GO:0019538 183 0.025
enzyme linked receptor protein signaling pathway GO:0007167 106 0.025
cellular biosynthetic process GO:0044249 286 0.025
response to carbohydrate GO:0009743 3 0.025
blood vessel development GO:0001568 246 0.025
b cell activation GO:0042113 2 0.025
small molecule metabolic process GO:0044281 77 0.025
digestive system development GO:0055123 289 0.025
response to external biotic stimulus GO:0043207 97 0.024
regulation of metabolic process GO:0019222 359 0.024
cellular amino acid metabolic process GO:0006520 7 0.024
protein secretion GO:0009306 1 0.024
tissue remodeling GO:0048771 4 0.024
positive regulation of myeloid cell differentiation GO:0045639 2 0.024
positive regulation of cellular amine metabolic process GO:0033240 0 0.024
lymphocyte proliferation GO:0046651 1 0.024
cellular macromolecule biosynthetic process GO:0034645 224 0.024
heterocycle biosynthetic process GO:0018130 215 0.024
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.024
single organism metabolic process GO:0044710 217 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
regulation of developmental process GO:0050793 247 0.023
negative regulation of cytokine production GO:0001818 1 0.023
regulation of binding GO:0051098 3 0.023
morphogenesis of an epithelium GO:0002009 333 0.023
regulation of cellular biosynthetic process GO:0031326 245 0.023
carboxylic acid metabolic process GO:0019752 22 0.022
inositol lipid mediated signaling GO:0048017 2 0.022
response to biotic stimulus GO:0009607 97 0.022
cell cycle g1 s phase transition GO:0044843 1 0.022
positive regulation of stress activated mapk cascade GO:0032874 3 0.022
regulation of cellular metabolic process GO:0031323 320 0.022
protein acetylation GO:0006473 2 0.022
regulation of reactive oxygen species metabolic process GO:2000377 2 0.022
transcription dna templated GO:0006351 181 0.022
regulation of biosynthetic process GO:0009889 250 0.022
stem cell maintenance GO:0019827 4 0.022
organic substance biosynthetic process GO:1901576 289 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.021
blood vessel morphogenesis GO:0048514 216 0.021
positive regulation of biological process GO:0048518 253 0.021
production of molecular mediator of immune response GO:0002440 2 0.021
regulation of rna biosynthetic process GO:2001141 213 0.020
positive regulation of dna metabolic process GO:0051054 1 0.020
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.020
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.020
establishment of localization GO:0051234 244 0.020
regulation of tube size GO:0035150 2 0.020
organic acid metabolic process GO:0006082 31 0.020
transcription from rna polymerase ii promoter GO:0006366 80 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.020
regulation of protein import into nucleus GO:0042306 2 0.020
cellular response to nutrient levels GO:0031669 2 0.020
complement activation GO:0006956 3 0.020
g1 s transition of mitotic cell cycle GO:0000082 1 0.020
positive regulation of secretion by cell GO:1903532 1 0.020
response to wounding GO:0009611 116 0.020
negative regulation of catabolic process GO:0009895 3 0.020
nucleic acid metabolic process GO:0090304 244 0.020
organic cyclic compound metabolic process GO:1901360 301 0.020
positive regulation of secretion GO:0051047 1 0.020
synaptic transmission cholinergic GO:0007271 4 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
b cell mediated immunity GO:0019724 3 0.019
female gonad development GO:0008585 4 0.019
negative regulation of cellular catabolic process GO:0031330 3 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
nucleic acid templated transcription GO:0097659 181 0.019
response to chemical GO:0042221 320 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
angiogenesis GO:0001525 158 0.019
regulation of protein targeting GO:1903533 2 0.019
cell motility GO:0048870 244 0.019
regulation of cell communication GO:0010646 232 0.019
regulation of ph GO:0006885 3 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
positive regulation of map kinase activity GO:0043406 3 0.019
regulation of rna metabolic process GO:0051252 224 0.018
phosphatidylinositol mediated signaling GO:0048015 2 0.018
development of primary female sexual characteristics GO:0046545 4 0.018
rna biosynthetic process GO:0032774 181 0.018
gtp metabolic process GO:0046039 4 0.018
internal peptidyl lysine acetylation GO:0018393 2 0.018
regulation of autophagy GO:0010506 3 0.018
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.018
protein acylation GO:0043543 3 0.018
positive regulation of leukocyte mediated immunity GO:0002705 1 0.018
response to vitamin GO:0033273 3 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
response to corticosteroid GO:0031960 1 0.018
regulation of stem cell proliferation GO:0072091 2 0.018
single organism transport GO:0044765 206 0.017
rna metabolic process GO:0016070 219 0.017
cell migration GO:0016477 237 0.017
regulation of signal transduction GO:0009966 225 0.017
regulation of signaling GO:0023051 235 0.017
erk1 and erk2 cascade GO:0070371 4 0.017
negative regulation of cellular process GO:0048523 283 0.017
positive regulation of jnk cascade GO:0046330 3 0.017
endosomal transport GO:0016197 2 0.017
response to hexose GO:0009746 3 0.017
peptidyl lysine acetylation GO:0018394 2 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
regulation of protein catabolic process GO:0042176 1 0.017
somatic muscle development GO:0007525 4 0.017
cellular response to organic substance GO:0071310 105 0.017
mitochondrion organization GO:0007005 4 0.017
sensory organ development GO:0007423 393 0.016
regionalization GO:0003002 274 0.016
myeloid cell differentiation GO:0030099 86 0.016
heart development GO:0007507 313 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
growth GO:0040007 174 0.016
response to organic substance GO:0010033 153 0.016
transport GO:0006810 220 0.016
gene expression GO:0010467 252 0.016
transmembrane transport GO:0055085 120 0.016
protein localization to plasma membrane GO:0072659 1 0.016
response to glucocorticoid GO:0051384 1 0.016
regulation of primary metabolic process GO:0080090 311 0.016
nucleobase containing compound metabolic process GO:0006139 274 0.016
cell proliferation GO:0008283 80 0.016
regulation of dna recombination GO:0000018 2 0.016
regulation of jak stat cascade GO:0046425 3 0.016
chordate embryonic development GO:0043009 271 0.016
regulation of macromolecule metabolic process GO:0060255 317 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
response to monosaccharide GO:0034284 3 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
cellular carbohydrate metabolic process GO:0044262 4 0.016
regulation of transcription dna templated GO:0006355 213 0.016
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.015
cellular protein catabolic process GO:0044257 4 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
spermatid development GO:0007286 2 0.015
ion transmembrane transport GO:0034220 91 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
positive regulation of response to stimulus GO:0048584 80 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
response to nutrient GO:0007584 3 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
response to alkaloid GO:0043279 2 0.015
regulation of organ growth GO:0046620 3 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
embryonic hemopoiesis GO:0035162 53 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
positive regulation of inflammatory response GO:0050729 1 0.015
pericardium morphogenesis GO:0003344 1 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
cellular protein metabolic process GO:0044267 129 0.015
response to uv GO:0009411 3 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.015
regulation of dna replication GO:0006275 3 0.015
determination of bilateral symmetry GO:0009855 204 0.015
negative regulation of defense response GO:0031348 2 0.015
regulation of cell shape GO:0008360 1 0.014
specification of symmetry GO:0009799 204 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
response to glucose GO:0009749 3 0.014
germ line stem cell maintenance GO:0030718 2 0.014
regulation of metal ion transport GO:0010959 4 0.014
negative regulation of biological process GO:0048519 304 0.014
single organism organelle organization GO:1902589 199 0.014
ameboidal type cell migration GO:0001667 143 0.014
activation of mapk activity GO:0000187 3 0.014
regulation of protein complex assembly GO:0043254 3 0.014
localization of cell GO:0051674 244 0.014
organism emergence from protective structure GO:0071684 4 0.014
positive regulation of translation GO:0045727 1 0.014
protein activation cascade GO:0072376 6 0.014
somatic cell dna recombination GO:0016444 1 0.014
positive regulation of catabolic process GO:0009896 4 0.014
leukocyte mediated cytotoxicity GO:0001909 1 0.014
fatty acid transport GO:0015908 1 0.014
positive regulation of cellular process GO:0048522 201 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
guanosine containing compound metabolic process GO:1901068 4 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
positive regulation of gliogenesis GO:0014015 2 0.014
regulation of blood vessel size GO:0050880 2 0.014
central nervous system development GO:0007417 387 0.014
superoxide metabolic process GO:0006801 2 0.014
single organism localization GO:1902578 225 0.013
immunoglobulin production GO:0002377 1 0.013
positive regulation of stem cell proliferation GO:2000648 1 0.013
organelle organization GO:0006996 227 0.013
regulation of leukocyte mediated immunity GO:0002703 1 0.013
macroautophagy GO:0016236 1 0.013
cellular response to starvation GO:0009267 1 0.013
multicellular organismal macromolecule metabolic process GO:0044259 2 0.013
regulation of blood pressure GO:0008217 1 0.013
developmental growth GO:0048589 166 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
cell morphogenesis GO:0000902 289 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.013
regulation of response to nutrient levels GO:0032107 1 0.013
somatic stem cell maintenance GO:0035019 1 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
cellular component movement GO:0006928 335 0.013
regulation of dna templated transcription in response to stress GO:0043620 0 0.013
regulation of response to extracellular stimulus GO:0032104 1 0.013
cell killing GO:0001906 2 0.013
brain development GO:0007420 293 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
positive regulation of cell killing GO:0031343 2 0.013
cellular component disassembly GO:0022411 1 0.013
defense response GO:0006952 47 0.013
cellular component morphogenesis GO:0032989 336 0.013
wound healing GO:0042060 90 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.013
hatching GO:0035188 4 0.012
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.012
zymogen activation GO:0031638 3 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
sensory perception of chemical stimulus GO:0007606 3 0.012
cell death GO:0008219 121 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
cell migration involved in gastrulation GO:0042074 79 0.012
regulation of muscle contraction GO:0006937 3 0.012
negative regulation of signal transduction GO:0009968 94 0.012
response to organic cyclic compound GO:0014070 51 0.012
regulation of lipid transport GO:0032368 4 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
establishment of endothelial barrier GO:0061028 3 0.012
gtp catabolic process GO:0006184 2 0.012
myeloid cell homeostasis GO:0002262 56 0.012
collagen metabolic process GO:0032963 2 0.012
meiotic cell cycle process GO:1903046 3 0.012
liver development GO:0001889 96 0.012
regulation of cytokine biosynthetic process GO:0042035 1 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
cell projection organization GO:0030030 284 0.012
regulation of reproductive process GO:2000241 4 0.012
glucose homeostasis GO:0042593 1 0.012
long chain fatty acid metabolic process GO:0001676 1 0.012
erythrocyte homeostasis GO:0034101 55 0.012
determination of dorsal ventral asymmetry GO:0048262 34 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.012
cell substrate adhesion GO:0031589 4 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
regulation of cell death GO:0010941 103 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
regulation of sodium ion transport GO:0002028 2 0.012
hepaticobiliary system development GO:0061008 98 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
renal tubule morphogenesis GO:0061333 1 0.012
system process GO:0003008 185 0.012
cellular response to reactive oxygen species GO:0034614 2 0.012
establishment of protein localization to plasma membrane GO:0090002 1 0.012
nuclear export GO:0051168 1 0.012
interspecies interaction between organisms GO:0044419 4 0.012
homeostasis of number of cells GO:0048872 62 0.012
regulation of immune system process GO:0002682 34 0.012
regulation of photoreceptor cell differentiation GO:0046532 2 0.012
telomere maintenance GO:0000723 1 0.012
viral process GO:0016032 1 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.011
actin filament based process GO:0030029 64 0.011
protein targeting to membrane GO:0006612 1 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
adherens junction organization GO:0034332 4 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
telomere organization GO:0032200 1 0.011
compound eye development GO:0048749 2 0.011
atp catabolic process GO:0006200 4 0.011
head development GO:0060322 303 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
embryonic organ morphogenesis GO:0048562 274 0.011
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
regulation of response to cytokine stimulus GO:0060759 3 0.011
regulation of programmed cell death GO:0043067 101 0.011
er nucleus signaling pathway GO:0006984 2 0.011
cell cell recognition GO:0009988 1 0.011
programmed cell death GO:0012501 119 0.011
positive regulation of leukocyte differentiation GO:1902107 1 0.011
mesenchymal cell proliferation GO:0010463 1 0.011
regulation of circadian rhythm GO:0042752 4 0.011
regulation of transporter activity GO:0032409 2 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
neuron neuron synaptic transmission GO:0007270 1 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
phagocytosis engulfment GO:0006911 1 0.011
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.011
glucose import GO:0046323 2 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
response to hydrogen peroxide GO:0042542 3 0.011
regulation of cell killing GO:0031341 2 0.011
adult behavior GO:0030534 2 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
regulation of apoptotic process GO:0042981 98 0.011
cell substrate junction assembly GO:0007044 2 0.011
regulation of localization GO:0032879 104 0.011
regulation of protein metabolic process GO:0051246 56 0.011
negative regulation of protein transport GO:0051224 3 0.011
spermatid differentiation GO:0048515 2 0.011
proepicardium development GO:0003342 4 0.011
antimicrobial humoral response GO:0019730 2 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
locomotion GO:0040011 313 0.011
sensory organ morphogenesis GO:0090596 200 0.011
homeostatic process GO:0042592 142 0.011
notochord development GO:0030903 54 0.011
cellular amide metabolic process GO:0043603 4 0.010
proteasomal protein catabolic process GO:0010498 2 0.010
cellular response to unfolded protein GO:0034620 2 0.010
regulation of gtpase activity GO:0043087 2 0.010
photoreceptor cell fate commitment GO:0046552 1 0.010
regeneration GO:0031099 91 0.010
positive regulation of multi organism process GO:0043902 3 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
response to oxygen containing compound GO:1901700 55 0.010
dna templated transcription elongation GO:0006354 3 0.010
protein modification process GO:0036211 100 0.010
regulation of cell substrate adhesion GO:0010810 1 0.010
negative regulation of leukocyte differentiation GO:1902106 1 0.010
regulation of intracellular ph GO:0051453 1 0.010
cell aging GO:0007569 2 0.010
energy reserve metabolic process GO:0006112 2 0.010
toll like receptor signaling pathway GO:0002224 4 0.010
positive regulation of neuron apoptotic process GO:0043525 1 0.010
regulation of wound healing GO:0061041 2 0.010
synaptic growth at neuromuscular junction GO:0051124 2 0.010
negative regulation of secretion GO:0051048 2 0.010
regulation of mesenchymal cell proliferation GO:0010464 1 0.010
rna localization GO:0006403 4 0.010
regulation of cellular ph GO:0030641 1 0.010
nitric oxide biosynthetic process GO:0006809 2 0.010
reactive oxygen species biosynthetic process GO:1903409 1 0.010
regulation of growth rate GO:0040009 1 0.010
ovulation cycle process GO:0022602 2 0.010

zgc:153941 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.020
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
disease of metabolism DOID:0014667 0 0.015
musculoskeletal system disease DOID:17 0 0.013
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
organ system cancer DOID:0050686 0 0.010