Danio rerio

44 known processes

ngfrl

nerve growth factor receptor (TNFR superfamily, member 16) like

ngfrl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
posterior lateral line system development GO:0048915 46 0.213
cell motility GO:0048870 244 0.208
lateral line system development GO:0048925 76 0.179
sensory organ development GO:0007423 393 0.164
sensory system development GO:0048880 76 0.145
cell migration GO:0016477 237 0.137
cellular component movement GO:0006928 335 0.119
generation of neurons GO:0048699 385 0.097
stem cell proliferation GO:0072089 4 0.085
lateral line development GO:0048882 66 0.083
central nervous system development GO:0007417 387 0.079
localization of cell GO:0051674 244 0.075
cellular macromolecule metabolic process GO:0044260 391 0.069
posterior lateral line development GO:0048916 38 0.063
head development GO:0060322 303 0.063
eye development GO:0001654 277 0.063
single fertilization GO:0007338 3 0.063
negative regulation of biological process GO:0048519 304 0.062
vasculature development GO:0001944 278 0.060
locomotion GO:0040011 313 0.057
nitrogen compound metabolic process GO:0006807 319 0.055
retina development in camera type eye GO:0060041 146 0.054
neurological system process GO:0050877 62 0.053
fertilization GO:0009566 3 0.052
regulation of nitrogen compound metabolic process GO:0051171 251 0.050
cellular nitrogen compound metabolic process GO:0034641 290 0.049
gtp catabolic process GO:0006184 2 0.049
brain development GO:0007420 293 0.048
neuromast development GO:0048884 46 0.047
skeletal system development GO:0001501 181 0.047
regulation of blood pressure GO:0008217 1 0.046
nuclear migration GO:0007097 3 0.046
guanosine containing compound catabolic process GO:1901069 2 0.045
single organism metabolic process GO:0044710 217 0.044
regulation of biological quality GO:0065008 263 0.044
neuron differentiation GO:0030182 353 0.043
positive regulation of transport GO:0051050 2 0.043
medulla oblongata development GO:0021550 4 0.043
embryonic organ morphogenesis GO:0048562 274 0.043
embryonic organ development GO:0048568 381 0.042
ameboidal type cell migration GO:0001667 143 0.042
cognition GO:0050890 1 0.042
response to external stimulus GO:0009605 264 0.041
regulation of oligodendrocyte differentiation GO:0048713 1 0.041
guanosine containing compound metabolic process GO:1901068 4 0.040
gtp metabolic process GO:0046039 4 0.039
response to chemical GO:0042221 320 0.038
gland development GO:0048732 143 0.038
regulation of cellular ketone metabolic process GO:0010565 7 0.038
establishment of localization GO:0051234 244 0.037
response to drug GO:0042493 3 0.037
heterocycle metabolic process GO:0046483 290 0.037
regulation of reproductive process GO:2000241 4 0.036
organic cyclic compound metabolic process GO:1901360 301 0.036
phagocytosis GO:0006909 3 0.035
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.035
neuron development GO:0048666 262 0.034
system process GO:0003008 185 0.034
cellular component morphogenesis GO:0032989 336 0.034
camera type eye development GO:0043010 222 0.034
regulation of multicellular organismal process GO:0051239 277 0.034
regulation of glial cell differentiation GO:0045685 4 0.033
axon guidance GO:0007411 86 0.033
regulation of localization GO:0032879 104 0.032
extrinsic apoptotic signaling pathway GO:0097191 3 0.032
cell projection organization GO:0030030 284 0.031
cell projection morphogenesis GO:0048858 244 0.031
cellular ketone metabolic process GO:0042180 11 0.031
immune system process GO:0002376 241 0.031
response to vitamin GO:0033273 3 0.031
i kappab kinase nf kappab signaling GO:0007249 4 0.031
regulation of metal ion transport GO:0010959 4 0.030
cellular response to external stimulus GO:0071496 2 0.030
amine metabolic process GO:0009308 2 0.029
cell morphogenesis involved in differentiation GO:0000904 195 0.029
signal transduction GO:0007165 455 0.028
regulation of cellular metabolic process GO:0031323 320 0.028
programmed cell death GO:0012501 119 0.028
regulation of gene expression GO:0010468 265 0.028
larval development GO:0002164 2 0.028
regulation of protein targeting GO:1903533 2 0.027
protein localization to nucleus GO:0034504 3 0.027
maintenance of location GO:0051235 4 0.027
neuroblast proliferation GO:0007405 2 0.027
homeostatic process GO:0042592 142 0.026
chordate embryonic development GO:0043009 271 0.026
negative regulation of cellular process GO:0048523 283 0.026
sprouting angiogenesis GO:0002040 53 0.026
heart development GO:0007507 313 0.026
regulation of purine nucleotide catabolic process GO:0033121 2 0.025
negative regulation of protein transport GO:0051224 3 0.025
regulation of gtp catabolic process GO:0033124 2 0.025
regulation of primary metabolic process GO:0080090 311 0.025
phosphorus metabolic process GO:0006793 109 0.025
apoptotic process GO:0006915 116 0.025
centrosome organization GO:0051297 1 0.024
sympathetic nervous system development GO:0048485 3 0.024
lipid homeostasis GO:0055088 3 0.024
morphogenesis of an epithelium GO:0002009 333 0.024
nucleic acid templated transcription GO:0097659 181 0.024
regulation of macromolecule metabolic process GO:0060255 317 0.024
eye morphogenesis GO:0048592 144 0.024
blood vessel development GO:0001568 246 0.023
phagocytosis engulfment GO:0006911 1 0.023
regulation of metabolic process GO:0019222 359 0.023
regulation of nucleotide catabolic process GO:0030811 2 0.023
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.023
single organism transport GO:0044765 206 0.023
liver development GO:0001889 96 0.023
peptide transport GO:0015833 1 0.023
regulation of establishment of protein localization GO:0070201 4 0.022
cellular biosynthetic process GO:0044249 286 0.022
immune system development GO:0002520 191 0.022
rna metabolic process GO:0016070 219 0.022
regulation of cell communication GO:0010646 232 0.022
regulation of cytokine production GO:0001817 3 0.022
axonogenesis GO:0007409 152 0.022
cell morphogenesis GO:0000902 289 0.022
nucleobase containing compound metabolic process GO:0006139 274 0.022
aging GO:0007568 2 0.022
proteasomal protein catabolic process GO:0010498 2 0.021
organonitrogen compound metabolic process GO:1901564 74 0.021
chemosensory behavior GO:0007635 1 0.021
regulation of protein transport GO:0051223 3 0.021
neuron projection development GO:0031175 180 0.021
smooth muscle contraction GO:0006939 2 0.021
heterocycle biosynthetic process GO:0018130 215 0.021
regulation of nucleoside metabolic process GO:0009118 2 0.021
embryonic skeletal system development GO:0048706 97 0.021
axon development GO:0061564 166 0.021
protein import into nucleus GO:0006606 3 0.021
regulation of protein binding GO:0043393 3 0.021
regionalization GO:0003002 274 0.021
organelle organization GO:0006996 227 0.021
regulation of protein localization to nucleus GO:1900180 2 0.021
transport GO:0006810 220 0.021
cellular amine metabolic process GO:0044106 2 0.021
cell part morphogenesis GO:0032990 246 0.020
peripheral nervous system neuron differentiation GO:0048934 28 0.020
regulation of organ growth GO:0046620 3 0.020
cell proliferation GO:0008283 80 0.020
aromatic compound biosynthetic process GO:0019438 217 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
homeostasis of number of cells within a tissue GO:0048873 4 0.020
regulation of calcium ion transport GO:0051924 2 0.020
transmission of nerve impulse GO:0019226 19 0.020
nerve development GO:0021675 45 0.019
regulation of tube size GO:0035150 2 0.019
hepaticobiliary system development GO:0061008 98 0.019
neuroblast differentiation GO:0014016 1 0.019
cellular component disassembly GO:0022411 1 0.019
meiotic nuclear division GO:0007126 4 0.019
regulation of cell activation GO:0050865 1 0.019
digestive system development GO:0055123 289 0.019
protein complex localization GO:0031503 1 0.019
regulation of macromolecule biosynthetic process GO:0010556 225 0.019
stem cell division GO:0017145 1 0.019
organic substance biosynthetic process GO:1901576 289 0.018
membrane invagination GO:0010324 1 0.018
cellular aromatic compound metabolic process GO:0006725 295 0.018
gene expression GO:0010467 252 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
developmental growth involved in morphogenesis GO:0060560 86 0.018
skeletal system morphogenesis GO:0048705 102 0.018
leukocyte proliferation GO:0070661 1 0.018
response to nutrient GO:0007584 3 0.018
chemotaxis GO:0006935 104 0.018
adult behavior GO:0030534 2 0.018
multi organism process GO:0051704 134 0.018
single organism organelle organization GO:1902589 199 0.018
nuclear transport GO:0051169 4 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
protein secretion GO:0009306 1 0.018
neuron neuron synaptic transmission GO:0007270 1 0.018
regulation of gtpase activity GO:0043087 2 0.018
secondary metabolic process GO:0019748 3 0.018
b cell mediated immunity GO:0019724 3 0.018
death GO:0016265 121 0.017
single organism localization GO:1902578 225 0.017
response to cold GO:0009409 4 0.017
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.017
heart morphogenesis GO:0003007 156 0.017
stem cell maintenance GO:0019827 4 0.017
tube morphogenesis GO:0035239 349 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
regulation of developmental process GO:0050793 247 0.017
regulation of binding GO:0051098 3 0.016
proximal distal pattern formation GO:0009954 1 0.016
positive regulation of cell cycle GO:0045787 3 0.016
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.016
regulation of cell shape GO:0008360 1 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
energy reserve metabolic process GO:0006112 2 0.016
positive regulation of epithelial cell migration GO:0010634 2 0.016
regulation of blood vessel size GO:0050880 2 0.016
posterior lateral line neuromast development GO:0048919 20 0.016
regulation of signal transduction GO:0009966 225 0.015
regulation of signaling GO:0023051 235 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
regulation of cell differentiation GO:0045595 142 0.015
circulatory system process GO:0003013 87 0.015
positive regulation of catabolic process GO:0009896 4 0.015
response to uv GO:0009411 3 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
sensory organ morphogenesis GO:0090596 200 0.015
nephron morphogenesis GO:0072028 2 0.015
neuron projection morphogenesis GO:0048812 161 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
rna biosynthetic process GO:0032774 181 0.015
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.015
embryonic skeletal joint morphogenesis GO:0060272 3 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.015
macromolecule biosynthetic process GO:0009059 227 0.015
regulation of phosphate metabolic process GO:0019220 43 0.015
negative regulation of cytoplasmic transport GO:1903650 2 0.015
multi organism cellular process GO:0044764 2 0.015
cellular response to starvation GO:0009267 1 0.015
small molecule metabolic process GO:0044281 77 0.015
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
response to glucocorticoid GO:0051384 1 0.014
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
nucleic acid metabolic process GO:0090304 244 0.014
biosynthetic process GO:0009058 294 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
embryonic heart tube development GO:0035050 133 0.014
sensory perception GO:0007600 39 0.014
taxis GO:0042330 109 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
hemopoiesis GO:0030097 183 0.014
compound eye development GO:0048749 2 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
positive regulation of secretion GO:0051047 1 0.014
blood circulation GO:0008015 87 0.014
mononuclear cell proliferation GO:0032943 1 0.014
lymphocyte proliferation GO:0046651 1 0.014
positive regulation of biological process GO:0048518 253 0.014
protein targeting to nucleus GO:0044744 3 0.014
positive regulation of myeloid cell differentiation GO:0045639 2 0.014
autophagy GO:0006914 4 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
regulation of glucose import GO:0046324 1 0.014
nucleoside monophosphate catabolic process GO:0009125 4 0.013
organic acid metabolic process GO:0006082 31 0.013
nuclear import GO:0051170 3 0.013
cell death GO:0008219 121 0.013
adherens junction organization GO:0034332 4 0.013
embryonic skeletal system morphogenesis GO:0048704 93 0.013
positive regulation of neuron death GO:1901216 1 0.013
cellular response to oxygen levels GO:0071453 1 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
specification of axis polarity GO:0065001 4 0.013
cranial nerve development GO:0021545 42 0.013
developmental programmed cell death GO:0010623 4 0.013
establishment or maintenance of bipolar cell polarity GO:0061245 12 0.013
protein import GO:0017038 3 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
regulation of cell death GO:0010941 103 0.013
single organism nuclear import GO:1902593 3 0.013
positive regulation of immune effector process GO:0002699 3 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
embryonic skeletal joint development GO:0072498 3 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
negative regulation of sequestering of calcium ion GO:0051283 4 0.013
protein polyubiquitination GO:0000209 4 0.013
myeloid cell differentiation GO:0030099 86 0.013
olfactory lobe development GO:0021988 4 0.013
growth GO:0040007 174 0.013
positive regulation of leukocyte differentiation GO:1902107 1 0.013
cell cycle GO:0007049 93 0.013
positive regulation of cytokine production GO:0001819 2 0.013
digestive system process GO:0022600 9 0.013
negative regulation of metabolic process GO:0009892 86 0.013
intracellular signal transduction GO:0035556 85 0.013
positive regulation of muscle cell differentiation GO:0051149 1 0.013
positive regulation of cell activation GO:0050867 1 0.012
endodermal cell fate determination GO:0007493 2 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
spermatid differentiation GO:0048515 2 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
appendage development GO:0048736 80 0.012
segmentation GO:0035282 97 0.012
digestive tract morphogenesis GO:0048546 231 0.012
multicellular organismal signaling GO:0035637 22 0.012
forebrain development GO:0030900 96 0.012
neuromuscular process controlling balance GO:0050885 3 0.012
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.012
collateral sprouting in absence of injury GO:0048669 4 0.012
cellular protein catabolic process GO:0044257 4 0.012
mitochondrion organization GO:0007005 4 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
cytoskeleton organization GO:0007010 96 0.012
negative regulation of cytokine production GO:0001818 1 0.012
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.012
camera type eye morphogenesis GO:0048593 108 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
response to stress GO:0006950 263 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
positive regulation of cell division GO:0051781 2 0.012
reactive oxygen species metabolic process GO:0072593 6 0.012
hypothalamus cell differentiation GO:0021979 4 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
regulation of circadian rhythm GO:0042752 4 0.011
regulation of response to cytokine stimulus GO:0060759 3 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
regulation of multicellular organism growth GO:0040014 4 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
inner ear development GO:0048839 126 0.011
oxoacid metabolic process GO:0043436 31 0.011
regulation of biosynthetic process GO:0009889 250 0.011
meiosis i GO:0007127 1 0.011
digestive tract mesoderm development GO:0007502 1 0.011
angiogenesis GO:0001525 158 0.011
cellular response to nutrient levels GO:0031669 2 0.011
mechanosensory lateral line system development GO:0048881 49 0.011
regulation of muscle contraction GO:0006937 3 0.011
canonical wnt signaling pathway GO:0060070 48 0.011
atp catabolic process GO:0006200 4 0.011
positive regulation of developmental process GO:0051094 50 0.011
response to corticosteroid GO:0031960 1 0.011
regulation of response to stimulus GO:0048583 269 0.011
response to other organism GO:0051707 97 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
membrane fusion GO:0061025 2 0.011
hatching GO:0035188 4 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
histone h3 k4 methylation GO:0051568 2 0.011
asymmetric protein localization GO:0008105 6 0.011
positive regulation of cellular component biogenesis GO:0044089 3 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
urogenital system development GO:0001655 97 0.011
regulation of cellular component movement GO:0051270 55 0.011
leukocyte homeostasis GO:0001776 2 0.011
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
negative regulation of myeloid cell differentiation GO:0045638 1 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
regulation of protein complex assembly GO:0043254 3 0.011
neural precursor cell proliferation GO:0061351 20 0.011
exocytosis GO:0006887 1 0.011
response to oxygen containing compound GO:1901700 55 0.011
apoptotic process involved in development GO:1902742 2 0.011
megakaryocyte differentiation GO:0030219 1 0.010
somatic cell dna recombination GO:0016444 1 0.010
macromolecule modification GO:0043412 111 0.010
cellular response to decreased oxygen levels GO:0036294 1 0.010
signal transduction in absence of ligand GO:0038034 1 0.010
mitotic dna integrity checkpoint GO:0044774 4 0.010
sensory perception of pain GO:0019233 1 0.010
negative regulation of protein localization to nucleus GO:1900181 2 0.010
regulation of transcription dna templated GO:0006355 213 0.010
establishment or maintenance of cell polarity GO:0007163 29 0.010
embryo development ending in birth or egg hatching GO:0009792 271 0.010
defense response to fungus GO:0050832 2 0.010
protein metabolic process GO:0019538 183 0.010
negative regulation of protein import into nucleus GO:0042308 2 0.010
ectodermal placode morphogenesis GO:0071697 32 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.010
tissue remodeling GO:0048771 4 0.010
cellular amide metabolic process GO:0043603 4 0.010
regulation of inflammatory response GO:0050727 2 0.010
cellular response to biotic stimulus GO:0071216 3 0.010
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
transcription dna templated GO:0006351 181 0.010
skin development GO:0043588 54 0.010
cell fate commitment GO:0045165 99 0.010
peptide metabolic process GO:0006518 1 0.010
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.010

ngfrl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.081
nervous system disease DOID:863 0 0.025
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
musculoskeletal system disease DOID:17 0 0.017
connective tissue disease DOID:65 0 0.017
organ system cancer DOID:0050686 0 0.016
bone disease DOID:0080001 0 0.014
gastrointestinal system cancer DOID:3119 0 0.012
disease of metabolism DOID:0014667 0 0.010
sensory system disease DOID:0050155 0 0.010