Danio rerio

21 known processes

snrnp70

small nuclear ribonucleoprotein 70 (U1)

(Aliases: MGC136450,zgc:136450,snrp70,wu:fc20b04)

snrnp70 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of mrna splicing via spliceosome GO:0048024 3 0.977
mrna splicing via spliceosome GO:0000398 10 0.957
alternative mrna splicing via spliceosome GO:0000380 1 0.950
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.942
rna splicing GO:0008380 16 0.937
mrna processing GO:0006397 14 0.894
regulation of mrna processing GO:0050684 3 0.886
hematopoietic or lymphoid organ development GO:0048534 191 0.739
rna splicing via transesterification reactions GO:0000375 10 0.717
larval development GO:0002164 2 0.693
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.687
mrna metabolic process GO:0016071 20 0.667
negative regulation of rna splicing GO:0033119 1 0.567
immune system development GO:0002520 191 0.513
meiotic nuclear division GO:0007126 4 0.491
regulation of cellular metabolic process GO:0031323 320 0.489
hemopoiesis GO:0030097 183 0.428
rna processing GO:0006396 25 0.413
negative regulation of cellular process GO:0048523 283 0.397
cell cycle GO:0007049 93 0.385
regulation of meiotic cell cycle GO:0051445 1 0.377
immune system process GO:0002376 241 0.377
regulation of rna splicing GO:0043484 8 0.369
locomotion GO:0040011 313 0.364
embryo development ending in birth or egg hatching GO:0009792 271 0.357
gene expression GO:0010467 252 0.323
regulation of metabolic process GO:0019222 359 0.307
organic cyclic compound metabolic process GO:1901360 301 0.307
nitrogen compound metabolic process GO:0006807 319 0.294
regulation of biological quality GO:0065008 263 0.287
cellular component assembly GO:0022607 170 0.258
regulation of primary metabolic process GO:0080090 311 0.242
establishment of localization GO:0051234 244 0.235
regulation of gene expression GO:0010468 265 0.235
single organism organelle organization GO:1902589 199 0.222
transport GO:0006810 220 0.216
rna metabolic process GO:0016070 219 0.215
stem cell differentiation GO:0048863 117 0.194
aging GO:0007568 2 0.187
hematopoietic progenitor cell differentiation GO:0002244 23 0.184
cellular macromolecule metabolic process GO:0044260 391 0.171
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.164
regulation of mrna metabolic process GO:1903311 6 0.159
spliceosomal complex assembly GO:0000245 1 0.156
nucleic acid metabolic process GO:0090304 244 0.155
cell death GO:0008219 121 0.151
regulation of developmental process GO:0050793 247 0.146
regulation of macromolecule metabolic process GO:0060255 317 0.143
heterocycle metabolic process GO:0046483 290 0.143
nucleocytoplasmic transport GO:0006913 4 0.141
positive regulation of biological process GO:0048518 253 0.141
macromolecular complex assembly GO:0065003 35 0.138
cellular component biogenesis GO:0044085 178 0.133
cell migration GO:0016477 237 0.130
developmental process involved in reproduction GO:0003006 27 0.127
localization of cell GO:0051674 244 0.126
regulation of multicellular organism growth GO:0040014 4 0.122
cell motility GO:0048870 244 0.115
hematopoietic stem cell differentiation GO:0060218 20 0.111
cellular nitrogen compound metabolic process GO:0034641 290 0.111
organelle organization GO:0006996 227 0.111
cellular aromatic compound metabolic process GO:0006725 295 0.109
negative regulation of biological process GO:0048519 304 0.107
regulation of multicellular organismal process GO:0051239 277 0.107
erythrocyte homeostasis GO:0034101 55 0.101
maintenance of location GO:0051235 4 0.101
intracellular estrogen receptor signaling pathway GO:0030520 3 0.100
regulation of multicellular organismal development GO:2000026 223 0.100
multicellular organismal reproductive process GO:0048609 35 0.098
nuclear transport GO:0051169 4 0.097
signal transduction GO:0007165 455 0.092
growth GO:0040007 174 0.091
translational initiation GO:0006413 3 0.084
cellular component movement GO:0006928 335 0.083
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.082
nucleic acid transport GO:0050657 2 0.081
multicellular organism growth GO:0035264 4 0.081
positive regulation of metabolic process GO:0009893 108 0.080
cellular macromolecular complex assembly GO:0034622 24 0.080
response to stress GO:0006950 263 0.078
regulation of rna metabolic process GO:0051252 224 0.078
organic cyclic compound biosynthetic process GO:1901362 223 0.078
regulation of nitrogen compound metabolic process GO:0051171 251 0.078
negative regulation of mrna metabolic process GO:1903312 3 0.077
regulation of synapse assembly GO:0051963 3 0.075
rna stabilization GO:0043489 4 0.074
establishment of protein localization to organelle GO:0072594 4 0.068
stem cell maintenance GO:0019827 4 0.068
viral process GO:0016032 1 0.067
negative regulation of gene expression GO:0010629 65 0.067
rna export from nucleus GO:0006405 1 0.065
regulation of cell cycle GO:0051726 52 0.065
negative regulation of metabolic process GO:0009892 86 0.064
regulation of cell proliferation GO:0042127 37 0.064
epithelial cell differentiation GO:0030855 116 0.063
nuclear import GO:0051170 3 0.063
lipid storage GO:0019915 1 0.061
regulation of cell death GO:0010941 103 0.061
macromolecule biosynthetic process GO:0009059 227 0.060
ribonucleoprotein complex assembly GO:0022618 5 0.059
macromolecular complex subunit organization GO:0043933 74 0.059
aromatic compound biosynthetic process GO:0019438 217 0.059
positive regulation of cell cycle GO:0045787 3 0.058
regulation of response to stimulus GO:0048583 269 0.058
regulation of cell communication GO:0010646 232 0.057
neuron development GO:0048666 262 0.057
regulation of establishment of protein localization GO:0070201 4 0.057
mitotic cell cycle GO:0000278 64 0.056
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.055
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.055
positive regulation of cellular component biogenesis GO:0044089 3 0.055
negative regulation of cellular metabolic process GO:0031324 77 0.055
regulation of protein import into nucleus GO:0042306 2 0.054
positive regulation of transport GO:0051050 2 0.054
heterocycle biosynthetic process GO:0018130 215 0.053
reproductive process GO:0022414 40 0.053
positive regulation of synapse assembly GO:0051965 1 0.052
biosynthetic process GO:0009058 294 0.052
regulation of cytokine production GO:0001817 3 0.052
nucleic acid templated transcription GO:0097659 181 0.051
cellular biosynthetic process GO:0044249 286 0.051
nuclear export GO:0051168 1 0.051
protein metabolic process GO:0019538 183 0.051
gamete generation GO:0007276 33 0.050
mitotic cell cycle process GO:1903047 48 0.050
multicellular organism reproduction GO:0032504 35 0.049
macromolecule localization GO:0033036 54 0.048
negative regulation of mrna processing GO:0050686 1 0.048
single organism nuclear import GO:1902593 3 0.048
erythrocyte differentiation GO:0030218 54 0.047
protein import into nucleus GO:0006606 3 0.047
oocyte anterior posterior axis specification GO:0007314 4 0.046
regulation of cytoplasmic transport GO:1903649 4 0.045
negative regulation of mrna splicing via spliceosome GO:0048025 1 0.045
protein localization to nucleus GO:0034504 3 0.045
cellular component disassembly GO:0022411 1 0.044
negative regulation of macromolecule metabolic process GO:0010605 76 0.044
regulation of cellular component organization GO:0051128 86 0.044
mitotic nuclear division GO:0007067 18 0.043
sexual reproduction GO:0019953 36 0.043
protein targeting to nucleus GO:0044744 3 0.042
rna biosynthetic process GO:0032774 181 0.041
myeloid cell differentiation GO:0030099 86 0.041
3 utr mediated mrna stabilization GO:0070935 3 0.041
cellular protein catabolic process GO:0044257 4 0.041
single organism localization GO:1902578 225 0.040
circulatory system process GO:0003013 87 0.040
neuron differentiation GO:0030182 353 0.040
single organism metabolic process GO:0044710 217 0.039
regulation of signal transduction GO:0009966 225 0.038
nuclear division GO:0000280 23 0.038
axon development GO:0061564 166 0.038
cellular macromolecule biosynthetic process GO:0034645 224 0.037
cell proliferation GO:0008283 80 0.037
amine metabolic process GO:0009308 2 0.037
regulation of growth rate GO:0040009 1 0.037
multi organism cellular process GO:0044764 2 0.037
dna templated transcription elongation GO:0006354 3 0.037
reproduction GO:0000003 40 0.037
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.036
germ cell development GO:0007281 22 0.036
regulation of cellular biosynthetic process GO:0031326 245 0.036
organelle assembly GO:0070925 110 0.036
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.036
cell cycle process GO:0022402 53 0.035
synaptic growth at neuromuscular junction GO:0051124 2 0.035
regulation of protein targeting GO:1903533 2 0.035
rna transport GO:0050658 2 0.034
regulation of transcription dna templated GO:0006355 213 0.034
angiogenesis GO:0001525 158 0.033
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.033
regionalization GO:0003002 274 0.033
interspecies interaction between organisms GO:0044419 4 0.033
regulation of cellular ketone metabolic process GO:0010565 7 0.032
regulation of erk1 and erk2 cascade GO:0070372 4 0.032
segmentation GO:0035282 97 0.032
regulation of localization GO:0032879 104 0.032
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.031
mrna stabilization GO:0048255 4 0.031
nucleobase containing compound metabolic process GO:0006139 274 0.031
development of primary sexual characteristics GO:0045137 5 0.030
positive regulation of multicellular organismal process GO:0051240 52 0.030
positive regulation of leukocyte differentiation GO:1902107 1 0.030
positive regulation of macromolecule metabolic process GO:0010604 93 0.030
regulation of nucleic acid templated transcription GO:1903506 213 0.030
transcription dna templated GO:0006351 181 0.029
cellular localization GO:0051641 97 0.029
protein complex subunit organization GO:0071822 46 0.029
meiotic chromosome segregation GO:0045132 3 0.029
regulation of protein complex assembly GO:0043254 3 0.028
response to external biotic stimulus GO:0043207 97 0.028
homeostatic process GO:0042592 142 0.028
meiotic cell cycle process GO:1903046 3 0.028
dna catabolic process GO:0006308 1 0.027
cytoskeleton organization GO:0007010 96 0.027
regulation of mitotic cell cycle embryonic GO:0009794 2 0.027
intracellular transport GO:0046907 32 0.027
heart contraction GO:0060047 71 0.027
organic substance biosynthetic process GO:1901576 289 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.027
death GO:0016265 121 0.027
neuron projection extension GO:1990138 45 0.027
establishment of rna localization GO:0051236 3 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.026
regulation of cell migration GO:0030334 40 0.026
protein complex disassembly GO:0043241 1 0.026
regulation of nucleocytoplasmic transport GO:0046822 2 0.025
stem cell development GO:0048864 82 0.025
positive regulation of cellular process GO:0048522 201 0.025
multi organism process GO:0051704 134 0.025
cellular ketone metabolic process GO:0042180 11 0.025
response to chemical GO:0042221 320 0.025
i kappab kinase nf kappab signaling GO:0007249 4 0.024
cell projection organization GO:0030030 284 0.024
transcription from rna polymerase ii promoter GO:0006366 80 0.024
development of primary female sexual characteristics GO:0046545 4 0.024
neural crest cell differentiation GO:0014033 72 0.023
regulation of signaling GO:0023051 235 0.023
positive regulation of dna templated transcription elongation GO:0032786 1 0.023
system process GO:0003008 185 0.023
mesenchymal cell differentiation GO:0048762 87 0.023
regulation of macromolecule biosynthetic process GO:0010556 225 0.023
chromosome organization involved in meiosis GO:0070192 1 0.023
response to drug GO:0042493 3 0.023
anterior posterior pattern specification GO:0009952 152 0.023
axon guidance GO:0007411 86 0.022
positive regulation of myeloid cell differentiation GO:0045639 2 0.022
gland development GO:0048732 143 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
cellular protein metabolic process GO:0044267 129 0.022
modification dependent macromolecule catabolic process GO:0043632 3 0.022
female sex differentiation GO:0046660 4 0.022
response to uv GO:0009411 3 0.022
carboxylic acid metabolic process GO:0019752 22 0.022
negative regulation of chromosome organization GO:2001251 1 0.021
chromosome organization GO:0051276 31 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
programmed cell death GO:0012501 119 0.021
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.021
central nervous system development GO:0007417 387 0.021
regulation of organelle organization GO:0033043 29 0.021
modification of morphology or physiology of other organism GO:0035821 4 0.021
adult behavior GO:0030534 2 0.021
negative regulation of translation GO:0017148 1 0.021
positive regulation of gene expression GO:0010628 71 0.021
homeostasis of number of cells GO:0048872 62 0.021
dorsal ventral pattern formation GO:0009953 125 0.021
maternal determination of anterior posterior axis embryo GO:0008358 4 0.020
regulation of dna templated transcription elongation GO:0032784 3 0.020
positive regulation of cellular biosynthetic process GO:0031328 68 0.020
pole plasm assembly GO:0007315 4 0.020
myeloid cell homeostasis GO:0002262 56 0.020
multi organism reproductive process GO:0044703 36 0.019
cellular response to external stimulus GO:0071496 2 0.019
negative regulation of cellular biosynthetic process GO:0031327 55 0.019
digestive system development GO:0055123 289 0.019
regulation of cellular protein metabolic process GO:0032268 52 0.019
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.019
organelle fission GO:0048285 23 0.019
embryonic pattern specification GO:0009880 44 0.019
nucleobase containing compound transport GO:0015931 2 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.019
protein import GO:0017038 3 0.019
posttranscriptional regulation of gene expression GO:0010608 14 0.019
heart process GO:0003015 71 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
female gonad development GO:0008585 4 0.018
negative regulation of biosynthetic process GO:0009890 55 0.018
cellular response to dsrna GO:0071359 1 0.018
single organism reproductive process GO:0044702 40 0.018
regulation of biosynthetic process GO:0009889 250 0.018
single organism transport GO:0044765 206 0.018
positive regulation of developmental process GO:0051094 50 0.017
muscle cell development GO:0055001 115 0.017
axis specification GO:0009798 43 0.017
organism emergence from protective structure GO:0071684 4 0.017
epidermal cell differentiation GO:0009913 36 0.017
response to biotic stimulus GO:0009607 97 0.017
heart development GO:0007507 313 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
female gamete generation GO:0007292 14 0.017
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 9 0.017
regulation of protein complex disassembly GO:0043244 1 0.017
regulation of mrna stability GO:0043488 4 0.017
regulation of protein metabolic process GO:0051246 56 0.017
sensory organ development GO:0007423 393 0.017
mesenchyme development GO:0060485 127 0.016
organic substance transport GO:0071702 58 0.016
intracellular signal transduction GO:0035556 85 0.016
vasculature development GO:0001944 278 0.016
protein acetylation GO:0006473 2 0.016
negative regulation of rna metabolic process GO:0051253 48 0.016
macromolecular complex disassembly GO:0032984 1 0.016
cell aging GO:0007569 2 0.016
intracellular mrna localization GO:0008298 1 0.016
digestive tract morphogenesis GO:0048546 231 0.016
organic acid metabolic process GO:0006082 31 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
positive regulation of rna metabolic process GO:0051254 59 0.016
regulation of nuclear division GO:0051783 9 0.016
cellular amine metabolic process GO:0044106 2 0.016
negative regulation of rna biosynthetic process GO:1902679 45 0.016
protein stabilization GO:0050821 2 0.016
mitotic dna integrity checkpoint GO:0044774 4 0.015
response to organic substance GO:0010033 153 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
spermatid differentiation GO:0048515 2 0.015
positive regulation of chromatin modification GO:1903310 1 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
positive regulation of rna biosynthetic process GO:1902680 57 0.015
microtubule cytoskeleton organization GO:0000226 33 0.015
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.015
regulation of translational initiation GO:0006446 1 0.015
positive regulation of nervous system development GO:0051962 25 0.015
regulation of protein catabolic process GO:0042176 1 0.015
regulation of glucose transport GO:0010827 1 0.015
cellular macromolecule catabolic process GO:0044265 12 0.014
mitotic g2 m transition checkpoint GO:0044818 3 0.014
oxoacid metabolic process GO:0043436 31 0.014
pericardium morphogenesis GO:0003344 1 0.014
translation GO:0006412 5 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.014
mitotic g2 dna damage checkpoint GO:0007095 3 0.014
fertilization GO:0009566 3 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
rna localization GO:0006403 4 0.014
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.014
regulation of growth GO:0040008 42 0.014
regulation of gene expression epigenetic GO:0040029 11 0.014
positive regulation of chromosome organization GO:2001252 1 0.014
embryonic organ development GO:0048568 381 0.014
blood circulation GO:0008015 87 0.014
keratinocyte differentiation GO:0030216 0 0.013
muscle cell differentiation GO:0042692 139 0.013
apoptotic process GO:0006915 116 0.013
positive regulation of mrna metabolic process GO:1903313 2 0.013
regulation of programmed cell death GO:0043067 101 0.013
positive regulation of translation GO:0045727 1 0.013
protein polymerization GO:0051258 4 0.013
locomotory behavior GO:0007626 34 0.013
regulation of organ growth GO:0046620 3 0.013
regulation of protein transport GO:0051223 3 0.013
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.013
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.013
regulation of cell cycle process GO:0010564 20 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
positive regulation of cytokine production GO:0001819 2 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
centrosome organization GO:0051297 1 0.012
negative regulation of cell differentiation GO:0045596 46 0.012
response to wounding GO:0009611 116 0.012
negative regulation of mitosis GO:0045839 3 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
negative regulation of multicellular organismal process GO:0051241 69 0.012
cell morphogenesis GO:0000902 289 0.012
cytoplasm organization GO:0007028 4 0.012
ribonucleoprotein complex biogenesis GO:0022613 13 0.012
blood vessel morphogenesis GO:0048514 216 0.012
regulation of cell activation GO:0050865 1 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
response to abiotic stimulus GO:0009628 122 0.012
developmental growth GO:0048589 166 0.012
blood vessel development GO:0001568 246 0.011
sex differentiation GO:0007548 5 0.011
regulation of reproductive process GO:2000241 4 0.011
meiotic spindle organization GO:0000212 1 0.011
macromolecule modification GO:0043412 111 0.011
response to bacterium GO:0009617 58 0.011
endocytosis GO:0006897 16 0.011
regulation of cell differentiation GO:0045595 142 0.011
single organism intracellular transport GO:1902582 25 0.011
muscle contraction GO:0006936 18 0.011
stem cell proliferation GO:0072089 4 0.011
embryonic digestive tract morphogenesis GO:0048557 3 0.011
g2 dna damage checkpoint GO:0031572 3 0.011
negative regulation of developmental process GO:0051093 65 0.011
negative regulation of multi organism process GO:0043901 3 0.011
negative regulation of kinase activity GO:0033673 4 0.011
mrna export from nucleus GO:0006406 1 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
camera type eye development GO:0043010 222 0.011
negative regulation of cellular component organization GO:0051129 16 0.011
leukocyte differentiation GO:0002521 25 0.011
negative regulation of nuclear division GO:0051784 3 0.011
hepaticobiliary system development GO:0061008 98 0.011
gastrulation GO:0007369 208 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
regulation of synapse organization GO:0050807 3 0.011
neuron projection morphogenesis GO:0048812 161 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010
regulation of histone methylation GO:0031060 3 0.010
regulation of epidermis development GO:0045682 2 0.010
regulation of oxidative stress induced cell death GO:1903201 2 0.010
dsrna fragmentation GO:0031050 1 0.010
central nervous system neuron differentiation GO:0021953 74 0.010
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010
positive regulation of cell activation GO:0050867 1 0.010

snrnp70 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
motor neuron disease DOID:231 0 0.264
central nervous system disease DOID:331 0 0.264
amyotrophic lateral sclerosis DOID:332 0 0.264
disease of anatomical entity DOID:7 0 0.264
neurodegenerative disease DOID:1289 0 0.264
nervous system disease DOID:863 0 0.264
musculoskeletal system disease DOID:17 0 0.035
muscular disease DOID:0080000 0 0.025
myopathy DOID:423 0 0.020
muscle tissue disease DOID:66 0 0.020
muscular dystrophy DOID:9884 0 0.011
limb girdle muscular dystrophy DOID:11724 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010