Danio rerio

48 known processes

dner

delta/notch-like EGF repeat containing

dner biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
morphogenesis of an epithelium GO:0002009 333 0.082
ear development GO:0043583 127 0.078
sensory organ development GO:0007423 393 0.076
organic acid metabolic process GO:0006082 31 0.073
immune system development GO:0002520 191 0.069
compound eye development GO:0048749 2 0.056
oxoacid metabolic process GO:0043436 31 0.056
regionalization GO:0003002 274 0.053
cognition GO:0050890 1 0.052
brain development GO:0007420 293 0.049
system process GO:0003008 185 0.046
eye development GO:0001654 277 0.045
regulation of developmental process GO:0050793 247 0.045
head development GO:0060322 303 0.044
vasculature development GO:0001944 278 0.044
blood vessel development GO:0001568 246 0.043
adult behavior GO:0030534 2 0.043
larval development GO:0002164 2 0.041
hemopoiesis GO:0030097 183 0.041
aging GO:0007568 2 0.039
amine metabolic process GO:0009308 2 0.038
hematopoietic or lymphoid organ development GO:0048534 191 0.038
cellular amine metabolic process GO:0044106 2 0.037
regulation of biological quality GO:0065008 263 0.037
carboxylic acid metabolic process GO:0019752 22 0.036
signal transduction GO:0007165 455 0.036
sensory organ morphogenesis GO:0090596 200 0.036
regulation of multicellular organism growth GO:0040014 4 0.035
regulation of cellular amine metabolic process GO:0033238 0 0.035
multicellular organism growth GO:0035264 4 0.034
regulation of signal transduction GO:0009966 225 0.034
embryonic organ development GO:0048568 381 0.033
tube morphogenesis GO:0035239 349 0.032
stem cell proliferation GO:0072089 4 0.032
immune system process GO:0002376 241 0.031
angiogenesis GO:0001525 158 0.030
cellular macromolecule metabolic process GO:0044260 391 0.030
inner ear development GO:0048839 126 0.030
aromatic compound biosynthetic process GO:0019438 217 0.029
hormone transport GO:0009914 2 0.029
blood vessel morphogenesis GO:0048514 216 0.029
maintenance of location GO:0051235 4 0.028
response to alkaloid GO:0043279 2 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.027
organonitrogen compound metabolic process GO:1901564 74 0.027
stem cell maintenance GO:0019827 4 0.026
neuron differentiation GO:0030182 353 0.026
embryonic organ morphogenesis GO:0048562 274 0.025
nucleic acid metabolic process GO:0090304 244 0.025
regulation of biosynthetic process GO:0009889 250 0.025
biosynthetic process GO:0009058 294 0.025
regulation of macromolecule biosynthetic process GO:0010556 225 0.025
retina development in camera type eye GO:0060041 146 0.024
digestive tract morphogenesis GO:0048546 231 0.024
cell morphogenesis GO:0000902 289 0.024
protein localization to nucleus GO:0034504 3 0.024
heterocycle biosynthetic process GO:0018130 215 0.024
positive regulation of transport GO:0051050 2 0.023
regulation of multicellular organismal development GO:2000026 223 0.023
central nervous system development GO:0007417 387 0.023
phagocytosis GO:0006909 3 0.023
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
regulation of cellular biosynthetic process GO:0031326 245 0.023
cellular amino acid metabolic process GO:0006520 7 0.023
organic cyclic compound biosynthetic process GO:1901362 223 0.022
cellular biosynthetic process GO:0044249 286 0.022
regulation of neural precursor cell proliferation GO:2000177 3 0.022
gene expression GO:0010467 252 0.022
rna metabolic process GO:0016070 219 0.022
camera type eye development GO:0043010 222 0.022
homeostatic process GO:0042592 142 0.022
digestive system development GO:0055123 289 0.022
cellular component morphogenesis GO:0032989 336 0.021
neuroblast proliferation GO:0007405 2 0.021
regulation of stem cell proliferation GO:0072091 2 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
positive regulation of cell cycle GO:0045787 3 0.021
chemosensory behavior GO:0007635 1 0.021
generation of neurons GO:0048699 385 0.020
locomotion GO:0040011 313 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
nucleobase containing compound biosynthetic process GO:0034654 205 0.020
nucleic acid templated transcription GO:0097659 181 0.020
response to drug GO:0042493 3 0.020
muscle cell development GO:0055001 115 0.020
regulation of blood pressure GO:0008217 1 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
regulation of cell communication GO:0010646 232 0.019
macromolecule biosynthetic process GO:0009059 227 0.019
heterocycle metabolic process GO:0046483 290 0.019
regulation of metal ion transport GO:0010959 4 0.019
neuron neuron synaptic transmission GO:0007270 1 0.019
renal system development GO:0072001 94 0.018
nuclear import GO:0051170 3 0.018
response to nutrient GO:0007584 3 0.018
response to external stimulus GO:0009605 264 0.018
hormone secretion GO:0046879 2 0.018
response to chemical GO:0042221 320 0.018
negative regulation of cellular process GO:0048523 283 0.018
rna biosynthetic process GO:0032774 181 0.018
cell projection morphogenesis GO:0048858 244 0.018
regulation of cell activation GO:0050865 1 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
ear morphogenesis GO:0042471 64 0.018
response to stress GO:0006950 263 0.017
synaptic vesicle transport GO:0048489 1 0.017
axon ensheathment in central nervous system GO:0032291 2 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
skeletal muscle organ development GO:0060538 78 0.017
regulation of tube size GO:0035150 2 0.017
regulation of primary metabolic process GO:0080090 311 0.017
nitrogen compound metabolic process GO:0006807 319 0.017
cell part morphogenesis GO:0032990 246 0.017
fin development GO:0033333 77 0.017
regulation of macromolecule metabolic process GO:0060255 317 0.017
specification of symmetry GO:0009799 204 0.017
organic cyclic compound metabolic process GO:1901360 301 0.017
response to hexose GO:0009746 3 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
small molecule metabolic process GO:0044281 77 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
regulation of rna metabolic process GO:0051252 224 0.016
central nervous system myelination GO:0022010 2 0.016
regulation of transcription dna templated GO:0006355 213 0.016
regulation of reproductive process GO:2000241 4 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.016
regulation of response to stimulus GO:0048583 269 0.016
peptidyl serine modification GO:0018209 2 0.016
muscle fiber development GO:0048747 52 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
neuron fate determination GO:0048664 2 0.016
response to carbohydrate GO:0009743 3 0.016
nucleobase containing compound metabolic process GO:0006139 274 0.015
central nervous system neuron differentiation GO:0021953 74 0.015
sensory perception of chemical stimulus GO:0007606 3 0.015
female sex differentiation GO:0046660 4 0.015
neuron development GO:0048666 262 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
regulation of protein complex assembly GO:0043254 3 0.015
regulation of systemic arterial blood pressure GO:0003073 1 0.015
skin development GO:0043588 54 0.015
organic substance biosynthetic process GO:1901576 289 0.015
response to amine GO:0014075 1 0.015
hindbrain development GO:0030902 91 0.015
carbohydrate homeostasis GO:0033500 1 0.015
negative regulation of kinase activity GO:0033673 4 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
transcription dna templated GO:0006351 181 0.015
otolith development GO:0048840 32 0.015
muscle structure development GO:0061061 196 0.015
positive regulation of catabolic process GO:0009896 4 0.015
cranial nerve development GO:0021545 42 0.015
cellular aromatic compound metabolic process GO:0006725 295 0.015
cell surface receptor signaling pathway GO:0007166 325 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
regulation of signaling GO:0023051 235 0.015
behavior GO:0007610 74 0.015
positive regulation of biological process GO:0048518 253 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
response to amphetamine GO:0001975 1 0.014
cellular protein catabolic process GO:0044257 4 0.014
cellular nitrogen compound metabolic process GO:0034641 290 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
nuclear transport GO:0051169 4 0.014
adherens junction organization GO:0034332 4 0.014
regulation of circadian rhythm GO:0042752 4 0.014
peptide transport GO:0015833 1 0.014
cellular response to light stimulus GO:0071482 4 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
lipid storage GO:0019915 1 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
female gonad development GO:0008585 4 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
regulation of synaptic plasticity GO:0048167 1 0.014
regulation of gene expression GO:0010468 265 0.014
response to abiotic stimulus GO:0009628 122 0.014
gtp catabolic process GO:0006184 2 0.014
establishment of localization GO:0051234 244 0.014
chemotaxis GO:0006935 104 0.013
segmentation GO:0035282 97 0.013
neurotransmitter secretion GO:0007269 2 0.013
single organism metabolic process GO:0044710 217 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
regulation of cellular metabolic process GO:0031323 320 0.013
sensory perception of pain GO:0019233 1 0.013
stem cell fate commitment GO:0048865 1 0.013
cellular amide metabolic process GO:0043603 4 0.013
regulation of apoptotic process GO:0042981 98 0.013
determination of left right symmetry GO:0007368 179 0.013
response to glucose GO:0009749 3 0.013
regulation of protein transport GO:0051223 3 0.013
response to radiation GO:0009314 51 0.013
eye morphogenesis GO:0048592 144 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
transcription from rna polymerase ii promoter GO:0006366 80 0.012
regulation of blood vessel size GO:0050880 2 0.012
peptide metabolic process GO:0006518 1 0.012
heart morphogenesis GO:0003007 156 0.012
cellular ketone metabolic process GO:0042180 11 0.012
synaptic vesicle localization GO:0097479 1 0.012
glucose homeostasis GO:0042593 1 0.012
mitochondrion organization GO:0007005 4 0.012
lymphocyte proliferation GO:0046651 1 0.012
regulation of programmed cell death GO:0043067 101 0.012
negative regulation of cell death GO:0060548 60 0.012
b cell activation GO:0042113 2 0.012
blood circulation GO:0008015 87 0.012
protein metabolic process GO:0019538 183 0.012
macromolecular complex disassembly GO:0032984 1 0.012
regulation of binding GO:0051098 3 0.012
cellular response to radiation GO:0071478 4 0.012
cellular component biogenesis GO:0044085 178 0.012
heart development GO:0007507 313 0.012
gastrulation GO:0007369 208 0.012
wnt signaling pathway GO:0016055 80 0.012
positive regulation of cell activation GO:0050867 1 0.012
olfactory lobe development GO:0021988 4 0.012
gland development GO:0048732 143 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
protein import GO:0017038 3 0.012
striated muscle cell differentiation GO:0051146 129 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
striated muscle cell development GO:0055002 108 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
cellular component assembly GO:0022607 170 0.011
regulation of protein catabolic process GO:0042176 1 0.011
regulation of metabolic process GO:0019222 359 0.011
nerve development GO:0021675 45 0.011
sympathetic nervous system development GO:0048485 3 0.011
cell projection organization GO:0030030 284 0.011
macromolecule modification GO:0043412 111 0.011
water homeostasis GO:0030104 4 0.011
epidermal cell fate specification GO:0009957 4 0.011
establishment of protein localization to organelle GO:0072594 4 0.011
regulation of hormone secretion GO:0046883 2 0.011
leukocyte proliferation GO:0070661 1 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
positive regulation of secretion GO:0051047 1 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
multicellular organismal response to stress GO:0033555 2 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
phagocytosis engulfment GO:0006911 1 0.011
regulation of mrna processing GO:0050684 3 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
positive regulation of cytokine production GO:0001819 2 0.011
positive regulation of blood circulation GO:1903524 2 0.011
positive regulation of signal transduction GO:0009967 56 0.011
response to light stimulus GO:0009416 46 0.011
axon development GO:0061564 166 0.011
skeletal system morphogenesis GO:0048705 102 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
myelin assembly GO:0032288 1 0.011
kidney development GO:0001822 92 0.010
negative regulation of biological process GO:0048519 304 0.010
meiotic cell cycle process GO:1903046 3 0.010
protein heterooligomerization GO:0051291 1 0.010
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.010
mechanoreceptor differentiation GO:0042490 37 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
regulation of synapse organization GO:0050807 3 0.010
determination of bilateral symmetry GO:0009855 204 0.010
membrane invagination GO:0010324 1 0.010
outflow tract morphogenesis GO:0003151 1 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
lipid catabolic process GO:0016042 4 0.010
protein complex biogenesis GO:0070271 30 0.010
auditory receptor cell fate determination GO:0042668 2 0.010
stem cell differentiation GO:0048863 117 0.010
modification dependent protein catabolic process GO:0019941 3 0.010
olfactory bulb development GO:0021772 4 0.010
circulatory system process GO:0003013 87 0.010
transport GO:0006810 220 0.010
muscle organ development GO:0007517 101 0.010

dner disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.019
disease of metabolism DOID:0014667 0 0.016
musculoskeletal system disease DOID:17 0 0.010